Published Data Registry

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TitleAuthorsJournalPublication year
DOI
PMID
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models(Open Access) Saleem HN, Ignatyeva N, Stuut C, Jakobs S, Habeck M, Ebert ACells2024
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach(Open Access) Dreha‐Kulaczewski S, Sahoo P, (...), Gärtner JJournal of Inherited Metabolic Disease2024
H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6(Open Access) Sokpor G, Kerimoglu C, (...), Tuoc TBiology (Basel)2024
Chemical synthesis of site-selective advanced glycation end products in α-synuclein and its fragmentsBosbach C, Gatzemeier LM, (...), Outeiro TFOrganic & Biomolecular Chemistry2024
Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatmentXu X, Tan X, (...), Hasenfuß GCardiovascular Research2024
Transient Non-local Interactions Dominate the Dynamics of Measles Virus N TAIL(Open Access) Otteson L, Nagy G, (...), Vaiana SMbioRxiv2024
Power-law adaptation in the presynaptic vesicle cycle(Open Access) Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli S, Priesemann VbioRxiv2024
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites(Open Access) Antonicka H, Weraarpachai W, Vučković A, Hillen HS, Shoubridge EAbioRxiv2024
Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response(Open Access) Hendrickson T, Abigail Giese A, (...), Altamirano FbioRxiv2024
Calcium-triggered (de)ubiquitination events in synapses(Open Access) Ainatzi S, Kaufmann SV, (...), Urlaub HbioRxiv2024
Dysferlin Enables Tubular Membrane Proliferation in Cardiac HypertrophyPaulke NJ, Fleischhacker C, (...), Brandenburg SCirculation Research2024
Early mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants in Chile(Open Access) Oróstica KY, Mohr SB, (...), Contreras SScientific Reports2024
Preparing primary sandwich hippocampal neuron cultures for cryo-electron tomography v1(Open Access) Domart F, Petrovic A, Do TT, Siegert A, Dresbach T, Fernández-Busnadiego Rprotocols.io2024
Synthesis and Semi‐Synthesis of Alpha‐Synuclein: Insight into the Chemical Complexity of Synucleinopathies(Open Access) Gatzemeier LM, Meyer F, Outeiro TFChemBioChem2024
Distributional limits of graph cuts on discretized grids(Open Access) Suchan L, Li H, Munk AarXiv2024
Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation(Open Access) Kim R, Nagel SH, Liaw NY, Zimmermann W, Zelarayán LC, Schoger EStem Cell Research2024
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes(Open Access) Amedei H, Paul NB, (...), Lenz CFrontiers in Analytical Science2024
A versatile yeast model identifies the pesticides cymoxanil and metalaxyl as risk factors for synucleinopathies(Open Access) Amaral L, Mendes F, Côrte-Real M, Rego A, Outeiro TF, Chaves SRChemosphere2024
Visible and near-infrared light-induced photoclick reactionsFu Y, Simeth NA, Szymanski W, Feringa BLNature Reviews Chemistry2024
Visualizing chaperonin function in situ by cryo-electron tomography(Open Access) Wagner J, Carvajal AI, (...), Hartl FUNature2024
Optical control of pH via chromoselective photodosimetry(Open Access) Chaudhuri A, Eijsink LE, Simeth NAChemical Communications2024
A Technique to Perform Structure–Function Analysis of SynapsesWichmann C, Michanski SNeuromethods2024
Blood‐derived microRNAs are related to cognitive domains in the general population(Open Access) Melas K, Talevi V, (...), Breteler MMBAlzheimers & Dementia2024
Bleaching protection and axial sectioning in fluorescence nanoscopy through two-photon activation at 515 nm(Open Access) Bredfeldt J, Oracz J, (...), Hell SWNature Communications2024
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish(Open Access) Bornhorst D, Hejjaji AV, (...), Gunawan FNature Communications2024
Towards sustainable research data management of longitudinal, heterogeneous data from cardiac tissue engineering(Open Access) Smolorz SA, Dittrich GM, (...), Kusch HGerman Medical Science GMS Publishing House2024
Rational approximation of golden angles: Accelerated reconstructions for radial MRI(Open Access) Scholand N, Schaten P, (...), Uecker MMagnetic Resonance in Medicine2024
KRASG12C‐inhibitor‐based combination therapies for pancreatic cancer: insights from drug screening(Open Access) Tapia Contreras C, Falke JD, (...), Schneider GMolecular Oncology2024
MultiMatch: geometry-informed colocalization in multi-color super-resolution microscopy(Open Access) Naas J, Nies G, (...), Munk ACommunications Biology2024
The plasma miRNAome in ADNI: Signatures to aid the detection of at‐risk individuals(Open Access) Krüger DM, Pena‐Centeno T, (...), Fischer AAlzheimers & Dementia2024
Volumetric changes of the enteric nervous system under physiological and pathological conditions measured using x‐ray phase‐contrast tomography(Open Access) Peruzzi N, Eckermann M, Frohn J, Salditt T, Ohlsson B, Bech MJGH Open2024
Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers(Open Access) Liu S, Park T, (...), Nho KAlzheimers & Dementia2024
Sustainable Data Management for Single-Cell Sequencing: Tools, Platforms, and Challenges(Open Access) Rosenboom N, Kossen R, Sax U, Nussbeck SY, Kusch HGerman Medical Science GMS Publishing House2024
Multiplex Microscopy Assay for Assessment of Therapeutic and Serum Antibodies against Emerging Pathogens(Open Access) Sartingen N, Stürmer V, (...), Laketa VViruses2024
Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity(Open Access) Karagulyan N, Überegger M, (...), Bandtlow CbioRxiv2024
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts(Open Access) Ruiz-Orera J, Miller DC, (...), Hübner NNature Cardiovascular Research2024
MALDI imaging combined with two-photon microscopy reveals local differences in the heterogeneity of colorectal cancer(Open Access) Bharti A, Ajinkya K, (...), Oliver Knpj Imaging2024
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid(Open Access) Aubrey LD, Ninkina N, (...), Radford SEProceedings of the National Academy of Sciences of the United States of America2024
Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylaseSievers K, Neumann P, (...), Ficner RStructure2024
Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes(Open Access) Paasche A, Wiedmann F, (...), Schmidt CBasic Research in Cardiology2024
Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins(Open Access) Eria-Oliveira A, Folacci M, (...), Vivaudou MNature Communications2024
Local Water Content in Polymer Gels Measured With Super‐Resolved Fluorescence Lifetime ImagingJana S, Nevskyi O, (...), Wöll DAngewandte Chemie-International Edition2024
Thermogenetics for cardiac pacing(Open Access) Balatskiy AV, Nesterenko AM, (...), Belousov VVbioRxiv2024
Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CMRapöhn M, Cyganek L, Voigt N, Hasenfuß G, Lehnart SE, Wegener JWAmerican Journal of Physiology-Heart and Circulatory Physiology2024
Image restoration of degraded time-lapse microscopy data mediated by near-infrared imaging(Open Access) Gritti N, Power RM, Graves A, Huisken JNature Methods2024
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria(Open Access) Poerschke S, Oeljeklaus S, (...), Rehling PMolecular Cell2024
Rational Approximation of Golden Angles for Simple and Reproducible Radial Sampling(Open Access) Scholand N, Graf C, Mackner D, Holme HCM, Uecker MarXiv2024
Uncovering potential diagnostic and pathophysiological roles of α‐synuclein and DJ‐1 in melanoma(Open Access) Quesnel A, Martin LD, (...), Filippou PSCancer Medicine2024
Drosophila MIC10b can polymerize into cristae-shaping filaments(Open Access) Stephan T, Stoldt S, (...), Jakobs SLife Science Alliance2024
Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing(Open Access) Reichmann J, Sarrazin C, (...), Salditt TbioRxiv2024
Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes(Open Access) Schmidt J, Kaulfuß S, (...), Wollnik BHuman Genetics2024
Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations(Open Access) Alfken J, Neuhaus C, (...), Salditt TEuropean Physical Journal E2024
High throughput methods for cardiac cellular electrophysiology studies: The road to personalized medicineSeibertz F, Voigt NAmerican Journal of Physiology-Heart and Circulatory Physiology2024
Genome engineering of a neuronal specific, optogenetic, induced pluripotent stem cell line(Open Access) Schmoll AK, Mager T, Tse TP, Alameldeen A, Zimmermann W, Zafeiriou MStem Cell Research2024
Characterizing ATP processing by the AAA+ protein p97 at the atomic level(Open Access) Shein M, Hitzenberger M, (...), Schütz AKNature Chemistry2024
Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1(Open Access) Düring J, Wolter M, (...), Lorenz SNature Structural & Molecular Biology2024
CryoRhodopsins: a comprehensive characterization of a new clade of microbial rhodopsins from cold environments(Open Access) Lamm G, Marin E, (...), Kovalev KbioRxiv2024
Metal-Induced Energy Transfer (MIET) Imaging of Cell Surface Engineering with Multivalent DNA NanobrushesWang D, Liu B, (...), Chen TACS Nano2024
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants(Open Access) Knauer C, Haltern H, (...), Cyganek LMolecular Therapy-Nucleic Acids2024
Model-Based Reconstruction for Joint Estimation of $T_{1}$, $R_{2}^{*}$ and $B_{0}$ Field Maps Using Single-Shot Inversion-Recovery Multi-Echo Radial FLASH(Open Access) Wang X, Scholand N, (...), Uecker MarXiv2024
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fractionGotthardt M, Lehnart SECardiovascular Research2024
In-situ architecture of the human prohibitin complex(Open Access) Lange F, Ratz M, (...), Jakobs SbioRxiv2024
Mouse oocytes sequester aggregated proteins in degradative super-organelles(Open Access) Zaffagnini G, Cheng S, (...), Böke ECell2024
Near-optimal information relay by the neuronal population of layer 4 barrel cortex(Open Access) Revah O, Wolf F, Gutnick MJ, Neef AbioRxiv2024
A metabolically controlled contact site between vacuoles and lipid droplets in yeast(Open Access) Diep DTV, Collado J, (...), Bohnert MDevelopmental Cell2024
RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis(Open Access) Prusty AB, Hirmer A, (...), Fischer UCell Reports2024
Human serum-derived α-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons(Open Access) Garg P, Würtz F, (...), Bähr MJournal of Neuroinflammation2024
Inhibition of 26S proteasome activity by α‐synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1(Open Access) Galka D, Ali TT, (...), Braus GHAging Cell2024
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy(Open Access) Schwenzer N, Tsukanov R, (...), Lehnart SEbioRxiv2024
Measuring sub-nanometer undulations at microsecond temporal resolution with metal- and graphene-induced energy transfer spectroscopy(Open Access) Chen T, Karedla N, Enderlein JNature Communications2024
Structure of the multi-subunit chloroplast RNA polymerase(Open Access) do Prado PF, Ahrens FM, (...), Hillen HSMolecular Cell2024
MultiMatch: Geometry-Informed Colocalization in Multi-Color Super-Resolution Microscopy(Open Access) Naas J, Nies G, (...), Munk AbioRxiv2024
Variance sum rule for entropy productionDi Terlizzi I, Gironella M, (...), Ritort FScience2024
Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing(Open Access) Salditt T, Reichmann J, (...), Balkema-Buschmann AResearchsquare2024
Synphilin-1 as a modulator of aSyn assembly(Open Access) Lázaro DF, Amen T, (...), Outeiro TFbioRxiv2024
3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes(Open Access) Pochechueva TV, Schwenzer N, (...), Lehnart SEInternational Journal of Molecular Sciences2024
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression(Open Access) Xu M, Ito-Kureha T, (...), Heissmeyer VNature Communications2024
Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies(Open Access) Sridhar S, Vystrčilová M, (...), Gollisch TbioRxiv2024
Convolutional neural network models of the primate retina reveal adaptation to natural stimulus statistics(Open Access) Vystrčilová M, Sridhar S, Burg MF, Gollisch T, Ecker ASbioRxiv2024
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)(Open Access) Frieg B, Han M, (...), Schröder GFNature Communications2024
A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise(Open Access) Methi A, Islam MR, (...), Fischer AMolecular Neurobiology2024
Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopyD’Amico L, Svetlove A, (...), Dullin CComputers in Biology and Medicine2024
Most discriminative stimuli for functional cell type clustering(Open Access) Burg MF, Zenkel T, (...), Ecker ASarXiv2024
Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions(Open Access) Bloothooft M, Verbruggen B, Seibertz F, Heyden MAGvd, Voigt N, de Boer TPFrontiers in Physiology2024
Biallelic NAA60 variants with impaired n-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications(Open Access) Chelban V, Aksnes H, (...), Houlden HNature Communications2024
mtDNA Analysis using Mitopore(Open Access) Dobner J, Nguyen T, (...), Rossi AMolecular Therapy-Methods & Clinical Development2024
NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals(Open Access) Mougios N, Cotroneo ER, (...), Opazo FbioRxiv2024
Hörvermögen wiederherstellen mit OptogenetikMoser TSprache-Stimme-Gehör2024
Adsorption of alpha-synuclein and inhibition of fibril formation by nanocellulose and gold-coated-nanocellulose(Open Access) Lamtar Mohammadi E, Keikha R, Outeiro TF, Jebali ACellulose2024
RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity(Open Access) Morici M, Gabrielli S, (...), Wilson DNNature Communications2024
Multiscale Quantile Regression with Local Error Control(Open Access) Liu Z, Li HarXiv2024
Formation of memory assemblies through the DNA-sensing TLR9 pathway(Open Access) Jovasevic V, Wood EM, (...), Radulovic JNature2024
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice(Open Access) Kaurani L, Islam MR, (...), Fischer AEMBO Journal2024
Gene therapy for deafness: are we there now?(Open Access) Moser T, Chen H, Kusch K, Behr R, Vona BEMBO Molecular Medicine2024
Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures(Open Access) Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF, Geraldes VBiomedicines2024
Robust inference of cooperative behaviour of multiple ion channels in voltage-clamp recordings(Open Access) Requadt R, Fink M, Kubica P, Steinem C, Munk A, Li HarXiv2024
[11C]MODAG 005 – a novel PET tracer targeting alpha-synuclein aggregates in the brain(Open Access) Saw RS, Buss S, (...), Herfert KResearchsquare2024
METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway(Open Access) Ma L, Zhou X, (...), Pan YCell Death & Disease2024
Structural basis of Integrator-dependent RNA polymerase II termination(Open Access) Fianu I, Ochmann M, (...), Cramer PNature2024
Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion(Open Access) López-Murcia FJ, Lin K, (...), Taschenberger HProceedings of the National Academy of Sciences of the United States of America2024
Molecular basis of human nuclear and mitochondrial tRNA 3'-processing(Open Access) Bhatta A, Kuhle B, (...), Hillen HbioRxiv2024
Super-resolution going viral: T4 virus particles as perfect nature-designed 3D-Bio-NanoRulers(Open Access) Gallea JI, Nevskyi O, (...), Enderlein JbioRxiv2024
How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNAHöbartner C, Bohnsack KE, Bohnsack MTAnnual Review of Biochemistry2024
Computational functions of precisely balanced neuronal assemblies in an olfactory memory network(Open Access) Meissner-Bernard C, Jenkins B, (...), Frank TbioRxiv2024
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway(Open Access) Oliveira da Silva MI, Santejo M, (...), Liz MACell Death & Disease2024
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathyWali R, Xu H, (...), Ebert ABiological Chemistry2024
Insights into cochlear structure by innovative light sheet fluorescence microscopy(Open Access) Roos L, Aakthe M, (...), Moser TLaryngo-Rhino-Otologie2024
In situ studies of membrane biology by cryo-electron tomography(Open Access) Keller J, Fernández-Busnadiego RCurrent Opinion in Cell Biology2024
Myosin II actively regulates Drosophila proprioceptors(Open Access) Guan C, Nishi K, Kreis CT, Bäumchen O, Göpfert MC, Schmidt CFbioRxiv2024
A role for astrocytic miR-129-5p in Frontotemporal Dementia(Open Access) Kaurani L, Pradhan R, (...), Fischer AbioRxiv2024
Microtubules: highway to … arrhythmia?(Open Access) Liutkute A, Prosser BL, Voigt NCardiovascular Research2024
Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment(Open Access) Weigel M, Dechent P, (...), Granziera CbioRxiv2024
Profiling the LAM family of contact site tethers provides insights into their regulation and function(Open Access) Fenech EJ, Kupervaser M, (...), Schuldiner MbioRxiv2024
Click Chemistry with Cell-Permeable Fluorophores Expands the Choice of Bioorthogonal Markers for Two-Color Live-Cell STED Nanoscopy(Open Access) Gregor C, Grimm F, Rehman J, Wurm CA, Egner ACells2024
