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Empirical Optimal Transport under Estimated Costs: Distributional Limits and Statistical Applications |
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Translation Factor Accelerating Peptide Bond Formation on the Ribosome: EF-P and eIF5A as Entropic Catalysts and a Potential Drug Targets |
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Impact of the Euro 2020 championship on the spread of COVID-19 |
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Trafficking proteins show limited differences in mobility across different postsynaptic spines |
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Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling |
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Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes |
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Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy |
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Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users |
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Graded optogenetic activation of the auditory pathway for hearing restoration |
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LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome |
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Natural stimuli drive concerted nonlinear responses in populations of retinal ganglion cells |
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Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes |
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Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome |
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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system |
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Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF |
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Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency |
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Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reaction | | Fu Y, Simeth NA, Toyoda R, Brilmayer R, Szymanski W, Feringa BL | Angewandte Chemie-International Edition | 2023 | | |
Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism |
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Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis |
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Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts |
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The multifaceted mitochondrial OXA insertase |
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Defective COX1 expression in aging mice liver |
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In vitro reconstitution of chromatin domains |
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Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation |
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The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies |
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Excitation Intensity-Dependent Quantum Yield of Semiconductor Nanocrystals |
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Impact of Phosphorylation on alpha-Synuclein Structural Determinants |
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A quantitative fluorescence‐based approach to study mitochondrial protein import |
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Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel | | Pan Y, Pohjolainen E, (...), Scheuring S | Nature Structural & Molecular Biology | 2023 | | |
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain |
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Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes |
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Towards a Biological Definition of Parkinson’s Disease |
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Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR |
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Reverse-time analysis uncovers universality classes in directional biological dynamics |
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Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise |
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Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons |
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C1q is increased in cerebrospinal fluid‐derived extracellular vesicles in Alzheimer's disease: A multi‐cohort proteomics and immuno‐assay validation study |
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Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination |
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Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation |
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A novel miR-99b-5p-<i>Zbp1</i>pathway in microglia contributes to the pathogenesis of schizophrenia |
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Bayesian MRI reconstruction with joint uncertainty estimation using diffusion models |
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A small-angle X-ray scattering study of red blood cells in continuous flow |
