3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models |
| Saleem HN, Ignatyeva N, Stuut C, Jakobs S, Habeck M, Ebert A | Cells | 2024 | | |
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach |
| Dreha‐Kulaczewski S, Sahoo P, (...), Gärtner J | Journal of Inherited Metabolic Disease | 2024 | | |
H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6 |
| Sokpor G, Kerimoglu C, (...), Tuoc T | Biology (Basel) | 2024 | | |
Chemical synthesis of site-selective advanced glycation end products in α-synuclein and its fragments | | Bosbach C, Gatzemeier LM, (...), Outeiro TF | Organic & Biomolecular Chemistry | 2024 | | |
Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment | | Xu X, Tan X, (...), Hasenfuß G | Cardiovascular Research | 2024 | | |
Transient Non-local Interactions Dominate the Dynamics of Measles Virus N TAIL |
| Otteson L, Nagy G, (...), Vaiana SM | bioRxiv | 2024 | | |
Power-law adaptation in the presynaptic vesicle cycle |
| Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli S, Priesemann V | bioRxiv | 2024 | | |
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites |
| Antonicka H, Weraarpachai W, Vučković A, Hillen HS, Shoubridge EA | bioRxiv | 2024 | | |
Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response |
| Hendrickson T, Abigail Giese A, (...), Altamirano F | bioRxiv | 2024 | | |
Calcium-triggered (de)ubiquitination events in synapses |
| Ainatzi S, Kaufmann SV, (...), Urlaub H | bioRxiv | 2024 | | |
Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy | | Paulke NJ, Fleischhacker C, (...), Brandenburg S | Circulation Research | 2024 | | |
Early mutational signatures and transmissibility of SARS-CoV-2 Gamma and Lambda variants in Chile |
| Oróstica KY, Mohr SB, (...), Contreras S | Scientific Reports | 2024 | | |
Preparing primary sandwich hippocampal neuron cultures for cryo-electron tomography v1 |
| Domart F, Petrovic A, Do TT, Siegert A, Dresbach T, Fernández-Busnadiego R | protocols.io | 2024 | | |
Synthesis and Semi‐Synthesis of Alpha‐Synuclein: Insight into the Chemical Complexity of Synucleinopathies |
| Gatzemeier LM, Meyer F, Outeiro TF | ChemBioChem | 2024 | | |
Distributional limits of graph cuts on discretized grids |
| Suchan L, Li H, Munk A | arXiv | 2024 | | |
Human induced pluripotent stem cells for live cell cycle monitoring and endogenous gene activation |
| Kim R, Nagel SH, Liaw NY, Zimmermann W, Zelarayán LC, Schoger E | Stem Cell Research | 2024 | | |
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes |
| Amedei H, Paul NB, (...), Lenz C | Frontiers in Analytical Science | 2024 | | |
A versatile yeast model identifies the pesticides cymoxanil and metalaxyl as risk factors for synucleinopathies |
| Amaral L, Mendes F, Côrte-Real M, Rego A, Outeiro TF, Chaves SR | Chemosphere | 2024 | | |
Visible and near-infrared light-induced photoclick reactions | | Fu Y, Simeth NA, Szymanski W, Feringa BL | Nature Reviews Chemistry | 2024 | | |
Visualizing chaperonin function in situ by cryo-electron tomography |
| Wagner J, Carvajal AI, (...), Hartl FU | Nature | 2024 | | |
Optical control of pH via chromoselective photodosimetry |
| Chaudhuri A, Eijsink LE, Simeth NA | Chemical Communications | 2024 | | |
A Technique to Perform Structure–Function Analysis of Synapses | | Wichmann C, Michanski S | Neuromethods | 2024 | | |
Blood‐derived microRNAs are related to cognitive domains in the general population |
| Melas K, Talevi V, (...), Breteler MMB | Alzheimers & Dementia | 2024 | | |
Bleaching protection and axial sectioning in fluorescence nanoscopy through two-photon activation at 515 nm |
| Bredfeldt J, Oracz J, (...), Hell SW | Nature Communications | 2024 | | |
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish |
| Bornhorst D, Hejjaji AV, (...), Gunawan F | Nature Communications | 2024 | | |
Towards sustainable research data management of longitudinal, heterogeneous data from cardiac tissue engineering |
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Rational approximation of golden angles: Accelerated reconstructions for radial MRI |
| Scholand N, Schaten P, (...), Uecker M | Magnetic Resonance in Medicine | 2024 | | |
KRASG12C‐inhibitor‐based combination therapies for pancreatic cancer: insights from drug screening |
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MultiMatch: geometry-informed colocalization in multi-color super-resolution microscopy |
| Naas J, Nies G, (...), Munk A | Communications Biology | 2024 | | |
The plasma miRNAome in ADNI: Signatures to aid the detection of at‐risk individuals |
| Krüger DM, Pena‐Centeno T, (...), Fischer A | Alzheimers & Dementia | 2024 | | |
Volumetric changes of the enteric nervous system under physiological and pathological conditions measured using x‐ray phase‐contrast tomography |
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Plasma miRNAs across the Alzheimer's disease continuum: Relationship to central biomarkers |
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Sustainable Data Management for Single-Cell Sequencing: Tools, Platforms, and Challenges |
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Multiplex Microscopy Assay for Assessment of Therapeutic and Serum Antibodies against Emerging Pathogens |
| Sartingen N, Stürmer V, (...), Laketa V | Viruses | 2024 | | |
Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity |
| Karagulyan N, Überegger M, (...), Bandtlow C | bioRxiv | 2024 | | |
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts |
| Ruiz-Orera J, Miller DC, (...), Hübner N | Nature Cardiovascular Research | 2024 | | |
MALDI imaging combined with two-photon microscopy reveals local differences in the heterogeneity of colorectal cancer |
| Bharti A, Ajinkya K, (...), Oliver K | npj Imaging | 2024 | | |
Substitution of Met-38 to Ile in γ-synuclein found in two patients with amyotrophic lateral sclerosis induces aggregation into amyloid |
| Aubrey LD, Ninkina N, (...), Radford SE | Proceedings of the National Academy of Sciences of the United States of America | 2024 | | |
Structural and functional insights into tRNA recognition by human tRNA guanine transglycosylase | | Sievers K, Neumann P, (...), Ficner R | Structure | 2024 | | |
Acute antiarrhythmic effects of SGLT2 inhibitors–dapagliflozin lowers the excitability of atrial cardiomyocytes |
| Paasche A, Wiedmann F, (...), Schmidt C | Basic Research in Cardiology | 2024 | | |
Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins |
| Eria-Oliveira A, Folacci M, (...), Vivaudou M | Nature Communications | 2024 | | |
Local Water Content in Polymer Gels Measured With Super‐Resolved Fluorescence Lifetime Imaging | | Jana S, Nevskyi O, (...), Wöll D | Angewandte Chemie-International Edition | 2024 | | |
Thermogenetics for cardiac pacing |
| Balatskiy AV, Nesterenko AM, (...), Belousov VV | bioRxiv | 2024 | | |
Non-invasive analysis of contractility during identical maturations revealed two phenotypes in ventricular but not in atrial iPSC-CM | | Rapöhn M, Cyganek L, Voigt N, Hasenfuß G, Lehnart SE, Wegener JW | American Journal of Physiology-Heart and Circulatory Physiology | 2024 | | |
Image restoration of degraded time-lapse microscopy data mediated by near-infrared imaging |
| Gritti N, Power RM, Graves A, Huisken J | Nature Methods | 2024 | | |
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria |
| Poerschke S, Oeljeklaus S, (...), Rehling P | Molecular Cell | 2024 | | |
Rational Approximation of Golden Angles for Simple and Reproducible Radial Sampling |
| Scholand N, Graf C, Mackner D, Holme HCM, Uecker M | arXiv | 2024 | | |
Uncovering potential diagnostic and pathophysiological roles of α‐synuclein and DJ‐1 in melanoma |
| Quesnel A, Martin LD, (...), Filippou PS | Cancer Medicine | 2024 | | |
Drosophila MIC10b can polymerize into cristae-shaping filaments |
| Stephan T, Stoldt S, (...), Jakobs S | Life Science Alliance | 2024 | | |
Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing |
| Reichmann J, Sarrazin C, (...), Salditt T | bioRxiv | 2024 | | |
Expansion of the complex genotypic and phenotypic spectrum of FGFR2-associated neurocutaneous syndromes |
| Schmidt J, Kaulfuß S, (...), Wollnik B | Human Genetics | 2024 | | |
Vesicle condensation induced by synapsin: condensate size, geometry, and vesicle shape deformations |
| Alfken J, Neuhaus C, (...), Salditt T | European Physical Journal E | 2024 | | |
High throughput methods for cardiac cellular electrophysiology studies: The road to personalized medicine | | Seibertz F, Voigt N | American Journal of Physiology-Heart and Circulatory Physiology | 2024 | | |
Genome engineering of a neuronal specific, optogenetic, induced pluripotent stem cell line |
| Schmoll AK, Mager T, Tse TP, Alameldeen A, Zimmermann W, Zafeiriou M | Stem Cell Research | 2024 | | |
Characterizing ATP processing by the AAA+ protein p97 at the atomic level |
| Shein M, Hitzenberger M, (...), Schütz AK | Nature Chemistry | 2024 | | |
Structural mechanisms of autoinhibition and substrate recognition by the ubiquitin ligase HACE1 |
| Düring J, Wolter M, (...), Lorenz S | Nature Structural & Molecular Biology | 2024 | | |
CryoRhodopsins: a comprehensive characterization of a new clade of microbial rhodopsins from cold environments |
| Lamm G, Marin E, (...), Kovalev K | bioRxiv | 2024 | | |
Metal-Induced Energy Transfer (MIET) Imaging of Cell Surface Engineering with Multivalent DNA Nanobrushes | | Wang D, Liu B, (...), Chen T | ACS Nano | 2024 | | |
Preclinical evaluation of CRISPR-based therapies for Noonan syndrome caused by deep-intronic LZTR1 variants |
| Knauer C, Haltern H, (...), Cyganek L | Molecular Therapy-Nucleic Acids | 2024 | | |
Model-Based Reconstruction for Joint Estimation of $T_{1}$, $R_{2}^{*}$ and $B_{0}$ Field Maps Using Single-Shot Inversion-Recovery Multi-Echo Radial FLASH |
| Wang X, Scholand N, (...), Uecker M | arXiv | 2024 | | |
SERCA2a microdomain cAMP changes in heart failure with preserved ejection fraction | | Gotthardt M, Lehnart SE | Cardiovascular Research | 2024 | | |
In-situ architecture of the human prohibitin complex |
| Lange F, Ratz M, (...), Jakobs S | bioRxiv | 2024 | | |
Mouse oocytes sequester aggregated proteins in degradative super-organelles |
| Zaffagnini G, Cheng S, (...), Böke E | Cell | 2024 | | |
Near-optimal information relay by the neuronal population of layer 4 barrel cortex |
| Revah O, Wolf F, Gutnick MJ, Neef A | bioRxiv | 2024 | | |
A metabolically controlled contact site between vacuoles and lipid droplets in yeast |
| Diep DTV, Collado J, (...), Bohnert M | Developmental Cell | 2024 | | |
RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis |
| Prusty AB, Hirmer A, (...), Fischer U | Cell Reports | 2024 | | |
Human serum-derived α-synuclein auto-antibodies mediate NMDA receptor-dependent degeneration of CNS neurons |
| Garg P, Würtz F, (...), Bähr M | Journal of Neuroinflammation | 2024 | | |
Inhibition of 26S proteasome activity by α‐synuclein is mediated by the proteasomal chaperone Rpn14/PAAF1 |
| Galka D, Ali TT, (...), Braus GH | Aging Cell | 2024 | | |
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy |
| Schwenzer N, Tsukanov R, (...), Lehnart SE | bioRxiv | 2024 | | |
Measuring sub-nanometer undulations at microsecond temporal resolution with metal- and graphene-induced energy transfer spectroscopy |
| Chen T, Karedla N, Enderlein J | Nature Communications | 2024 | | |
Structure of the multi-subunit chloroplast RNA polymerase |
| do Prado PF, Ahrens FM, (...), Hillen HS | Molecular Cell | 2024 | | |
MultiMatch: Geometry-Informed Colocalization in Multi-Color Super-Resolution Microscopy |
| Naas J, Nies G, (...), Munk A | bioRxiv | 2024 | | |
Variance sum rule for entropy production | | Di Terlizzi I, Gironella M, (...), Ritort F | Science | 2024 | | |
Cytoarchitecture of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography: imaging workflow and classification for drug testing |
| Salditt T, Reichmann J, (...), Balkema-Buschmann A | Researchsquare | 2024 | | |
Synphilin-1 as a modulator of aSyn assembly |
| Lázaro DF, Amen T, (...), Outeiro TF | bioRxiv | 2024 | | |
3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes |
| Pochechueva TV, Schwenzer N, (...), Lehnart SE | International Journal of Molecular Sciences | 2024 | | |
The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3’-UTR and promoting Rag1 mRNA expression |
| Xu M, Ito-Kureha T, (...), Heissmeyer V | Nature Communications | 2024 | | |
Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies |
| Sridhar S, Vystrčilová M, (...), Gollisch T | bioRxiv | 2024 | | |
Convolutional neural network models of the primate retina reveal adaptation to natural stimulus statistics |
| Vystrčilová M, Sridhar S, Burg MF, Gollisch T, Ecker AS | bioRxiv | 2024 | | |
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40) |
| Frieg B, Han M, (...), Schröder GF | Nature Communications | 2024 | | |
A Single-Cell Transcriptomic Analysis of the Mouse Hippocampus After Voluntary Exercise |
| Methi A, Islam MR, (...), Fischer A | Molecular Neurobiology | 2024 | | |
Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopy | | D’Amico L, Svetlove A, (...), Dullin C | Computers in Biology and Medicine | 2024 | | |
Most discriminative stimuli for functional cell type clustering |
| Burg MF, Zenkel T, (...), Ecker AS | arXiv | 2024 | | |
Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions |
| Bloothooft M, Verbruggen B, Seibertz F, Heyden MAGvd, Voigt N, de Boer TP | Frontiers in Physiology | 2024 | | |
Biallelic NAA60 variants with impaired n-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications |
| Chelban V, Aksnes H, (...), Houlden H | Nature Communications | 2024 | | |
mtDNA Analysis using Mitopore |
| Dobner J, Nguyen T, (...), Rossi A | Molecular Therapy-Methods & Clinical Development | 2024 | | |
NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals |
| Mougios N, Cotroneo ER, (...), Opazo F | bioRxiv | 2024 | | |
Hörvermögen wiederherstellen mit Optogenetik | | Moser T | Sprache-Stimme-Gehör | 2024 | | |
Adsorption of alpha-synuclein and inhibition of fibril formation by nanocellulose and gold-coated-nanocellulose |
| Lamtar Mohammadi E, Keikha R, Outeiro TF, Jebali A | Cellulose | 2024 | | |
RAPP-containing arrest peptides induce translational stalling by short circuiting the ribosomal peptidyltransferase activity |
| Morici M, Gabrielli S, (...), Wilson DN | Nature Communications | 2024 | | |
Multiscale Quantile Regression with Local Error Control |
| Liu Z, Li H | arXiv | 2024 | | |
Formation of memory assemblies through the DNA-sensing TLR9 pathway |
| Jovasevic V, Wood EM, (...), Radulovic J | Nature | 2024 | | |
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice |
| Kaurani L, Islam MR, (...), Fischer A | EMBO Journal | 2024 | | |
Gene therapy for deafness: are we there now? |
| Moser T, Chen H, Kusch K, Behr R, Vona B | EMBO Molecular Medicine | 2024 | | |
Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures |
| Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF, Geraldes V | Biomedicines | 2024 | | |
Robust inference of cooperative behaviour of multiple ion channels in voltage-clamp recordings |
| Requadt R, Fink M, Kubica P, Steinem C, Munk A, Li H | arXiv | 2024 | | |
[11C]MODAG 005 – a novel PET tracer targeting alpha-synuclein aggregates in the brain |
| Saw RS, Buss S, (...), Herfert K | Researchsquare | 2024 | | |
METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway |
| Ma L, Zhou X, (...), Pan Y | Cell Death & Disease | 2024 | | |
Structural basis of Integrator-dependent RNA polymerase II termination |
| Fianu I, Ochmann M, (...), Cramer P | Nature | 2024 | | |
Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion |
| López-Murcia FJ, Lin K, (...), Taschenberger H | Proceedings of the National Academy of Sciences of the United States of America | 2024 | | |
Molecular basis of human nuclear and mitochondrial tRNA 3'-processing |
| Bhatta A, Kuhle B, (...), Hillen H | bioRxiv | 2024 | | |
Super-resolution going viral: T4 virus particles as perfect nature-designed 3D-Bio-NanoRulers |
| Gallea JI, Nevskyi O, (...), Enderlein J | bioRxiv | 2024 | | |
How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA | | Höbartner C, Bohnsack KE, Bohnsack MT | Annual Review of Biochemistry | 2024 | | |
Computational functions of precisely balanced neuronal assemblies in an olfactory memory network |
| Meissner-Bernard C, Jenkins B, (...), Frank T | bioRxiv | 2024 | | |
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway |
| Oliveira da Silva MI, Santejo M, (...), Liz MA | Cell Death & Disease | 2024 | | |
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy | | Wali R, Xu H, (...), Ebert A | Biological Chemistry | 2024 | | |
Insights into cochlear structure by innovative light sheet fluorescence microscopy |
| Roos L, Aakthe M, (...), Moser T | Laryngo-Rhino-Otologie | 2024 | | |
In situ studies of membrane biology by cryo-electron tomography |
| Keller J, Fernández-Busnadiego R | Current Opinion in Cell Biology | 2024 | | |
Myosin II actively regulates Drosophila proprioceptors |
| Guan C, Nishi K, Kreis CT, Bäumchen O, Göpfert MC, Schmidt CF | bioRxiv | 2024 | | |
A role for astrocytic miR-129-5p in Frontotemporal Dementia |