A subgroup of light-driven sodium pumps with an additional Schiff base counterion(Open Access) Podoliak E, Lamm GHU, (...), Kovalev KNature Communications2024
Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy(Open Access) Gligonov I, Enderlein JbioRxiv2024
Toward Optogenetic Hearing RestorationHuet A, Mager T, Gossler C, Moser TAnnual Review of Neuroscience2024
Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice(Open Access) Outeiro TF, Kalia LV, (...), Svenningsson PMovement Disorders2024
Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT(Open Access) Oleksiievets N, Mougios N, (...), Tsukanov RbioRxiv2024
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation(Open Access) Maurer W, Rebs S, (...), Streckfuss-Bömeke KStem Cell Research2024
Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues(Open Access) Arora B, Kulkarni A, (...), Ramos-Gomes FScientific Reports2024
3D imaging of protein aggregates in human neurodegeneration by multiscale X-ray phase-contrast tomography(Open Access) Reichmann J, Franz J, Eckermann M, Stadelmann C, Salditt TmedRxiv2024
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts(Open Access) Foo B, Amedei H, (...), Lehnart SEbioRxiv2024
The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome(Open Access) Gersteuer F, Morici M, (...), Wilson DNNature Communications2024
A small step towards an important goal: fragment screen of the c-di-AMP-synthesizing enzyme CdaA(Open Access) Neumann P, Heidemann JL, (...), Ficner RActa Crystallographica Section D-Structural Biology2024
An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells(Open Access) Chen J, Stephan T, (...), Chen ZProceedings of the National Academy of Sciences of the United States of America2024
Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders(Open Access) Poschmann J, Solomon P, (...), Heilbronner UResearchsquare2024
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match(Open Access) Bock LV, Igaev M, Grubmüller HCurrent Opinion in Structural Biology2024
Through the Haze: Unveiling the Link Between Smoking and Atrial FibrillationMason FE, Voigt NAmerican Journal of Physiology-Heart and Circulatory Physiology2024
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling(Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LCCommunications Biology2024
CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy(Open Access) Schwenzer N, Teiwes NK, (...), Steinem CCommunications Biology2024
The molecular machinery for maturation of primary mtDNA transcripts(Open Access) Vučković A, Freyer C, Wredenberg A, Hillen HSHuman Molecular Genetics2024
Coordinating mitochondrial translation with assembly of the OXPHOS complexes(Open Access) Kremer LS, Rehling PHuman Molecular Genetics2024
CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release(Open Access) Velychko T, Mohammad E, (...), Lidschreiber MMolecular Cell2024
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implicationsBode D, Pronto JRD, Schiattarella GG, Voigt NNature Reviews Cardiology2024
Characterizing intracellular mechanics via optical tweezers-based microrheology(Open Access) Vos BE, Muenker TM, Betz TCurrent Opinion in Cell Biology2024
Catching up but still miles behind—a patient registry for otoferlin(Open Access) Vona B, Wollnik B, Strenzke N, Moser TExperimental & Molecular Medicine2024
Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresisSchröder S, Epple R, Fischer A, Schettler VJJTherapeutic Apheresis and Dialysis2024
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system(Open Access) Raimi OG, Ojha H, (...), Muqit MMKScience Advances2024
GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases(Open Access) Hsieh T, Lesmann H, (...), Olinger EResearchsquare2024
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity(Open Access) Harasimov K, Gorry RL, (...), Schuh MNature Cell Biology2024
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS(Open Access) Chatterjee M, Özdemir S, (...), Schneider ANature Medicine2024
Autonomous bioluminescence emission from transgenic mice(Open Access) Kiszka KA, Dullin C, (...), Gregor CbioRxiv2024
X-ray phase-contrast tomography of cells manipulated with an optical stretcher(Open Access) Burchert J, Frohn J, (...), Köster SJournal of Synchrotron Radiation2024
Lysosomal signalling pathways influence heart rhythm, and regulate atrial function(Open Access) Capel RA, Akerman E, (...), Burton RABbioRxiv2024
Open Problem: Active Representation Learning(Open Access) Milosevic N, Müller G, Huisken J, Scherf NarXiv2024
Lipidic folding pathway of α-Synuclein via a toxic oligomer(Open Access) Griesinger C, Sant V, (...), Andreas LResearchsquare2024
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice(Open Access) Edelman BJ, Siegenthaler D, (...), Macé EPLOS Biology2024
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial FibrillationFakuade FE, Hubricht D, (...), Voigt NCirculation2024
Aging and neurodegeneration: From molecular mechanisms to therapeutic interventions(Open Access) Outeiro TF, Brocardo PS, Gelain DPJournal of Neurochemistry2024
Structural insights into the regulation of RyR1 by S100A1(Open Access) Weninger G, Miotto MC, (...), Marks ARProceedings of the National Academy of Sciences of the United States of America2024
Interfering with aggregated α-synuclein in advanced melanoma leads to a major upregulation of MHC class II proteinsFokken C, Silbern I, (...), Becker DMelanoma Research2024
A roadmap for ribosome assembly in human mitochondria(Open Access) Lavdovskaia E, Hanitsch E, (...), Richter-Dennerlein RNature Structural & Molecular Biology2024
Neurofilament Light Chain Serum Levels Mirror Age and Disability in Secondary Progressive Multiple Sclerosis(Open Access) Husseini L, Jung J, (...), Weber MSNeurology Neuroimmunology & Neuroinflammation2024
Microlens arrays for multichannel laser-to-waveguide couplingKunze K, Gossler C, Peters V, Keppeler D, Moser T, Schwarz UTApplied Optics2024
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study(Open Access) Talevi V, Melas K, (...), Breteler MMJournal of Translational Medicine2024
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome(Open Access) Busley AV, Gutiérrez-Gutiérrez O, (...), Cyganek LCell Reports2024
Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis(Open Access) Schulte T, Chaves-Sanjuan A, (...), Ricagno SNature Communications2024
Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses(Open Access) Vasili E, König A, (...), Outeiro TFbioRxiv2024
PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer’s Disease(Open Access) Schröder S, Fuchs U, (...), Fischer AbioRxiv2024
Accessing activity and viscoelastic properties of artificial and living systems from passive measurementMuenker TM, Knotz G, Krüger M, Betz TNature Materials2024
Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopyRadmacher N, Nevskyi O, (...), Enderlein JNature Photonics2024
Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications to ion channels(Open Access) Jula Vanegas L, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk AAnnals of Applied Statistics2024
Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons(Open Access) Riemenschneider H, Guo Q, (...), Edbauer DEMBO Reports2024
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse(Open Access) Hain PJH, Moser TFrontiers in Molecular Neuroscience2024
CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells(Open Access) Oestreicher D, Chepurwar S, (...), Pangrsic TeLife2024
3D imaging of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography enables drug testing(Open Access) Reichmann J, Sarrazin C, (...), Salditt TScientific Reports2024
Machine learning and advanced statistical analysis for fluorescence correlation spectroscopyEnderlein JBiophysical Journal2024
Towards a biological diagnosis of PD(Open Access) Chopra A, Lang AE, Höglinger G, Outeiro TFParkinsonism Relat Disord2024
Live cell Imaging of yeast cells expressing human PINK1-GFP and the TOM complex subunits v1(Open Access) Ehses Kprotocols.io2024
Establishing synthetic ribbon-type active zones in a heterologous expression system(Open Access) Kapoor R, Schwenzer N, Dresbach T, Lehnart SE, Moser TeLife2024
Establishing synthetic ribbon-type active zones in a heterologous expression system(Open Access) Kapoor R, Schwenzer N, Dresbach T, Lehnart SE, Moser TbioRxiv2024
Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina(Open Access) Zapp SJ, Khani MH, (...), Gollisch TbioRxiv2024
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes(Open Access) Amedei H, Paul N, (...), Lenz CbioRxiv2024
The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites(Open Access) Zung N, Aravindan N, (...), Schuldiner MbioRxiv2024
Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88(Open Access) Lauer SM, Reepmeyer M, (...), Hoffmann RNature Communications2024
Circulating microRNAs are related to cognitive domains in the general population(Open Access) Melas K, Talevi V, (...), Breteler MMmedRxiv2024
Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain(Open Access) Herwerth M, Wyss MT, (...), Weber BbioRxiv2024
Autophagy preferentially degrades non-fibrillar polyQ aggregates(Open Access) Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling FMolecular Cell2024
Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness(Open Access) Haertter D, Hauke L, Driehorst T, Nishi K, Zimmermann W, Schmidt CFbioRxiv2024
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver(Open Access) Aich A, Patrick G, Rehling PZenodo2024
Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings(Open Access) Michael M, Wolf BJ, Klinge-Strahl A, Jeschke M, Moser T, Dieter ABrain Stimulation2023
The unique biomechanics of intermediate filaments – From single filaments to cells and tissuesRölleke U, Kumari P, Meyer R, Köster SCurrent Opinion in Cell Biology2023
Tracking cell turnover in human brain using 15N-thymidine imaging mass spectrometry(Open Access) Roeder SS, Bonnin EA, (...), Huttner HBFrontiers in Neuroscience2023
PrP meets alpha‐synuclein: Molecular mechanisms and implications for disease(Open Access) Vieira TCRG, Barros CA, Domingues R, Outeiro TFJournal of Neurochemistry2023
High-resolution analysis of bound Ca2+ in neurons and synapses(Open Access) Bonnin EA, Golmohammadi A, Rehm R, Tetzlaff C, Rizzoli SOLife Science Alliance2023
Fluorophore position of headgroup-labeled Gb3 glycosphingolipids in lipid bilayersSocrier L, Sharma A, (...), Steinem CBiophysical Journal2023
FGFR1 variants contributed to families with tooth agenesis(Open Access) Yao S, Zhou X, (...), Pan YHuman Genomics2023
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria(Open Access) Klein AD, Outeiro TFNature Communications2023
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices(Open Access) Jentoft IM, Bäuerlein FJ, (...), Schuh MCell2023
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs(Open Access) Shi R, Reichardt M, (...), Brügmann TCardiovascular Research2023
An NFATc1/SMAD3/cJUN complex restricted to SMAD4-deficient pancreatic cancer guides rational therapiesHasselluhn MC, Schlösser D, (...), Hessmann EGastroenterology2023
Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis(Open Access) Khan A, Markus MA, Svetlove A, Hülsmann S, Alves F, Dullin CScientific Reports2023
Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome(Open Access) Kutschka I, Bertero E, (...), Dudek JBasic Research in Cardiology2023
Structure of the transcribing RNA polymerase II–Elongin complex(Open Access) Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer PNature Structural & Molecular Biology2023
Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders(Open Access) Kaiyrzhanov R, Rad A, (...), Maroofian RBrain2023
Approaching automation of multiple instance orchestration of the menoci web portal(Open Access) Freckmann L, Henke C, (...), Kusch HBausteine Forschungsdatenmanagement2023
Efficient and sustained optogenetic control of nervous and cardiac systems(Open Access) Zerche M, Hunniford V, (...), Moser TbioRxiv2023
Unraveling haplotype errors in the DFNA33 locus(Open Access) Vona B, Regele S, (...), Am Zehnhoff-Dinnesen AGFrontiers in Genetics2023
Prediction mismatch responses arise as corrections of a predictive spiking code(Open Access) van Driel K, Rudelt L, Priesemann V, Mikulasch FAbioRxiv2023
Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency(Open Access) Schlotawa L, Matysiak K, (...), Gärtner JNeuropediatrics2023
Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis.(Open Access) Ricagno S, Schulte T, (...), Palladini GResearchsquare2023
A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca 2+ uptake(Open Access) Wegener JW, Mitronova GY, (...), Lehnart SELife Science Alliance2023
Ca2+ regulation of glutamate release from inner hair cells of hearing mice(Open Access) Jaime Tobón LM, Moser TProceedings of the National Academy of Sciences of the United States of America2023
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity(Open Access) Altas B, Rhee H, (...), Kawabe HJournal of Cell Biology2023
Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach(Open Access) Svetlove A, Ritter CO, (...), Unterberg-Buchwald CEuropean Radiology Experimental2023
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in <i>Bacillus subtilis in vitro</i>(Open Access) Wicke D, Neumann P, (...), Stülke JNucleic Acids Research2023
Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus(Open Access) Hintze A, Lange F, (...), Wichmann CiScience2023
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing(Open Access) Schreiber M, Zafeiriou MStem Cell Research2023
Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing(Open Access) Chen H, Monga M, (...), Moser TProtein & Cell2023
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy(Open Access) Kyriakopoulou E, Versteeg D, (...), van Rooij ENature Cardiovascular Research2023
Protein nanobarcodes enable single-step multiplexed fluorescence imaging(Open Access) de Jong-Bolm D, Sadeghi M, (...), Rizzoli SOPLOS Biology2023
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners(Open Access) Kanwal N, Krogh N, (...), Bohnsack MNucleic Acids Research2023
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple SclerosisGalbusera R, Bahn E, (...), Granziera CNeurology2023
Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory SynapsesAltas B, Tuffy LP, (...), Poulopoulos ABiological Psychiatry2023
Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells(Open Access) Schreiber M, Zafeiriou MStem Cell Research2023
Protocol to develop force-generating human skeletal muscle organoids(Open Access) Shahriyari M, Rinn M, Hofemeier AD, Babych A, Zimmermann W, Tiburcy MSTAR Protocols2023
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell(Open Access) Cepeda AP, Ninov M, (...), Urlaub HMolecular & Cellular Proteomics2023
Implications for neutrophils in cardiac arrhythmiasHegemann N, Barth L, Doering Y, Voigt N, Grune JAmerican Journal of Physiology-Heart and Circulatory Physiology2023
Structure and dynamics of human cardiac fibroblast nanotubes(Open Access) Schmid-Herbstritt S, Stief G, (...), Rog-Zielinska EbioRxiv2023
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis(Open Access) Wicke D, Neumann P, (...), Stülke JbioRxiv2023
Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes(Open Access) Harasimov K, Uraji J, (...), Schuh MNature Cell Biology2023
Age-dependent structural reorganization of utricular ribbon synapses(Open Access) Michanski S, Henneck T, (...), Wichmann CFrontiers in Cell and Developmental Biology2023
Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls(Open Access) Senner F, Schneider-Axmann T, (...), Schulze TGSchizophrenia Research-Cognition2023
Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restorationZerche M, Wrobel C, Kusch K, Moser T, Mager TMolecular Therapy-Methods & Clinical Development2023
Correction to: Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism(Open Access) Wohlfarter Y, Eidelpes R, (...), Keller MACellular and Molecular Life Sciences2023
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons(Open Access) Weichard I, Taschenberger H, (...), Nerlich JProceedings of the National Academy of Sciences of the United States of America2023
Herzbeteiligung beo COVID-19: Makrophagen-getriebene Entzündung und Gefäßneubildung(Open Access) Werlein C, Ackermann M, (...), Jonigk DPneumologie2023
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly(Open Access) Schnabel F, Schuler E, (...), Yigit GHuman Genetics2023
Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility(Open Access) Liebe NL, Mey I, (...), Steinem CACS Applied Materials & Interfaces2023
Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins(Open Access) Hauke L, Isbaner S, (...), Enderlein JACS Nano2023
Minimax detection of localized signals in statistical inverse problemsPohlmann M, Werner F, Munk AInformation and Inference-A Journal of the IMA2023