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IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart |
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3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis |
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The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments |
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A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag |
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Influence of phosphorylation on intermediate filaments | | Kraxner J, Köster S | Biological Chemistry | 2023 | | |
Signatures of heterogeneity in the statistical structure of target state aligned ensembles |
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Adaptive minimax optimality in statistical inverse problems via SOLIT -- Sharp Optimal Lepskii-Inspired Tuning |
| Li H, Werner F | arXiv | 2023 | | |
Quantitative MRI by nonlinear inversion of the Bloch equations |
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Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V |
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Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V |
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The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued |
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Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis |
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A metabolically controlled contact site between lipid droplets and vacuoles |
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Vimentin intermediate filaments structure and mechanically support microtubules in cells |
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Protein transport along the presequence pathway | | Makki A, Rehling P | Biological Chemistry | 2023 | | |
Structural basis of catalytic activation in human splicing |
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Decoding and Recoding of mRNA Sequences by the Ribosome |
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Human lung virtual histology by multi-scale x-ray phase-contrast computed tomography |
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Fluorescence Spectroscopy in Planar Dielectric and Metallic Systems | | Chizhik AI, Ruhlandt D, Enderlein J | Photonic Quantum Technologies | 2023 | | |
In vitro and in vivo characterization of improved channelrhodopsin ChRmine variants for optogenetic activation of the auditory pathway | | Zerche M, Hunniford V, Witzke I, Wolf B, Mager T, Moser T | Laryngo-Rhino-Otologie | 2023 | | |
Characterization of novel channelrhodopsin variants for blue-light optogenetic activation of the auditory pathway | | Roos L, Garrido-Charles A, Wolf B, Kusch K, Mager T, Moser T | Laryngo-Rhino-Otologie | 2023 | | |
Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative Analysis | | Oleksiievets N, Mathew C, (...), Enderlein J | Nano Letters | 2022 | | |
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial |
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Remote control of the heart and beyond | | Zimmermann W | Science | 2022 | | |
A Mathematical Model for Electrical Activity in Pig Atrial Tissue |
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Allosteric control of Ubp6 and the proteasome via a bidirectional switch |
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WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly | | Bögershausen N, Krawczyk HE, (...), Wollnik B | Human Mutation | 2022 | | |
Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration |
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Statistical spatial analysis for cryo-electron tomography |
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Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control |
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Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants |
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Is there an unmet medical need for improved hearing restoration? | | Wolf BJ, Kusch K, (...), Moser T | EMBO Molecular Medicine | 2022 | | |
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function |
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Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX |
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Structure of a backtracked hexasomal intermediate of nucleosome transcription | | Farnung L, Ochmann M, Garg G, Vos SM, Cramer P | Molecular Cell | 2022 | | |
Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology |
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HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation |
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Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43 |
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Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory |
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A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data |
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Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice |
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α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals |
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The 3D structure of lipidic fibrils of α-synuclein |
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Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes |
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Production of Recombinant Alpha-Synuclein: Still No Standardized Protocol in Sight |
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Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues | | Santos GL, DeGrave AN, (...), Lutz S | Biomaterials Advances | 2022 | | |
Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3 |
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A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming |
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JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species | | Santos CC, Cardim-Pires TR, (...), Silva VDA | Neurotoxicity Research | 2022 | | |
Multiscale architecture: Mechanics of composite cytoskeletal networks |
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Combined optical fluorescence microscopy andX-ray tomography reveals substructures in cellnuclei in 3D |
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DNA-PAINT MINFLUX nanoscopy |
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IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter |
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Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis |
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Interdomain Dynamics via Paramagnetic NMR on the Highly Flexible Complex Calmodulin/Munc13-1 |
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The murine male reproductive organ at a glance: Three‐dimensional insights and virtual histology using label‐free light sheet microcopy |
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Ectosomes and exosomes modulate neuronal spontaneous activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Proteomics | 2022 | | |
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes |
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Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II |
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Quantitative Magnetic Resonance Imaging by Nonlinear Inversion of the Bloch Equations |
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A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry |
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A Sequential Two-Step Priming Scheme Reproduces Diversity in Synaptic Strength and Short-Term Plasticity |
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A Variational View on Statistical Multiscale Estimation | | Haltmeier M, Li H, Munk A | Annual Review of Statistics and Its Application | 2022 | | |
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
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Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts |
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Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients |
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Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice |
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Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden |
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MRI Reconstruction via Data Driven Markov Chain with Joint Uncertainty Estimation |
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Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain |
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Retinal Encoding of Natural Scenes | | Karamanlis D, Schreyer HM, Gollisch T | Annual Review of Vision Science | 2022 | | |
Synaptic transmission at the vestibular hair cells of amniotes | | Mukhopadhyay M, Pangrsic T | Molecular and Cellular Neuroscience | 2022 | | |
The Statistics of Circular Optimal Transport |
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Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs |
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Whole genome sequencing for newborns—The devil is in the details |
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GGPS1‐associated muscular dystrophy with and without hearing loss |
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Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study |
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Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease |
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Electrophysiological Characterization of Microbial Rhodopsins by Patch-Clamp Experiments | | Mager T | Methods in Molecular Biology | 2022 | | |
Imaging of Autonomous Bioluminescence Emission From Single Mammalian Cells | | Gregor C | Methods in Molecular Biology | 2022 | | |
Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices |
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Expansion microscopy at one nanometer resolution |
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Cryo-electron tomography reveals enrichment and identifies microtubule lumenal particles in neuronal differentiation |
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Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain |
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Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA A Rs and cytosolic gephyrin aggregation |