| Kaurani L, Pradhan R, (...), Fischer A | bioRxiv | 2024 | | |
Microtubules: highway to … arrhythmia? |
| Liutkute A, Prosser BL, Voigt N | Cardiovascular Research | 2024 | | |
Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment |
| Weigel M, Dechent P, (...), Granziera C | bioRxiv | 2024 | | |
Profiling the LAM family of contact site tethers provides insights into their regulation and function |
| Fenech EJ, Kupervaser M, (...), Schuldiner M | bioRxiv | 2024 | | |
Click Chemistry with Cell-Permeable Fluorophores Expands the Choice of Bioorthogonal Markers for Two-Color Live-Cell STED Nanoscopy |
| Gregor C, Grimm F, Rehman J, Wurm CA, Egner A | Cells | 2024 | | |
A subgroup of light-driven sodium pumps with an additional Schiff base counterion |
| Podoliak E, Lamm GHU, (...), Kovalev K | Nature Communications | 2024 | | |
Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy |
| Gligonov I, Enderlein J | bioRxiv | 2024 | | |
Toward Optogenetic Hearing Restoration | | Huet A, Mager T, Gossler C, Moser T | Annual Review of Neuroscience | 2024 | | |
Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice |
| Outeiro TF, Kalia LV, (...), Svenningsson P | Movement Disorders | 2024 | | |
Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT |
| Oleksiievets N, Mougios N, (...), Tsukanov R | bioRxiv | 2024 | | |
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation |
| Maurer W, Rebs S, (...), Streckfuss-Bömeke K | Stem Cell Research | 2024 | | |
Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues |
| Arora B, Kulkarni A, (...), Ramos-Gomes F | Scientific Reports | 2024 | | |
3D imaging of protein aggregates in human neurodegeneration by multiscale X-ray phase-contrast tomography |
| Reichmann J, Franz J, Eckermann M, Stadelmann C, Salditt T | medRxiv | 2024 | | |
Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts |
| Foo B, Amedei H, (...), Lehnart SE | bioRxiv | 2024 | | |
The SecM arrest peptide traps a pre-peptide bond formation state of the ribosome |
| Gersteuer F, Morici M, (...), Wilson DN | Nature Communications | 2024 | | |
A small step towards an important goal: fragment screen of the c-di-AMP-synthesizing enzyme CdaA |
| Neumann P, Heidemann JL, (...), Ficner R | Acta Crystallographica Section D-Structural Biology | 2024 | | |
An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells |
| Chen J, Stephan T, (...), Chen Z | Proceedings of the National Academy of Sciences of the United States of America | 2024 | | |
Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders |
| Poschmann J, Solomon P, (...), Heilbronner U | Researchsquare | 2024 | | |
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match |
| Bock LV, Igaev M, Grubmüller H | Current Opinion in Structural Biology | 2024 | | |
Through the Haze: Unveiling the Link Between Smoking and Atrial Fibrillation | | Mason FE, Voigt N | American Journal of Physiology-Heart and Circulatory Physiology | 2024 | | |
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling |
| Schoger E, Bleckwedel F, (...), Zelarayán LC | Communications Biology | 2024 | | |
CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy |
| Schwenzer N, Teiwes NK, (...), Steinem C | Communications Biology | 2024 | | |
The molecular machinery for maturation of primary mtDNA transcripts |
| Vučković A, Freyer C, Wredenberg A, Hillen HS | Human Molecular Genetics | 2024 | | |
Coordinating mitochondrial translation with assembly of the OXPHOS complexes |
| Kremer LS, Rehling P | Human Molecular Genetics | 2024 | | |
CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release |
| Velychko T, Mohammad E, (...), Lidschreiber M | Molecular Cell | 2024 | | |
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications | | Bode D, Pronto JRD, Schiattarella GG, Voigt N | Nature Reviews Cardiology | 2024 | | |
Characterizing intracellular mechanics via optical tweezers-based microrheology |
| Vos BE, Muenker TM, Betz T | Current Opinion in Cell Biology | 2024 | | |
Catching up but still miles behind—a patient registry for otoferlin |
| Vona B, Wollnik B, Strenzke N, Moser T | Experimental & Molecular Medicine | 2024 | | |
Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresis | | Schröder S, Epple R, Fischer A, Schettler VJJ | Therapeutic Apheresis and Dialysis | 2024 | | |
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system |
| Raimi OG, Ojha H, (...), Muqit MMK | Science Advances | 2024 | | |
GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases |
| Hsieh T, Lesmann H, (...), Olinger E | Researchsquare | 2024 | | |
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity |
| Harasimov K, Gorry RL, (...), Schuh M | Nature Cell Biology | 2024 | | |
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS |
| Chatterjee M, Özdemir S, (...), Schneider A | Nature Medicine | 2024 | | |
Autonomous bioluminescence emission from transgenic mice |
| Kiszka KA, Dullin C, (...), Gregor C | bioRxiv | 2024 | | |
X-ray phase-contrast tomography of cells manipulated with an optical stretcher |
| Burchert J, Frohn J, (...), Köster S | Journal of Synchrotron Radiation | 2024 | | |
Lysosomal signalling pathways influence heart rhythm, and regulate atrial function |
| Capel RA, Akerman E, (...), Burton RAB | bioRxiv | 2024 | | |
Open Problem: Active Representation Learning |
| Milosevic N, Müller G, Huisken J, Scherf N | arXiv | 2024 | | |
Lipidic folding pathway of α-Synuclein via a toxic oligomer |
| Griesinger C, Sant V, (...), Andreas L | Researchsquare | 2024 | | |
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice |
| Edelman BJ, Siegenthaler D, (...), Macé E | PLOS Biology | 2024 | | |
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation | | Fakuade FE, Hubricht D, (...), Voigt N | Circulation | 2024 | | |
Aging and neurodegeneration: From molecular mechanisms to therapeutic interventions |
| Outeiro TF, Brocardo PS, Gelain DP | Journal of Neurochemistry | 2024 | | |
Structural insights into the regulation of RyR1 by S100A1 |
| Weninger G, Miotto MC, (...), Marks AR | Proceedings of the National Academy of Sciences of the United States of America | 2024 | | |
Interfering with aggregated α-synuclein in advanced melanoma leads to a major upregulation of MHC class II proteins | | Fokken C, Silbern I, (...), Becker D | Melanoma Research | 2024 | | |
A roadmap for ribosome assembly in human mitochondria |
| Lavdovskaia E, Hanitsch E, (...), Richter-Dennerlein R | Nature Structural & Molecular Biology | 2024 | | |
Neurofilament Light Chain Serum Levels Mirror Age and Disability in Secondary Progressive Multiple Sclerosis |
| Husseini L, Jung J, (...), Weber MS | Neurology Neuroimmunology & Neuroinflammation | 2024 | | |
Microlens arrays for multichannel laser-to-waveguide coupling | | Kunze K, Gossler C, Peters V, Keppeler D, Moser T, Schwarz UT | Applied Optics | 2024 | | |
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study |
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Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome |
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Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis |
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Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses |
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PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer’s Disease |
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Accessing activity and viscoelastic properties of artificial and living systems from passive measurement | | Muenker TM, Knotz G, Krüger M, Betz T | Nature Materials | 2024 | | |
Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy | | Radmacher N, Nevskyi O, (...), Enderlein J | Nature Photonics | 2024 | | |
Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications to ion channels |
| Jula Vanegas L, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk A | Annals of Applied Statistics | 2024 | | |
Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons |
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Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse |
| Hain PJH, Moser T | Frontiers in Molecular Neuroscience | 2024 | | |
CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells |
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3D imaging of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography enables drug testing |
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Machine learning and advanced statistical analysis for fluorescence correlation spectroscopy | | Enderlein J | Biophysical Journal | 2024 | | |
Towards a biological diagnosis of PD |
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Live cell Imaging of yeast cells expressing human PINK1-GFP and the TOM complex subunits v1 |
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Establishing synthetic ribbon-type active zones in a heterologous expression system |
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Establishing synthetic ribbon-type active zones in a heterologous expression system |
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Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina |
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mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes |
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The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites |
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Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88 |
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Circulating microRNAs are related to cognitive domains in the general population |
| Melas K, Talevi V, (...), Breteler MM | medRxiv | 2024 | | |
Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain |
| Herwerth M, Wyss MT, (...), Weber B | bioRxiv | 2024 | | |
Autophagy preferentially degrades non-fibrillar polyQ aggregates |
| Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling F | Molecular Cell | 2024 | | |
Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness |
| Haertter D, Hauke L, Driehorst T, Nishi K, Zimmermann W, Schmidt CF | bioRxiv | 2024 | | |
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver |
| Aich A, Patrick G, Rehling P | Zenodo | 2024 | | |
Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings |
| Michael M, Wolf BJ, Klinge-Strahl A, Jeschke M, Moser T, Dieter A | Brain Stimulation | 2023 | | |
The unique biomechanics of intermediate filaments – From single filaments to cells and tissues | | Rölleke U, Kumari P, Meyer R, Köster S | Current Opinion in Cell Biology | 2023 | | |
Tracking cell turnover in human brain using 15N-thymidine imaging mass spectrometry |
| Roeder SS, Bonnin EA, (...), Huttner HB | Frontiers in Neuroscience | 2023 | | |
PrP meets alpha‐synuclein: Molecular mechanisms and implications for disease |
| Vieira TCRG, Barros CA, Domingues R, Outeiro TF | Journal of Neurochemistry | 2023 | | |
High-resolution analysis of bound Ca2+ in neurons and synapses |
| Bonnin EA, Golmohammadi A, Rehm R, Tetzlaff C, Rizzoli SO | Life Science Alliance | 2023 | | |
Fluorophore position of headgroup-labeled Gb3 glycosphingolipids in lipid bilayers | | Socrier L, Sharma A, (...), Steinem C | Biophysical Journal | 2023 | | |
FGFR1 variants contributed to families with tooth agenesis |
| Yao S, Zhou X, (...), Pan Y | Human Genomics | 2023 | | |
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria |
| Klein AD, Outeiro TF | Nature Communications | 2023 | | |
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices |
| Jentoft IM, Bäuerlein FJ, (...), Schuh M | Cell | 2023 | | |
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs |
| Shi R, Reichardt M, (...), Brügmann T | Cardiovascular Research | 2023 | | |
An NFATc1/SMAD3/cJUN complex restricted to SMAD4-deficient pancreatic cancer guides rational therapies | | Hasselluhn MC, Schlösser D, (...), Hessmann E | Gastroenterology | 2023 | | |
Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis |
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Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome |
| Kutschka I, Bertero E, (...), Dudek J | Basic Research in Cardiology | 2023 | | |
Structure of the transcribing RNA polymerase II–Elongin complex |
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Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders |
| Kaiyrzhanov R, Rad A, (...), Maroofian R | Brain | 2023 | | |
Approaching automation of multiple instance orchestration of the menoci web portal |
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Efficient and sustained optogenetic control of nervous and cardiac systems |
| Zerche M, Hunniford V, (...), Moser T | bioRxiv | 2023 | | |
Unraveling haplotype errors in the DFNA33 locus |
| Vona B, Regele S, (...), Am Zehnhoff-Dinnesen AG | Frontiers in Genetics | 2023 | | |
Prediction mismatch responses arise as corrections of a predictive spiking code |
| van Driel K, Rudelt L, Priesemann V, Mikulasch FA | bioRxiv | 2023 | | |
Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency |
| Schlotawa L, Matysiak K, (...), Gärtner J | Neuropediatrics | 2023 | | |
Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis. |
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A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca 2+ uptake |
| Wegener JW, Mitronova GY, (...), Lehnart SE | Life Science Alliance | 2023 | | |
Ca2+ regulation of glutamate release from inner hair cells of hearing mice |
| Jaime Tobón LM, Moser T | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity |
| Altas B, Rhee H, (...), Kawabe H | Journal of Cell Biology | 2023 | | |
Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach |
| Svetlove A, Ritter CO, (...), Unterberg-Buchwald C | European Radiology Experimental | 2023 | | |
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in <i>Bacillus subtilis in vitro</i> |
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Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus |
| Hintze A, Lange F, (...), Wichmann C | iScience | 2023 | | |
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing |
| Schreiber M, Zafeiriou M | Stem Cell Research | 2023 | | |
Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing |
| Chen H, Monga M, (...), Moser T | Protein & Cell | 2023 | | |
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy |
| Kyriakopoulou E, Versteeg D, (...), van Rooij E | Nature Cardiovascular Research | 2023 | | |
Protein nanobarcodes enable single-step multiplexed fluorescence imaging |
| de Jong-Bolm D, Sadeghi M, (...), Rizzoli SO | PLOS Biology | 2023 | | |
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners |
| Kanwal N, Krogh N, (...), Bohnsack M | Nucleic Acids Research | 2023 | | |
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis | | Galbusera R, Bahn E, (...), Granziera C | Neurology | 2023 | | |
Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses | | Altas B, Tuffy LP, (...), Poulopoulos A | Biological Psychiatry | 2023 | | |
Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells |
| Schreiber M, Zafeiriou M | Stem Cell Research | 2023 | | |
Protocol to develop force-generating human skeletal muscle organoids |
| Shahriyari M, Rinn M, Hofemeier AD, Babych A, Zimmermann W, Tiburcy M | STAR Protocols | 2023 | | |
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell |
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Implications for neutrophils in cardiac arrhythmias | | Hegemann N, Barth L, Doering Y, Voigt N, Grune J | American Journal of Physiology-Heart and Circulatory Physiology | 2023 | | |
Structure and dynamics of human cardiac fibroblast nanotubes |
| Schmid-Herbstritt S, Stief G, (...), Rog-Zielinska E | bioRxiv | 2023 | | |
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis |
| Wicke D, Neumann P, (...), Stülke J | bioRxiv | 2023 | | |
Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes |
| Harasimov K, Uraji J, (...), Schuh M | Nature Cell Biology | 2023 | | |
Age-dependent structural reorganization of utricular ribbon synapses |
| Michanski S, Henneck T, (...), Wichmann C | Frontiers in Cell and Developmental Biology | 2023 | | |
Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls |
| Senner F, Schneider-Axmann T, (...), Schulze TG | Schizophrenia Research-Cognition | 2023 | | |
Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restoration | | Zerche M, Wrobel C, Kusch K, Moser T, Mager T | Molecular Therapy-Methods & Clinical Development | 2023 | | |
Correction to: Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism |
| Wohlfarter Y, Eidelpes R, (...), Keller MA | Cellular and Molecular Life Sciences | 2023 | | |
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons |
| Weichard I, Taschenberger H, (...), Nerlich J | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
Herzbeteiligung beo COVID-19: Makrophagen-getriebene Entzündung und Gefäßneubildung |
| Werlein C, Ackermann M, (...), Jonigk D | Pneumologie | 2023 | | |
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly |
| Schnabel F, Schuler E, (...), Yigit G | Human Genetics | 2023 | | |
Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility |
| Liebe NL, Mey I, (...), Steinem C | ACS Applied Materials & Interfaces | 2023 | | |
Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins |