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming(Open Access) Zhang Z, Wang X, (...), Hessmann ECellular and Molecular Gastroenterology and Hepatology2023
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins(Open Access) Schmidt A, Finegan T, (...), Peifer MMolecular Biology of the Cell2023
Roadmap for optical tweezers(Open Access) Volpe G, Maragò OM, (...), Swartzlander GAJournal of Physics-Photonics2023
Simulation of Complex Biomolecular Systems: The Ribosome Challenge(Open Access) Bock LV, Gabrielli S, Kolář MH, Grubmüller HAnnual Review of Biophysics2023
Statistical Analysis of Random Objects Via Metric Measure LaplaciansMordant G, Munk ASIAM Journal on Mathematics of Data Science2023
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity(Open Access) Stewart H, Lu Y, (...), Firth AEiScience2023
The Ultrametric Gromov–Wasserstein DistanceMémoli F, Munk A, Wan Z, Weitkamp CDiscrete & Computational Geometry2023
Cryo-EM for Structure Determination of Mitochondrial Ribosome SamplesHillen HSMethods in Molecular Biology2023
The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation(Open Access) Pikunov AV, Syunyaev RA, (...), Efimov IRbioRxiv2023
Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease”(Open Access) Outeiro TF, Alcalay RN, (...), Ferreira JJMovement Disorders2023
The promise of optogenetic arrhythmia termination(Open Access) Bruegmann T, Sacconi LJournal of Internal Medicine2023
Author Correction: Selective optogenetic control of Gq signaling using human Neuropsin(Open Access) Wagdi A, Malan D, (...), Bruegmann TNature Communications2023
Empirical Optimal Transport under Estimated Costs: Distributional Limits and Statistical Applications(Open Access) Hundrieser S, Mordant G, Weitkamp CA, Munk AarXiv2023
Translation Factor Accelerating Peptide Bond Formation on the Ribosome: EF-P and eIF5A as Entropic Catalysts and a Potential Drug Targets(Open Access) Mudryi V, Peske F, Rodnina MBBA Advances2023
Impact of the Euro 2020 championship on the spread of COVID-19(Open Access) Dehning J, Mohr SB, (...), Priesemann VNature Communications2023
Structural insights into human co-transcriptional cappingGarg G, Dienemann C, (...), Cramer PMolecular Cell2023
Trafficking proteins show limited differences in mobility across different postsynaptic spines(Open Access) Mougios N, Opazo F, Rizzoli SO, Reshetniak SiScience2023
Membrane-Bound Vimentin Filaments Reorganize and Elongate under Strain(Open Access) Nageswaran S, Haipeter J, Bodenschatz JFE, Meyer R, Köster S, Steinem CBiomacromolecules2023
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling(Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LCCommunications Biology2023
The long-loop recycling (LLR) of synaptic components as a question of economics(Open Access) Georgiev SV, Rizzoli SOMolecular and Cellular Neuroscience2023
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy(Open Access) Flores-Leon M, Outeiro TFActa Neuropathologica2023
Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes(Open Access) Chen T, Ghosh A, Enderlein JNano Letters2023
Force generation in human blood platelets by filamentous actomyosin structures(Open Access) Zelená A, Blumberg J, (...), Köster SBiophysical Journal2023
Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy(Open Access) Laitenberger O, Aspelmeier T, Staudt T, Geisler C, Munk A, Egner ANanomaterials2023
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users(Open Access) Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser TFrontiers in Neuroscience2023
Graded optogenetic activation of the auditory pathway for hearing restoration(Open Access) Mittring A, Moser T, Huet ABrain Stimulation2023
Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington’s Disease Effects in YAC128 Mice(Open Access) Plácido E, Gomes Welter P, (...), Brocardo PSInternational Journal of Molecular Sciences2023
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome(Open Access) Busley AV, Gutiérrez-Gutiérrez Ó, (...), Cyganek LbioRxiv2023
Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses(Open Access) Karagulyan N, Moser TFrontiers in Molecular Neuroscience2023
Natural stimuli drive concerted nonlinear responses in populations of retinal ganglion cells(Open Access) Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch TbioRxiv2023
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes(Open Access) Weber F, Klas S, (...), Cyganek LSocial Science Research Network2023
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease(Open Access) Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci AInternational Journal of Molecular Sciences2023
Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes(Open Access) Haro-Moreno JM, López-Pérez M, (...), Rodriguez-Valera FbioRxiv2023
X-ray phase-contrast 3D virtual histology characterises complex tissue architecture in colorectal cancer(Open Access) Svetlove A, Griebel T, (...), Dullin CFrontiers in Gastroenterology2023
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome(Open Access) Akol I, Izzo A, (...), Vogel TProceedings of the National Academy of Sciences of the United States of America2023
A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion(Open Access) Podoliak E, Lamm GHU, (...), Kovalev KbioRxiv2023
An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex(Open Access) Enz LS, Winkler A, (...), Schaeren-Wiemers NInternational Journal of Molecular Sciences2023
Synapsin condensation controls synaptic vesicle sequestering and dynamics(Open Access) Hoffmann C, Rentsch J, (...), Milovanovic DNature Communications2023
CaBP1 and 2 enable sustained CaV 1.3 calcium currents and synaptic transmission in inner hair cells(Open Access) Oestreicher D, Chepurwar S, (...), Pangrsic TbioRxiv2023
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system(Open Access) Saha I, Yuste-Checa P, (...), Hipp MSNature Communications2023
ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals(Open Access) Binotti B, Ninov M, (...), Jahn RAutophagy2023
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF(Open Access) Antoniou A, Auderset L, (...), Schneider ACell Reports2023
Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina(Open Access) Krüppel S, Khani MH, (...), Gollisch TbioRxiv2023
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency(Open Access) Schlotawa L, Tyka K, (...), Gärtner JEMBO Molecular Medicine2023
HAV‐Peptides Attached to Colloidal Probes Faithfully Detect E‐Cadherins Displayed on Living Cells(Open Access) Toy S, Dietz J, (...), Janshoff AChemistry-A European Journal2023
Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reactionFu Y, Simeth NA, Toyoda R, Brilmayer R, Szymanski W, Feringa BLAngewandte Chemie-International Edition2023
Lysinuric protein intolerance caused by a homozygous SLC7A7 deletion and presented with hyperferritinemia and osteoporosis in two siblings(Open Access) Kalay I, Aykut H, Caliskan Z, Yigit G, Wollnik BMolecular Genetics and Metabolism Reports2023
Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism(Open Access) Grammatika Pavlidou N, Dobrev S, (...), Molina CEEuropean Heart Journal2023
Probing the role of the C2F domain of otoferlin(Open Access) Chen H, Fang Q, Benseler F, Brose N, Moser TFrontiers in Molecular Neuroscience2023
Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis(Open Access) Sant'Anna R, Robbs BK, (...), Foguel DbioRxiv2023
Spliceosome malfunction causes neurodevelopmental disorders with overlapping features(Open Access) Li D, Wang Q, (...), Hakonarson HJournal of Clinical Investigation2023
Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts(Open Access) Castro-Hernández R, Berulava T, (...), Fischer AProceedings of the National Academy of Sciences of the United States of America2023
The multifaceted mitochondrial OXA insertase(Open Access) Homberg B, Rehling P, Cruz-Zaragoza LDTrends in Cell Biology2023
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system(Open Access) Raimi OG, Ojha H, (...), Muqit MMKbioRxiv2023
Defective COX1 expression in aging mice liver(Open Access) Witte S, Boshnakovska A, Özdemir M, Chowdhury A, Rehling P, Aich ABiology Open2023
Observation of E-cadherin Adherens Junction Dynamics with Metal-Induced Energy Transfer Imaging and Spectroscopy(Open Access) Chen T, Karedla N, Enderlein JbioRxiv2023
In vitro reconstitution of chromatin domains(Open Access) Quililan K, Oberbeckmann E, Cramer P, Oudelaar AMbioRxiv2023
Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation(Open Access) Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes VCells2023
SparseProp: Efficient Event-Based Simulation and Training of Sparse Recurrent Spiking Neural Networks(Open Access) Engelken RarXiv2023
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies(Open Access) Hoffmann J, Hanß S, (...), Nauck NClinical Research in Cardiology2023
Excitation Intensity-Dependent Quantum Yield of Semiconductor Nanocrystals(Open Access) Ghosh S, Ross U, (...), Chizhik AIJournal of Physical Chemistry Letters2023
Impact of Phosphorylation on alpha-Synuclein Structural Determinants(Open Access) Dorn AE, de Bruyn E, (...), Carloni PbioRxiv2023
A quantitative fluorescence‐based approach to study mitochondrial protein import(Open Access) Jain N, Gomkale R, Bernhard O, Rehling P, Cruz‐Zaragoza LDEMBO reports2023
Mit Lichtstrahlen das Gehör wiederherstellen(Open Access) Moser TZeitschrift für Audiologie-Audiological Acoustics2023
Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channelPan Y, Pohjolainen E, (...), Scheuring SNature Structural & Molecular Biology2023
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain(Open Access) Schilbach S, Wang H, Dienemann C, Cramer PProceedings of the National Academy of Sciences of the United States of America2023
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes(Open Access) Seibertz F, Sutanto H, (...), Voigt NBasic Research in Cardiology2023
Towards a Biological Definition of Parkinson’s Disease(Open Access) Höglinger GU, Adler CH, (...), Lang AEPreprints2023
Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR(Open Access) Dervişoğlu R, Antonschmidt L, (...), Andreas LBMethods2023
Reverse-time analysis uncovers universality classes in directional biological dynamics(Open Access) Lenner N, Eule S, Großhans J, Wolf FarXiv2023
Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise(Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf FarXiv2023
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons(Open Access) Weichard I, Taschenberger H, (...), Nerlich JbioRxiv2023
C1q is increased in cerebrospinal fluid‐derived extracellular vesicles in Alzheimer's disease: A multi‐cohort proteomics and immuno‐assay validation study(Open Access) Chatterjee M, Özdemir S, (...), Schneider AAlzheimers & Dementia2023
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination(Open Access) Kapell H, Fazio L, (...), Schirmer LJournal of Clinical Investigation2023
Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation(Open Access) Gatzemeier LM, Meyer F, Diederichsen U, Outeiro TFChemistry-A European Journal2023
A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia(Open Access) Kaurani L, Islam MR, (...), Fischer AbioRxiv2023
Bayesian MRI reconstruction with joint uncertainty estimation using diffusion models(Open Access) Luo G, Blumenthal M, Heide M, Uecker MMagnetic Resonance in Medicine2023
A small-angle X-ray scattering study of red blood cells in continuous flow(Open Access) Burchert J, Graceffa R, Saldanha O, Burghammer M, Köster SJournal of Synchrotron Radiation2023
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart(Open Access) Nanadikar MS, Vergel Leon AM, (...), Katschinski DMNature Communications2023
Zelltypen aus menschlichen pluripotenten Zellen und deren Anwendung in ZelltherapienZimmermann W, Ader M, (...), Tonn TGen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft2023
3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis(Open Access) Frost J, Schmitzer B, (...), Salditt TNeuroscience2023
The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments(Open Access) Stephan T, Stoldt S, (...), Jakobs SbioRxiv2023
A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag(Open Access) Kim D, Stoldt S, Weber M, Jakobs S, Belov VN, Hell SWChemistry–Methods2023
Influence of phosphorylation on intermediate filamentsKraxner J, Köster SBiological Chemistry2023
Signatures of heterogeneity in the statistical structure of target state aligned ensembles(Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf FarXiv2023
Adaptive minimax optimality in statistical inverse problems via SOLIT -- Sharp Optimal Lepskii-Inspired Tuning(Open Access) Li H, Werner FarXiv2023
Quantitative MRI by nonlinear inversion of the Bloch equations(Open Access) Scholand N, Wang X, Roeloffs V, Rosenzweig S, Uecker MMagnetic Resonance in Medicine2023
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V(Open Access) Busley AV, Kleinsorge M, Cyganek LStem Cell Research2023
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V(Open Access) Busley AV, Cyganek LStem Cell Research2023
The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued(Open Access) Schröder S, Yigit G, (...), Brockmann KOrphanet Journal of Rare Diseases2023
Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis(Open Access) Pinkert-Leetsch D, Frohn J, Ströbel P, Alves F, Salditt T, Missbach-Guentner JCancer Imaging2023
A metabolically controlled contact site between lipid droplets and vacuoles(Open Access) Diep DTV, Collado JF, (...), Bohnert MbioRxiv2023
Vimentin intermediate filaments structure and mechanically support microtubules in cells(Open Access) Blob A, Ventzke D, (...), Köster SbioRxiv2023
Protein transport along the presequence pathwayMakki A, Rehling PBiological Chemistry2023
Structural basis of catalytic activation in human splicing(Open Access) Schmitzová J, Cretu C, Dienemann C, Urlaub H, Pena VNature2023
Decoding and Recoding of mRNA Sequences by the Ribosome(Open Access) Rodnina MVAnnual Review of Biophysics2023
Human lung virtual histology by multi-scale x-ray phase-contrast computed tomography(Open Access) Reichmann J, Verleden SE, (...), Salditt TPhysics in Medicine & Biology2023
Fluorescence Spectroscopy in Planar Dielectric and Metallic SystemsChizhik AI, Ruhlandt D, Enderlein JPhotonic Quantum Technologies2023
In vitro and in vivo characterization of improved channelrhodopsin ChRmine variants for optogenetic activation of the auditory pathwayZerche M, Hunniford V, Witzke I, Wolf B, Mager T, Moser TLaryngo-Rhino-Otologie2023
Characterization of novel channelrhodopsin variants for blue-light optogenetic activation of the auditory pathwayRoos L, Garrido-Charles A, Wolf B, Kusch K, Mager T, Moser TLaryngo-Rhino-Otologie2023
From emergency response to long-term management: the many faces of the endemic state of COVID-19(Open Access) Contreras S, Iftekhar EN, Priesemann VLancet Regional Health - Europe2023
Cytochrome c oxidase biogenesis – from translation to early assembly of the core subunit COX1(Open Access) Dennerlein S, Rehling P, Richter‐Dennerlein RFEBS Letters2023
Quick Adaptive Ternary Segmentation: An Efficient Decoding Procedure For Hidden Markov Models(Open Access) Mösching A, Li H, Munk AarXiv2023
N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing(Open Access) Wang C, Ulryck N, (...), Graille MNucleic Acids Research2023
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in CardiomyocytesDai Y, Ignatyeva N, (...), Ebert ACirculation Research2023
Investigating human lung tissue by propagation-based phase-contrast X-ray tomography(Open Access) Reichmann J, Verleden S, (...), Salditt TLEAPS Meets Life Sciences Conference (14.05.-19.05, Elba), Bioimaging2023
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcriptsRouvière JO, Salerno-Kochan A, (...), Jensen THMolecular Cell2023
Physiology of intracellular calcium bufferingEisner D, Neher E, Taschenberger H, Smith GPhysiological Reviews2023
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues(Open Access) Nakhaei-Rad S, Haghighi F, (...), Ahmadian MRCommunications Biology2023
Convergence of Empirical Optimal Transport in Unbounded Settings(Open Access) Staudt T, Hundrieser SarXiv2023
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease(Open Access) Schäffner E, Bosch-Queralt M, (...), Stassart RMNature Neuroscience2023
Targeting Biomolecular Condensation and Protein Aggregation against CancerSilva JL, Foguel D, (...), de Oliveira GAPChemical Reviews2023
Mechanisms of inward transmembrane proton translocationKovalev K, Tsybrov F, (...), Gordeliy VNature Structural & Molecular Biology2023
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease(Open Access) Gasparotto J, Somensi N, (...), Gelain DPJournal of Neurochemistry2023
