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| From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms |
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| New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain |
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| Editorial: Cardiac optogenetics: Using light to observe and excite the heart |
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| Cotranslational Biogenesis of Membrane Proteins in Bacteria |
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| On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants |
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| The Role of Junctophilin Proteins in Cellular Function |
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| On the Uniqueness of Kantorovich Potentials |
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| A Molecular Pump Facilitates Mechanical Adsorption Away from Equilibrium | | Simeth NA | Angewandte Chemie-International Edition | 2022 | | |
| Dystrophin is a mechanical tension modulator |
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| Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria |
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| Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses |
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| Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells |
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| The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds |
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| Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation |
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| Deep, Deep Learning with BART |
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| A Unifying Approach to Distributional Limits for Empirical Optimal Transport |
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| White matter integrity in mice requires continuous myelin synthesis at the inner tongue |
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| MemBrain: A Deep Learning-aided Pipeline for Automated Detection of Membrane Proteins in Cryo-electron Tomograms |
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| A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease |
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| Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition |
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| Extracellular alpha-synuclein: Sensors, receptors, and responses |
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| Roles and dynamics of 3-methylcytidine in cellular RNAs |
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| Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system |
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| Statistical analysis of random objects via metric measure Laplacians |
| Mordant G, Munk A | arXiv | 2022 | | |
| Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration |
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| The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible |
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| Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance |
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| Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice |
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| IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress |
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| Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea |
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| Excited state lifetime modulation in semiconductor nanocrystals for super-resolution imaging |
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| Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair | | Tiburcy M, Meyer T, Satin P, Zimmermann W | Methods in Molecular Biology | 2022 | | |
| A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution | | Elizarova S, Chouaib AA, (...), Daniel JA | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
| Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
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| Background calcium influx in arrhythmia: lead actor or extra? |
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| Not the classical serendipity: does doxapram treat atrial fibrillation? |
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| Retinal receptive-field substructure: scaffolding for coding and computation |
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| Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome |
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| An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry |
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| Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
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| Isotropic three-dimensional dual-color super-resolution microscopy with metal-induced energy transfer |
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| Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells |
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| Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations |
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| α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease |
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| Transmembrane β‐peptide helices as molecular rulers at the membrane surface |
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| Structural basis of nucleosome transcription mediated by Chd1 and FACT |
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| Radiative Rate Modulation Reveals Near‐Unity Quantum Yield of Graphene Quantum Dots |
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| Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis |
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| Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases |
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| Analysis of patchclamp recordings: model-free multiscale methods and software |
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| Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome |
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| In situ architecture of neuronal α-Synuclein inclusions |
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| Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