| Hauke L, Isbaner S, (...), Enderlein J | ACS Nano | 2023 | | |
Minimax detection of localized signals in statistical inverse problems | | Pohlmann M, Werner F, Munk A | Information and Inference-A Journal of the IMA | 2023 | | |
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming |
| Zhang Z, Wang X, (...), Hessmann E | Cellular and Molecular Gastroenterology and Hepatology | 2023 | | |
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins |
| Schmidt A, Finegan T, (...), Peifer M | Molecular Biology of the Cell | 2023 | | |
Roadmap for optical tweezers |
| Volpe G, Maragò OM, (...), Swartzlander GA | Journal of Physics-Photonics | 2023 | | |
Simulation of Complex Biomolecular Systems: The Ribosome Challenge |
| Bock LV, Gabrielli S, Kolář MH, Grubmüller H | Annual Review of Biophysics | 2023 | | |
Statistical Analysis of Random Objects Via Metric Measure Laplacians | | Mordant G, Munk A | SIAM Journal on Mathematics of Data Science | 2023 | | |
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity |
| Stewart H, Lu Y, (...), Firth AE | iScience | 2023 | | |
The Ultrametric Gromov–Wasserstein Distance | | Mémoli F, Munk A, Wan Z, Weitkamp C | Discrete & Computational Geometry | 2023 | | |
Cryo-EM for Structure Determination of Mitochondrial Ribosome Samples | | Hillen HS | Methods in Molecular Biology | 2023 | | |
The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation |
| Pikunov AV, Syunyaev RA, (...), Efimov IR | bioRxiv | 2023 | | |
Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease” |
| Outeiro TF, Alcalay RN, (...), Ferreira JJ | Movement Disorders | 2023 | | |
The promise of optogenetic arrhythmia termination |
| Bruegmann T, Sacconi L | Journal of Internal Medicine | 2023 | | |
Author Correction: Selective optogenetic control of Gq signaling using human Neuropsin |
| Wagdi A, Malan D, (...), Bruegmann T | Nature Communications | 2023 | | |
Empirical Optimal Transport under Estimated Costs: Distributional Limits and Statistical Applications |
| Hundrieser S, Mordant G, Weitkamp CA, Munk A | arXiv | 2023 | | |
Translation Factor Accelerating Peptide Bond Formation on the Ribosome: EF-P and eIF5A as Entropic Catalysts and a Potential Drug Targets |
| Mudryi V, Peske F, Rodnina M | BBA Advances | 2023 | | |
Impact of the Euro 2020 championship on the spread of COVID-19 |
| Dehning J, Mohr SB, (...), Priesemann V | Nature Communications | 2023 | | |
Structural insights into human co-transcriptional capping | | Garg G, Dienemann C, (...), Cramer P | Molecular Cell | 2023 | | |
Trafficking proteins show limited differences in mobility across different postsynaptic spines |
| Mougios N, Opazo F, Rizzoli SO, Reshetniak S | iScience | 2023 | | |
Membrane-Bound Vimentin Filaments Reorganize and Elongate under Strain |
| Nageswaran S, Haipeter J, Bodenschatz JFE, Meyer R, Köster S, Steinem C | Biomacromolecules | 2023 | | |
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling |
| Schoger E, Bleckwedel F, (...), Zelarayán LC | Communications Biology | 2023 | | |
The long-loop recycling (LLR) of synaptic components as a question of economics |
| Georgiev SV, Rizzoli SO | Molecular and Cellular Neuroscience | 2023 | | |
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy |
| Flores-Leon M, Outeiro TF | Acta Neuropathologica | 2023 | | |
Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes |
| Chen T, Ghosh A, Enderlein J | Nano Letters | 2023 | | |
Force generation in human blood platelets by filamentous actomyosin structures |
| Zelená A, Blumberg J, (...), Köster S | Biophysical Journal | 2023 | | |
Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy |
| Laitenberger O, Aspelmeier T, Staudt T, Geisler C, Munk A, Egner A | Nanomaterials | 2023 | | |
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users |
| Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser T | Frontiers in Neuroscience | 2023 | | |
Graded optogenetic activation of the auditory pathway for hearing restoration |
| Mittring A, Moser T, Huet A | Brain Stimulation | 2023 | | |
Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington’s Disease Effects in YAC128 Mice |
| Plácido E, Gomes Welter P, (...), Brocardo PS | International Journal of Molecular Sciences | 2023 | | |
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome |
| Busley AV, Gutiérrez-Gutiérrez Ó, (...), Cyganek L | bioRxiv | 2023 | | |
Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses |
| Karagulyan N, Moser T | Frontiers in Molecular Neuroscience | 2023 | | |
Natural stimuli drive concerted nonlinear responses in populations of retinal ganglion cells |
| Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch T | bioRxiv | 2023 | | |
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes |
| Weber F, Klas S, (...), Cyganek L | Social Science Research Network | 2023 | | |
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease |
| Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci A | International Journal of Molecular Sciences | 2023 | | |
Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes |
| Haro-Moreno JM, López-Pérez M, (...), Rodriguez-Valera F | bioRxiv | 2023 | | |
X-ray phase-contrast 3D virtual histology characterises complex tissue architecture in colorectal cancer |
| Svetlove A, Griebel T, (...), Dullin C | Frontiers in Gastroenterology | 2023 | | |
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome |
| Akol I, Izzo A, (...), Vogel T | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion |
| Podoliak E, Lamm GHU, (...), Kovalev K | bioRxiv | 2023 | | |
An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex |
| Enz LS, Winkler A, (...), Schaeren-Wiemers N | International Journal of Molecular Sciences | 2023 | | |
Synapsin condensation controls synaptic vesicle sequestering and dynamics |
| Hoffmann C, Rentsch J, (...), Milovanovic D | Nature Communications | 2023 | | |
CaBP1 and 2 enable sustained CaV 1.3 calcium currents and synaptic transmission in inner hair cells |
| Oestreicher D, Chepurwar S, (...), Pangrsic T | bioRxiv | 2023 | | |
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system |
| Saha I, Yuste-Checa P, (...), Hipp MS | Nature Communications | 2023 | | |
ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals |
| Binotti B, Ninov M, (...), Jahn R | Autophagy | 2023 | | |
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF |
| Antoniou A, Auderset L, (...), Schneider A | Cell Reports | 2023 | | |
Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina |
| Krüppel S, Khani MH, (...), Gollisch T | bioRxiv | 2023 | | |
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency |
| Schlotawa L, Tyka K, (...), Gärtner J | EMBO Molecular Medicine | 2023 | | |
HAV‐Peptides Attached to Colloidal Probes Faithfully Detect E‐Cadherins Displayed on Living Cells |
| Toy S, Dietz J, (...), Janshoff A | Chemistry-A European Journal | 2023 | | |
Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reaction | | Fu Y, Simeth NA, Toyoda R, Brilmayer R, Szymanski W, Feringa BL | Angewandte Chemie-International Edition | 2023 | | |
Lysinuric protein intolerance caused by a homozygous SLC7A7 deletion and presented with hyperferritinemia and osteoporosis in two siblings |
| Kalay I, Aykut H, Caliskan Z, Yigit G, Wollnik B | Molecular Genetics and Metabolism Reports | 2023 | | |
Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism |
| Grammatika Pavlidou N, Dobrev S, (...), Molina CE | European Heart Journal | 2023 | | |
Probing the role of the C2F domain of otoferlin |
| Chen H, Fang Q, Benseler F, Brose N, Moser T | Frontiers in Molecular Neuroscience | 2023 | | |
Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis |
| Sant'Anna R, Robbs BK, (...), Foguel D | bioRxiv | 2023 | | |
Spliceosome malfunction causes neurodevelopmental disorders with overlapping features |
| Li D, Wang Q, (...), Hakonarson H | Journal of Clinical Investigation | 2023 | | |
Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts |
| Castro-Hernández R, Berulava T, (...), Fischer A | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
The multifaceted mitochondrial OXA insertase |
| Homberg B, Rehling P, Cruz-Zaragoza LD | Trends in Cell Biology | 2023 | | |
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system |
| Raimi OG, Ojha H, (...), Muqit MMK | bioRxiv | 2023 | | |
Defective COX1 expression in aging mice liver |
| Witte S, Boshnakovska A, Özdemir M, Chowdhury A, Rehling P, Aich A | Biology Open | 2023 | | |
Observation of E-cadherin Adherens Junction Dynamics with Metal-Induced Energy Transfer Imaging and Spectroscopy |
| Chen T, Karedla N, Enderlein J | bioRxiv | 2023 | | |
In vitro reconstitution of chromatin domains |
| Quililan K, Oberbeckmann E, Cramer P, Oudelaar AM | bioRxiv | 2023 | | |
Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation |
| Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes V | Cells | 2023 | | |
SparseProp: Efficient Event-Based Simulation and Training of Sparse Recurrent Spiking Neural Networks |
| Engelken R | arXiv | 2023 | | |
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies |
| Hoffmann J, Hanß S, (...), Nauck N | Clinical Research in Cardiology | 2023 | | |
Excitation Intensity-Dependent Quantum Yield of Semiconductor Nanocrystals |
| Ghosh S, Ross U, (...), Chizhik AI | Journal of Physical Chemistry Letters | 2023 | | |
Impact of Phosphorylation on alpha-Synuclein Structural Determinants |
| Dorn AE, de Bruyn E, (...), Carloni P | bioRxiv | 2023 | | |
A quantitative fluorescence‐based approach to study mitochondrial protein import |
| Jain N, Gomkale R, Bernhard O, Rehling P, Cruz‐Zaragoza LD | EMBO reports | 2023 | | |
Mit Lichtstrahlen das Gehör wiederherstellen |
| Moser T | Zeitschrift für Audiologie-Audiological Acoustics | 2023 | | |
Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel | | Pan Y, Pohjolainen E, (...), Scheuring S | Nature Structural & Molecular Biology | 2023 | | |
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain |
| Schilbach S, Wang H, Dienemann C, Cramer P | Proceedings of the National Academy of Sciences of the United States of America | 2023 | | |
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes |
| Seibertz F, Sutanto H, (...), Voigt N | Basic Research in Cardiology | 2023 | | |
Towards a Biological Definition of Parkinson’s Disease |
| Höglinger GU, Adler CH, (...), Lang AE | Preprints | 2023 | | |
Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR |
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Reverse-time analysis uncovers universality classes in directional biological dynamics |
| Lenner N, Eule S, Großhans J, Wolf F | arXiv | 2023 | | |
Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise |
| Lenner N, Häring M, Eule S, Großhans J, Wolf F | arXiv | 2023 | | |
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons |
| Weichard I, Taschenberger H, (...), Nerlich J | bioRxiv | 2023 | | |
C1q is increased in cerebrospinal fluid‐derived extracellular vesicles in Alzheimer's disease: A multi‐cohort proteomics and immuno‐assay validation study |
| Chatterjee M, Özdemir S, (...), Schneider A | Alzheimers & Dementia | 2023 | | |
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination |
| Kapell H, Fazio L, (...), Schirmer L | Journal of Clinical Investigation | 2023 | | |
Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation |
| Gatzemeier LM, Meyer F, Diederichsen U, Outeiro TF | Chemistry-A European Journal | 2023 | | |
A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia |
| Kaurani L, Islam MR, (...), Fischer A | bioRxiv | 2023 | | |
Bayesian MRI reconstruction with joint uncertainty estimation using diffusion models |
| Luo G, Blumenthal M, Heide M, Uecker M | Magnetic Resonance in Medicine | 2023 | | |
A small-angle X-ray scattering study of red blood cells in continuous flow |
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IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart |
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Zelltypen aus menschlichen pluripotenten Zellen und deren Anwendung in Zelltherapien | | Zimmermann W, Ader M, (...), Tonn T | Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft | 2023 | | |
3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis |
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The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments |
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A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag |
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Influence of phosphorylation on intermediate filaments | | Kraxner J, Köster S | Biological Chemistry | 2023 | | |
Signatures of heterogeneity in the statistical structure of target state aligned ensembles |
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Adaptive minimax optimality in statistical inverse problems via SOLIT -- Sharp Optimal Lepskii-Inspired Tuning |
| Li H, Werner F | arXiv | 2023 | | |
Quantitative MRI by nonlinear inversion of the Bloch equations |
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Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V |
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Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V |
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The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued |
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Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis |
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A metabolically controlled contact site between lipid droplets and vacuoles |
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Vimentin intermediate filaments structure and mechanically support microtubules in cells |
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Protein transport along the presequence pathway | | Makki A, Rehling P | Biological Chemistry | 2023 | | |
Structural basis of catalytic activation in human splicing |
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Decoding and Recoding of mRNA Sequences by the Ribosome |
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Human lung virtual histology by multi-scale x-ray phase-contrast computed tomography |
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Fluorescence Spectroscopy in Planar Dielectric and Metallic Systems | | Chizhik AI, Ruhlandt D, Enderlein J | Photonic Quantum Technologies | 2023 | | |
In vitro and in vivo characterization of improved channelrhodopsin ChRmine variants for optogenetic activation of the auditory pathway | | Zerche M, Hunniford V, Witzke I, Wolf B, Mager T, Moser T | Laryngo-Rhino-Otologie | 2023 | | |
Characterization of novel channelrhodopsin variants for blue-light optogenetic activation of the auditory pathway | | Roos L, Garrido-Charles A, Wolf B, Kusch K, Mager T, Moser T | Laryngo-Rhino-Otologie | 2023 | | |
From emergency response to long-term management: the many faces of the endemic state of COVID-19 |
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Cytochrome c oxidase biogenesis – from translation to early assembly of the core subunit COX1 |
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Quick Adaptive Ternary Segmentation: An Efficient Decoding Procedure For Hidden Markov Models |
| Mösching A, Li H, Munk A | arXiv | 2023 | | |
N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing |
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An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes | | Dai Y, Ignatyeva N, (...), Ebert A | Circulation Research | 2023 | | |
Investigating human lung tissue by propagation-based phase-contrast X-ray tomography |
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ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts | | Rouvière JO, Salerno-Kochan A, (...), Jensen TH | Molecular Cell | 2023 | | |
Physiology of intracellular calcium buffering | | Eisner D, Neher E, Taschenberger H, Smith G | Physiological Reviews | 2023 | | |
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues |
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Convergence of Empirical Optimal Transport in Unbounded Settings |
| Staudt T, Hundrieser S | arXiv | 2023 | | |
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease |
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Targeting Biomolecular Condensation and Protein Aggregation against Cancer | | Silva JL, Foguel D, (...), de Oliveira GAP | Chemical Reviews | 2023 | | |
Mechanisms of inward transmembrane proton translocation | | Kovalev K, Tsybrov F, (...), Gordeliy V | Nature Structural & Molecular Biology | 2023 | | |
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease |
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Translation termination in human mitochondria – substrate specificity of mitochondrial release factors |
| Nadler F, Richter-Dennerlein R | Biological Chemistry | 2023 | | |
AI and protein structure and function in neurological disease: relevance to disease management | | Outeiro TF, Vieira TCRG | Nature Reviews Neurology | 2023 | | |
Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC) |
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Cryo-EM structures of lipidic fibrils of amyloid-β (1-40) |