Translation termination in human mitochondria – substrate specificity of mitochondrial release factors(Open Access) Nadler F, Richter-Dennerlein RBiological Chemistry2023
AI and protein structure and function in neurological disease: relevance to disease managementOuteiro TF, Vieira TCRGNature Reviews Neurology2023
Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC)(Open Access) Priesmeier L, Schoger E, Cyganek L, Cecilia Zelarayán LStem Cell Research2023
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40)(Open Access) Frieg B, Han M, (...), Schröder GFbioRxiv2023
Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate RetinaKrüppel S, Khani MH, (...), Gollisch TJournal of Neuroscience2023
Infomorphic networks: Locally learning neural networks derived from partial information decomposition(Open Access) Graetz M, Makkeh A, Schneider AC, Ehrlich DA, Priesemann V, Wibral MarXiv2023
Hijacking of internal calcium dynamics by intracellularly residing rhodopsins(Open Access) Eria-Oliveira A, Folacci M, (...), Vivaudou MbioRxiv2023
Flotillin-associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes(Open Access) Haro-Moreno JM, López-Pérez M, (...), Rodriguez-Valera FmSystems2023
Modulating Secondary Structure Motifs through Photo‐labile Peptide Staples(Open Access) Lāce I, Bazzi S, (...), Simeth NAChembiochem2023
Measuring sub-nanometer fluctuations at microsecond temporal resolution with metal-and graphene-induced energy transfer spectroscopy(Open Access) Chen T, Karedla N, Enderlein JbioRxiv2023
Vicious Twins: RyR2 Dysfunction and Structural RemodelingVoigt N, Seibertz F, Fakuade FECirculation Research2023
Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging(Open Access) Markus MA, Ferrari DP, Alves F, Ramos-Gomes FBiomedical Optics Express2023
Metal-induced energy transfer (MIET) imaging of cell surface engineering with multivalent DNA nanobrushes(Open Access) Wang D, Liu B, (...), Chen TbioRxiv2023
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearingMichanski S, Kapoor R, (...), Wichmann CEMBO reports2023
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto‐axonal target in late‐stage Parkinson's disease(Open Access) Warth Perez Arias CC, Silbern I, (...), Lingor PJournal of Neurochemistry2023
Multiscale scanning with nuisance parameters(Open Access) König C, Munk A, Werner FarXiv2023
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome(Open Access) Chowdhury A, Boshnakovska A, (...), Rehling PEMBO Molecular Medicine2023
Modulation of translational decoding by m6A modification of mRNA(Open Access) Jain S, Koziej L, (...), Rodnina MVNature Communications2023
Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosisMonteiro Neto JR, Ribeiro GD, Magalhães RS, Follmer C, Outeiro TF, Eleutherio ECBiochimica et Biophysica Acta-Molecular Basis of Disease2023
Structural conservation of antibiotic interaction with ribosomesPaternoga H, Crowe-McAuliffe C, (...), Wilson DNNature Structural & Molecular Biology2023
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathiesChopra A, Outeiro TFBrain2023
A viral ADP-ribosyltransferase attaches RNA chains to host proteins(Open Access) Wolfram-Schauerte M, Pozhydaieva N, (...), Höfer KNature2023
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis(Open Access) Sant’Anna R, Robbs BK, (...), Foguel DMolecular Medicine2023
DNA-Based Optical Sensors for Forces in Cytoskeletal NetworksJayachandran C, Ghosh A, (...), Schmidt CFACS Applied Nano Materials2023
Bioengineering of a human innervated cardiac muscle model(Open Access) Schneider LV, Bao G, (...), Zafeiriou MbioRxiv2023
Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine(Open Access) Mustroph J, Baier MJ, (...), Neef SCirculation2023
A scalable clustering algorithm to approximate graph cuts(Open Access) Suchan L, Li H, Munk AarXiv2023
Unravelling ATP processing by the AAA+ protein p97 at the atomic level(Open Access) Shein M, Hitzenberger M, (...), Schuetz AbioRxiv2023
En route to sound coding strategy for optical cochlear implants(Open Access) Khurana L, Harczos T, Moser T, Jablonski LiScience2023
Boosting of neural circuit chaos at the onset of collective oscillations(Open Access) Palmigiano A, Engelken R, Wolf FeLife2023
N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody(Open Access) Zibat A, Zhang X, (...), Dobbelstein MiScience2023
Segment Anything for Microscopy(Open Access) Archit A, Nair S, (...), Pape CbioRxiv2023
Intracellular mechanical fingerprint reveals cell type specific mechanical tuning(Open Access) Muenker TM, Vos BE, Betz TbioRxiv2023
Doubling the resolution of single-molecule localization microscopy with image scanning microscopy(Open Access) Radmacher N, Nevskyi O, (...), Enderlein JbioRxiv2023
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development(Open Access) Seibertz F, Rubio T, (...), Voigt NCardiovascular Research2023
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE)Oppermann Peixoto D, Bittencourt RR, (...), Pens Gelain DJournal of Neurochemistry2023
Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis(Open Access) Kanwischer L, Xu X, (...), Zeisberg EMClinical Epigenetics2023
Evaluating the association of biallelic OGDHL variants with significant phenotypic heterogeneity(Open Access) Lin S, Vona B, (...), Varshney GKGenome Medicine2023
Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression(Open Access) Kaurani L, Besse M, (...), Zilles-Wegner DTranslational Psychiatry2023
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis?(Open Access) Thümmler K, Wrzos C, (...), Linington CNeuropathology and Applied Neurobiology2023
Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclaseEgbert JR, Silbern I, (...), Jaffe LABiology of Reproduction2023
4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applications(Open Access) Goodarzi Hosseinabadi H, Biswas A, (...), Ionov LSmall2023
Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm(Open Access) Grahn E, Kaufmann SV, (...), Kaupp UNature Communications2023
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice(Open Access) Edelman B, Siegenthaler D, (...), Mace EbioRxiv2023
Approaching automation of multiple instance orchestration of the menoci web portal(Open Access) Freckmann L, Henke C, (...), Kusch HGerman Medical Science GMS Publishing House2023
Diversity matters - extending sound intensity coding by inner hair cells via heterogeneous synapses(Open Access) Moser T, Karagulyan N, Neef J, Jaime Tobón LMEMBO Journal2023
Cardiac multiscale bioimaging: from nano- through micro- to mesoscales(Open Access) Tolstik E, Lehnart SE, Soeller C, Lorenz K, Sacconi LTrends in Biotechnology2023
Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities(Open Access) Schaeper JJ, Liberman MC, Salditt TJournal of Medical Imaging2023
GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases(Open Access) Lesmann H, Hustinx A, (...), Hsieh TCmedRxiv2023
Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative AnalysisOleksiievets N, Mathew C, (...), Enderlein JNano Letters2022
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial(Open Access) Levin J, Sing N, (...), Giese AeBioMedicine2022
Remote control of the heart and beyondZimmermann WScience2022
A Mathematical Model for Electrical Activity in Pig Atrial Tissue(Open Access) Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder RFrontiers in Physiology2022
Allosteric control of Ubp6 and the proteasome via a bidirectional switch(Open Access) Hung KYS, Klumpe S, (...), Finley DNature Communications2022
WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephalyBögershausen N, Krawczyk HE, (...), Wollnik BHuman Mutation2022
Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration(Open Access) Liu JK, Karamanlis D, Gollisch TPLOS Computational Biology2022
Statistical spatial analysis for cryo-electron tomography(Open Access) Martinez-Sanchez A, Baumeister W, Lučić VComputer Methods and Programs in Biomedicine2022
Sequence determinants of human gene regulatory elements(Open Access) Sahu B, Hartonen T, (...), Taipale JNature Genetics2022
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control(Open Access) Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein RbioRxiv2022
Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants(Open Access) Khurana L, Keppeler D, Jablonski L, Moser TComputational and Structural Biotechnology Journal2022
Is there an unmet medical need for improved hearing restoration?Wolf BJ, Kusch K, (...), Moser TEMBO Molecular Medicine2022
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function(Open Access) Lin S, Vona B, (...), Varshney GKHuman Mutation2022
Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX(Open Access) Grabner CP, Jansen I, (...), Moser TScience Advances2022
Structure of a backtracked hexasomal intermediate of nucleosome transcriptionFarnung L, Ochmann M, Garg G, Vos SM, Cramer PMolecular Cell2022
Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology(Open Access) Chowdhury A, Witte S, Aich AFrontiers in Cell and Developmental Biology2022
HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation(Open Access) Fan Y, Murgia M, (...), Klein CJournal of Clinical Investigation2022
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43(Open Access) Heo D, Ling JP, (...), Bergles DEeLife2022
Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory(Open Access) Dombrowski M, Engeholm M, Dienemann C, Dodonova S, Cramer PNature Structural & Molecular Biology2022
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data(Open Access) Chen X, Sailer C, (...), Stengel FbioRxiv2022
Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice(Open Access) Svetlove A, Albers J, (...), Dullin CCells2022
α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals(Open Access) Leite K, Garg P, (...), Kügler SFrontiers in Molecular Neuroscience2022
The 3D structure of lipidic fibrils of α-synuclein(Open Access) Frieg B, Antonschmidt L, (...), Schröder GFbioRxiv2022
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes(Open Access) Chegão A, Guarda M, (...), Vicente Miranda Hnpj Parkinson's Disease2022
Production of Recombinant Alpha-Synuclein: Still No Standardized Protocol in Sight(Open Access) Al-Azzani M, König A, Outeiro TFBiomolecules2022
Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissuesSantos GL, DeGrave AN, (...), Lutz SBiomaterials Advances2022
Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3(Open Access) Baidoe-Ansah D, Sakib S, (...), Dityatev ACells2022
A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming(Open Access) Lyra-Leite DM, Gutiérrez-Gutiérrez O, Wang M, Zhou Y, Cyganek L, Burridge PWSTAR Protocols2022
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated SpeciesSantos CC, Cardim-Pires TR, (...), Silva VDANeurotoxicity Research2022
Multiscale architecture: Mechanics of composite cytoskeletal networks(Open Access) Lorenz C, Köster SBiophysics Reviews2022
Combined optical fluorescence microscopy andX-ray tomography reveals substructures in cellnuclei in 3D(Open Access) Wittmeier A, Bernhardt M, (...), Köster SBiomedical Optics Express2022
DNA-PAINT MINFLUX nanoscopy(Open Access) Ostersehlt LM, Jans DC, (...), Jakobs SNature Methods2022
IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter(Open Access) Katsenelson M, Shapira I, (...), Slutsky IProceedings of the National Academy of Sciences of the United States of America2022
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2(Open Access) Gregor CScientific Reports2022
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis(Open Access) Brandenburg S, Otto L, (...), Lehnart SEJournal of Molecular and Cellular Cardiology2022
Interdomain Dynamics via Paramagnetic NMR on the Highly Flexible Complex Calmodulin/Munc13-1(Open Access) Karschin N, Becker S, Griesinger CJournal of the American Chemical Society2022
The murine male reproductive organ at a glance: Three‐dimensional insights and virtual histology using label‐free light sheet microcopy(Open Access) Pinkert‐Leetsch D, Rost JU, Schmiedeknecht MUH, Stadelmann C, Alves F, Missbach‐Guentner JAndrology2022
Ectosomes and exosomes modulate neuronal spontaneous activityBrás IC, Khani MH, (...), Outeiro TFJournal of Proteomics2022
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes(Open Access) Seibertz F, Rapedius M, (...), Voigt NCommunications Biology2022
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II(Open Access) Rengachari S, Schilbach S, (...), Cramer PbioRxiv2022
Quantitative Magnetic Resonance Imaging by Nonlinear Inversion of the Bloch Equations(Open Access) Scholand N, Wang X, Roeloffs V, Rosenzweig S, Uecker MarXiv2022
A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry(Open Access) Li F, Fornasiero EF, Dankovich TM, Kluever V, Rizzoli SOInternational Journal of Molecular Sciences2022
A Sequential Two-Step Priming Scheme Reproduces Diversity in Synaptic Strength and Short-Term Plasticity(Open Access) Lin K, Taschenberger H, Neher ESocial Science Research Network2022
A Variational View on Statistical Multiscale EstimationHaltmeier M, Li H, Munk AAnnual Review of Statistics and Its Application2022
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways(Open Access) Schaffner SL, Wassouf Z, (...), Kobor MSHuman Molecular Genetics2022
Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts(Open Access) Castro-Hernández R, Berulava T, (...), Fischer AbioRxiv2022
Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients(Open Access) Haupt LP, Rebs S, (...), Streckfuss-Bömeke KBasic Research in Cardiology2022
Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice(Open Access) Dullin C, Svetlove A, Zschüntzsch J, Alves FScientific Reports2022
Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden(Open Access) Bhatta A, Hillen HSBIOspektrum2022
MRI Reconstruction via Data Driven Markov Chain with Joint Uncertainty Estimation(Open Access) Luo G, Heide M, Uecker MarXiv2022
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain(Open Access) Liu T, Stephan T, (...), Chen ZbioRxiv2022
Retinal Encoding of Natural ScenesKaramanlis D, Schreyer HM, Gollisch TAnnual Review of Vision Science2022
Synaptic transmission at the vestibular hair cells of amniotesMukhopadhyay M, Pangrsic TMolecular and Cellular Neuroscience2022
The Statistics of Circular Optimal Transport(Open Access) Hundrieser S, Klatt M, Munk AForum for Interdisciplinary Mathematics2022
Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs(Open Access) Nakhaei-Rad S, Bazgir F, (...), Ahmadian MRbioRxiv2022
Whole genome sequencing for newborns—The devil is in the details(Open Access) Vona BClinical and Translational Discovery2022
GGPS1‐associated muscular dystrophy with and without hearing loss(Open Access) Kaiyrzhanov R, Perry L, (...), Maroofian RAnnals of Clinical and Translational Neurology2022
Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study(Open Access) Lange T, Backhaus SJ, (...), Schuster AJournal of Cardiovascular Magnetic Resonance2022
Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease(Open Access) Seefelder M, Klein FA, Landwehrmeyer B, Fernández-Busnadiego R, Kochanek SJournal of Huntington's Disease2022
Electrophysiological Characterization of Microbial Rhodopsins by Patch-Clamp ExperimentsMager TMethods in Molecular Biology2022
Imaging of Autonomous Bioluminescence Emission From Single Mammalian CellsGregor CMethods in Molecular Biology2022
A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity(Open Access) Queiroz DD, Ribeiro TdP, (...), Pereira MDBiochimica et Biophysica Acta-Molecular Basis of Disease2022
Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices(Open Access) Veress B, Peruzzi N, (...), Ohlsson BWorld Journal of Gastroenterology2022
Expansion microscopy at one nanometer resolution(Open Access) Shaib AH, Chouaib AA, (...), Rizzoli SObioRxiv2022
Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules(Open Access) Chakraborty S, Martinez-Sanchez A, (...), Mahamid JbioRxiv2022
Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain(Open Access) Altas B, Tuffy LP, (...), Poulopoulos AbioRxiv2022
Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA A Rs and cytosolic gephyrin aggregation(Open Access) Zeppillo T, Ali H, (...), Krueger-Burg DbioRxiv2022
A sequential two-step priming scheme reproduces diversity in synaptic strength and short-term plasticity(Open Access) Lin K, Taschenberger H, Neher EProceedings of the National Academy of Sciences of the United States of America2022
Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina(Open Access) Nitsche S, Khani MH, (...), Gollisch TbioRxiv2022
From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms(Open Access) Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes VBiology-Basel2022
Structure of angiogenin dimer bound to double-stranded RNA(Open Access) Sievers K, Ficner RActa Crystallographica Section F-Structural Biology Communications2022
Roadmap for Optical Tweezers(Open Access) Volpe G, Maragò OM, (...), Swartzlander GAarXiv2022