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| IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter |
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| Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology |
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| Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy | | Xu H, Wali R, (...), Ebert A | FEBS Letters | 2021 | | |
| MINSTED fluorescence localization and nanoscopy |
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| Astrocytes control the spiking of mouse visual cortex layer 5 pyramidal neurons |
| Sundaram SM, Garg P, Leßlich HM, Mathivanan S | Journal of Physiology-London | 2021 | | |
| Multiple haplotype reconstruction from allele frequency data | | Pelizzola M, Behr M, Li H, Munk A, Futschik A | Nature Computational Science | 2021 | | |
| Physics-based reconstruction methods for magnetic resonance imaging |
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| Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons |
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| Sequence determinants of human gene regulatory elements |
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| RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse |
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| Dimeric form of SARS-CoV-2 polymerase |
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| A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites |
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| Cryo-electron tomography of native Drosophila tissues vitrified by plunge freezing |
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| Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
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| Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain |
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| Instant three color multi-plane fluorescence microscopy |
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| Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea |
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| Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy |
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| Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
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| A DNA-based optical force sensor for live-cell applications | | Jayachandran C, Ghosh A, (...), Schmidt CF | bioRxiv | 2021 | | |
| Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci |
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| Exercise Stress Real-Time Cardiac Magnetic Resonance Imaging for Noninvasive Characterization of Heart Failure With Preserved Ejection Fraction |
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| Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity |
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| MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile |
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| Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants |
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| Posterior analysis of n in the binomial (n,p) problem with both parameters unknown -- with applications to quantitative nanoscopy |
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| The ultrametric Gromov-Wasserstein distance |
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| Frame-constrained total variation regularization for white noise regression |
| del Álamo M, Li H, Munk A | Annals of Statistics | 2021 | | |
| The Statistics of Circular Optimal Transport |
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| Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 | | Gregor C | bioRxiv | 2021 | | |
| Limit Distributions and Sensitivity Analysis for Entropic Optimal Transport on Countable Spaces |
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| Transport Dependency: Optimal Transport Based Dependency Measures |
| Nies TG, Staudt T, Munk A | arXiv | 2021 | | |
| Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state |
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| Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein |
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| Posterior analysis of n in the binomial (n,p) problem with both parameters unknown—with applications to quantitative nanoscopy |
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| Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils |
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| Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling |
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| What is resolution? A statistical minimax testing perspective on superresolution microscopy |
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| Photophysical properties and fluorescence lifetime imaging of exfoliated near-infrared fluorescent silicate nanosheets |
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| CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation |
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| Allosteric transcription stimulation by RNA polymerase II super elongation complex | | Chen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer P | Molecular Cell | 2021 | | |
| Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells |
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| Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors |
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| MFSD2A-associated primary microcephaly - Expanding the clinical and mutational spectrum of this ultra-rare disease | | Khuller K, Yigit G, (...), Kuechler A | European Journal of Medical Genetics | 2021 | | |
| Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging |
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| Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression |
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| The structure of a dimeric form of SARS-CoV-2 polymerase |
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| Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo |
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| Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons |
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| Structural basis of RNA processing by human mitochondrial RNase P |
| Bhatta A, Dienemann C, Cramer P, Hillen HS | Nature Structural & Molecular Biology | 2021 | | |