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Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina | | Krüppel S, Khani MH, (...), Gollisch T | Journal of Neuroscience | 2023 | | |
Infomorphic networks: Locally learning neural networks derived from partial information decomposition |
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Hijacking of internal calcium dynamics by intracellularly residing rhodopsins |
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Flotillin-associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes |
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Modulating Secondary Structure Motifs through Photo‐labile Peptide Staples |
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Measuring sub-nanometer fluctuations at microsecond temporal resolution with metal-and graphene-induced energy transfer spectroscopy |
| Chen T, Karedla N, Enderlein J | bioRxiv | 2023 | | |
Vicious Twins: RyR2 Dysfunction and Structural Remodeling | | Voigt N, Seibertz F, Fakuade FE | Circulation Research | 2023 | | |
Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging |
| Markus MA, Ferrari DP, Alves F, Ramos-Gomes F | Biomedical Optics Express | 2023 | | |
Metal-induced energy transfer (MIET) imaging of cell surface engineering with multivalent DNA nanobrushes |
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Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing | | Michanski S, Kapoor R, (...), Wichmann C | EMBO reports | 2023 | | |
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto‐axonal target in late‐stage Parkinson's disease |
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Multiscale scanning with nuisance parameters |
| König C, Munk A, Werner F | arXiv | 2023 | | |
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome |
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Modulation of translational decoding by m6A modification of mRNA |
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Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis | | Monteiro Neto JR, Ribeiro GD, Magalhães RS, Follmer C, Outeiro TF, Eleutherio EC | Biochimica et Biophysica Acta-Molecular Basis of Disease | 2023 | | |
Structural conservation of antibiotic interaction with ribosomes | | Paternoga H, Crowe-McAuliffe C, (...), Wilson DN | Nature Structural & Molecular Biology | 2023 | | |
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies | | Chopra A, Outeiro TF | Brain | 2023 | | |
A viral ADP-ribosyltransferase attaches RNA chains to host proteins |
| Wolfram-Schauerte M, Pozhydaieva N, (...), Höfer K | Nature | 2023 | | |
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis |
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DNA-Based Optical Sensors for Forces in Cytoskeletal Networks | | Jayachandran C, Ghosh A, (...), Schmidt CF | ACS Applied Nano Materials | 2023 | | |
Bioengineering of a human innervated cardiac muscle model |
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Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine |
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A scalable clustering algorithm to approximate graph cuts |
| Suchan L, Li H, Munk A | arXiv | 2023 | | |
Unravelling ATP processing by the AAA+ protein p97 at the atomic level |
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En route to sound coding strategy for optical cochlear implants |
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Boosting of neural circuit chaos at the onset of collective oscillations |
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N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody |
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Segment Anything for Microscopy |
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Intracellular mechanical fingerprint reveals cell type specific mechanical tuning |
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Doubling the resolution of single-molecule localization microscopy with image scanning microscopy |
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Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development |
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Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE) | | Oppermann Peixoto D, Bittencourt RR, (...), Pens Gelain D | Journal of Neurochemistry | 2023 | | |
Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis |
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Evaluating the association of biallelic OGDHL variants with significant phenotypic heterogeneity |
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Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression |
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Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis? |
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Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase | | Egbert JR, Silbern I, (...), Jaffe LA | Biology of Reproduction | 2023 | | |
4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applications |
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Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm |
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The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice |
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Approaching automation of multiple instance orchestration of the menoci web portal |
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Diversity matters - extending sound intensity coding by inner hair cells via heterogeneous synapses |
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Cardiac multiscale bioimaging: from nano- through micro- to mesoscales |
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Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities |
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GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases |
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Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative Analysis | | Oleksiievets N, Mathew C, (...), Enderlein J | Nano Letters | 2022 | | |
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial |
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Remote control of the heart and beyond | | Zimmermann W | Science | 2022 | | |
A Mathematical Model for Electrical Activity in Pig Atrial Tissue |
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Allosteric control of Ubp6 and the proteasome via a bidirectional switch |
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WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly | | Bögershausen N, Krawczyk HE, (...), Wollnik B | Human Mutation | 2022 | | |
Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration |
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Statistical spatial analysis for cryo-electron tomography |
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Sequence determinants of human gene regulatory elements |
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Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control |
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Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants |
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Is there an unmet medical need for improved hearing restoration? | | Wolf BJ, Kusch K, (...), Moser T | EMBO Molecular Medicine | 2022 | | |
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function |
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Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX |
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Structure of a backtracked hexasomal intermediate of nucleosome transcription | | Farnung L, Ochmann M, Garg G, Vos SM, Cramer P | Molecular Cell | 2022 | | |
Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology |
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HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation |
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Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43 |
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Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory |
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A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data |
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Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice |
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α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals |
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The 3D structure of lipidic fibrils of α-synuclein |
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Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes |
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Production of Recombinant Alpha-Synuclein: Still No Standardized Protocol in Sight |
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Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues | | Santos GL, DeGrave AN, (...), Lutz S | Biomaterials Advances | 2022 | | |
Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3 |
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A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming |
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JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species | | Santos CC, Cardim-Pires TR, (...), Silva VDA | Neurotoxicity Research | 2022 | | |
Multiscale architecture: Mechanics of composite cytoskeletal networks |
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Combined optical fluorescence microscopy andX-ray tomography reveals substructures in cellnuclei in 3D |
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DNA-PAINT MINFLUX nanoscopy |
| Ostersehlt LM, Jans DC, (...), Jakobs S | Nature Methods | 2022 | | |
IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter |
| Katsenelson M, Shapira I, (...), Slutsky I | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 |
| Gregor C | Scientific Reports | 2022 | | |
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis |
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Interdomain Dynamics via Paramagnetic NMR on the Highly Flexible Complex Calmodulin/Munc13-1 |
| Karschin N, Becker S, Griesinger C | Journal of the American Chemical Society | 2022 | | |
The murine male reproductive organ at a glance: Three‐dimensional insights and virtual histology using label‐free light sheet microcopy |
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Ectosomes and exosomes modulate neuronal spontaneous activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Proteomics | 2022 | | |
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes |
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Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II |
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Quantitative Magnetic Resonance Imaging by Nonlinear Inversion of the Bloch Equations |
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A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry |
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A Sequential Two-Step Priming Scheme Reproduces Diversity in Synaptic Strength and Short-Term Plasticity |
| Lin K, Taschenberger H, Neher E | Social Science Research Network | 2022 | | |
A Variational View on Statistical Multiscale Estimation | | Haltmeier M, Li H, Munk A | Annual Review of Statistics and Its Application | 2022 | | |
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
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Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts |
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Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients |
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Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice |
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Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden |
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MRI Reconstruction via Data Driven Markov Chain with Joint Uncertainty Estimation |
| Luo G, Heide M, Uecker M | arXiv | 2022 | | |
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain |
| Liu T, Stephan T, (...), Chen Z | bioRxiv | 2022 | | |
Retinal Encoding of Natural Scenes | | Karamanlis D, Schreyer HM, Gollisch T | Annual Review of Vision Science | 2022 | | |
Synaptic transmission at the vestibular hair cells of amniotes | | Mukhopadhyay M, Pangrsic T | Molecular and Cellular Neuroscience | 2022 | | |
The Statistics of Circular Optimal Transport |
| Hundrieser S, Klatt M, Munk A | Forum for Interdisciplinary Mathematics | 2022 | | |
Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs |
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Whole genome sequencing for newborns—The devil is in the details |
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GGPS1‐associated muscular dystrophy with and without hearing loss |
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Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study |
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Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease |
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Electrophysiological Characterization of Microbial Rhodopsins by Patch-Clamp Experiments | | Mager T | Methods in Molecular Biology | 2022 | | |
Imaging of Autonomous Bioluminescence Emission From Single Mammalian Cells | | Gregor C | Methods in Molecular Biology | 2022 | | |
A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity |
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Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices |
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Expansion microscopy at one nanometer resolution |
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Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules |
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Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain |
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Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA A Rs and cytosolic gephyrin aggregation |
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A sequential two-step priming scheme reproduces diversity in synaptic strength and short-term plasticity |
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Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina |
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From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms |
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Structure of angiogenin dimer bound to double-stranded RNA |
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Roadmap for Optical Tweezers |
| Volpe G, Maragò OM, (...), Swartzlander GA | arXiv | 2022 | | |
Bridging the gap between presynaptic hair cell function and neural sound encoding |
| Jaime Tobón LM, Moser T | bioRxiv | 2022 | | |
From LUVs to GUVs - how to cover micrometer-sized pores with membranes |
| Kramer K, Sari M, (...), Steinem C | ChemRxiv | 2022 | | |
Aneuploidy in mammalian oocytes and the impact of maternal ageing | | Charalambous C, Webster A, Schuh M | Nature Reviews Molecular Cell Biology | 2022 | | |
Graded optogenetic activation of the auditory pathway for neural network analysis and hearing restoration |
| Mittring A, Moser T, Huet A | bioRxiv | 2022 | | |
Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism |
| Wohlfarter Y, Eidelpes R, (...), Keller MA | Cellular and Molecular Life Sciences | 2022 | | |
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils |
| Antonschmidt L, Matthes D, (...), Andreas LB | Nature Communications | 2022 | | |
Deep, deep learning with BART |
| Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker M | Magnetic Resonance in Medicine | 2022 | | |
Extracellular Matrix Recycling as a Novel Plasticity Mechanism With a Potential Role in Disease |
| Dankovich TM, Rizzoli SO | Frontiers in Cellular Neuroscience | 2022 | | |
Impact of native-like lipid membranes on the architecture and contractility of actomyosin networks |
| Liebe NL, Mey I, Vuong L, Geil B, Janshoff A, Steinem C | bioRxiv | 2022 | | |
There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments |
| Rapedius M, Obergrussberger A, (...), Fertig N | Frontiers in Molecular Neuroscience | 2022 | | |
In silico modeling for personalized stenting in aortic coarctation |
| Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker M | Engineering Applications of Computational Fluid Mechanics | 2022 | | |
A quantitative fluorescence-based approach to study mitochondrial protein import |
| Jain N, Gomkale R, Bernhard O, Rehling P, Cruz-Zaragoza LD | bioRxiv | 2022 | | |
Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy |
| Shahriyari M, Islam MR, (...), Tiburcy M | Journal of Cachexia, Sarcopenia and Muscle | 2022 | | |
Imaging of arrhythmia: Real-time cardiac magnetic resonance imaging in atrial fibrillation |
| Laubrock K, von Loesch T, (...), Unterberg-Buchwald C | European Journal of Radiology Open | 2022 | | |
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control |
| Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R | Nature Communications | 2022 | | |
Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous Environment | | Corbet BP, Schlüter JM, Cotroneo ER, Crespi S, Simeth NA | European Journal of Organic Chemistry | 2022 | | |