Bridging the gap between presynaptic hair cell function and neural sound encoding(Open Access) Jaime Tobón LM, Moser TbioRxiv2022
From LUVs to GUVs - how to cover micrometer-sized pores with membranes(Open Access) Kramer K, Sari M, (...), Steinem CChemRxiv2022
Aneuploidy in mammalian oocytes and the impact of maternal ageingCharalambous C, Webster A, Schuh MNature Reviews Molecular Cell Biology2022
Graded optogenetic activation of the auditory pathway for neural network analysis and hearing restoration(Open Access) Mittring A, Moser T, Huet AbioRxiv2022
Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism(Open Access) Wohlfarter Y, Eidelpes R, (...), Keller MACellular and Molecular Life Sciences2022
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils(Open Access) Antonschmidt L, Matthes D, (...), Andreas LBNature Communications2022
Deep, deep learning with BART(Open Access) Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker MMagnetic Resonance in Medicine2022
Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease(Open Access) Dankovich TM, Rizzoli SOFrontiers in Cellular Neuroscience2022
Impact of native-like lipid membranes on the architecture and contractility of actomyosin networks(Open Access) Liebe NL, Mey I, Vuong L, Geil B, Janshoff A, Steinem CbioRxiv2022
There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments(Open Access) Rapedius M, Obergrussberger A, (...), Fertig NFrontiers in Molecular Neuroscience2022
In silico modeling for personalized stenting in aortic coarctation(Open Access) Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker MEngineering Applications of Computational Fluid Mechanics2022
A quantitative fluorescence-based approach to study mitochondrial protein import(Open Access) Jain N, Gomkale R, Bernhard O, Rehling P, Cruz-Zaragoza LDbioRxiv2022
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy(Open Access) Shahriyari M, Islam MR, (...), Tiburcy MJournal of Cachexia, Sarcopenia and Muscle2022
Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation(Open Access) Laubrock K, von Loesch T, (...), Unterberg-Buchwald CEuropean Journal of Radiology Open2022
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control(Open Access) Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein RNature Communications2022
Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous EnvironmentCorbet BP, Schlüter JM, Cotroneo ER, Crespi S, Simeth NAEuropean Journal of Organic Chemistry2022
Inflammation and vascular remodeling in COVID-19 hearts(Open Access) Werlein C, Ackermann M, (...), Jonigk DAngiogenesis2022
Cochlear Hair Cell Innervation is Dependent on a Modulatory Function of Semaphorin‐3ACantu‐Guerra HL, Papazian MR, (...), Coate TMDevelopmental Dynamics2022
Kantorovich–Rubinstein Distance and Barycenter for Finitely Supported Measures: Foundations and Algorithms(Open Access) Heinemann F, Klatt M, Munk AApplied Mathematics & Optimization2022
Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartmentCheng S, Altmeppen G, (...), Schuh MScience2022
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane(Open Access) Swaih AM, Breda C, (...), Giorgini FBiomedicines2022
Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling(Open Access) Paulke N, Amlaz S, (...), Brandenburg SEuropean Heart Journal2022
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita(Open Access) Schnabel F, Schuler E, (...), Yigit GResearchsquare2022
Graphene-Induced Energy Transfer for Quantitative Membrane Biophysics at Sub-Nanometer Resolution(Open Access) Chen T, Ghosh A, Enderlein JarXiv2022
Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag(Open Access) Steyer AM, Buscham TJ, (...), Werner HBGlia2022
Unbalanced Kantorovich-Rubinstein distance and barycenter for finitely supported measures: A statistical perspective(Open Access) Heinemann F, Klatt M, Munk AarXiv2022
New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain(Open Access) Weninger G, Lehnart SEJournal of Cellular Signaling2022
Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones(Open Access) Tan C, de Nola G, (...), Kaeser PSeLife2022
Structures of transcription preinitiation complex engaged with the +1 nucleosome(Open Access) Wang H, Schilbach S, Ninov M, Urlaub H, Cramer PNature Structural & Molecular Biology2022
Regulation of the mammalian-brain V-ATPase through ultraslow mode-switchingKosmidis E, Shuttle CG, (...), Stamou DNature2022
Editorial: Cardiac optogenetics: Using light to observe and excite the heart(Open Access) Bruegmann T, Smith GL, Lehnart SEFrontiers in Physiology2022
Targeting Mitochondrial Calcium Handling to Treat Atrial FibrillationVoigt N, Maack C, Pronto JRDJournal of the American College of Cardiology2022
Randomized Wasserstein Barycenter Computation: Resampling with Statistical GuaranteesHeinemann F, Munk A, Zemel YSIAM Journal on Mathematics of Data Science2022
Sampling effects and measurement overlap can bias the inference of neuronal avalanches(Open Access) Pinheiro Neto J, Spitzner FP, Priesemann VPLOS Computational Biology2022
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells(Open Access) Pavez-Giani MG, Cyganek LFrontiers in Cell and Developmental Biology2022
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp(Open Access) Rosholm KR, Badone B, (...), Bell DCFrontiers in Molecular Neuroscience2022
Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion(Open Access) Lāce I, Cotroneo ER, Hesselbarth N, Simeth NAJournal of Peptide Science2022
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis(Open Access) Galbusera R, Bahn E, (...), Granziera CBrain Pathology2022
Skeletal Class III Malocclusion Is Associated with ADAMTS2 Variants and Reduced Expression in a Familial Case(Open Access) Yao S, Zhou X, (...), Pan YInternational Journal of Molecular Sciences2022
Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli(Open Access) Shahidi N, Rozenblit F, (...), Gollisch TbioRxiv2022
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse(Open Access) Hain PJH, Moser TbioRxiv2022
Tackling the Dynamic Range Problem of Hearing: Diverse Hair Cell Synapses Enable Broad Neural Sound Intensity Coding(Open Access) Jaime Tobón LM, Moser TSocial Science Research Network2022
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II(Open Access) Rengachari S, Schilbach S, (...), Cramer PNature Structural & Molecular Biology2022
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine(Open Access) Schoger E, Lelek S, Panáková D, Zelarayán LCFrontiers in Cardiovascular Medicine2022
Free‐breathing myocardial T1 mapping using inversion‐recovery radial FLASH and motion‐resolved model‐based reconstruction(Open Access) Wang X, Rosenzweig S, (...), Uecker MMagnetic Resonance in Medicine2022
Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum(Open Access) Schmidt J, Dreha-Kulaczewski S, (...), Wollnik BFrontiers in Cell and Developmental Biology2022
The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic(Open Access) Dankovich TM, Rizzoli SOFrontiers in Synaptic Neuroscience2022
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity(Open Access) Stewart H, Lu Y, (...), Firth AEbioRxiv2022
The 3D structure of lipidic fibrils of α-synuclein(Open Access) Frieg B, Antonschmidt L, (...), Schröder GFNature Communications2022
Mono- and Intralink Filter (Mi-Filter) To Reduce False Identifications in Cross-Linking Mass Spectrometry Data(Open Access) Chen X, Sailer C, (...), Stengel FAnalytical Chemistry2022
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain(Open Access) Liu T, Stephan T, (...), Chen ZProceedings of the National Academy of Sciences of the United States of America2022
Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores(Open Access) Gregor C, Grimm F, Rehman J, Wurm CA, Egner AbioRxiv2022
Cotranslational Biogenesis of Membrane Proteins in Bacteria(Open Access) Mercier E, Wang X, Bögeholz LAK, Wintermeyer W, Rodnina MVFrontiers in Molecular Biosciences2022
Expanding the spectrum of EEF1D neurodevelopmental disorders: Biallelic variants in the Guanine Exchange DomainAverdunk L, Al‐Thihli K, (...), Wieczorek DClinical Genetics2022
On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants(Open Access) Helke C, Reinhardt M, (...), Reuter DMaterials2022
Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalitiesSchaeper JJ, Liberman MC, Salditt TDevelopments in X-Ray Tomography XIV2022
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies(Open Access) Koss DJ, Erskine D, (...), Outeiro TFActa Neuropathologica Communications2022
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses(Open Access) Chakrabarti R, Jaime Tobón LM, (...), Wichmann CeLife2022
From guide to guard—activation mechanism of the stress-sensing chaperone Get3(Open Access) Ulrich K, Farkas Á, Chan O, Katamanin O, Schwappach B, Jakob UMolecular Cell2022
A Measure of the Complexity of Neural Representations based on Partial Information Decomposition(Open Access) Ehrlich DA, Schneider AC, Priesemann V, Wibral M, Makkeh AarXiv2022
Prion-like α-synuclein pathology in the brain of infants with Krabbe diseaseHatton C, Ghanem SS, (...), Erskine DBrain2022
The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation(Open Access) Kleiber N, Lemus-Diaz N, (...), Bohnsack MTNature Communications2022
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes(Open Access) Brandenburg S, Pawlowitz J, (...), Lehnart SEJournal of Molecular and Cellular Cardiology2022
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells(Open Access) Oleksiievets N, Sargsyan Y, (...), Tsukanov RCommunications Biology2022
Age-dependent structural reorganization of utricular ribbon synapses(Open Access) Michanski S, Henneck T, (...), Wichmann CbioRxiv2022
The Role of Junctophilin Proteins in Cellular Function(Open Access) Lehnart SE, Wehrens XHPhysiological Reviews2022
On the Uniqueness of Kantorovich Potentials(Open Access) Staudt T, Hundrieser S, Munk AarXiv2022
A Molecular Pump Facilitates Mechanical Adsorption Away from EquilibriumSimeth NAAngewandte Chemie-International Edition2022
Dystrophin is a mechanical tension modulator(Open Access) Hofemeier AD, Muenker TM, (...), Betz TbioRxiv2022
Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria(Open Access) Chojnacka KJ, Elancheliyan P, (...), Chacińska AMolecular Biology of the Cell2022
Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal ActivityBrás IC, Khani MH, (...), Outeiro TFJournal of Parkinsons Disease2022
Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses(Open Access) Michanski S, Kapoor R, (...), Wichmann CbioRxiv2022
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells(Open Access) Vasili E, Dominguez-Meijide A, (...), Outeiro TFMolecular Neurobiology2022
Mechanism of spindle pole organization and instability in human oocytesSo C, Menelaou K, (...), Schuh MScience2022
Structural basis for safe and efficient energy conversion in a respiratory supercomplex(Open Access) Kao W, Ortmann de Percin Northumberland C, (...), Hunte CNature Communications2022
Real‐time radial tagging for quantification of left ventricular torsionMohammadi E, Nasiraei‐Moghaddam A, Uecker MMagnetic Resonance in Medicine2022
Rethinking opsins(Open Access) Feuda R, Menon AK, Göpfert MCMolecular Biology and Evolution2022
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures(Open Access) Gönenc II, Wolff A, (...), Wollnik BHuman Molecular Genetics2022
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds(Open Access) Saha I, Yuste-Checa P, (...), Hipp MSbioRxiv2022
Indole derivatives as core structural motifs in molecular organic photoactuators(Open Access) Simeth NA, Crespi S2022
Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy(Open Access) Wegner W, Steffens H, Gregor C, Wolf F, Willig KIeLife2022
Empirical Optimal Transport between Different Measures Adapts to Lower Complexity(Open Access) Hundrieser S, Staudt T, Munk AarXiv2022
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation(Open Access) Torres-Garcia L, P. Domingues JM, (...), Li JScientific Reports2022
A new form of axonal pathology in a spinal model of neuromyelitis optica(Open Access) Herwerth M, Kenet S, (...), Misgeld TBrain2022
Phenotypic spectrum of BLM and RMI1–related Bloom syndrome(Open Access) Gönenc II, Elcioglu NH, (...), Wollnik BClinical Genetics2022
Deep, Deep Learning with BART(Open Access) Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker MarXiv2022
A Unifying Approach to Distributional Limits for Empirical Optimal Transport(Open Access) Hundrieser S, Klatt M, Staudt T, Munk AarXiv2022
White matter integrity in mice requires continuous myelin synthesis at the inner tongue(Open Access) Meschkat M, Steyer AM, (...), Möbius WNature Communications2022
MemBrain: A Deep Learning-aided Pipeline for Automated Detection of Membrane Proteins in Cryo-electron Tomograms(Open Access) Lamm L, Righetto RD, (...), Engel BDbioRxiv2022
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease(Open Access) Shomroni O, Sitte M, (...), Salinas GScientific Reports2022
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3(Open Access) Upmanyu N, Jin J, (...), Sambandan SNeuron2022
Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene(Open Access) Pater JA, Penney C, (...), Young THuman Genetics2022
Modeling charge separation in charged nanochannels for single-molecule electrometryEnderlein J, Sakhapov D, Gregor I, Croci M, Karedla NJournal of Chemical Physics2022
Methods for multiscale structural and functional analysis of the mammalian cochleaVogl C, Neef J, Wichmann CMolecular and Cellular Neuroscience2022
Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition(Open Access) Farzadfard A, König A, (...), Otzen DEJournal of Biological Chemistry2022
Extracellular alpha-synuclein: Sensors, receptors, and responses(Open Access) Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TFNeurobiology of Disease2022
Selective optogenetic control of Gq signaling using human Neuropsin(Open Access) Wagdi A, Malan D, (...), Bruegmann TNature Communications2022
Boosting of neural circuit chaos at the onset of collective oscillations(Open Access) Palmigiano A, Engelken R, Wolf FbioRxiv2022
Roles and dynamics of 3-methylcytidine in cellular RNAs(Open Access) Bohnsack KE, Kleiber N, Lemus-Diaz N, Bohnsack MTTrends in Biochemical Sciences2022
Measuring photophysical transition rates with fluorescence correlation spectroscopy and antibunching(Open Access) Sakhapov D, Gregor I, Karedla N, Enderlein JarXiv2022
Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system(Open Access) Calapai A, Cabrera-Moreno J, Moser T, Jeschke MNature Communications2022
Optimal transfer functions for bandwidth-limited imaging(Open Access) Stallinga S, Radmacher N, Delon A, Enderlein JPhysical Review Research2022
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains(Open Access) Peña-Díaz S, Pujols J, (...), Ventura SJournal of Biological Chemistry2022
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation – A proof-of-concept studyJebran A, Tiburcy M, (...), Zimmermann WJournal of Molecular and Cellular Cardiology2022
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNSVincenti I, Page N, (...), Merkler DScience Translational Medicine2022
Statistical analysis of random objects via metric measure Laplacians(Open Access) Mordant G, Munk AarXiv2022
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration(Open Access) Luebben AV, Bender D, (...), Steinfeld RScience Advances2022
The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible(Open Access) Cassotta M, Geerts H, (...), Hogberg HTALTEX-Alternatives to Animal Experimentation2022
Seeded binary segmentation: a general methodology for fast and optimal changepoint detection(Open Access) Kovács S, Bühlmann P, Li H, Munk ABiometrika2022
Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance(Open Access) Ding Y, Korchak S, (...), Glöggler SChemistry–Methods2022
Free-Breathing Liver Fat, R₂* and B₀ Field Mapping Using Multi-Echo Radial FLASH and Regularized Model-Based ReconstructionTan Z, Unterberg-Buchwald C, (...), Uecker MIEEE Transactions on Medical Imaging2022
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons(Open Access) Riemenschneider H, Guo Q, (...), Edbauer DEMBO Reports2022
Statistical Methods for Minimax Estimation in Linear Models with Unknown Design Over Finite AlphabetsBehr M, Munk ASIAM Journal on Mathematics of Data Science2022
Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice(Open Access) Bali B, Gruber-Dujardin E, Kusch K, Rankovic V, Moser TLife Science Alliance2022
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy(Open Access) Jung P, Seibertz F, (...), Voigt NBasic Research in Cardiology2022
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses(Open Access) Chakrabarti R, Jaime Tobón LM, (...), Wichmann CbioRxiv2022