| Fibroblast Derived Human Engineered Connective Tissue for Screening Applications | | Santos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz S | Journal of Visualized Experiments | 2021 | | |
| Structure of an inactive RNA polymerase II dimer |
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| Structural basis of human transcription–DNA repair coupling |
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| Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy |
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| Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration |
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| Management of Metadata Types in Basic Cardiological Research |
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| The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1 |
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| Biallelic variants in YRDC cause a developmental disorder with progeroid features |
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| Mapping protein interactions in the active TOM-TIM23 supercomplex |
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| Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501 |
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| Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis |
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| Familial cleft tongue caused by a unique translation initiation codon variant in TP63 |
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| Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy |
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| An in vitro system to silence mitochondrial gene expression |
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| A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease |
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| Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy |
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| Instant three-color multiplane fluorescence microscopy |
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| Structural basis of Integrator-mediated transcription regulation | | Fianu I, Chen Y, (...), Cramer P | Science | 2021 | | |
| Effects of cryo-EM cooling on structural ensembles |
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| Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy |
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| Exfoliation and Optical Properties of Near-Infrared Fluorescent Silicate Nanosheets |
| Selvaggio G, Weitzel M, (...), Kruss S | ChemRxiv | 2021 | | |
| Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography |
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| Alpha-Synuclein Antibody Characterization: Why Semantics Matters |
| Outeiro TF | Molecular Neurobiology | 2021 | | |
| Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations | | Fomin A, Gärtner A, (...), Linke WA | Science Translational Medicine | 2021 | | |
| Understanding and treating paediatric hearing impairment |
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| Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast Interactions | | Zimmermann W | Circulation Research | 2021 | | |
| Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels |
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| The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels |
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| Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes |
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| Free-Breathing Myocardial T1 Mapping using Inversion-Recovery Radial FLASH and Motion-Resolved Model-Based Reconstruction |
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| Mechanism of SARS-CoV-2 polymerase stalling by remdesivir |
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| Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography |
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| Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States |
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| Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
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| Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy |
| Perego E, Köster S | Lab on a Chip | 2021 | | |
| Minimax detection of localized signals in statistical inverse problems |
| Pohlmann M, Werner F, Munk A | arXiv | 2021 | | |
| Epigenetic gene expression links heart failure to memory impairment |
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| Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms |
| Heinemann F, Klatt M, Munk A | arXiv | 2021 | | |
| Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis |
| Hofemeier AD, Limón T, (...), Betz T | Elife | 2021 | | |
| Electronic laboratory notekeeping at the Göttingen Campus |
| Kusch H | Zenodo | 2021 | | |
| Phase Separation during Germline Development |
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| Super-resolution imaging: when biophysics meets nanophotonics |
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| Regulation of a subset of release-ready vesicles by the presynaptic protein Mover |
| Pofantis E, Neher E, Dresbach T | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
| Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells |
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| NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover |
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| Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors |
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| Free-Breathing Water, Fat, R⋆2 and B0 Field Mapping of the Liver Using Multi-Echo Radial FLASH and Regularized Model-based Reconstruction (MERLOT) |
| Tan Z, Rosenzweig S, (...), Uecker M | arXiv | 2021 | | |
| Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer |
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| Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness |
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| Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity |
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| Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea |
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| Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis |
| Kabinger F, Stiller C, (...), Cramer P | Nature Structural & Molecular Biology | 2021 | | |
| RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse |
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| Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study |
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| The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion |
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| Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis |
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| Towards Visual Proteomics at High Resolution |
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| Structures and implications of TBP–nucleosome complexes |
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| Advanced Data Analysis for Fluorescence-Lifetime Single-Molecule Localization Microscopy |
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| Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator |
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| A microRNA signature that correlates with cognition and is a target against cognitive decline |
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| A mathematical model for electrical activity in pig atrial tissue |
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| Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model |
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| Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation |
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| Small Molecule Fisetin Modulates Alpha–Synuclein Aggregation |
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| Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease |
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| Ectosomes and exosomes are distinct proteomic entities that modulate spontaneous activity in neuronal cells |
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| Molecular bases of mitochondrial disorders |
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| Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies |
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| Impaired Exercise Tolerance in Repaired Tetralogy of Fallot Is Associated With Impaired Biventricular Contractile Reserve: An Exercise-Stress Real-Time Cardiovascular Magnetic Resonance Study |
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| 0753 Free-Breathing Liver Fat and R2* Mapping: Multi-Echo Radial FLASH and Model-based Reconstruction (MERLOT) |
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| Genomic basis of syndromic short stature in an Algerian patient cohort | | Moosa S, Chentli F, (...), Wollnik B | American Journal of Medical Genetics Part A | 2021 | | |
| Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures |
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| Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering |
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| Cell programming to protect the ischemic heart and limb |
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| Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation |
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| Author Correction: Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms |
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| Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review |
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| The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool |
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| Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer | | Mikaeel RR, Young JP, (...), Price TJ | Genes Chromosomes and Cancer | 2021 | | |
| Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
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| Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer |
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| Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders |
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| Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes |
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| Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy |
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| The Coding and Small Non-coding Hippocampal Synaptic RNAome |
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| Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels |
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| Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies |
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| Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
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| Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications |
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| Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex |
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| Multiscale photonic imaging of the native and implanted cochlea |
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| The Cdk8 kinase module regulates interaction of the Mediator complex with RNA polymerase II |
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| Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo |
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| Phase-contrast x-ray tomography of neuronal tissue at laboratory sources with submicron resolution |
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| Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease |
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| Multiscale Quantile Segmentation | | Vanegas LJ, Behr M, Munk A | Journal of the American Statistical Association | 2020 | | |
| Structure of the transcription coactivator SAGA | | Wang H, Dienemann C, Stützer A, Urlaub H, Cheung ACM, Cramer P | Nature | 2020 | | |
| Molecular signature of slowly expanding lesions in progressive multiple sclerosis |
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| Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative Nanoscopy | | Staudt T, Aspelmeier T, Laitenberger O, Geisler C, Egner A, Munk A | Statistical Science | 2020 | | |
| The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles |
| Grabner CP, Moser T | bioRxiv | 2020 | | |
| Stress- and ubiquitylation-dependent phase separation of the proteasome | | Yasuda S, Tsuchiya H, (...), Saeki Y | Nature | 2020 | | |
| Molecular and functional architecture of striatal dopamine release sites |
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| Choice of fluorophore affects dynamic DNA nanostructures |