Inflammation and vascular remodeling in COVID-19 hearts |
| Werlein C, Ackermann M, (...), Jonigk D | Angiogenesis | 2022 | | |
Cochlear Hair Cell Innervation is Dependent on a Modulatory Function of Semaphorin‐3A | | Cantu‐Guerra HL, Papazian MR, (...), Coate TM | Developmental Dynamics | 2022 | | |
Kantorovich–Rubinstein Distance and Barycenter for Finitely Supported Measures: Foundations and Algorithms |
| Heinemann F, Klatt M, Munk A | Applied Mathematics & Optimization | 2022 | | |
Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment | | Cheng S, Altmeppen G, (...), Schuh M | Science | 2022 | | |
Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane |
| Swaih AM, Breda C, (...), Giorgini F | Biomedicines | 2022 | | |
Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling |
| Paulke N, Amlaz S, (...), Brandenburg S | European Heart Journal | 2022 | | |
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita |
| Schnabel F, Schuler E, (...), Yigit G | Researchsquare | 2022 | | |
Graphene-Induced Energy Transfer for Quantitative Membrane Biophysics at Sub-Nanometer Resolution |
| Chen T, Ghosh A, Enderlein J | arXiv | 2022 | | |
Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag |
| Steyer AM, Buscham TJ, (...), Werner HB | Glia | 2022 | | |
Unbalanced Kantorovich-Rubinstein distance and barycenter for finitely supported measures: A statistical perspective |
| Heinemann F, Klatt M, Munk A | arXiv | 2022 | | |
New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain |
| Weninger G, Lehnart SE | Journal of Cellular Signaling | 2022 | | |
Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones |
| Tan C, de Nola G, (...), Kaeser PS | eLife | 2022 | | |
Structures of transcription preinitiation complex engaged with the +1 nucleosome |
| Wang H, Schilbach S, Ninov M, Urlaub H, Cramer P | Nature Structural & Molecular Biology | 2022 | | |
Regulation of the mammalian-brain V-ATPase through ultraslow mode-switching | | Kosmidis E, Shuttle CG, (...), Stamou D | Nature | 2022 | | |
Editorial: Cardiac optogenetics: Using light to observe and excite the heart |
| Bruegmann T, Smith GL, Lehnart SE | Frontiers in Physiology | 2022 | | |
Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation | | Voigt N, Maack C, Pronto JRD | Journal of the American College of Cardiology | 2022 | | |
Randomized Wasserstein Barycenter Computation: Resampling with Statistical Guarantees | | Heinemann F, Munk A, Zemel Y | SIAM Journal on Mathematics of Data Science | 2022 | | |
Sampling effects and measurement overlap can bias the inference of neuronal avalanches |
| Pinheiro Neto J, Spitzner FP, Priesemann V | PLOS Computational Biology | 2022 | | |
Recent Advances in Modeling Mitochondrial Cardiomyopathy Using Human Induced Pluripotent Stem Cells |
| Pavez-Giani MG, Cyganek L | Frontiers in Cell and Developmental Biology | 2022 | | |
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp |
| Rosholm KR, Badone B, (...), Bell DC | Frontiers in Molecular Neuroscience | 2022 | | |
Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion |
| Lāce I, Cotroneo ER, Hesselbarth N, Simeth NA | Journal of Peptide Science | 2022 | | |
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis |
| Galbusera R, Bahn E, (...), Granziera C | Brain Pathology | 2022 | | |
Skeletal Class III Malocclusion Is Associated with ADAMTS2 Variants and Reduced Expression in a Familial Case |
| Yao S, Zhou X, (...), Pan Y | International Journal of Molecular Sciences | 2022 | | |
Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli |
| Shahidi N, Rozenblit F, (...), Gollisch T | bioRxiv | 2022 | | |
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse |
| Hain PJH, Moser T | bioRxiv | 2022 | | |
Tackling the Dynamic Range Problem of Hearing: Diverse Hair Cell Synapses Enable Broad Neural Sound Intensity Coding |
| Jaime Tobón LM, Moser T | Social Science Research Network | 2022 | | |
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II |
| Rengachari S, Schilbach S, (...), Cramer P | Nature Structural & Molecular Biology | 2022 | | |
Tailoring Cardiac Synthetic Transcriptional Modulation Towards Precision Medicine |
| Schoger E, Lelek S, Panáková D, Zelarayán LC | Frontiers in Cardiovascular Medicine | 2022 | | |
Free‐breathing myocardial T1 mapping using inversion‐recovery radial FLASH and motion‐resolved model‐based reconstruction |
| Wang X, Rosenzweig S, (...), Uecker M | Magnetic Resonance in Medicine | 2022 | | |
Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum |
| Schmidt J, Dreha-Kulaczewski S, (...), Wollnik B | Frontiers in Cell and Developmental Biology | 2022 | | |
The Synaptic Extracellular Matrix: Long-Lived, Stable, and Still Remarkably Dynamic |
| Dankovich TM, Rizzoli SO | Frontiers in Synaptic Neuroscience | 2022 | | |
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity |
| Stewart H, Lu Y, (...), Firth AE | bioRxiv | 2022 | | |
The 3D structure of lipidic fibrils of α-synuclein |
| Frieg B, Antonschmidt L, (...), Schröder GF | Nature Communications | 2022 | | |
Mono- and Intralink Filter (Mi-Filter) To Reduce False Identifications in Cross-Linking Mass Spectrometry Data |
| Chen X, Sailer C, (...), Stengel F | Analytical Chemistry | 2022 | | |
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain |
| Liu T, Stephan T, (...), Chen Z | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores |
| Gregor C, Grimm F, Rehman J, Wurm CA, Egner A | bioRxiv | 2022 | | |
Cotranslational Biogenesis of Membrane Proteins in Bacteria |
| Mercier E, Wang X, Bögeholz LAK, Wintermeyer W, Rodnina MV | Frontiers in Molecular Biosciences | 2022 | | |
Expanding the spectrum of EEF1D neurodevelopmental disorders: Biallelic variants in the Guanine Exchange Domain | | Averdunk L, Al‐Thihli K, (...), Wieczorek D | Clinical Genetics | 2022 | | |
On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants |
| Helke C, Reinhardt M, (...), Reuter D | Materials | 2022 | | |
Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities | | Schaeper JJ, Liberman MC, Salditt T | Developments in X-Ray Tomography XIV | 2022 | | |
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
| Koss DJ, Erskine D, (...), Outeiro TF | Acta Neuropathologica Communications | 2022 | | |
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | eLife | 2022 | | |
From guide to guard—activation mechanism of the stress-sensing chaperone Get3 |
| Ulrich K, Farkas Á, Chan O, Katamanin O, Schwappach B, Jakob U | Molecular Cell | 2022 | | |
A Measure of the Complexity of Neural Representations based on Partial Information Decomposition |
| Ehrlich DA, Schneider AC, Priesemann V, Wibral M, Makkeh A | arXiv | 2022 | | |
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease | | Hatton C, Ghanem SS, (...), Erskine D | Brain | 2022 | | |
The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation |
| Kleiber N, Lemus-Diaz N, (...), Bohnsack MT | Nature Communications | 2022 | | |
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes |
| Brandenburg S, Pawlowitz J, (...), Lehnart SE | Journal of Molecular and Cellular Cardiology | 2022 | | |
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells |
| Oleksiievets N, Sargsyan Y, (...), Tsukanov R | Communications Biology | 2022 | | |
Age-dependent structural reorganization of utricular ribbon synapses |
| Michanski S, Henneck T, (...), Wichmann C | bioRxiv | 2022 | | |
The Role of Junctophilin Proteins in Cellular Function |
| Lehnart SE, Wehrens XH | Physiological Reviews | 2022 | | |
On the Uniqueness of Kantorovich Potentials |
| Staudt T, Hundrieser S, Munk A | arXiv | 2022 | | |
A Molecular Pump Facilitates Mechanical Adsorption Away from Equilibrium | | Simeth NA | Angewandte Chemie-International Edition | 2022 | | |
Dystrophin is a mechanical tension modulator |
| Hofemeier AD, Muenker TM, (...), Betz T | bioRxiv | 2022 | | |
Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria |
| Chojnacka KJ, Elancheliyan P, (...), Chacińska A | Molecular Biology of the Cell | 2022 | | |
Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Parkinsons Disease | 2022 | | |
Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses |
| Michanski S, Kapoor R, (...), Wichmann C | bioRxiv | 2022 | | |
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells |
| Vasili E, Dominguez-Meijide A, (...), Outeiro TF | Molecular Neurobiology | 2022 | | |
Mechanism of spindle pole organization and instability in human oocytes | | So C, Menelaou K, (...), Schuh M | Science | 2022 | | |
Structural basis for safe and efficient energy conversion in a respiratory supercomplex |
| Kao W, Ortmann de Percin Northumberland C, (...), Hunte C | Nature Communications | 2022 | | |
Real‐time radial tagging for quantification of left ventricular torsion | | Mohammadi E, Nasiraei‐Moghaddam A, Uecker M | Magnetic Resonance in Medicine | 2022 | | |
Rethinking opsins |
| Feuda R, Menon AK, Göpfert MC | Molecular Biology and Evolution | 2022 | | |
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures |
| Gönenc II, Wolff A, (...), Wollnik B | Human Molecular Genetics | 2022 | | |
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds |
| Saha I, Yuste-Checa P, (...), Hipp MS | bioRxiv | 2022 | | |
Indole derivatives as core structural motifs in molecular organic photoactuators |
| Simeth NA, Crespi S | | 2022 | | |
Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy |
| Wegner W, Steffens H, Gregor C, Wolf F, Willig KI | eLife | 2022 | | |
Empirical Optimal Transport between Different Measures Adapts to Lower Complexity |
| Hundrieser S, Staudt T, Munk A | arXiv | 2022 | | |
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation |
| Torres-Garcia L, P. Domingues JM, (...), Li J | Scientific Reports | 2022 | | |
A new form of axonal pathology in a spinal model of neuromyelitis optica |
| Herwerth M, Kenet S, (...), Misgeld T | Brain | 2022 | | |
Phenotypic spectrum of BLM and RMI1–related Bloom syndrome |
| Gönenc II, Elcioglu NH, (...), Wollnik B | Clinical Genetics | 2022 | | |
Deep, Deep Learning with BART |
| Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker M | arXiv | 2022 | | |
A Unifying Approach to Distributional Limits for Empirical Optimal Transport |
| Hundrieser S, Klatt M, Staudt T, Munk A | arXiv | 2022 | | |
White matter integrity in mice requires continuous myelin synthesis at the inner tongue |
| Meschkat M, Steyer AM, (...), Möbius W | Nature Communications | 2022 | | |
MemBrain: A Deep Learning-aided Pipeline for Automated Detection of Membrane Proteins in Cryo-electron Tomograms |
| Lamm L, Righetto RD, (...), Engel BD | bioRxiv | 2022 | | |
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease |
| Shomroni O, Sitte M, (...), Salinas G | Scientific Reports | 2022 | | |
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3 |
| Upmanyu N, Jin J, (...), Sambandan S | Neuron | 2022 | | |
Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene |
| Pater JA, Penney C, (...), Young T | Human Genetics | 2022 | | |
Modeling charge separation in charged nanochannels for single-molecule electrometry | | Enderlein J, Sakhapov D, Gregor I, Croci M, Karedla N | Journal of Chemical Physics | 2022 | | |
Methods for multiscale structural and functional analysis of the mammalian cochlea | | Vogl C, Neef J, Wichmann C | Molecular and Cellular Neuroscience | 2022 | | |
Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition |
| Farzadfard A, König A, (...), Otzen DE | Journal of Biological Chemistry | 2022 | | |
Extracellular alpha-synuclein: Sensors, receptors, and responses |
| Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF | Neurobiology of Disease | 2022 | | |
Selective optogenetic control of Gq signaling using human Neuropsin |
| Wagdi A, Malan D, (...), Bruegmann T | Nature Communications | 2022 | | |
Boosting of neural circuit chaos at the onset of collective oscillations |
| Palmigiano A, Engelken R, Wolf F | bioRxiv | 2022 | | |
Roles and dynamics of 3-methylcytidine in cellular RNAs |
| Bohnsack KE, Kleiber N, Lemus-Diaz N, Bohnsack MT | Trends in Biochemical Sciences | 2022 | | |
Measuring photophysical transition rates with fluorescence correlation spectroscopy and antibunching |
| Sakhapov D, Gregor I, Karedla N, Enderlein J | arXiv | 2022 | | |
Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system |
| Calapai A, Cabrera-Moreno J, Moser T, Jeschke M | Nature Communications | 2022 | | |
Optimal transfer functions for bandwidth-limited imaging |
| Stallinga S, Radmacher N, Delon A, Enderlein J | Physical Review Research | 2022 | | |
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains |
| Peña-Díaz S, Pujols J, (...), Ventura S | Journal of Biological Chemistry | 2022 | | |
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation – A proof-of-concept study | | Jebran A, Tiburcy M, (...), Zimmermann W | Journal of Molecular and Cellular Cardiology | 2022 | | |
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS | | Vincenti I, Page N, (...), Merkler D | Science Translational Medicine | 2022 | | |
Statistical analysis of random objects via metric measure Laplacians |
| Mordant G, Munk A | arXiv | 2022 | | |
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration |
| Luebben AV, Bender D, (...), Steinfeld R | Science Advances | 2022 | | |
The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible |
| Cassotta M, Geerts H, (...), Hogberg HT | ALTEX-Alternatives to Animal Experimentation | 2022 | | |
Seeded binary segmentation: a general methodology for fast and optimal changepoint detection |
| Kovács S, Bühlmann P, Li H, Munk A | Biometrika | 2022 | | |
Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance |
| Ding Y, Korchak S, (...), Glöggler S | Chemistry–Methods | 2022 | | |
Free-Breathing Liver Fat, R₂* and B₀ Field Mapping Using Multi-Echo Radial FLASH and Regularized Model-Based Reconstruction | | Tan Z, Unterberg-Buchwald C, (...), Uecker M | IEEE Transactions on Medical Imaging | 2022 | | |
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons |
| Riemenschneider H, Guo Q, (...), Edbauer D | EMBO Reports | 2022 | | |
Statistical Methods for Minimax Estimation in Linear Models with Unknown Design Over Finite Alphabets | | Behr M, Munk A | SIAM Journal on Mathematics of Data Science | 2022 | | |
Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice |
| Bali B, Gruber-Dujardin E, Kusch K, Rankovic V, Moser T | Life Science Alliance | 2022 | | |
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy |
| Jung P, Seibertz F, (...), Voigt N | Basic Research in Cardiology | 2022 | | |
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | bioRxiv | 2022 | | |
In silico modeling for personalized stenting in aortic coarctation |
| Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker M | arXiv | 2022 | | |
IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress |
| Nanadikar M, Leon AV, (...), Katschinski D | Researchsquare | 2022 | | |
Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea |
| Garrido-Charles A, Huet A, (...), Gorostiza P | Journal of the American Chemical Society | 2022 | | |
Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway |
| Farkas A, Urlaub H, Bohnsack KE, Schwappach B | Journal of Cell Biology | 2022 | | |
Identification and optimization of channelrhodopsin variants for optogenetic hearing restoration |
| Zerche M, Moser T, Mager T | Laryngo-Rhino-Otologie 2022 | 2022 | | |
In vivo investigation of f-Chrimson variants for optogenetic hearing restoration |
| Wrobel C, Zerche M, Kusch K, Mager T, Moser T | Laryngo-Rhino-Otologie 2022 | 2022 | | |
Distribution of Distances based Object Matching: Asymptotic Inference | | Weitkamp CA, Proksch K, Tameling C, Munk A | Journal of the American Statistical Association | 2022 | | |
Excited state lifetime modulation in semiconductor nanocrystals for super-resolution imaging |
| Ghosh S, Hollingsworth J, Gallea JI, Majumder S, Enderlein J, Chizhik A | Nanotechnology | 2022 | | |
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair | | Tiburcy M, Meyer T, Satin P, Zimmermann W | Methods in Molecular Biology | 2022 | | |
A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution | | Elizarova S, Chouaib AA, (...), Daniel JA | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
| Yudovich S, Marzouqe A, (...), Weiss S | Biophysical Journal | 2022 | | |
Background calcium influx in arrhythmia: lead actor or extra? |
| Fakuade FE, Fauconnier J, Voigt N | Journal of Physiology-London | 2022 | | |
The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease | | Garg P, Maass F, (...), Bähr M | Molecular and Cellular Neuroscience | 2022 | | |
Not the classical serendipity: does doxapram treat atrial fibrillation? |
| Liutkute A, Brundel BJ, Voigt N | Cardiovascular Research | 2022 | | |
Retinal receptive-field substructure: scaffolding for coding and computation |
| Zapp SJ, Nitsche S, Gollisch T | Trends in Neurosciences | 2022 | | |
Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome |
| Schmidt J, Bremmer F, Brockmann K, Kaulfuß S, Wollnik B | Clinical Genetics | 2022 | | |
An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry |
| Kabatas Glowacki S, Agüi-Gonzalez P, (...), Rizzoli SO | Chemical Communications | 2022 | | |