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A sequential two-step priming scheme reproduces diversity in synaptic strength and short-term plasticity |
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Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina |
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From Molecular to Functional Effects of Different Environmental Lead Exposure Paradigms |
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Structure of angiogenin dimer bound to double-stranded RNA |
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Roadmap for Optical Tweezers |
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From LUVs to GUVs - how to cover micrometer-sized pores with membranes |
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Aneuploidy in mammalian oocytes and the impact of maternal ageing | | Charalambous C, Webster A, Schuh M | Nature Reviews Molecular Cell Biology | 2022 | | |
Graded optogenetic activation of the auditory pathway for neural network analysis and hearing restoration |
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The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils |
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Impact of native-like lipid membranes on the architecture and contractility of actomyosin networks |
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There is no F in APC: Using physiological fluoride-free solutions for high throughput automated patch clamp experiments |
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In silico modeling for personalized stenting in aortic coarctation |
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A quantitative fluorescence-based approach to study mitochondrial protein import |
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Engineered skeletal muscle recapitulates human muscle development, regeneration and dystrophy |
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Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control |
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Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous Environment | | Corbet BP, Schlüter JM, Cotroneo ER, Crespi S, Simeth NA | European Journal of Organic Chemistry | 2022 | | |
Cochlear Hair Cell Innervation is Dependent on a Modulatory Function of Semaphorin‐3A | | Cantu‐Guerra HL, Papazian MR, (...), Coate TM | Developmental Dynamics | 2022 | | |
Mammalian oocytes store mRNAs in a mitochondria-associated membraneless compartment | | Cheng S, Altmeppen G, (...), Schuh M | Science | 2022 | | |
Dysferlin facilitates the de novo biogenesis of tubular membranes in hypertrophic remodelling |
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Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita |
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Graphene-Induced Energy Transfer for Quantitative Membrane Biophysics at Sub-Nanometer Resolution |
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Focused ion beam‐scanning electron microscopy links pathological myelin outfoldings to axonal changes in mice lacking Plp1 or Mag |
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Unbalanced Kantorovich-Rubinstein distance and barycenter for finitely supported measures: A statistical perspective |
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New Insights into the Proteolytic Regulation of the Structural Protein Junctophilin-2 by Calpain |
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Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones |
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Structures of transcription preinitiation complex engaged with the +1 nucleosome |
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Regulation of the mammalian-brain V-ATPase through ultraslow mode-switching | | Kosmidis E, Shuttle CG, (...), Stamou D | Nature | 2022 | | |
Editorial: Cardiac optogenetics: Using light to observe and excite the heart |
| Bruegmann T, Smith GL, Lehnart SE | Frontiers in Physiology | 2022 | | |
Targeting Mitochondrial Calcium Handling to Treat Atrial Fibrillation | | Voigt N, Maack C, Pronto JRD | Journal of the American College of Cardiology | 2022 | | |
Sampling effects and measurement overlap can bias the inference of neuronal avalanches |
| Pinheiro Neto J, Spitzner FP, Priesemann V | PLOS Computational Biology | 2022 | | |
Adventures and Advances in Time Travel With Induced Pluripotent Stem Cells and Automated Patch Clamp |
| Rosholm KR, Badone B, (...), Bell DC | Frontiers in Molecular Neuroscience | 2022 | | |
Artificial peptides to induce membrane denaturation and disruption and modulate membrane composition and fusion |
| Lāce I, Cotroneo ER, Hesselbarth N, Simeth NA | Journal of Peptide Science | 2022 | | |
Postmortem quantitative MRI disentangles histological lesion types in multiple sclerosis |
| Galbusera R, Bahn E, (...), Granziera C | Brain Pathology | 2022 | | |
Filter-based models of suppression in retinal ganglion cells: comparison and generalization across species and stimuli |
| Shahidi N, Rozenblit F, (...), Gollisch T | bioRxiv | 2022 | | |
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse |
| Hain PJH, Moser T | bioRxiv | 2022 | | |