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| Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
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| Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses |
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| Emerging approaches for restoration of hearing and vision |
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| Kinetics of Loop Closure in Disordered Proteins: Theory vs Simulations vs Experiments | | Satija R, Das A, Mühle S, Enderlein J, Makarov DE | Journal of Physical Chemistry B | 2020 | | |
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| A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19 |
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| Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function | | Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P | Nature | 2020 | | |
| Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
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| What is resolution? A statistical minimax testing perspective on super-resolution microscopy |
| Kulaitis G, Munk A, Werner F | arXiv | 2020 | | |
| Structure of replicating SARS-CoV-2 polymerase |
| Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov D, Cramer P | Nature | 2020 | | |
| Elemental quantification and analysis of structural abnormalities in neurons from Parkinson’s-diseased brains by X-ray fluorescence microscopy and diffraction |
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| A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome |
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| CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response | | Stik G, Vidal E, (...), Graf T | Nature Genetics | 2020 | | |
| Large field-of-view scanning small-angle X-ray scattering of mammalian cells |
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| Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis |
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| MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation |
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| μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve |
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| The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27 |
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| A comparative analysis of the mobility of 45 proteins in the synaptic bouton |
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| The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
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| Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents | | Keppeler D, Schwaerzle M, (...), Moser T | Science Translational Medicine | 2020 | | |
| Remyelination in multiple sclerosis: from basic science to clinical translation | | Lubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff B | Lancet Neurology | 2020 | | |
| Reliable estimation of membrane curvature for cryo-electron tomography |
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| CG-SENSE revisited: Results from the first ISMRM reproducibility challenge |
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| Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins |
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| The mRNA-Binding Protein RBM3 Regulates Activity Patterns and Local Synaptic Translation in Cultured Hippocampal Neurons |
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| Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control |
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| Heterogeneous Idealization of Ion Channel Recordings - Open Channel Noise |
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| Dopamine promotes the neurodegenerative potential of β‐synuclein |
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| Rosalind Franklin and the Advent of Molecular Biology |
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| Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids |
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| Structural Biology of RNA Polymerase II Transcription: 20 Years On | | Osman S, Cramer P | Annual Review of Cell and Developmental Biology | 2020 | | |
| 14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban | | Menzel J, Kownatzki-Danger D, (...), Schwappach B | Science Signaling | 2020 | | |
| Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex |
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| 3D analysis of the myenteric plexus of the human bowel by X-ray phase-contrast tomography – a future method? |
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| Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells |
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| Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices |
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| Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity |
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| MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis |
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| Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries |
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| Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software |
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| Quantitative analysis of hidden particles diffusing behind a scattering layer using speckle correlation |
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| Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide | | Montiel V, Bella R, (...), Balligand J | Science Translational Medicine | 2020 | | |
| Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy |
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| Variational multiscale nonparametric regression: Algorithms |
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| 3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography |
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| Variational Multiscale Nonparametric Regression: Algorithms and Implementation |
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| Viral rhodopsins 1 are an unique family of light-gated cation channels |
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| From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease |
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| Efficient modeling of three-dimensional convection–diffusion problems in stationary flows |