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
| Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H | Nucleic Acids Research | 2022 | | |
Effects of cryo-EM cooling on structural ensembles |
| Bock LV, Grubmüller H | Nature Communications | 2022 | | |
Isotropic three-dimensional dual-color super-resolution microscopy with metal-induced energy transfer |
| Thiele JC, Jungblut M, (...), Enderlein J | Science Advances | 2022 | | |
Measuring Photophysical Transition Rates with Fluorescence Correlation Spectroscopy and Antibunching | | Sakhapov D, Gregor I, Karedla N, Enderlein J | Journal of Physical Chemistry Letters | 2022 | | |
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells |
| Xiong L, Tolen EA, (...), Schöler HR | eLife | 2022 | | |
Structural and mechanistic basis of RNA processing by protein-only ribonuclease P enzymes |
| Bhatta A, Hillen HS | Trends in Biochemical Sciences | 2022 | | |
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes |
| Weninger G, Pochechueva T, (...), Lehnart SE | Scientific Reports | 2022 | | |
Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations |
| Buratti FA, Boeffinger N, (...), Fernández CO | Protein Science | 2022 | | |
Distinct roles of the meningeal layers in CNS autoimmunity | | Merlini A, Haberl M, (...), Odoardi F | Nature Neuroscience | 2022 | | |
MemBrain: A Deep Learning-aided Pipeline for Detection of Membrane Proteins in Cryo-electron Tomograms | | Lamm L, Righetto RD, (...), Engel BD | Computer Methods and Programs in Biomedicine | 2022 | | |
Rapid multi-plane phase-contrast microscopy reveals torsional dynamics in flagellar motion |
| Mojiri S, Isbaner S, (...), Enderlein J | Biomedical Optics Express | 2021 | | |
Tejaas: reverse regression increases power for detecting trans-eQTLs |
| Banerjee S, Simonetti FL, (...), Söding J | Genome Biology | 2021 | | |
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis |
| Kabinger F, Stiller C, (...), Cramer P | bioRxiv | 2021 | | |
Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes |
| Antonschmidt L, Dervişoğlu R, (...), Griesinger C | Science Advances | 2021 | | |
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 |
| Fianu I, Dienemann C, Aibara S, Schilbach S, Cramer P | Communications Biology | 2021 | | |
α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease |
| Stuendl A, Kraus T, (...), Schneider A | Movement Disorders | 2021 | | |
Multi-label in vivo STED microscopy by parallelized switching of reversibly switchable fluorescent proteins |
| Willig KI, Wegner W, Müller A, Calvet-Fournier V, Steffens H | Cell Reports | 2021 | | |
Transmembrane β‐peptide helices as molecular rulers at the membrane surface |
| Kloos M, Sharma A, Enderlein J, Diederichsen U | Journal of Peptide Science | 2021 | | |
Graphene- and metal-induced energy transfer for single-molecule imaging and live-cell nanoscopy with (sub)-nanometer axial resolution | | Ghosh A, Chizhik AI, Karedla N, Enderlein J | Nature Protocols | 2021 | | |
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity |
| Steffens H, Mott AC, (...), Willig KI | Science Advances | 2021 | | |
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening | | Schilbach S, Aibara S, Dienemann C, Grabbe F, Cramer P | Cell | 2021 | | |
Structural basis of nucleosome transcription mediated by Chd1 and FACT |
| Farnung L, Ochmann M, Engeholm M, Cramer P | Nature Structural & Molecular Biology | 2021 | | |
Radiative Rate Modulation Reveals Near‐Unity Quantum Yield of Graphene Quantum Dots |
| Ghosh S, Oleksiievets N, Enderlein J, Chizhik AI | Advanced Optical Materials | 2021 | | |
Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis |
| Bergner CG, Genc N, (...), Stadelmann C | Glia | 2021 | | |
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1 tm1Kds mice and X-linked adrenoleukodystrophy patients |
| Kettwig M, Klemp H, (...), Gärtner J | Journal of Inherited Metabolic Disease | 2021 | | |
Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases |
| Koss DJ, Campesan S, Giorgini F, Outeiro TF | Movement Disorders | 2021 | | |
Analysis of patchclamp recordings: model-free multiscale methods and software |
| Pein F, Eltzner B, Munk A | European Biophysics Journal | 2021 | | |
Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome |
| Epple R, Krüger D, (...), Fischer A | Molecular Neurobiology | 2021 | | |
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex | | Huang B, Guo Q, (...), Fernández-Busnadiego R | Structure | 2021 | | |
Pore-Spanning Plasma Membranes Derived from Giant Plasma Membrane Vesicles | | Teiwes NK, Mey I, Baumann PC, Strieker L, Unkelbach U, Steinem C | ACS Applied Materials & Interfaces | 2021 | | |
In situ architecture of neuronal α-Synuclein inclusions |
| Trinkaus VA, Riera-Tur I, (...), Fernández-Busnadiego R | Nature Communications | 2021 | | |
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
| Oberbeckmann E, Niebauer V, (...), Korber P | Nature Communications | 2021 | | |
IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter |
| Katsenelson M, Shapira I, (...), Slutsky I | bioRxiv | 2021 | | |
3D virtual Histopathology of Cardiac Tissue from Covid-19 Patients based on Phase-Contrast X-ray Tomography |
| Reichardt M, Jensen PM, (...), Salditt T | bioRxiv | 2021 | | |
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology |
| Kargapolova Y, Rehimi R, (...), Papantonis A | Nature Communications | 2021 | | |
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy | | Xu H, Wali R, (...), Ebert A | FEBS Letters | 2021 | | |
MINSTED fluorescence localization and nanoscopy |
| Weber M, Leutenegger M, (...), Hell SW | Nature Photonics | 2021 | | |
Structures of mammalian RNA polymerase II pre-initiation complexes | | Aibara S, Schilbach S, Cramer P | Nature | 2021 | | |
Astrocytes control the spiking of mouse visual cortex layer 5 pyramidal neurons |
| Sundaram SM, Garg P, Leßlich HM, Mathivanan S | Journal of Physiology-London | 2021 | | |
Multiple haplotype reconstruction from allele frequency data | | Pelizzola M, Behr M, Li H, Munk A, Futschik A | Nature Computational Science | 2021 | | |
Physics-based reconstruction methods for magnetic resonance imaging |
| Wang X, Tan Z, Scholand N, Roeloffs V, Uecker M | Philosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences | 2021 | | |
Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons |
| Riemenschneider H, Guo Q, (...), Edbauer D | bioRxiv | 2021 | | |
Sequence determinants of human gene regulatory elements |
| Sahu B, Hartonen T, (...), Taipale J | bioRxiv | 2021 | | |
RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse |
| Butola T, Alvanos T, (...), Moser T | bioRxiv | 2021 | | |
Dimeric form of SARS-CoV-2 polymerase |
| Jochheim FA, Tegunov D, (...), Cramer P | bioRxiv | 2021 | | |
A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites |
| Elizarova S, Chouaib A, (...), Daniel J | bioRxiv | 2021 | | |
Cryo-electron tomography of native Drosophila tissues vitrified by plunge freezing |
| Bäuerlein FJ, Pastor-Pareja JC, Fernández-Busnadiego R | bioRxiv | 2021 | | |
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
| Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H | bioRxiv | 2021 | | |
Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain |
| Weish P, Lazaro DF, (...), Outeiro TF | bioRxiv | 2021 | | |
Instant three color multi-plane fluorescence microscopy |
| Gregor I, Butkevich E, Enderlein J, Mojiri S | bioRxiv | 2021 | | |
Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea |
| Garrido-Charles A, Huet A, (...), Gorostiza P | bioRxiv | 2021 | | |
Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy |
| Grabner CP, Jansen I, (...), Moser T | bioRxiv | 2021 | | |
Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
| Schaffner SL, Wassouf Z, (...), Kobor MS | bioRxiv | 2021 | | |
Structure of a transcribing RNA polymerase II–U1 snRNP complex | | Zhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer P | Science | 2021 | | |
A DNA-based optical force sensor for live-cell applications | | Jayachandran C, Ghosh A, (...), Schmidt CF | bioRxiv | 2021 | | |
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci |
| Kyryachenko S, Georges A, (...), Bouatia-Naji N | Circulation Research | 2021 | | |
Exercise Stress Real-Time Cardiac Magnetic Resonance Imaging for Noninvasive Characterization of Heart Failure With Preserved Ejection Fraction |
| Backhaus SJ, Lange T, (...), Schuster A | Circulation | 2021 | | |
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity |
| Medina L, González-Lizárraga F, (...), Socias SB | Frontiers in Aging Neuroscience | 2021 | | |
MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile |
| Jacinto S, Guerreiro P, (...), Outeiro TF | Frontiers in Cellular Neuroscience | 2021 | | |
Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants |
| Huet AT, Dombrowski T, Rankovic V, Thirumalai A, Moser T | Frontiers in Molecular Neuroscience | 2021 | | |
Posterior analysis of n in the binomial (n,p) problem with both parameters unknown -- with applications to quantitative nanoscopy |
| Schmidt-Hieber J, Schneider LF, Staudt T, Krajina A, Aspelmeier T, Munk A | arXiv | 2021 | | |
The ultrametric Gromov-Wasserstein distance |
| Mémoli F, Munk A, Wan Z, Weitkamp C | arXiv | 2021 | | |
Frame-constrained total variation regularization for white noise regression |
| del Álamo M, Li H, Munk A | Annals of Statistics | 2021 | | |
The Statistics of Circular Optimal Transport |
| Hundrieser S, Klatt M, Munk A | arXiv | 2021 | | |
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 | | Gregor C | bioRxiv | 2021 | | |
Limit Distributions and Sensitivity Analysis for Entropic Optimal Transport on Countable Spaces |
| Hundrieser S, Klatt M, Munk A | arXiv | 2021 | | |
Transport Dependency: Optimal Transport Based Dependency Measures |
| Nies TG, Staudt T, Munk A | arXiv | 2021 | | |
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state |
| Yigit G, Sheffer R, (...), Brockmann K | Journal of Medical Genetics | 2021 | | |
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines | | Helm MS, Dankovich TM, (...), Rizzoli SO | Nature Neuroscience | 2021 | | |
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein |
| Martinez Hernandez A, Silbern I, (...), Eichele G | Frontiers in Neuroscience | 2021 | | |
Oct4 primarily controls enhancer activity rather than accessibility |
| Xiong L, Tolen EA, (...), Schöler HR | bioRxiv | 2021 | | |
Posterior analysis of n in the binomial (n,p) problem with both parameters unknown—with applications to quantitative nanoscopy |
| Schmidt-Hieber J, Schneider LF, Staudt T, Krajina A, Aspelmeier T, Munk A | Annals of Statistics | 2021 | | |
Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils |
| Joppe KDn, Tatenhorst L, (...), Lingor P | Journal of Neurochemistry | 2021 | | |
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling |
| Hillen HS, Lavdovskaia E, (...), Richter-Dennerlein R | Nature Communications | 2021 | | |
Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling |
| Silbern I, Pan K, (...), Jahn R | Molecular & Cellular Proteomics | 2021 | | |
What is resolution? A statistical minimax testing perspective on superresolution microscopy |
| Kulaitis G, Munk A, Werner F | Annals of Statistics | 2021 | | |
Structure of the human Mediator–RNA polymerase II pre-initiation complex | | Rengachari S, Schilbach S, Aibara S, Dienemann C, Cramer P | Nature | 2021 | | |
Structural and functional insights into human tRNA guanine transgylcosylase | | Sievers K, Welp L, Urlaub H, Ficner R | RNA Biology | 2021 | | |
Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies |
| Iqbal M, Maroofian R, (...), Yigit G | Genetics in Medicine | 2021 | | |
isoSTED microscopy with water-immersion lenses and background reduction | | Siegmund R, Werner F, Jakobs S, Geisler C, Egner A | Biophysical Journal | 2021 | | |
Statistical spatial analysis for cryo-electron tomography |
| Martinez-Sanchez A, Baumeister W, Lučić V | arXiv | 2021 | | |
Photophysical properties and fluorescence lifetime imaging of exfoliated near-infrared fluorescent silicate nanosheets |
| Selvaggio G, Weitzel M, (...), Kruss S | Nanoscale Advances | 2021 | | |
CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation |
| Sadredini M, Haugsten Hansen M, (...), Stokke MK | American Journal of Physiology-Heart and Circulatory Physiology | 2021 | | |
Allosteric transcription stimulation by RNA polymerase II super elongation complex | | Chen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer P | Molecular Cell | 2021 | | |
Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells |
| Brás IC, Khani MH, (...), Outeiro TF | bioRxiv | 2021 | | |
Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors |
| Cretu C, Gee P, (...), Pena V | Nature Communications | 2021 | | |
MFSD2A-associated primary microcephaly - Expanding the clinical and mutational spectrum of this ultra-rare disease | | Khuller K, Yigit G, (...), Kuechler A | European Journal of Medical Genetics | 2021 | | |
Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging |
| Raja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh A | bioRxiv | 2021 | | |
Advanced fluorescence correlation spectroscopy for studying biomolecular conformation |
| Ghosh A, Enderlein J | Current Opinion in Structural Biology | 2021 | | |
Organs-on-chip models for cardiovascular drug development |
| Zimmermann W | Cardiovascular Research | 2021 | | |
Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression |
| Schoger E, Zimmermann W, Cyganek L, Zelarayán LC | Stem Cell Research | 2021 | | |
The structure of a dimeric form of SARS-CoV-2 polymerase |
| Jochheim FA, Tegunov D, (...), Cramer P | Communications Biology | 2021 | | |
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo |
| Thom T, Schmitz M, (...), Zerr I | Movement Disorders | 2021 | | |
Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons |
| Sertel SM, Blumenstein W, Mandad S, Shomroni O, Salinas G, Rizzoli SO | Scientific Reports | 2021 | | |
Structural basis of RNA processing by human mitochondrial RNase P |
| Bhatta A, Dienemann C, Cramer P, Hillen HS | Nature Structural & Molecular Biology | 2021 | | |
Fibroblast Derived Human Engineered Connective Tissue for Screening Applications | | Santos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz S | Journal of Visualized Experiments | 2021 | | |
Structure of an inactive RNA polymerase II dimer |
| Aibara S, Dienemann C, Cramer P | Nucleic Acids Research | 2021 | | |
Structural basis of human transcription–DNA repair coupling |
| Kokic G, Wagner FR, Chernev A, Urlaub H, Cramer P | Nature | 2021 | | |
Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy |
| Yigit G, Wollnik B | Medizinische Genetik | 2021 | | |
H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion |
| Kerimoglu C, Pham L, (...), Tuoc T | Science Advances | 2021 | | |
RNF43 Pathogenic Germline Variant in a Family with Colorectal Cancer | | Mikaeel RR, Young JP, (...), Price TJ | Clinical Genetics | 2021 | | |
Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration |
| Liu JK, Gollisch T | bioRxiv | 2021 | | |
Management of Metadata Types in Basic Cardiological Research |
| Kusch H, Kossen R, (...), Nussbeck SY | Studies in Health Technology and Informatics | 2021 | | |
The bumpy road of FAIRification in practice |
| Kusch H, Bauer CR, (...), Sax U | German Medical Science GMS Publishing House | 2021 | | |
The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1 |
| Sadredini M, Manotheepan R, Lehnart SE, Anderson ME, Sjaastad I, Stokke MK | Physiological reports | 2021 | | |
Biallelic variants in YRDC cause a developmental disorder with progeroid features |
| Schmidt J, Goergens J, (...), Wollnik B | Human Genetics | 2021 | | |
Mapping protein interactions in the active TOM-TIM23 supercomplex |
| Gomkale R, Linden A, (...), Rehling P | Nature Communications | 2021 | | |
GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072 |
| Kusch H, Bauer CR, (...), Sax U | Göttingen Research Online / Data | 2021 | | |
Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501 |
| Goldberg M, Islam MR, (...), Fischer A | Translational Psychiatry | 2021 | | |
Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis |
| Lavdovskaia E, Hillen HS, Richter-Dennerlein R | Trends in Cell Biology | 2021 | | |
Familial cleft tongue caused by a unique translation initiation codon variant in TP63 |
| Schmidt J, Schreiber G, (...), Wollnik B | European Journal of Human Genetics | 2021 | | |
Intracellular softening and increased viscoelastic fluidity during division |
| Hurst S, Vos BE, Brandt M, Betz T | Nature Physics | 2021 | | |
Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy |
| Khan A, Ramos-Gomes F, Markus A, Mietsch M, Hinkel R, Alves F | Biomedical Optics Express | 2021 | | |
An in vitro system to silence mitochondrial gene expression |
| Cruz-Zaragoza LD, Dennerlein S, (...), Rehling P | Cell | 2021 | | |
A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease |
| Shomroni O, Sitte M, (...), Salinas G | Researchsquare | 2021 | | |
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy |
| Bertero E, Nickel A, (...), Maack C | Circulation | 2021 | | |
Instant three-color multiplane fluorescence microscopy |