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II |
| Rengachari S, Schilbach S, (...), Cramer P | Nature Structural & Molecular Biology | 2022 | | |
Free‐breathing myocardial T1 mapping using inversion‐recovery radial FLASH and motion‐resolved model‐based reconstruction |
| Wang X, Rosenzweig S, (...), Uecker M | Magnetic Resonance in Medicine | 2022 | | |
Somatic mosaicism in STAG2-associated cohesinopathies: Expansion of the genotypic and phenotypic spectrum |
| Schmidt J, Dreha-Kulaczewski S, (...), Wollnik B | Frontiers in Cell and Developmental Biology | 2022 | | |
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity |
| Stewart H, Lu Y, (...), Firth AE | bioRxiv | 2022 | | |
The 3D structure of lipidic fibrils of α-synuclein |
| Frieg B, Antonschmidt L, (...), Schröder GF | Nature Communications | 2022 | | |
Mono- and Intralink Filter (Mi-Filter) To Reduce False Identifications in Cross-Linking Mass Spectrometry Data |
| Chen X, Sailer C, (...), Stengel F | Analytical Chemistry | 2022 | | |
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain |
| Liu T, Stephan T, (...), Chen Z | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Cotranslational Biogenesis of Membrane Proteins in Bacteria |
| Mercier E, Wang X, Bögeholz LAK, Wintermeyer W, Rodnina MV | Frontiers in Molecular Biosciences | 2022 | | |
Expanding the spectrum of EEF1D neurodevelopmental disorders: Biallelic variants in the Guanine Exchange Domain | | Averdunk L, Al‐Thihli K, (...), Wieczorek D | Clinical Genetics | 2022 | | |
On the Fabrication and Characterization of Polymer-Based Waveguide Probes for Use in Future Optical Cochlear Implants |
| Helke C, Reinhardt M, (...), Reuter D | Materials | 2022 | | |
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
| Koss DJ, Erskine D, (...), Outeiro TF | Acta Neuropathologica Communications | 2022 | | |
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | eLife | 2022 | | |
Prion-like α-synuclein pathology in the brain of infants with Krabbe disease | | Hatton C, Ghanem SS, (...), Erskine D | Brain | 2022 | | |
The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation |
| Kleiber N, Lemus-Diaz N, (...), Bohnsack MT | Nature Communications | 2022 | | |
A junctional cAMP compartment regulates rapid Ca2+ signaling in atrial myocytes |
| Brandenburg S, Pawlowitz J, (...), Lehnart SE | Journal of Molecular and Cellular Cardiology | 2022 | | |
Fluorescence lifetime DNA-PAINT for multiplexed super-resolution imaging of cells |
| Oleksiievets N, Sargsyan Y, (...), Tsukanov R | Communications Biology | 2022 | | |
Age-dependent structural reorganization of utricular ribbon synapses |
| Michanski S, Henneck T, (...), Wichmann C | bioRxiv | 2022 | | |
The Role of Junctophilin Proteins in Cellular Function |
| Lehnart SE, Wehrens XH | Physiological Reviews | 2022 | | |
On the Uniqueness of Kantorovich Potentials |
| Staudt T, Hundrieser S, Munk A | arXiv | 2022 | | |
A Molecular Pump Facilitates Mechanical Adsorption Away from Equilibrium | | Simeth NA | Angewandte Chemie-International Edition | 2022 | | |
Dystrophin is a mechanical tension modulator |
| Hofemeier AD, Muenker TM, (...), Betz T | bioRxiv | 2022 | | |
Ovarian carcinoma immunoreactive antigen-like protein 2 (OCIAD2) is a novel complex III specific assembly factor in mitochondria |
| Chojnacka KJ, Elancheliyan P, (...), Chacińska A | Molecular Biology of the Cell | 2022 | | |
Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity | | Brás IC, Khani MH, (...), Outeiro TF | Journal of Parkinson's Disease | 2022 | | |
Piccolino regulates the architecture of the ribbon at cochlear inner hair cell synapses |
| Michanski S, Kapoor R, (...), Wichmann C | bioRxiv | 2022 | | |
Endogenous Levels of Alpha-Synuclein Modulate Seeding and Aggregation in Cultured Cells |
| Vasili E, Dominguez-Meijide A, (...), Outeiro TF | Molecular Neurobiology | 2022 | | |
Mechanism of spindle pole organization and instability in human oocytes | | So C, Menelaou K, (...), Schuh M | Science | 2022 | | |
Structural basis for safe and efficient energy conversion in a respiratory supercomplex |
| Kao W, Ortmann de Percin Northumberland C, (...), Hunte C | Nature Communications | 2022 | | |
Real‐time radial tagging for quantification of left ventricular torsion | | Mohammadi E, Nasiraei‐Moghaddam A, Uecker M | Magnetic Resonance in Medicine | 2022 | | |
Rethinking opsins |
| Feuda R, Menon AK, Göpfert MC | Molecular Biology and Evolution | 2022 | | |
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures |
| Gönenc II, Wolff A, (...), Wollnik B | Human Molecular Genetics | 2022 | | |
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds |
| Saha I, Yuste-Checa P, (...), Hipp MS | bioRxiv | 2022 | | |
Indole derivatives as core structural motifs in molecular organic photoactuators |
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Environmental enrichment enhances patterning and remodeling of synaptic nanoarchitecture as revealed by STED nanoscopy |
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Empirical Optimal Transport between Different Measures Adapts to Lower Complexity |
| Hundrieser S, Staudt T, Munk A | arXiv | 2022 | | |
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation |
| Torres-Garcia L, P. Domingues JM, (...), Li J | Scientific Reports | 2022 | | |