In silico modeling for personalized stenting in aortic coarctation(Open Access) Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker MarXiv2022
IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress(Open Access) Nanadikar M, Leon AV, (...), Katschinski DResearchsquare2022
Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea(Open Access) Garrido-Charles A, Huet A, (...), Gorostiza PJournal of the American Chemical Society2022
Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway(Open Access) Farkas A, Urlaub H, Bohnsack KE, Schwappach BJournal of Cell Biology2022
Identification and optimization of channelrhodopsin variants for optogenetic hearing restoration(Open Access) Zerche M, Moser T, Mager TLaryngo-Rhino-Otologie 20222022
In vivo investigation of f-Chrimson variants for optogenetic hearing restoration(Open Access) Wrobel C, Zerche M, Kusch K, Mager T, Moser TLaryngo-Rhino-Otologie 20222022
Distribution of Distances based Object Matching: Asymptotic InferenceWeitkamp CA, Proksch K, Tameling C, Munk AJournal of the American Statistical Association2022
Excited state lifetime modulation in semiconductor nanocrystals for super-resolution imaging(Open Access) Ghosh S, Hollingsworth J, Gallea JI, Majumder S, Enderlein J, Chizhik ANanotechnology2022
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart RepairTiburcy M, Meyer T, Satin P, Zimmermann WMethods in Molecular Biology2022
A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolutionElizarova S, Chouaib AA, (...), Daniel JAProceedings of the National Academy of Sciences of the United States of America2022
Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers(Open Access) Yudovich S, Marzouqe A, (...), Weiss SBiophysical Journal2022
Background calcium influx in arrhythmia: lead actor or extra?(Open Access) Fakuade FE, Fauconnier J, Voigt NJournal of Physiology-London2022
The relevance of synuclein autoantibodies as a biomarker for Parkinson's diseaseGarg P, Maass F, (...), Bähr MMolecular and Cellular Neuroscience2022
Not the classical serendipity: does doxapram treat atrial fibrillation?(Open Access) Liutkute A, Brundel BJ, Voigt NCardiovascular Research2022
Retinal receptive-field substructure: scaffolding for coding and computation(Open Access) Zapp SJ, Nitsche S, Gollisch TTrends in Neurosciences2022
Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome(Open Access) Schmidt J, Bremmer F, Brockmann K, Kaulfuß S, Wollnik BClinical Genetics2022
An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry(Open Access) Kabatas Glowacki S, Agüi-Gonzalez P, (...), Rizzoli SOChemical Communications2022
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel(Open Access) Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller HNucleic Acids Research2022
Effects of cryo-EM cooling on structural ensembles(Open Access) Bock LV, Grubmüller HNature Communications2022
Isotropic three-dimensional dual-color super-resolution microscopy with metal-induced energy transfer(Open Access) Thiele JC, Jungblut M, (...), Enderlein JScience Advances2022
Measuring Photophysical Transition Rates with Fluorescence Correlation Spectroscopy and AntibunchingSakhapov D, Gregor I, Karedla N, Enderlein JJournal of Physical Chemistry Letters2022
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells(Open Access) Xiong L, Tolen EA, (...), Schöler HReLife2022
Structural and mechanistic basis of RNA processing by protein-only ribonuclease P enzymes(Open Access) Bhatta A, Hillen HSTrends in Biochemical Sciences2022
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes(Open Access) Weninger G, Pochechueva T, (...), Lehnart SEScientific Reports2022
Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations(Open Access) Buratti FA, Boeffinger N, (...), Fernández COProtein Science2022
Distinct roles of the meningeal layers in CNS autoimmunityMerlini A, Haberl M, (...), Odoardi FNature Neuroscience2022
MemBrain: A Deep Learning-aided Pipeline for Detection of Membrane Proteins in Cryo-electron TomogramsLamm L, Righetto RD, (...), Engel BDComputer Methods and Programs in Biomedicine2022
Rapid multi-plane phase-contrast microscopy reveals torsional dynamics in flagellar motion(Open Access) Mojiri S, Isbaner S, (...), Enderlein JBiomedical Optics Express2021
Tejaas: reverse regression increases power for detecting trans-eQTLs(Open Access) Banerjee S, Simonetti FL, (...), Söding JGenome Biology2021
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis(Open Access) Kabinger F, Stiller C, (...), Cramer PbioRxiv2021
Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes(Open Access) Antonschmidt L, Dervişoğlu R, (...), Griesinger CScience Advances2021
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2(Open Access) Fianu I, Dienemann C, Aibara S, Schilbach S, Cramer PCommunications Biology2021
α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease(Open Access) Stuendl A, Kraus T, (...), Schneider AMovement Disorders2021
Multi-label in vivo STED microscopy by parallelized switching of reversibly switchable fluorescent proteins(Open Access) Willig KI, Wegner W, Müller A, Calvet-Fournier V, Steffens HCell Reports2021
Transmembrane β‐peptide helices as molecular rulers at the membrane surface(Open Access) Kloos M, Sharma A, Enderlein J, Diederichsen UJournal of Peptide Science2021
Graphene- and metal-induced energy transfer for single-molecule imaging and live-cell nanoscopy with (sub)-nanometer axial resolutionGhosh A, Chizhik AI, Karedla N, Enderlein JNature Protocols2021
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity(Open Access) Steffens H, Mott AC, (...), Willig KIScience Advances2021
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA openingSchilbach S, Aibara S, Dienemann C, Grabbe F, Cramer PCell2021
Structural basis of nucleosome transcription mediated by Chd1 and FACT(Open Access) Farnung L, Ochmann M, Engeholm M, Cramer PNature Structural & Molecular Biology2021
Radiative Rate Modulation Reveals Near‐Unity Quantum Yield of Graphene Quantum Dots(Open Access) Ghosh S, Oleksiievets N, Enderlein J, Chizhik AIAdvanced Optical Materials2021
Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis(Open Access) Bergner CG, Genc N, (...), Stadelmann CGlia2021
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1 tm1Kds mice and X-linked adrenoleukodystrophy patients(Open Access) Kettwig M, Klemp H, (...), Gärtner JJournal of Inherited Metabolic Disease2021
Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases(Open Access) Koss DJ, Campesan S, Giorgini F, Outeiro TFMovement Disorders2021
Analysis of patchclamp recordings: model-free multiscale methods and software(Open Access) Pein F, Eltzner B, Munk AEuropean Biophysics Journal2021
Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome(Open Access) Epple R, Krüger D, (...), Fischer AMolecular Neurobiology2021
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complexHuang B, Guo Q, (...), Fernández-Busnadiego RStructure2021
Pore-Spanning Plasma Membranes Derived from Giant Plasma Membrane VesiclesTeiwes NK, Mey I, Baumann PC, Strieker L, Unkelbach U, Steinem CACS Applied Materials & Interfaces2021
In situ architecture of neuronal α-Synuclein inclusions(Open Access) Trinkaus VA, Riera-Tur I, (...), Fernández-Busnadiego RNature Communications2021
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing(Open Access) Oberbeckmann E, Niebauer V, (...), Korber PNature Communications2021
IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter(Open Access) Katsenelson M, Shapira I, (...), Slutsky IbioRxiv2021
3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography(Open Access) Reichardt M, Jensen PM, (...), Salditt TbioRxiv2021
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology(Open Access) Kargapolova Y, Rehimi R, (...), Papantonis ANature Communications2021
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathyXu H, Wali R, (...), Ebert AFEBS Letters2021
MINSTED fluorescence localization and nanoscopy(Open Access) Weber M, Leutenegger M, (...), Hell SWNature Photonics2021
Structures of mammalian RNA polymerase II pre-initiation complexesAibara S, Schilbach S, Cramer PNature2021
Astrocytes control the spiking of mouse visual cortex layer 5 pyramidal neurons(Open Access) Sundaram SM, Garg P, Leßlich HM, Mathivanan SJournal of Physiology-London2021
Multiple haplotype reconstruction from allele frequency dataPelizzola M, Behr M, Li H, Munk A, Futschik ANature Computational Science2021
Physics-based reconstruction methods for magnetic resonance imaging(Open Access) Wang X, Tan Z, Scholand N, Roeloffs V, Uecker MPhilosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences2021
Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons(Open Access) Riemenschneider H, Guo Q, (...), Edbauer DbioRxiv2021
Sequence determinants of human gene regulatory elements(Open Access) Sahu B, Hartonen T, (...), Taipale JbioRxiv2021
RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse(Open Access) Butola T, Alvanos T, (...), Moser TbioRxiv2021
Dimeric form of SARS-CoV-2 polymerase(Open Access) Jochheim FA, Tegunov D, (...), Cramer PbioRxiv2021
A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites(Open Access) Elizarova S, Chouaib A, (...), Daniel JbioRxiv2021
Cryo-electron tomography of native Drosophila tissues vitrified by plunge freezing(Open Access) Bäuerlein FJ, Pastor-Pareja JC, Fernández-Busnadiego RbioRxiv2021
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel(Open Access) Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller HbioRxiv2021
Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain(Open Access) Weish P, Lazaro DF, (...), Outeiro TFbioRxiv2021
Instant three color multi-plane fluorescence microscopy(Open Access) Gregor I, Butkevich E, Enderlein J, Mojiri SbioRxiv2021
Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea(Open Access) Garrido-Charles A, Huet A, (...), Gorostiza PbioRxiv2021
Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy(Open Access) Grabner CP, Jansen I, (...), Moser TbioRxiv2021
Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways(Open Access) Schaffner SL, Wassouf Z, (...), Kobor MSbioRxiv2021
Structure of a transcribing RNA polymerase II–U1 snRNP complexZhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer PScience2021
A DNA-based optical force sensor for live-cell applicationsJayachandran C, Ghosh A, (...), Schmidt CFbioRxiv2021
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci(Open Access) Kyryachenko S, Georges A, (...), Bouatia-Naji NCirculation Research2021
Exercise Stress Real-Time Cardiac Magnetic Resonance Imaging for Noninvasive Characterization of Heart Failure With Preserved Ejection Fraction(Open Access) Backhaus SJ, Lange T, (...), Schuster ACirculation2021
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity(Open Access) Medina L, González-Lizárraga F, (...), Socias SBFrontiers in Aging Neuroscience2021
MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile(Open Access) Jacinto S, Guerreiro P, (...), Outeiro TFFrontiers in Cellular Neuroscience2021
Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants(Open Access) Huet AT, Dombrowski T, Rankovic V, Thirumalai A, Moser TFrontiers in Molecular Neuroscience2021
Posterior analysis of n in the binomial (n,p) problem with both parameters unknown -- with applications to quantitative nanoscopy(Open Access) Schmidt-Hieber J, Schneider LF, Staudt T, Krajina A, Aspelmeier T, Munk AarXiv2021
The ultrametric Gromov-Wasserstein distance(Open Access) Mémoli F, Munk A, Wan Z, Weitkamp CarXiv2021
Frame-constrained total variation regularization for white noise regression(Open Access) del Álamo M, Li H, Munk AAnnals of Statistics2021
The Statistics of Circular Optimal Transport(Open Access) Hundrieser S, Klatt M, Munk AarXiv2021
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2Gregor CbioRxiv2021
Limit Distributions and Sensitivity Analysis for Entropic Optimal Transport on Countable Spaces(Open Access) Hundrieser S, Klatt M, Munk AarXiv2021
Transport Dependency: Optimal Transport Based Dependency Measures(Open Access) Nies TG, Staudt T, Munk AarXiv2021
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state(Open Access) Yigit G, Sheffer R, (...), Brockmann KJournal of Medical Genetics2021
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spinesHelm MS, Dankovich TM, (...), Rizzoli SONature Neuroscience2021
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein(Open Access) Martinez Hernandez A, Silbern I, (...), Eichele GFrontiers in Neuroscience2021
Oct4 primarily controls enhancer activity rather than accessibility(Open Access) Xiong L, Tolen EA, (...), Schöler HRbioRxiv2021
Posterior analysis of n in the binomial (n,p) problem with both parameters unknown—with applications to quantitative nanoscopy(Open Access) Schmidt-Hieber J, Schneider LF, Staudt T, Krajina A, Aspelmeier T, Munk AAnnals of Statistics2021
Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils(Open Access) Joppe KDn, Tatenhorst L, (...), Lingor PJournal of Neurochemistry2021
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling(Open Access) Hillen HS, Lavdovskaia E, (...), Richter-Dennerlein RNature Communications2021
Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling(Open Access) Silbern I, Pan K, (...), Jahn RMolecular & Cellular Proteomics2021
What is resolution? A statistical minimax testing perspective on superresolution microscopy(Open Access) Kulaitis G, Munk A, Werner FAnnals of Statistics2021
Structure of the human Mediator–RNA polymerase II pre-initiation complexRengachari S, Schilbach S, Aibara S, Dienemann C, Cramer PNature2021
Structural and functional insights into human tRNA guanine transgylcosylaseSievers K, Welp L, Urlaub H, Ficner RRNA Biology2021
Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies(Open Access) Iqbal M, Maroofian R, (...), Yigit GGenetics in Medicine2021
isoSTED microscopy with water-immersion lenses and background reductionSiegmund R, Werner F, Jakobs S, Geisler C, Egner ABiophysical Journal2021
Statistical spatial analysis for cryo-electron tomography(Open Access) Martinez-Sanchez A, Baumeister W, Lučić VarXiv2021
Photophysical properties and fluorescence lifetime imaging of exfoliated near-infrared fluorescent silicate nanosheets(Open Access) Selvaggio G, Weitzel M, (...), Kruss SNanoscale Advances2021
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation(Open Access) Sadredini M, Haugsten Hansen M, (...), Stokke MKAmerican Journal of Physiology-Heart and Circulatory Physiology2021
Allosteric transcription stimulation by RNA polymerase II super elongation complexChen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer PMolecular Cell2021
Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells(Open Access) Brás IC, Khani MH, (...), Outeiro TFbioRxiv2021
Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors(Open Access) Cretu C, Gee P, (...), Pena VNature Communications2021
MFSD2A-associated primary microcephaly - Expanding the clinical and mutational spectrum of this ultra-rare diseaseKhuller K, Yigit G, (...), Kuechler AEuropean Journal of Medical Genetics2021
Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging(Open Access) Raja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh AbioRxiv2021
Advanced fluorescence correlation spectroscopy for studying biomolecular conformation(Open Access) Ghosh A, Enderlein JCurrent Opinion in Structural Biology2021
Organs-on-chip models for cardiovascular drug development(Open Access) Zimmermann WCardiovascular Research2021
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression(Open Access) Schoger E, Zimmermann W, Cyganek L, Zelarayán LCStem Cell Research2021
The structure of a dimeric form of SARS-CoV-2 polymerase(Open Access) Jochheim FA, Tegunov D, (...), Cramer PCommunications Biology2021
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo(Open Access) Thom T, Schmitz M, (...), Zerr IMovement Disorders2021
Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons(Open Access) Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SOScientific Reports2021
Structural basis of RNA processing by human mitochondrial RNase P(Open Access) Bhatta A, Dienemann C, Cramer P, Hillen HSNature Structural & Molecular Biology2021
Fibroblast Derived Human Engineered Connective Tissue for Screening ApplicationsSantos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz SJournal of Visualized Experiments2021
Structure of an inactive RNA polymerase II dimer(Open Access) Aibara S, Dienemann C, Cramer PNucleic Acids Research2021
Structural basis of human transcription–DNA repair coupling(Open Access) Kokic G, Wagner FR, Chernev A, Urlaub H, Cramer PNature2021
Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy(Open Access) Yigit G, Wollnik BMedizinische Genetik2021
H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion(Open Access) Kerimoglu C, Pham L, (...), Tuoc TScience Advances2021