| Gregor I, Butkevich E, Enderlein J, Mojiri S | Biophysical Reports | 2021 | | |
Structural basis of Integrator-mediated transcription regulation | | Fianu I, Chen Y, (...), Cramer P | Science | 2021 | | |
Effects of cryo-EM cooling on structural ensembles |
| Bock LV, Grubmüller H | bioRxiv | 2021 | | |
Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy |
| Kettwig M, Ternka K, (...), Gärtner J | Nature Communications | 2021 | | |
Exfoliation and Optical Properties of Near-Infrared Fluorescent Silicate Nanosheets |
| Selvaggio G, Weitzel M, (...), Kruss S | ChemRxiv | 2021 | | |
Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography |
| Eckermann M, van der Meer F, (...), Salditt T | Biomedical Optics Express | 2021 | | |
Alpha-Synuclein Antibody Characterization: Why Semantics Matters |
| Outeiro TF | Molecular Neurobiology | 2021 | | |
Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations | | Fomin A, Gärtner A, (...), Linke WA | Science Translational Medicine | 2021 | | |
Understanding and treating paediatric hearing impairment |
| Wrobel C, Zafeiriou M, Moser T | EBioMedicine | 2021 | | |
Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival | | Zelarayan L, Vendrell V, (...), Schimmang T | Developmental Dynamics | 2021 | | |
Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast Interactions | | Zimmermann W | Circulation Research | 2021 | | |
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels |
| Eisenberg-Bord M, Zung N, (...), Schuldiner M | Journal of Cell Biology | 2021 | | |
The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels |
| Brüser C, Keller-Findeisen J, Jakobs S | Cell Reports | 2021 | | |
Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes |
| Michurina A, Sakib MS, (...), Fischer A | EMBO Journal | 2021 | | |
Free-Breathing Myocardial T1 Mapping using Inversion-Recovery Radial FLASH and Motion-Resolved Model-Based Reconstruction |
| Wang X, Rosenzweig S, (...), Uecker M | arXiv | 2021 | | |
Mechanism of SARS-CoV-2 polymerase stalling by remdesivir |
| Kokic G, Hillen HS, (...), Cramer P | Nature Communications | 2021 | | |
Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography |
| Eckermann M, Schmitzer B, (...), Salditt T | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
Aneuploidy in human eggs: contributions of the meiotic spindle |
| Thomas C, Cavazza T, Schuh M | Biochemical Society Transactions | 2021 | | |
Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2 Interaction in Constrained Geometries | | Dietz J, Oelkers M, (...), Janshoff A | Nano Letters | 2021 | | |
Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States |
| Neher E, Taschenberger H | Neuroscience | 2021 | | |
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
| Dankovich TM, Kaushik R, (...), Rizzoli SO | Nature Communications | 2021 | | |
Towards correlative imaging of neuronal tissue by phase-contrast x-ray tomography and SEM |
| Eckermann M, Ruhwedel T, Möbius W, Salditt T | Developments in X-Ray Tomography XIII | 2021 | | |
Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy |
| Perego E, Köster S | Lab on a Chip | 2021 | | |
Minimax detection of localized signals in statistical inverse problems |
| Pohlmann M, Werner F, Munk A | arXiv | 2021 | | |
Trans-synaptic assemblies link synaptic vesicles and neuroreceptors |
| Martinez-Sanchez A, Laugks U, (...), Lučić V | Science Advances | 2021 | | |
Epigenetic gene expression links heart failure to memory impairment |
| Islam MR, Lbik D, (...), Fischer A | EMBO Molecular Medicine | 2021 | | |
Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms |
| Heinemann F, Klatt M, Munk A | arXiv | 2021 | | |
Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis |
| Hofemeier AD, Limón T, (...), Betz T | Elife | 2021 | | |
Electronic laboratory notekeeping at the Göttingen Campus |
| Kusch H | Zenodo | 2021 | | |
Phase Separation during Germline Development |
| So C, Cheng S, Schuh M | Trends in Cell Biology | 2021 | | |
Super-resolution imaging: when biophysics meets nanophotonics |
| Koenderink AF, Tsukanov R, Enderlein J, Izeddin I, Krachmalnicoff V | Nanophotonics | 2021 | | |
Regulation of a subset of release-ready vesicles by the presynaptic protein Mover |
| Pofantis E, Neher E, Dresbach T | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells |
| Vasili E, Dominguez-Meijide A, (...), Outeiro T | Researchsquare | 2021 | | |
NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover |
| Bonnin EA, Fornasiero EF, Lange F, Turck CW, Rizzoli SO | BMC Molecular and Cell Biology | 2021 | | |
Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors |
| Nadler F, Lavdovskaia E, Richter-Dennerlein R | RNA Biology | 2021 | | |
Free-Breathing Water, Fat, R⋆2 and B0 Field Mapping of the Liver Using Multi-Echo Radial FLASH and Regularized Model-based Reconstruction (MERLOT) |
| Tan Z, Rosenzweig S, (...), Uecker M | arXiv | 2021 | | |
Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer |
| Thiele JC, Jungblut M, (...), Enderlein J | bioRxiv | 2021 | | |
Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness |
| Rankovic V, Vogl C, (...), Moser T | Frontiers in Molecular Neuroscience | 2021 | | |
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity |
| Riera-Tur I, Schäfer T, (...), Dudanova I | Life Science Alliance | 2021 | | |
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea |
| Hua Y, Ding X, (...), Wu H | Cell Reports | 2021 | | |
Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging | | Raja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh A | Nano Letters | 2021 | | |
Role of GTPases in Driving Mitoribosome Assembly | | Maiti P, Lavdovskaia E, Barrientos A, Richter-Dennerlein R | Trends in Cell Biology | 2021 | | |
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis |
| Kabinger F, Stiller C, (...), Cramer P | Nature Structural & Molecular Biology | 2021 | | |
RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse |
| Butola T, Alvanos T, (...), Moser T | Journal of Neuroscience | 2021 | | |
Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors |
| Dennerlein S, Poerschke S, (...), Rehling P | eLife | 2021 | | |
Molecular and functional architecture of striatal dopamine release sites | | Banerjee A, Imig C, (...), Kaeser PS | Neuron | 2021 | | |
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study |
| Tampe D, Hakroush S, (...), Tampe B | Frontiers in Medicine | 2021 | | |
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion |
| Grabner CP, Moser T | eLife | 2021 | | |
Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis |
| Barbarics B, Eildermann K, (...), Bohnenberger H | Scientific Reports | 2021 | | |
3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography |
| Reichardt M, Moller Jensen P, (...), Salditt T | eLife | 2021 | | |
Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms | | Moebel E, Martinez-Sanchez A, (...), Kervrann C | Nature Methods | 2021 | | |
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery |
| Walter C, Marada A, (...), Meisinger C | Nature Communications | 2021 | | |
Towards Visual Proteomics at High Resolution |
| Bäuerlein FJ, Baumeister W | Journal of Molecular Biology | 2021 | | |
Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission |
| Lipstein N, Chang S, (...), Brose N | Neuron | 2021 | | |
Allosteric control of Ubp6 and the proteasome via a bidirectional switch |
| Hung KYS, Klumpe S, (...), Finley D | bioRxiv | 2021 | | |
Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo | | Žumer K, Maier KC, (...), Cramer P | Molecular Cell | 2021 | | |
Structures and implications of TBP–nucleosome complexes |
| Wang H, Xiong L, Cramer P | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
Optimal transfer functions for bandwidth-limited imaging |
| Stallinga S, Delon A, Enderlein J | arXiv | 2021 | | |
Advanced Data Analysis for Fluorescence-Lifetime Single-Molecule Localization Microscopy |
| Thiele JC, Nevskyi O, Helmerich DA, Sauer M, Enderlein J | Frontiers in Bioinformatics | 2021 | | |
Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator |
| Perera RP, Shaikhqasem A, (...), Dosch R | Biomolecules | 2021 | | |
Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner |
| Sokpor G, Kerimoglu C, (...), Tuoc T | Frontiers in Molecular Neuroscience | 2021 | | |
Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain |
| Abbas E, Hassan MA, (...), Tuoc T | Frontiers in Cell and Developmental Biology | 2021 | | |
Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus |
| Akol I, Heidrich S, (...), Vogel T | bioRxiv | 2021 | | |
A microRNA signature that correlates with cognition and is a target against cognitive decline |
| Islam MR, Kaurani L, (...), Fischer A | EMBO Molecular Medicine | 2021 | | |
Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity |
| Shahriyari M, Islam MR, (...), Tiburcy M | bioRxiv | 2021 | | |
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders |
| Klemp HG, Kettwig M, Streit F, Gärtner J, Rosewich H, Krätzner R | Metabolites | 2021 | | |
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics |
| Beckert B, Leroy EC, (...), Wilson DN | Nature Communications | 2021 | | |
A mathematical model for electrical activity in pig atrial tissue |
| Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R | bioRxiv | 2021 | | |
Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model |
| Oestreicher D, Picher MM, Rankovic V, Moser T, Pangrsic T | Frontiers in Molecular Neuroscience | 2021 | | |
Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation |
| Popova B, Wang D, (...), Braus GH | Frontiers in Molecular Neuroscience | 2021 | | |
Small Molecule Fisetin Modulates Alpha–Synuclein Aggregation |
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Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease |
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Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation |
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Ectosomes and exosomes are distinct proteomic entities that modulate spontaneous activity in neuronal cells |
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Molecular bases of mitochondrial disorders |
| Chacinska A, Rehling P | FEBS Letters | 2021 | | |
Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies |
| Cappello S, Sung H, (...), Bogeski I | Cancer Research | 2021 | | |
Impaired Exercise Tolerance in Repaired Tetralogy of Fallot Is Associated With Impaired Biventricular Contractile Reserve: An Exercise-Stress Real-Time Cardiovascular Magnetic Resonance Study |
| Steinmetz M, Stümpfig T, (...), Paul T | Circulation-Cardiovascular Imaging | 2021 | | |
0753 Free-Breathing Liver Fat and R2* Mapping: Multi-Echo Radial FLASH and Model-based Reconstruction (MERLOT) |
| Tan Z, Rosenzweig S, (...), Uecker M | Proceedings of the 2021 ISMRM & SMRT Annual Meeting & Exhibition | 2021 | | |
Genomic basis of syndromic short stature in an Algerian patient cohort | | Moosa S, Chentli F, (...), Wollnik B | American Journal of Medical Genetics Part A | 2021 | | |
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures |
| Gönenc II, Wolff A, (...), Wollnik B | bioRxiv | 2021 | | |
Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering |
| Raad FS, Khan TA, (...), Zimmermann W | ChemMedChem | 2021 | | |
Cell programming to protect the ischemic heart and limb |
| Brittan M, Zimmermann W | Molecular Therapy | 2021 | | |
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation |
| Schoger E, Zimmermann W, Cyganek L, Zelarayán LC | Stem Cell Research | 2021 | | |
Author Correction: Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms |
| Moebel E, Martinez-Sanchez A, (...), Kervrann C | Nature Methods | 2021 | | |
Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review |
| Müllenbroich MC, Kelly A, (...), Smith GL | Frontiers in Physiology | 2021 | | |
The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool |
| Wegener JW, Wagdi A, (...), Lehnart SE | Frontiers in Physiology | 2021 | | |
Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer | | Mikaeel RR, Young JP, (...), Price TJ | Genes Chromosomes and Cancer | 2021 | | |
Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
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Challenges facing quantitative large-scale optical super-resolution, and some simple solutions |
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Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue |
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Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer |
| Füllbrunn N, Li Z, (...), You C | Elife | 2021 | | |
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders |
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Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes |
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Transcriptionally active enhancers in human cancer cells |
| Lidschreiber K, Jung LA, (...), Lidschreiber M | Molecular Systems Biology | 2021 | | |
Combined scanning small-angle X-ray scattering and holography probes multiple length scales in cell nuclei |
| Wittmeier A, Cassini C, (...), Köster S | Journal of Synchrotron Radiation | 2021 | | |
Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy |
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Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast |
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Stress-induced nuclear condensation of NELF drives transcriptional downregulation |
| Rawat P, Boehning M, (...), Sawarkar R | Molecular Cell | 2021 | | |
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells |
| Tegunov D, Xue L, Dienemann C, Cramer P, Mahamid J | Nature Methods | 2021 | | |
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
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Monitoring mitochondrial translation in living cells |
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Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers |
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Emerging concepts in synucleinopathies |
| Outeiro TF | Acta Neuropathologica | 2021 | | |
New Species Can Broaden Myelin Research: Suitability of Little Skate, Leucoraja erinacea |
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The Coding and Small Non-coding Hippocampal Synaptic RNAome |
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Transcription activation depends on the length of the RNA polymerase II C‐terminal domain |
| Sawicka A, Villamil G, (...), Cramer P | EMBO Journal | 2021 | | |
Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling |
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Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
| Koss DJ, Erskine D, (...), Outeiro TF | bioRxiv | 2021 | | |
PolyQ expansion does not alter the Huntingtin-HAP40 complex |
| Huang B, Guo Q, (...), Fernández-Busnadiego R | bioRxiv | 2021 | | |
Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels |
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Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies |
| Brás IC, Outeiro TF | Cells | 2021 | | |
Two mechanisms drive pronuclear migration in mouse zygotes |
| Scheffler K, Uraji J, (...), Schuh M | Nature Communications | 2021 | | |
Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy |
| Oliveira da Silva MI, Santejo M, (...), Liz M | bioRxiv | 2021 | | |
RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses |
| Krinner S, Predoehl F, Burfeind D, Vogl C, Moser T | Frontiers in Molecular Neuroscience | 2021 | | |
The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term |
| Reshetniak S, Rizzoli SO | Current Opinion in Cell Biology | 2021 | | |
Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control | | Hoffmann S, Schmitteckert S, (...), Rappold G | Biochimica et Biophysica Acta-Gene Regulatory Mechanisms | 2021 | | |
Efficient RNA polymerase II pause release requires U2 snRNP function | | Caizzi L, Monteiro-Martins S, (...), Cramer P | Molecular Cell | 2021 | | |
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling |
| Hillen HS, Lavdovskaia E, (...), Richter-Dennerlein R | bioRxiv | 2021 | | |
Colocalization for super-resolution microscopy via optimal transport |
| Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk A | Nature Computational Science | 2021 | | |
Origins and mechanisms leading to aneuploidy in human eggs |
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Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
| Yudovich S, Marzouqe A, (...), Weiss S | bioRxiv | 2021 | | |
Presynaptic activity and protein turnover are correlated at the single-synapse level |
| Jähne S, Mikulasch F, (...), Priesemann V | Cell Reports | 2021 | | |
Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications |
| Vanegas LJ, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk A | arXiv | 2021 | | |
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex |
| Ulmke PA, Sakib MS, (...), Tuoc T | Stem Cell Reports | 2021 | | |
Structure and function of SARS-CoV-2 polymerase |
| Hillen HS | Current Opinion in Virology | 2021 | | |
The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs |
| Hillen HS, Markov DA, (...), Anikin M | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