A new form of axonal pathology in a spinal model of neuromyelitis optica |
| Herwerth M, Kenet S, (...), Misgeld T | Brain | 2022 | | |
Phenotypic spectrum of BLM and RMI1–related Bloom syndrome |
| Gönenc II, Elcioglu NH, (...), Wollnik B | Clinical Genetics | 2022 | | |
Deep, Deep Learning with BART |
| Blumenthal M, Luo G, Schilling M, Holme HCM, Uecker M | arXiv | 2022 | | |
A Unifying Approach to Distributional Limits for Empirical Optimal Transport |
| Hundrieser S, Klatt M, Staudt T, Munk A | arXiv | 2022 | | |
White matter integrity in mice requires continuous myelin synthesis at the inner tongue |
| Meschkat M, Steyer AM, (...), Möbius W | Nature Communications | 2022 | | |
MemBrain: A Deep Learning-aided Pipeline for Automated Detection of Membrane Proteins in Cryo-electron Tomograms |
| Lamm L, Righetto RD, (...), Engel BD | bioRxiv | 2022 | | |
A novel single-cell RNA-sequencing approach and its applicability connecting genotype to phenotype in ageing disease |
| Shomroni O, Sitte M, (...), Salinas G | Scientific Reports | 2022 | | |
Colocalization of different neurotransmitter transporters on synaptic vesicles is sparse except for VGLUT1 and ZnT3 |
| Upmanyu N, Jin J, (...), Sambandan S | Neuron | 2022 | | |
Autosomal dominant non-syndromic hearing loss maps to DFNA33 (13q34) and co-segregates with splice and frameshift variants in ATP11A, a phospholipid flippase gene |
| Pater JA, Penney C, (...), Young T | Human Genetics | 2022 | | |
Modeling charge separation in charged nanochannels for single-molecule electrometry | | Enderlein J, Sakhapov D, Gregor I, Croci M, Karedla N | Journal of Chemical Physics | 2022 | | |
Methods for multiscale structural and functional analysis of the mammalian cochlea | | Vogl C, Neef J, Wichmann C | Molecular and Cellular Neuroscience | 2022 | | |
Glycation modulates alpha-synuclein fibrillization kinetics: a sweet spot for inhibition |
| Farzadfard A, König A, (...), Otzen DE | Journal of Biological Chemistry | 2022 | | |
Extracellular alpha-synuclein: Sensors, receptors, and responses |
| Domingues R, Sant’Anna R, da Fonseca ACC, Robbs BK, Foguel D, Outeiro TF | Neurobiology of Disease | 2022 | | |
Selective optogenetic control of Gq signaling using human Neuropsin |
| Wagdi A, Malan D, (...), Bruegmann T | Nature Communications | 2022 | | |
Roles and dynamics of 3-methylcytidine in cellular RNAs |
| Bohnsack KE, Kleiber N, Lemus-Diaz N, Bohnsack MT | Trends in Biochemical Sciences | 2022 | | |
Measuring photophysical transition rates with fluorescence correlation spectroscopy and antibunching |
| Sakhapov D, Gregor I, Karedla N, Enderlein J | arXiv | 2022 | | |
Flexible auditory training, psychophysics, and enrichment of common marmosets with an automated, touchscreen-based system |
| Calapai A, Cabrera-Moreno J, Moser T, Jeschke M | Nature Communications | 2022 | | |
Optimal transfer functions for bandwidth-limited imaging |
| Stallinga S, Radmacher N, Delon A, Enderlein J | Physical Review Research | 2022 | | |
The small aromatic compound SynuClean-D inhibits the aggregation and seeded polymerization of multiple α-synuclein strains |
| Peña-Díaz S, Pujols J, (...), Ventura S | Journal of Biological Chemistry | 2022 | | |
Transmural myocardial repair with engineered heart muscle in a rat model of heterotopic heart transplantation – A proof-of-concept study | | Jebran A, Tiburcy M, (...), Zimmermann W | Journal of Molecular and Cellular Cardiology | 2022 | | |
Tissue-resident memory CD8+ T cells cooperate with CD4+ T cells to drive compartmentalized immunopathology in the CNS | | Vincenti I, Page N, (...), Merkler D | Science Translational Medicine | 2022 | | |
Statistical analysis of random objects via metric measure Laplacians |
| Mordant G, Munk A | arXiv | 2022 | | |
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration |
| Luebben AV, Bender D, (...), Steinfeld R | Science Advances | 2022 | | |
The future of Parkinson’s disease research: A new paradigm of human-specific investigation is necessary… and possible |
| Cassotta M, Geerts H, (...), Hogberg HT | ALTEX-Alternatives to Animal Experimentation | 2022 | | |
Rapidly Signal‐enhanced Metabolites for Atomic Scale Monitoring of Living Cells with Magnetic Resonance |
| Ding Y, Korchak S, (...), Glöggler S | Chemistry–Methods | 2022 | | |
Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons |
| Riemenschneider H, Guo Q, (...), Edbauer D | EMBO Reports | 2022 | | |
Statistical Methods for Minimax Estimation in Linear Models with Unknown Design Over Finite Alphabets | | Behr M, Munk A | SIAM Journal on Mathematics of Data Science | 2022 | | |
Analyzing efficacy, stability, and safety of AAV-mediated optogenetic hearing restoration in mice |
| Bali B, Gruber-Dujardin E, Kusch K, Rankovic V, Moser T | Life Science Alliance | 2022 | | |
Increased cytosolic calcium buffering contributes to a cellular arrhythmogenic substrate in iPSC-cardiomyocytes from patients with dilated cardiomyopathy |
| Jung P, Seibertz F, (...), Voigt N | Basic Research in Cardiology | 2022 | | |
Optogenetics and electron tomography for structure-function analysis of cochlear ribbon synapses |
| Chakrabarti R, Jaime Tobón LM, (...), Wichmann C | bioRxiv | 2022 | | |
In silico modeling for personalized stenting in aortic coarctation |