RNF43 Pathogenic Germline Variant in a Family with Colorectal CancerMikaeel RR, Young JP, (...), Price TJClinical Genetics2021
Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration(Open Access) Liu JK, Gollisch TbioRxiv2021
Management of Metadata Types in Basic Cardiological Research(Open Access) Kusch H, Kossen R, (...), Nussbeck SYStudies in Health Technology and Informatics2021
The bumpy road of FAIRification in practice(Open Access) Kusch H, Bauer CR, (...), Sax UGerman Medical Science GMS Publishing House2021
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1(Open Access) Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MKPhysiological reports2021
Biallelic variants in YRDC cause a developmental disorder with progeroid features(Open Access) Schmidt J, Goergens J, (...), Wollnik BHuman Genetics2021
Mapping protein interactions in the active TOM-TIM23 supercomplex(Open Access) Gomkale R, Linden A, (...), Rehling PNature Communications2021
GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072(Open Access) Kusch H, Bauer CR, (...), Sax UGöttingen Research Online / Data2021
Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501(Open Access) Goldberg M, Islam MR, (...), Fischer ATranslational Psychiatry2021
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis(Open Access) Lavdovskaia E, Hillen HS, Richter-Dennerlein RTrends in Cell Biology2021
Familial cleft tongue caused by a unique translation initiation codon variant in TP63(Open Access) Schmidt J, Schreiber G, (...), Wollnik BEuropean Journal of Human Genetics2021
Intracellular softening and increased viscoelastic fluidity during division(Open Access) Hurst S, Vos BE, Brandt M, Betz TNature Physics2021
Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy(Open Access) Khan A, Ramos-Gomes F, Markus A, Mietsch M, Hinkel R, Alves FBiomedical Optics Express2021
An in vitro system to silence mitochondrial gene expression(Open Access) Cruz-Zaragoza LD, Dennerlein S, (...), Rehling PCell2021
A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease(Open Access) Shomroni O, Sitte M, (...), Salinas GResearchsquare2021
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy(Open Access) Bertero E, Nickel A, (...), Maack CCirculation2021
Instant three-color multiplane fluorescence microscopy(Open Access) Gregor I, Butkevich E, Enderlein J, Mojiri SBiophysical Reports2021
Structural basis of Integrator-mediated transcription regulationFianu I, Chen Y, (...), Cramer PScience2021
Effects of cryo-EM cooling on structural ensembles(Open Access) Bock LV, Grubmüller HbioRxiv2021
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy(Open Access) Kettwig M, Ternka K, (...), Gärtner JNature Communications2021
Exfoliation and Optical Properties of Near-Infrared Fluorescent Silicate Nanosheets(Open Access) Selvaggio G, Weitzel M, (...), Kruss SChemRxiv2021
Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography(Open Access) Eckermann M, van der Meer F, (...), Salditt TBiomedical Optics Express2021
Alpha-Synuclein Antibody Characterization: Why Semantics Matters(Open Access) Outeiro TFMolecular Neurobiology2021
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutationsFomin A, Gärtner A, (...), Linke WAScience Translational Medicine2021
Understanding and treating paediatric hearing impairment(Open Access) Wrobel C, Zafeiriou M, Moser TEBioMedicine2021
Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survivalZelarayan L, Vendrell V, (...), Schimmang TDevelopmental Dynamics2021
Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast InteractionsZimmermann WCirculation Research2021
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels(Open Access) Eisenberg-Bord M, Zung N, (...), Schuldiner MJournal of Cell Biology2021
The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels(Open Access) Brüser C, Keller-Findeisen J, Jakobs SCell Reports2021
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes(Open Access) Michurina A, Sakib MS, (...), Fischer AEMBO Journal2021
Free-Breathing Myocardial T1 Mapping using Inversion-Recovery Radial FLASH and Motion-Resolved Model-Based Reconstruction(Open Access) Wang X, Rosenzweig S, (...), Uecker MarXiv2021
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir(Open Access) Kokic G, Hillen HS, (...), Cramer PNature Communications2021
Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography(Open Access) Eckermann M, Schmitzer B, (...), Salditt TProceedings of the National Academy of Sciences of the United States of America2021
Aneuploidy in human eggs: contributions of the meiotic spindle(Open Access) Thomas C, Cavazza T, Schuh MBiochemical Society Transactions2021
Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2 Interaction in Constrained GeometriesDietz J, Oelkers M, (...), Janshoff ANano Letters2021
Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States(Open Access) Neher E, Taschenberger HNeuroscience2021
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R(Open Access) Dankovich TM, Kaushik R, (...), Rizzoli SONature Communications2021
Towards correlative imaging of neuronal tissue by phase-contrast x-ray tomography and SEM(Open Access) Eckermann M, Ruhwedel T, Möbius W, Salditt TDevelopments in X-Ray Tomography XIII2021
Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy(Open Access) Perego E, Köster SLab on a Chip2021
Minimax detection of localized signals in statistical inverse problems(Open Access) Pohlmann M, Werner F, Munk AarXiv2021
Trans-synaptic assemblies link synaptic vesicles and neuroreceptors(Open Access) Martinez-Sanchez A, Laugks U, (...), Lučić VScience Advances2021
Epigenetic gene expression links heart failure to memory impairment(Open Access) Islam MR, Lbik D, (...), Fischer AEMBO Molecular Medicine2021
Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms(Open Access) Heinemann F, Klatt M, Munk AarXiv2021
Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis(Open Access) Hofemeier AD, Limón T, (...), Betz TElife2021
Electronic laboratory notekeeping at the Göttingen Campus(Open Access) Kusch HZenodo2021
Phase Separation during Germline Development(Open Access) So C, Cheng S, Schuh MTrends in Cell Biology2021
Super-resolution imaging: when biophysics meets nanophotonics(Open Access) Koenderink AF, Tsukanov R, Enderlein J, Izeddin I, Krachmalnicoff VNanophotonics2021
Regulation of a subset of release-ready vesicles by the presynaptic protein Mover(Open Access) Pofantis E, Neher E, Dresbach TProceedings of the National Academy of Sciences of the United States of America2021
Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells(Open Access) Vasili E, Dominguez-Meijide A, (...), Outeiro TResearchsquare2021
NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover(Open Access) Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SOBMC Molecular and Cell Biology2021
Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors(Open Access) Nadler F, Lavdovskaia E, Richter-Dennerlein RRNA Biology2021
Free-Breathing Water, Fat, R⋆2 and B0 Field Mapping of the Liver Using Multi-Echo Radial FLASH and Regularized Model-based Reconstruction (MERLOT)(Open Access) Tan Z, Rosenzweig S, (...), Uecker MarXiv2021
Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer(Open Access) Thiele JC, Jungblut M, (...), Enderlein JbioRxiv2021
Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness(Open Access) Rankovic V, Vogl C, (...), Moser TFrontiers in Molecular Neuroscience2021
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity(Open Access) Riera-Tur I, Schäfer T, (...), Dudanova ILife Science Alliance2021
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea(Open Access) Hua Y, Ding X, (...), Wu HCell Reports2021
Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer ImagingRaja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh ANano Letters2021
Role of GTPases in Driving Mitoribosome AssemblyMaiti P, Lavdovskaia E, Barrientos A, Richter-Dennerlein RTrends in Cell Biology2021
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis(Open Access) Kabinger F, Stiller C, (...), Cramer PNature Structural & Molecular Biology2021
RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse(Open Access) Butola T, Alvanos T, (...), Moser TJournal of Neuroscience2021
Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors(Open Access) Dennerlein S, Poerschke S, (...), Rehling PeLife2021
Molecular and functional architecture of striatal dopamine release sitesBanerjee A, Imig C, (...), Kaeser PSNeuron2021
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study(Open Access) Tampe D, Hakroush S, (...), Tampe BFrontiers in Medicine2021
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion(Open Access) Grabner CP, Moser TeLife2021
Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis(Open Access) Barbarics B, Eildermann K, (...), Bohnenberger HScientific Reports2021
3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography(Open Access) Reichardt M, Moller Jensen P, (...), Salditt TeLife2021
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomogramsMoebel E, Martinez-Sanchez A, (...), Kervrann CNature Methods2021
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery(Open Access) Walter C, Marada A, (...), Meisinger CNature Communications2021
Towards Visual Proteomics at High Resolution(Open Access) Bäuerlein FJ, Baumeister WJournal of Molecular Biology2021
Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission(Open Access) Lipstein N, Chang S, (...), Brose NNeuron2021
Allosteric control of Ubp6 and the proteasome via a bidirectional switch(Open Access) Hung KYS, Klumpe S, (...), Finley DbioRxiv2021
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Structures and implications of TBP–nucleosome complexes(Open Access) Wang H, Xiong L, Cramer PProceedings of the National Academy of Sciences of the United States of America2021
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Advanced Data Analysis for Fluorescence-Lifetime Single-Molecule Localization Microscopy(Open Access) Thiele JC, Nevskyi O, Helmerich DA, Sauer M, Enderlein JFrontiers in Bioinformatics2021
Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator(Open Access) Perera RP, Shaikhqasem A, (...), Dosch RBiomolecules2021
Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner(Open Access) Sokpor G, Kerimoglu C, (...), Tuoc TFrontiers in Molecular Neuroscience2021
Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain(Open Access) Abbas E, Hassan MA, (...), Tuoc TFrontiers in Cell and Developmental Biology2021
Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus(Open Access) Akol I, Heidrich S, (...), Vogel TbioRxiv2021
A microRNA signature that correlates with cognition and is a target against cognitive decline(Open Access) Islam MR, Kaurani L, (...), Fischer AEMBO Molecular Medicine2021
Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity(Open Access) Shahriyari M, Islam MR, (...), Tiburcy MbioRxiv2021
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders(Open Access) Klemp HG, Kettwig M, Streit F, Gärtner J, Rosewich H, Krätzner RMetabolites2021
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics(Open Access) Beckert B, Leroy EC, (...), Wilson DNNature Communications2021
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Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model(Open Access) Oestreicher D, Picher MM, Rankovic V, Moser T, Pangrsic TFrontiers in Molecular Neuroscience2021
Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation(Open Access) Popova B, Wang D, (...), Braus GHFrontiers in Molecular Neuroscience2021
Small Molecule Fisetin Modulates Alpha–Synuclein Aggregation(Open Access) Rosado-Ramos R, Godinho-Pereira J, (...), Nunes dos Santos CMolecules2021
Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease(Open Access) Oliveira LMA, Gasser T, (...), Outeiro TFnpj Parkinsons Disease2021
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation(Open Access) Torres-Garcia L, Domingues JM, (...), Li JResearchsquare2021
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Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies(Open Access) Cappello S, Sung H, (...), Bogeski ICancer Research2021
Impaired Exercise Tolerance in Repaired Tetralogy of Fallot Is Associated With Impaired Biventricular Contractile Reserve: An Exercise-Stress Real-Time Cardiovascular Magnetic Resonance Study(Open Access) Steinmetz M, Stümpfig T, (...), Paul TCirculation-Cardiovascular Imaging2021
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Genomic basis of syndromic short stature in an Algerian patient cohortMoosa S, Chentli F, (...), Wollnik BAmerican Journal of Medical Genetics Part A2021
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures(Open Access) Gönenc II, Wolff A, (...), Wollnik BbioRxiv2021
Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering(Open Access) Raad FS, Khan TA, (...), Zimmermann WChemMedChem2021
Cell programming to protect the ischemic heart and limb(Open Access) Brittan M, Zimmermann WMolecular Therapy2021
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation(Open Access) Schoger E, Zimmermann W, Cyganek L, Zelarayán LCStem Cell Research2021
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Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review(Open Access) Müllenbroich MC, Kelly A, (...), Smith GLFrontiers in Physiology2021
The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool(Open Access) Wegener JW, Wagdi A, (...), Lehnart SEFrontiers in Physiology2021
Survey of germline variants in cancer‐associated genes in young adults with colorectal cancerMikaeel RR, Young JP, (...), Price TJGenes Chromosomes and Cancer2021
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Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes(Open Access) Peper J, Kownatzki-Danger D, (...), Lehnart SECirculation Research2021
Transcriptionally active enhancers in human cancer cells(Open Access) Lidschreiber K, Jung LA, (...), Lidschreiber MMolecular Systems Biology2021
Combined scanning small-angle X-ray scattering and holography probes multiple length scales in cell nuclei(Open Access) Wittmeier A, Cassini C, (...), Köster SJournal of Synchrotron Radiation2021
Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy(Open Access) Reinert M, Pacheu-Grau D, (...), Brockmann KOrphanet Journal of Rare Diseases2021
Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast(Open Access) Zhang Y, De Laurentiis E, (...), Rospert SNature Communications2021
Stress-induced nuclear condensation of NELF drives transcriptional downregulation(Open Access) Rawat P, Boehning M, (...), Sawarkar RMolecular Cell2021
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells(Open Access) Tegunov D, Xue L, Dienemann C, Cramer P, Mahamid JNature Methods2021
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo(Open Access) Dominguez-Meijide A, Parrales V, (...), Outeiro TFNeurobiology of Disease2021
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Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers(Open Access) Zhang Y, Dijkman PM, (...), Kudryashev MNature Communications2021
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New Species Can Broaden Myelin Research: Suitability of Little Skate, Leucoraja erinacea(Open Access) Möbius W, Hümmert S, Ruhwedel T, Kuzirian A, Gould RLife2021
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Transcription activation depends on the length of the RNA polymerase II C‐terminal domain(Open Access) Sawicka A, Villamil G, (...), Cramer PEMBO Journal2021
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Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels(Open Access) Cheret C, Ganzella M, Preobraschenski J, Jahn R, Ahnert-Hilger GCell Reports2021
Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies(Open Access) Brás IC, Outeiro TFCells2021
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Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy(Open Access) Oliveira da Silva MI, Santejo M, (...), Liz MbioRxiv2021
RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses(Open Access) Krinner S, Predoehl F, Burfeind D, Vogl C, Moser TFrontiers in Molecular Neuroscience2021
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term(Open Access) Reshetniak S, Rizzoli SOCurrent Opinion in Cell Biology2021
Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm controlHoffmann S, Schmitteckert S, (...), Rappold GBiochimica et Biophysica Acta-Gene Regulatory Mechanisms2021
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Colocalization for super-resolution microscopy via optimal transport(Open Access) Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk ANature Computational Science2021
Origins and mechanisms leading to aneuploidy in human eggs(Open Access) Wartosch L, Schindler K, (...), Xing JPrenatal Diagnosis2021
Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers(Open Access) Yudovich S, Marzouqe A, (...), Weiss SbioRxiv2021