The structure of Prp2 bound to RNA and ADP-BeF3− reveals structural features important for RNA unwinding by DEAH-box ATPases |
| Hamann F, Zimmerningkat LC, (...), Ficner R | Acta Crystallographica Section D-Structural Biology | 2021 | | |
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding |
| Bartsch A, Ives CM, (...), Llabrés S | Biochimica et Biophysica Acta-Biomembranes | 2021 | | |
Multiscale photonic imaging of the native and implanted cochlea |
| Keppeler D, Kampshoff CA, (...), Moser T | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
The Cdk8 kinase module regulates interaction of the Mediator complex with RNA polymerase II |
| Osman S, Mohammad E, (...), Cramer P | Journal of Biological Chemistry | 2021 | | |
Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo |
| Albert K, Raymundo DP, (...), Airavaara M | Molecular Therapy | 2021 | | |
Parental genome unification is highly error-prone in mammalian embryos |
| Cavazza T, Takeda Y, (...), Schuh M | Cell | 2021 | | |
Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway |
| Bali B, Lopez de la Morena D, (...), Moser T | EMBO Molecular Medicine | 2021 | | |
Tissue engineered heart repair from preclinical models to first-in-patient studies | | Zimmermann W | Current Opinion in Physiology | 2020 | | |
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea |
| Hua Y, Ding X, (...), Wu H | bioRxiv | 2020 | | |
Epigenetic gene-expression links heart failure to memory impairment |
| Islam R, Lbik D, (...), Fischer A | bioRxiv | 2020 | | |
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology | | Kargapolova Y, Rehimi R, (...), Papantonis A | bioRxiv | 2020 | | |
Pixel hopping enables fast STED nanoscopy at low light dose |
| Vinçon B, Geisler C, Egner A | Optics Express | 2020 | | |
Light Microscopy of Mitochondria at the Nanoscale | | Jakobs S, Stephan T, Ilgen P, Brüser C | Annual Review of Biophysics | 2020 | | |
Nanoscale x-ray holotomography of human brain tissue with phase retrieval based on multienergy recordings |
| Robisch A, Eckermann M, Töpperwien M, van der Meer F, Stadelmann-Nessler C, Salditt T | Journal of Medical Imaging | 2020 | | |
Phase-contrast x-ray tomography of neuronal tissue at laboratory sources with submicron resolution |
| Eckermann M, Töpperwien M, Robisch A, van der Meer F, Stadelmann C, Salditt T | Journal of Medical Imaging | 2020 | | |
Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease |
| Töpperwien M, van der Meer F, Stadelmann C, Salditt T | Neuroimage | 2020 | | |
Multiscale Quantile Segmentation | | Vanegas LJ, Behr M, Munk A | Journal of the American Statistical Association | 2020 | | |
Structure of the transcription coactivator SAGA | | Wang H, Dienemann C, Stützer A, Urlaub H, Cheung ACM, Cramer P | Nature | 2020 | | |
Molecular signature of slowly expanding lesions in progressive multiple sclerosis |
| Jäckle K, Zeis T, (...), Brück W | Brain | 2020 | | |
Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative Nanoscopy | | Staudt T, Aspelmeier T, Laitenberger O, Geisler C, Egner A, Munk A | Statistical Science | 2020 | | |
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles |
| Grabner CP, Moser T | bioRxiv | 2020 | | |
Stress- and ubiquitylation-dependent phase separation of the proteasome | | Yasuda S, Tsuchiya H, (...), Saeki Y | Nature | 2020 | | |
Molecular and functional architecture of striatal dopamine release sites |
| Banerjee A, Imig C, (...), Kaeser PS | bioRxiv | 2020 | | |
Choice of fluorophore affects dynamic DNA nanostructures |
| Jahnke K, Grubmüller H, Igaev M, Göpfrich K | bioRxiv | 2020 | | |
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
| Oberbeckmann E, Niebauer V, (...), Korber P | bioRxiv | 2020 | | |
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses |
| Maus L, Lee C, (...), Cooper BH | Cell Reports | 2020 | | |
Emerging approaches for restoration of hearing and vision |
| Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser T | Physiological Reviews | 2020 | | |
Kinetics of Loop Closure in Disordered Proteins: Theory vs Simulations vs Experiments | | Satija R, Das A, Mühle S, Enderlein J, Makarov DE | Journal of Physical Chemistry B | 2020 | | |
Wide-Field Fluorescence Lifetime Imaging of Single Molecules | | Oleksiievets N, Thiele JC, (...), Enderlein J | Journal of Physical Chemistry A | 2020 | | |
A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19 |
| Islam MR, Fischer A | preprints.org | 2020 | | |
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function | | Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P | Nature | 2020 | | |
Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
| Zheng X, Zhang L, (...), Doeppner TR | Translational Stroke Research | 2020 | | |
What is resolution? A statistical minimax testing perspective on super-resolution microscopy |
| Kulaitis G, Munk A, Werner F | arXiv | 2020 | | |
Structure of replicating SARS-CoV-2 polymerase |
| Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov D, Cramer P | Nature | 2020 | | |
Elemental quantification and analysis of structural abnormalities in neurons from Parkinson’s-diseased brains by X-ray fluorescence microscopy and diffraction |
| Joppe K, Nicolas J, Grünewald TA, Eckermann M, Salditt T, Lingor P | Biomedical Optics Express | 2020 | | |
A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome |
| Drivas TG, Li D, (...), Bhoj E | European Journal of Human Genetics | 2020 | | |
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response | | Stik G, Vidal E, (...), Graf T | Nature Genetics | 2020 | | |
Large field-of-view scanning small-angle X-ray scattering of mammalian cells |
| Cassini C, Wittmeier A, Brehm G, Denz M, Burghammer M, Köster S | Journal of Synchrotron Radiation | 2020 | | |
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation | | Vos SM, Farnung L, Linden A, Urlaub H, Cramer P | Nature Structural & Molecular Biology | 2020 | | |
Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis |
| Backhaus SJ, Lange T, (...), Schuster A | Journal of Cardiovascular Magnetic Resonance | 2020 | | |
MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation |
| Stephan T, Brüser C, (...), Jakobs S | EMBO Journal | 2020 | | |
μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve |
| Dieter A, Klein E, (...), Moser T | EMBO Molecular Medicine | 2020 | | |
The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27 |
| Lemus-Diaz N, Ferreira RR, Bohnsack KE, Gruber J, Bohnsack MT | Nucleic Acids Research | 2020 | | |
A comparative analysis of the mobility of 45 proteins in the synaptic bouton |
| Reshetniak S, Ußling J, (...), Rizzoli SO | EMBO Journal | 2020 | | |
The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
| Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B | preprints.org | 2020 | | |
Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture | | Chizhik AI, Chizhik AM, (...), Enderlein J | Methods in Molecular Biology | 2020 | | |
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents | | Keppeler D, Schwaerzle M, (...), Moser T | Science Translational Medicine | 2020 | | |
Remyelination in multiple sclerosis: from basic science to clinical translation | | Lubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff B | Lancet Neurology | 2020 | | |
Reliable estimation of membrane curvature for cryo-electron tomography |
| Salfer M, Collado JF, Baumeister W, Fernández-Busnadiego R, Martínez-Sánchez A | PLOS Computational Biology | 2020 | | |
CG-SENSE revisited: Results from the first ISMRM reproducibility challenge |
| Maier O, Baete SH, (...), Knoll F | arXiv | 2020 | | |
Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins |
| Pape JK, Stephan T, (...), Hell SW | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
The mRNA-Binding Protein RBM3 Regulates Activity Patterns and Local Synaptic Translation in Cultured Hippocampal Neurons |
| Sertel SM, von Elling-Tammen MS, Rizzoli SO | Journal of Neuroscience | 2020 | | |
Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control |
| Hu Y, Korovaichuk A, (...), Bringmann H | Genetics | 2020 | | |
Heterogeneous Idealization of Ion Channel Recordings - Open Channel Noise |
| Pein F, Bartsch A, Steinem C, Munk A | arXiv | 2020 | | |
Dopamine promotes the neurodegenerative potential of β‐synuclein |
| Raina A, Leite K, (...), Kügler S | Journal of Neurochemistry | 2020 | | |
Rosalind Franklin and the Advent of Molecular Biology |
| Cramer P | Cell | 2020 | | |
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids |
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Structural Biology of RNA Polymerase II Transcription: 20 Years On | | Osman S, Cramer P | Annual Review of Cell and Developmental Biology | 2020 | | |
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban | | Menzel J, Kownatzki-Danger D, (...), Schwappach B | Science Signaling | 2020 | | |
Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex |
| Heimes M, Fiorentino F, (...), Sinning I | Molecular Cell | 2020 | | |
3D analysis of the myenteric plexus of the human bowel by X-ray phase-contrast tomography – a future method? |
| Peruzzi N, Veress B, (...), Ohlsson B | Scandinavian Journal of Gastroenterology | 2020 | | |
Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells |
| Bäuerlein FJ, Fernández-Busnadiego R, Baumeister W | Trends in Cell Biology | 2020 | | |
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices |
| Imig C, López-Murcia FJ, (...), Cooper BH | Neuron | 2020 | | |
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity |
| Cantuti-Castelvetri L, Ojha R, (...), Simons M | Science | 2020 | | |
MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis |
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Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries |
| Kovacs S, Li H, Haubner L, Munk A, Bühlmann P | arXiv | 2020 | | |
Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software |
| Pein F, Eltzner B, Munk A | CRAN | 2020 | | |
Quantitative analysis of hidden particles diffusing behind a scattering layer using speckle correlation |
| Sarkar A, Wang I, Enderlein J, Derouard J, Delon A | Optics Express | 2020 | | |
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide | | Montiel V, Bella R, (...), Balligand J | Science Translational Medicine | 2020 | | |
Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy |
| Thiele JC, Helmerich DA, (...), Enderlein J | ACS Nano | 2020 | | |
Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia |
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Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson’s disease patients |
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3d phase‐contrast nanotomography of unstained human skin biopsies may identify morphological differences in the dermis and epidermis between subjects |
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Physics-based Reconstruction Methods for Magnetic Resonance Imaging |
| Wang X, Tan Z, Scholand N, Roeloffs V, Uecker M | arXiv | 2020 | | |
Variational multiscale nonparametric regression: Algorithms |
| del Alamo M, Li H, Munk A, Werner F | arXiv | 2020 | | |
3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography |
| Frohn J, Pinkert-Leetsch D, (...), Salditt T | Journal of Synchrotron Radiation | 2020 | | |
Defining the architecture of the human TIM22 complex by chemical crosslinking |
| Valpadashi A, Callegari S, (...), Rehling P | FEBS Letters | 2020 | | |
Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity |
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Engineered Heart Muscle Models in Phenotypic Drug Screens | | Zimmermann W | Handb Exp Pharmacol | 2020 | | |
Pharmacological Modulators of Tau Aggregation and Spreading |
| Dominguez-Meijide A, Vasili E, Outeiro TF | Brain Sciences | 2020 | | |
Variational Multiscale Nonparametric Regression: Algorithms and Implementation |
| del Alamo M, Li H, Munk A, Werner F | Algorithms | 2020 | | |
Viral rhodopsins 1 are an unique family of light-gated cation channels |
| Zabelskii D, Alekseev A, (...), Gordeliy V | Nature Communications | 2020 | | |
From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease |
| Outeiro TF, Heutink P, Bezard E, Cenci AM | Movement Disorders | 2020 | | |
Efficient modeling of three-dimensional convection–diffusion problems in stationary flows |
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Ion type and valency differentially drive vimentin tetramers into intermediate filaments or higher order assemblies |
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Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy |
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Doubling the resolution of a confocal spinning-disk microscope using image scanning microscopy | | Qin S, Isbaner S, Gregor I, Enderlein J | Nature Protocols | 2020 | | |
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 |
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A minimalist model to measure interactions between proteins and synaptic vesicles |
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The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin |
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Alpha‐synuclein oligomerization and aggregation: a model will always be a model |
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[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates |
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X-ray diffraction and second harmonic imaging reveal new insights into structural alterations caused by pressure-overload in murine hearts |
| Nicolas J, Khan A, (...), Salditt T | Scientific Reports | 2020 | | |
A sensory cell diversifies its output by varying Ca2+ influx‐release coupling among active zones |
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Cancer and Parkinson's Disease: Common Targets, Emerging Hopes | | Filippou PS, Outeiro TF | Movement Disorders | 2020 | | |
Small-molecule inhibitors of human mitochondrial DNA transcription |
| Bonekamp NA, Peter B, (...), Larsson N | Nature | 2020 | | |
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples | | Parfentev I, Schilbach S, Cramer P, Urlaub H | Journal of Proteomics | 2020 | | |
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol |
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Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination |
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Integrator is a genome-wide attenuator of non-productive transcription | | Lykke-Andersen S, Žumer K, (...), Jensen TH | Molecular Cell | 2020 | | |
Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
| Jean P, Anttonen T, (...), Moser T | Nature Communications | 2020 | | |
Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes | | Seibertz F, Reynolds M, Voigt N | Journal of Visualized Experiments | 2020 | | |
Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells |
| Effertz T, Moser T, Oliver D | Faculty Reviews | 2020 | | |
Molecular and cellular dynamics of the 26S proteasome |
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Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐based Exchangeable Fluorophores |
| Glogger M, Spahn C, Enderlein J, Heilemann M | Angewandte Chemie-International Edition | 2020 | | |
Post-translational modifications soften vimentin intermediate filaments |
| Kraxner J, Lorenz C, (...), Köster S | Nanoscale | 2020 | | |
Aplasia cutis congenita in a CDC42‐related developmental phenotype | | Schnabel F, Kamphausen SB, Funke R, Kaulfuß S, Wollnik B, Zenker M | American Journal of Medical Genetics Part A | 2020 | | |
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes |
| Lavdovskaia E, Denks K, (...), Richter-Dennerlein R | Nucleic Acids Research | 2020 | | |
Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees |
| Heinemann F, Munk A, Zemel Y | arXiv | 2020 | | |
Structural basis of nucleosome transcription mediated by Chd1 and FACT |
| Farnung L, Ochmann M, Engeholm M, Cramer P | bioRxiv | 2020 | | |
Cellular and mitochondrial mechanisms of atrial fibrillation |
| Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N | Basic Research in Cardiology | 2020 | | |
The Coding And Small-Non-Coding Hippocampal Synaptic RNAome |
| Epple R, Krüger D, (...), Fischer A | bioRxiv | 2020 | | |
Drosophila Mechanosensory Transduction | | Hehlert P, Zhang W, Göpfert MC | Trends in Neurosciences | 2020 | | |
Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity |
| Medina L, González-Lizárraga F, (...), Socias SB | bioRxiv | 2020 | | |
CG‐SENSE revisited: Results from the first ISMRM reproducibility challenge |
| Maier O, Baete SH, (...), Knoll F | Magnetic Resonance in Medicine | 2020 | | |
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
| Dankovich TM, Kaushik R, (...), Rizzoli SO | bioRxiv | 2020 | | |
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2 |
| Kreutzberger AJ, Kiessling V, (...), Tamm LK | eLife | 2020 | | |
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
| Dominguez-Meijide A, Parrales V, (...), Outeiro TF | bioRxiv | 2020 | | |
Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes |
| Dijkman PM, Muñoz-García JC, (...), Watts A | Science Advances | 2020 | | |
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding |
| Bartsch A, Ives C, (...), Llabrés S | bioRxiv | 2020 | |