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| Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination |
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| Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
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| Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells |
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| Molecular and cellular dynamics of the 26S proteasome |
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| Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐based Exchangeable Fluorophores |
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| Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees |
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| Structural basis of nucleosome transcription mediated by Chd1 and FACT |
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| Cellular and mitochondrial mechanisms of atrial fibrillation |
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| The Coding And Small-Non-Coding Hippocampal Synaptic RNAome |
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| Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity |
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| Heterogeneous Idealization of Ion Channel Recordings – Open Channel Noise |
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| Multiple Haplotype Reconstruction from Allele Frequency Data |
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| Premature aging disorders: A clinical and genetic compendium |
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| Parental genome unification is highly erroneous in mammalian embryos |
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| Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases |
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| In situ architecture of neuronal α-Synuclein inclusions |
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| SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes |
| Michurina A, Sakib S, (...), Fischer A | bioRxiv | 2020 | | |
| RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies |
| Koss DJ, Bondarevaite O, (...), Outeiro TF | Brain Pathology | 2020 | | |
| Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization |
| Dominguez-Meijide A, Vasili E, (...), Outeiro TF | Scientific Reports | 2020 | | |
| Local translation in synaptic mitochondria influences synaptic transmission |
| Yousefi R, Fornasiero EF, (...), Pacheu-Grau D | bioRxiv | 2020 | | |
| Three-dimensional beating dynamics of Chlamydomonas flagella |
| Mojiri S, Isbaner S, (...), Enderlein J | bioRxiv | 2020 | | |
| Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels |
| Bonnin EA, Rizzoli SO | Frontiers in Behavioral Neuroscience | 2020 | | |
| Minimax estimation in linear models with unknown design over finite alphabets |
| Behr M, Munk A | arXiv | 2020 | | |
| Gromov-Wasserstein Distance based Object Matching: Asymptotic Inference |
| Weitkamp CA, Proksch K, Tameling C, Munk A | arXiv | 2020 | | |
| Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations |
| Farnung L, Ochmann M, Cramer P | eLife | 2020 | | |
| Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis |
| Ganapathi M, Argyriou L, (...), Wollnik B | Human Genetics | 2020 | | |
| Fluorescence polarization filtering for accurate single molecule localization |
| Nevskyi O, Tsukanov R, Gregor I, Karedla N, Enderlein J | APL Photonics | 2020 | | |
| Editorial commentary: Challenges to heart repair with pluripotent stem cell-derived cardiomyocytes | | Zimmermann W | Trends in Cardiovascular Medicine | 2020 | | |
| Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.7 Å inside cells |
| Tegunov D, Xue L, Dienemann C, Cramer P, Mahamid J | bioRxiv | 2020 | | |
| Generation of Engineered Human Myocardium in a Multi-well Format |
| Tiburcy M, Meyer T, Liaw NY, Zimmermann W | STAR Protocols | 2020 | | |
| Empirical Regularized Optimal Transport: Statistical Theory and Applications |
| Klatt M, Tameling C, Munk A | SIAM Journal on Mathematics of Data Science | 2020 | | |
| NETT: solving inverse problems with deep neural networks |
| Li H, Schwab J, Antholzer S, Haltmeier M | Inverse Problems | 2020 | | |
| Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system |
| Jablonski L, Harczos T, (...), Moser T | bioRxiv | 2020 | | |
| 19th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products) | | Cavero I, Seimetz D, Koziel D, Zimmermann W, Holzgrefe HH | Expert Opinion on Drug Safety | 2020 | | |
| Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis |
| Puls M, Beuthner BE, (...), Hasenfuß G | European Heart Journal | 2020 | | |
| Tomographic STED microscopy |
| Krüger J, Keller-Findeisen J, Geisler C, Egner A | Biomedical Optics Express | 2020 | | |
| De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome |
| Ufartes R, Berger H, (...), Pauli S | Human Genetics | 2020 | | |
| Circumvention of common labelling artefacts using secondary nanobodies |
| Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F | Nanoscale | 2020 | | |
| Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering |
| Komorowski K, Schaeper J, (...), Salditt T | Soft Matter | 2020 | | |
| Testing for dependence on tree structures |
| Behr M, Ansari MA, Munk A, Holmes C | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
| White matter integrity requires continuous myelin synthesis at the inner tongue |
| Meschkat M, Steyer AM, (...), Möbius W | bioRxiv | 2020 | | |
| A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria |
| Linden A, Deckers M, (...), Urlaub H | Molecular & Cellular Proteomics | 2020 | | |
| Towards the optical cochlear implant: optogenetic approaches for hearing restoration |
| Dieter A, Keppeler D, Moser T | EMBO Molecular Medicine | 2020 | | |
| Human RAD50 deficiency: Confirmation of a distinctive phenotype |
| Ragamin A, Yigit G, (...), Mancini GMS | American Journal of Medical Genetics Part A | 2020 | | |
| Multi-scale X-ray phase-contrast tomography of murine heart tissue |
| Reichardt M, Frohn J, Khan A, Alves F, Salditt T | Biomedical Optics Express | 2020 | | |
| Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome | | Wagner FR, Dienemann C, (...), Cramer P | Nature | 2020 | | |
| Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT |
| Reichardt M, Töpperwien M, Khan A, Alves F, Salditt T | Journal of Medical Imaging | 2020 | | |