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Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications(Open Access) Vanegas LJ, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk AarXiv2021
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex(Open Access) Ulmke PA, Sakib MS, (...), Tuoc TStem Cell Reports2021
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The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs(Open Access) Hillen HS, Markov DA, (...), Anikin MProceedings of the National Academy of Sciences of the United States of America2021
The structure of Prp2 bound to RNA and ADP-BeF3− reveals structural features important for RNA unwinding by DEAH-box ATPases(Open Access) Hamann F, Zimmerningkat LC, (...), Ficner RActa Crystallographica Section D-Structural Biology2021
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding(Open Access) Bartsch A, Ives CM, (...), Llabrés SBiochimica et Biophysica Acta-Biomembranes2021
Multiscale photonic imaging of the native and implanted cochlea(Open Access) Keppeler D, Kampshoff CA, (...), Moser TProceedings of the National Academy of Sciences of the United States of America2021
The Cdk8 kinase module regulates interaction of the Mediator complex with RNA polymerase II(Open Access) Osman S, Mohammad E, (...), Cramer PJournal of Biological Chemistry2021
Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo(Open Access) Albert K, Raymundo DP, (...), Airavaara MMolecular Therapy2021
Parental genome unification is highly error-prone in mammalian embryos(Open Access) Cavazza T, Takeda Y, (...), Schuh MCell2021
Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway(Open Access) Bali B, Lopez de la Morena D, (...), Moser TEMBO Molecular Medicine2021
Tissue engineered heart repair from preclinical models to first-in-patient studiesZimmermann WCurrent Opinion in Physiology2020
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea(Open Access) Hua Y, Ding X, (...), Wu HbioRxiv2020
Epigenetic gene-expression links heart failure to memory impairment(Open Access) Islam R, Lbik D, (...), Fischer AbioRxiv2020
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Structure of the transcription coactivator SAGAWang H, Dienemann C, Stützer A, Urlaub H, Cheung ACM, Cramer PNature2020
Molecular signature of slowly expanding lesions in progressive multiple sclerosis(Open Access) Jäckle K, Zeis T, (...), Brück WBrain2020
Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative NanoscopyStaudt T, Aspelmeier T, Laitenberger O, Geisler C, Egner A, Munk AStatistical Science2020
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles(Open Access) Grabner CP, Moser TbioRxiv2020
Stress- and ubiquitylation-dependent phase separation of the proteasomeYasuda S, Tsuchiya H, (...), Saeki YNature2020
Molecular and functional architecture of striatal dopamine release sites(Open Access) Banerjee A, Imig C, (...), Kaeser PSbioRxiv2020
Choice of fluorophore affects dynamic DNA nanostructures(Open Access) Jahnke K, Grubmüller H, Igaev M, Göpfrich KbioRxiv2020
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing(Open Access) Oberbeckmann E, Niebauer V, (...), Korber PbioRxiv2020
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses(Open Access) Maus L, Lee C, (...), Cooper BHCell Reports2020
Emerging approaches for restoration of hearing and vision(Open Access) Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser TPhysiological Reviews2020
Kinetics of Loop Closure in Disordered Proteins: Theory vs Simulations vs ExperimentsSatija R, Das A, Mühle S, Enderlein J, Makarov DEJournal of Physical Chemistry B2020
Wide-Field Fluorescence Lifetime Imaging of Single MoleculesOleksiievets N, Thiele JC, (...), Enderlein JJournal of Physical Chemistry A2020
A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19(Open Access) Islam MR, Fischer Apreprints.org2020
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor functionDodonova SO, Zhu F, Dienemann C, Taipale J, Cramer PNature2020
Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice(Open Access) Zheng X, Zhang L, (...), Doeppner TRTranslational Stroke Research2020
What is resolution? A statistical minimax testing perspective on super-resolution microscopy(Open Access) Kulaitis G, Munk A, Werner FarXiv2020
Structure of replicating SARS-CoV-2 polymerase(Open Access) Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov D, Cramer PNature2020
Elemental quantification and analysis of structural abnormalities in neurons from Parkinson’s-diseased brains by X-ray fluorescence microscopy and diffraction(Open Access) Joppe K, Nicolas J, Grünewald TA, Eckermann M, Salditt T, Lingor PBiomedical Optics Express2020
A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome(Open Access) Drivas TG, Li D, (...), Bhoj EEuropean Journal of Human Genetics2020
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory responseStik G, Vidal E, (...), Graf TNature Genetics2020
Large field-of-view scanning small-angle X-ray scattering of mammalian cells(Open Access) Cassini C, Wittmeier A, Brehm G, Denz M, Burghammer M, Köster SJournal of Synchrotron Radiation2020
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activationVos SM, Farnung L, Linden A, Urlaub H, Cramer PNature Structural & Molecular Biology2020
Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis(Open Access) Backhaus SJ, Lange T, (...), Schuster AJournal of Cardiovascular Magnetic Resonance2020
MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation(Open Access) Stephan T, Brüser C, (...), Jakobs SEMBO Journal2020
μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve(Open Access) Dieter A, Klein E, (...), Moser TEMBO Molecular Medicine2020
The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27(Open Access) Lemus-Diaz N, Ferreira RR, Bohnsack KE, Gruber J, Bohnsack MTNucleic Acids Research2020
A comparative analysis of the mobility of 45 proteins in the synaptic bouton(Open Access) Reshetniak S, Ußling J, (...), Rizzoli SOEMBO Journal2020
The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders(Open Access) Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle Bpreprints.org2020
Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope ArchitectureChizhik AI, Chizhik AM, (...), Enderlein JMethods in Molecular Biology2020
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodentsKeppeler D, Schwaerzle M, (...), Moser TScience Translational Medicine2020
Remyelination in multiple sclerosis: from basic science to clinical translationLubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff BLancet Neurology2020
Reliable estimation of membrane curvature for cryo-electron tomography(Open Access) Salfer M, Collado JF, Baumeister W, Fernández-Busnadiego R, Martínez-Sánchez APLOS Computational Biology2020
CG-SENSE revisited: Results from the first ISMRM reproducibility challenge(Open Access) Maier O, Baete SH, (...), Knoll FarXiv2020
Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins(Open Access) Pape JK, Stephan T, (...), Hell SWProceedings of the National Academy of Sciences of the United States of America2020
The mRNA-Binding Protein RBM3 Regulates Activity Patterns and Local Synaptic Translation in Cultured Hippocampal Neurons(Open Access) Sertel SM, von Elling-Tammen MS, Rizzoli SOJournal of Neuroscience2020
Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control(Open Access) Hu Y, Korovaichuk A, (...), Bringmann HGenetics2020
Heterogeneous Idealization of Ion Channel Recordings - Open Channel Noise(Open Access) Pein F, Bartsch A, Steinem C, Munk AarXiv2020
Dopamine promotes the neurodegenerative potential of β‐synuclein(Open Access) Raina A, Leite K, (...), Kügler SJournal of Neurochemistry2020
Rosalind Franklin and the Advent of Molecular Biology(Open Access) Cramer PCell2020
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids(Open Access) Zafeiriou M, Bao G, (...), Zimmermann WNature Communications2020
Structural Biology of RNA Polymerase II Transcription: 20 Years OnOsman S, Cramer PAnnual Review of Cell and Developmental Biology2020
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholambanMenzel J, Kownatzki-Danger D, (...), Schwappach BScience Signaling2020
Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex(Open Access) Heimes M, Fiorentino F, (...), Sinning IMolecular Cell2020
3D analysis of the myenteric plexus of the human bowel by X-ray phase-contrast tomography – a future method?(Open Access) Peruzzi N, Veress B, (...), Ohlsson BScandinavian Journal of Gastroenterology2020
Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells(Open Access) Bäuerlein FJ, Fernández-Busnadiego R, Baumeister WTrends in Cell Biology2020
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices(Open Access) Imig C, López-Murcia FJ, (...), Cooper BHNeuron2020
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity(Open Access) Cantuti-Castelvetri L, Ojha R, (...), Simons MScience2020
MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis(Open Access) Wildemann B, Jarius S, Franz J, Ruprecht K, Reindl M, Stadelmann CActa Neuropathologica2020
Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries(Open Access) Kovacs S, Li H, Haubner L, Munk A, Bühlmann ParXiv2020
Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software(Open Access) Pein F, Eltzner B, Munk ACRAN2020
Quantitative analysis of hidden particles diffusing behind a scattering layer using speckle correlation(Open Access) Sarkar A, Wang I, Enderlein J, Derouard J, Delon AOptics Express2020
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxideMontiel V, Bella R, (...), Balligand JScience Translational Medicine2020
Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy(Open Access) Thiele JC, Helmerich DA, (...), Enderlein JACS Nano2020
Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia(Open Access) Schröder S, Li Y, (...), Brockmann KGenetics in Medicine2020
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson’s disease patients(Open Access) Hentrich T, Wassouf Z, (...), Schulze-Hentrich JMAging-US2020
3d phase‐contrast nanotomography of unstained human skin biopsies may identify morphological differences in the dermis and epidermis between subjects(Open Access) Eckermann M, Peruzzi N, (...), Ohlsson BSkin Research and Technology2020
Physics-based Reconstruction Methods for Magnetic Resonance Imaging(Open Access) Wang X, Tan Z, Scholand N, Roeloffs V, Uecker MarXiv2020
Variational multiscale nonparametric regression: Algorithms(Open Access) del Alamo M, Li H, Munk A, Werner FarXiv2020
3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography(Open Access) Frohn J, Pinkert-Leetsch D, (...), Salditt TJournal of Synchrotron Radiation2020
Defining the architecture of the human TIM22 complex by chemical crosslinking(Open Access) Valpadashi A, Callegari S, (...), Rehling PFEBS Letters2020
Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity(Open Access) Ruhlandt D, Andresen M, (...), Chizhik AICommunications Biology2020
Engineered Heart Muscle Models in Phenotypic Drug ScreensZimmermann WHandb Exp Pharmacol2020
Pharmacological Modulators of Tau Aggregation and Spreading(Open Access) Dominguez-Meijide A, Vasili E, Outeiro TFBrain Sciences2020
Variational Multiscale Nonparametric Regression: Algorithms and Implementation(Open Access) del Alamo M, Li H, Munk A, Werner FAlgorithms2020
Viral rhodopsins 1 are an unique family of light-gated cation channels(Open Access) Zabelskii D, Alekseev A, (...), Gordeliy VNature Communications2020
From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease(Open Access) Outeiro TF, Heutink P, Bezard E, Cenci AMMovement Disorders2020
Efficient modeling of three-dimensional convection–diffusion problems in stationary flows(Open Access) Thiele JC, Gregor I, Karedla N, Enderlein JPhysics of Fluids2020
Ion type and valency differentially drive vimentin tetramers into intermediate filaments or higher order assemblies(Open Access) Denz M, Marschall M, Herrmann H, Köster SSoft Matter2020
Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy(Open Access) Hanses U, Kleinsorge M, (...), Cyganek LCirculation2020
Doubling the resolution of a confocal spinning-disk microscope using image scanning microscopyQin S, Isbaner S, Gregor I, Enderlein JNature Protocols2020
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19(Open Access) Meinhardt J, Radke J, (...), Heppner FLNature Neuroscience2020
A minimalist model to measure interactions between proteins and synaptic vesicles(Open Access) Perego E, Reshetniak S, (...), Köster SScientific Reports2020
The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin(Open Access) Seefelder M, Alva V, (...), Kochanek SBMC Evolutionary Biology2020
Alpha‐synuclein oligomerization and aggregation: a model will always be a model(Open Access) Outeiro TFJournal of Neurochemistry2020
[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates(Open Access) Kuebler L, Buss S, (...), Herfert KEuropean Journal of Nuclear Medicine and Molecular Imaging2020
X-ray diffraction and second harmonic imaging reveal new insights into structural alterations caused by pressure-overload in murine hearts(Open Access) Nicolas J, Khan A, (...), Salditt TScientific Reports2020
A sensory cell diversifies its output by varying Ca2+ influx‐release coupling among active zones(Open Access) Özcete ÖD, Moser TEMBO Journal2020
Cancer and Parkinson's Disease: Common Targets, Emerging HopesFilippou PS, Outeiro TFMovement Disorders2020
Small-molecule inhibitors of human mitochondrial DNA transcription(Open Access) Bonekamp NA, Peter B, (...), Larsson NNature2020
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samplesParfentev I, Schilbach S, Cramer P, Urlaub HJournal of Proteomics2020
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol(Open Access) Gerdes C, Waal N, (...), Opazo FNature Communications2020
Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination(Open Access) Lohrberg M, Winkler A, (...), Barrantes-Freer AActa Neuropathologica Communications2020
Integrator is a genome-wide attenuator of non-productive transcriptionLykke-Andersen S, Žumer K, (...), Jensen THMolecular Cell2020
Macromolecular and electrical coupling between inner hair cells in the rodent cochlea(Open Access) Jean P, Anttonen T, (...), Moser TNature Communications2020
Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesSeibertz F, Reynolds M, Voigt NJournal of Visualized Experiments2020
Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells(Open Access) Effertz T, Moser T, Oliver DFaculty Reviews2020
Molecular and cellular dynamics of the 26S proteasome(Open Access) Sakata E, Eisele MR, Baumeister WBiochimica et Biophysica Acta-Proteins and Proteomics2020
Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐based Exchangeable Fluorophores(Open Access) Glogger M, Spahn C, Enderlein J, Heilemann MAngewandte Chemie-International Edition2020
Post-translational modifications soften vimentin intermediate filaments(Open Access) Kraxner J, Lorenz C, (...), Köster SNanoscale2020
Aplasia cutis congenita in a CDC42‐related developmental phenotypeSchnabel F, Kamphausen SB, Funke R, Kaulfuß S, Wollnik B, Zenker MAmerican Journal of Medical Genetics Part A2020
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes(Open Access) Lavdovskaia E, Denks K, (...), Richter-Dennerlein RNucleic Acids Research2020
Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees(Open Access) Heinemann F, Munk A, Zemel YarXiv2020
Structural basis of nucleosome transcription mediated by Chd1 and FACT(Open Access) Farnung L, Ochmann M, Engeholm M, Cramer PbioRxiv2020
Cellular and mitochondrial mechanisms of atrial fibrillation(Open Access) Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt NBasic Research in Cardiology2020
The Coding And Small-Non-Coding Hippocampal Synaptic RNAome(Open Access) Epple R, Krüger D, (...), Fischer AbioRxiv2020
Drosophila Mechanosensory TransductionHehlert P, Zhang W, Göpfert MCTrends in Neurosciences2020
Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity(Open Access) Medina L, González-Lizárraga F, (...), Socias SBbioRxiv2020
CG‐SENSE revisited: Results from the first ISMRM reproducibility challenge(Open Access) Maier O, Baete SH, (...), Knoll FMagnetic Resonance in Medicine2020
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R(Open Access) Dankovich TM, Kaushik R, (...), Rizzoli SObioRxiv2020
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2(Open Access) Kreutzberger AJ, Kiessling V, (...), Tamm LKeLife2020
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo(Open Access) Dominguez-Meijide A, Parrales V, (...), Outeiro TFbioRxiv2020
Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes(Open Access) Dijkman PM, Muñoz-García JC, (...), Watts AScience Advances2020
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding(Open Access) Bartsch A, Ives C, (...), Llabrés SbioRxiv2020