| Seeded Binary Segmentation: A general methodology for fast and optimal change point detection |
| Kovács S, Li H, Bühlmann P, Munk A | arXiv | 2020 | | |
| Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control |
| Rathjens FS, Blenkle A, (...), Zafeiriou M | Cardiovascular Research | 2020 | | |
| JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties | | Fonseca-Fonseca LA, da Silva VDA, (...), Núñez-Figueredo Y | Neurotoxicology | 2020 | | |
| Live-cell STED microscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | bioRxiv | 2019 | | |
| Live-cell STED nanoscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | Scientific Reports | 2019 | | |
| Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity | | Schaefer T, Riera-Tur I, (...), Dudanova I | bioRxiv | 2019 | | |
| Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
| Jean P, Anttonen T, (...), Moser T | bioRxiv | 2019 | | |
| The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype |
| Yigit G, Saida K, (...), Altmüller J | Human Mutation | 2019 | | |
| Changes in m6A RNA methylation contribute to heart failure progression by modulating translation | | Berulava T, Buchholz E, (...), Toischer K | European Journal of Heart Failure | 2019 | | |
| Metal-induced energy transfer |
| Gregor I, Chizhik A, Karedla N, Enderlein J | Nanophotonics | 2019 | | |
| MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex |
| Wang C, Richter‐Dennerlein R, (...), Rehling P | EMBO reports | 2019 | | |
| A combined miRNA-piRNA signature to detect Alzheimer's disease |
| Jain G, Stuendl A, (...), Fischer A | Translational Psychiatry | 2019 | | |
| Modeling Fluorescence Correlation Spectroscopy through an aberrating sphere |
| Ruhlandt D, Katti A, Derouard J, Delon A, Enderlein J | arXiv | 2019 | | |
| Empirical optimal transport on countable metric spaces: Distributional limits and statistical applications | | Tameling C, Sommerfeld M, Munk A | Annals of Applied Probability | 2019 | | |
| Circumvention of common labeling artifacts using secondary nanobodies |
| Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F | bioRxiv | 2019 | | |
| The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers |
| Saravanan MS, Ryazanov S, (...), Killian JA | Scientific Reports | 2019 | | |
| Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta | | Moosa S, Yamamoto GL, (...), Netzer C | American Journal of Human Genetics | 2019 | | |
| Graphene-based metal-induced energy transfer for sub-nanometre optical localization | | Ghosh A, Sharma A, (...), Enderlein J | Nature Photonics | 2019 | | |
| Testing for dependence on tree structures |
| Behr M, Ansari MA, Munk A, Holmes C | bioRxiv | 2019 | | |
| Eukaryotic Transcription Turns 50 |
| Cramer P | Cell | 2019 | | |
| Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau |
| Brendel M, Deussing M, (...), Rominger A | Alzheimers Research & Therapy | 2019 | | |
| Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model |
| Wegrzynowicz M, Bar-On D, (...), Spillantini MG | Acta Neuropathologica | 2019 | | |
| Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome |
| Wagner FR, Dienemann C, (...), Cramer P | bioRxiv | 2019 | | |
| Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes |
| Hillen HS, Bartuli J, (...), Cramer P | Cell | 2019 | | |
| Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity |
| Collado J, Kalemanov M, (...), Fernández-Busnadiego R | Developmental Cell | 2019 | | |
| Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes |
| Grimm C, Hillen HS, (...), Fischer U | Cell | 2019 | | |
| Mutation-induced alterations of intra-filament subunit organization in vimentin filaments revealed by SAXS |
| Brennich ME, Vainio U, Wedig T, Bauch S, Herrmann H, Köster S | Soft Matter | 2019 | | |
| A mass spectrometry workflow for measuring protein turnover rates in vivo | | Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF | Nature Protocols | 2019 | | |
| Multiscale quantile segmentation |
| Vanegas LJ, Behr M, Munk A | arXiv | 2019 | | |
| The essential histogram | | Li H, Munk A, Sieling H, Walther G | Biometrika | 2019 | | |
| Loop formation and translational diffusion of intrinsically disordered proteins | | Mühle S, Zhou M, Ghosh A, Enderlein J | Physical Review E | 2019 | | |
| The Essential Histogram |
| Li H, Munk A, Sieling H, Walther G | arXiv | 2019 | | |
| Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding | | Wang H, Farnung L, Dienemann C, Cramer P | Nature Structural & Molecular Biology | 2019 | | |
| 11C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier |
| Maurer A, Leonov A, (...), Griesinger C | ChemMedChem | 2019 | | |
| The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43 |
| Keihani S, Kluever V, (...), Fornasiero EF | Science Advances | 2019 | | |
| Sharing Data from Molecular Simulations | | Abraham M, Apostolov R, (...), Zhmurov A | Journal of Chemical Information and Modeling | 2019 | | |
| Dynamic instability of clathrin assembly provides proofreading control for endocytosis |
| Chen Y, Yong J, (...), Wu M | Journal of Cell Biology | 2019 | | |
| Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography |
| Töpperwien M, Markus A, Alves F, Salditt T | Neuroimage | 2019 | | |
| Organization and regulation of gene transcription | | Cramer P | Nature | 2019 | | |
| Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation |
| Alsina KM, Hulsurkar M, (...), Wehrens XH | Circulation | 2019 | | |
| Molecular contribution function in RESOLFT nanoscopy |
| Frahm L, Keller-Findeisen J, (...), Hell SW | Optics Express | 2019 | | |
| Frame-constrained Total Variation Regularization for White Noise Regression |
| del Álamo M, Li H, Munk A | arXiv | 2019 | | |
| High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB |
| Bartsch A, Llabrés S, (...), Steinem C | Scientific Reports | 2019 | | |
| Multiscale change-point segmentation: beyond step functions |
| Li H, Guo Q, Munk A | Electronic Journal of Statistics | 2019 | | |
| A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice |
| Al‐Moyed H, Cepeda AP, Jung S, Moser T, Kügler S, Reisinger E | EMBO Molecular Medicine | 2018 | | |
| The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain |
| Mandad S, Rahman R, (...), Fornasiero EF | Scientific Reports | 2018 | | |
| Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy |
| Heras‐Garvin A, Weckbecker D, (...), Stefanova N | Movement Disorders | 2018 | | |
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