| Ma D, Wang Y, Azhar M, Adler A, Steinmetz M, Uecker M | arXiv | 2022 | | |
IDH3γ serves as a redox switch that regulates mitochondrial energy metabolism and contractility in the heart under oxidative stress |
| Nanadikar M, Leon AV, (...), Katschinski D | Researchsquare | 2022 | | |
Fast Photoswitchable Molecular Prosthetics Control Neuronal Activity in the Cochlea |
| Garrido-Charles A, Huet A, (...), Gorostiza P | Journal of the American Chemical Society | 2022 | | |
Regulated targeting of the monotopic hairpin membrane protein Erg1 requires the GET pathway |
| Farkas A, Urlaub H, Bohnsack KE, Schwappach B | Journal of Cell Biology | 2022 | | |
Identification and optimization of channelrhodopsin variants for optogenetic hearing restoration |
| Zerche M, Moser T, Mager T | Laryngo-Rhino-Otologie 2022 | 2022 | | |
In vivo investigation of f-Chrimson variants for optogenetic hearing restoration |
| Wrobel C, Zerche M, Kusch K, Mager T, Moser T | Laryngo-Rhino-Otologie 2022 | 2022 | | |
Excited state lifetime modulation in semiconductor nanocrystals for super-resolution imaging |
| Ghosh S, Hollingsworth J, Gallea JI, Majumder S, Enderlein J, Chizhik A | Nanotechnology | 2022 | | |
Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair | | Tiburcy M, Meyer T, Satin P, Zimmermann W | Methods in Molecular Biology | 2022 | | |
A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution | | Elizarova S, Chouaib AA, (...), Daniel JA | Proceedings of the National Academy of Sciences of the United States of America | 2022 | | |
Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
| Yudovich S, Marzouqe A, (...), Weiss S | Biophysical Journal | 2022 | | |
Background calcium influx in arrhythmia: lead actor or extra? |
| Fakuade FE, Fauconnier J, Voigt N | Journal of Physiology-London | 2022 | | |
The relevance of synuclein autoantibodies as a biomarker for Parkinson's disease | | Garg P, Maass F, (...), Bähr M | Molecular and Cellular Neuroscience | 2022 | | |
Not the classical serendipity: does doxapram treat atrial fibrillation? |
| Liutkute A, Brundel BJ, Voigt N | Cardiovascular Research | 2022 | | |
Retinal receptive-field substructure: scaffolding for coding and computation |
| Zapp SJ, Nitsche S, Gollisch T | Trends in Neurosciences | 2022 | | |
Progressive frontal intraosseous lipoma: Detection of the mosaic AKT1 variant discloses Proteus syndrome |
| Schmidt J, Bremmer F, Brockmann K, Kaulfuß S, Wollnik B | Clinical Genetics | 2022 | | |
An iodine-containing probe as a tool for molecular detection in secondary ion mass spectrometry |
| Kabatas Glowacki S, Agüi-Gonzalez P, (...), Rizzoli SO | Chemical Communications | 2022 | | |
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
| Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H | Nucleic Acids Research | 2022 | | |
Effects of cryo-EM cooling on structural ensembles |
| Bock LV, Grubmüller H | Nature Communications | 2022 | | |
Isotropic three-dimensional dual-color super-resolution microscopy with metal-induced energy transfer |
| Thiele JC, Jungblut M, (...), Enderlein J | Science Advances | 2022 | | |
Measuring Photophysical Transition Rates with Fluorescence Correlation Spectroscopy and Antibunching | | Sakhapov D, Gregor I, Karedla N, Enderlein J | Journal of Physical Chemistry Letters | 2022 | | |
Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells |
| Xiong L, Tolen EA, (...), Schöler HR | eLife | 2022 | | |
Structural and mechanistic basis of RNA processing by protein-only ribonuclease P enzymes |
| Bhatta A, Hillen HS | Trends in Biochemical Sciences | 2022 | | |
Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes |
| Weninger G, Pochechueva T, (...), Lehnart SE | Scientific Reports | 2022 | | |
Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations |
| Buratti FA, Boeffinger N, (...), Fernández CO | Protein Science | 2022 | | |
Distinct roles of the meningeal layers in CNS autoimmunity | | Merlini A, Haberl M, (...), Odoardi F | Nature Neuroscience | 2022 | | |
MemBrain: A Deep Learning-aided Pipeline for Detection of Membrane Proteins in Cryo-electron Tomograms | | Lamm L, Righetto RD, (...), Engel BD | Computer Methods and Programs in Biomedicine | 2022 | | |
Rapid multi-plane phase-contrast microscopy reveals torsional dynamics in flagellar motion |
| Mojiri S, Isbaner S, (...), Enderlein J | Biomedical Optics Express | 2021 | | |
Tejaas: reverse regression increases power for detecting trans-eQTLs |
| Banerjee S, Simonetti FL, (...), Söding J | Genome Biology | 2021 | | |
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis |
| Kabinger F, Stiller C, (...), Cramer P | bioRxiv | 2021 | | |
Insights into the molecular mechanism of amyloid filament formation: Segmental folding of α-synuclein on lipid membranes |
| Antonschmidt L, Dervişoğlu R, (...), Griesinger C | Science Advances | 2021 | | |
Cryo-EM structure of mammalian RNA polymerase II in complex with human RPAP2 |
| Fianu I, Dienemann C, Aibara S, Schilbach S, Cramer P | Communications Biology | 2021 | | |
α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease |
| Stuendl A, Kraus T, (...), Schneider A | Movement Disorders | 2021 | | |
Multi-label in vivo STED microscopy by parallelized switching of reversibly switchable fluorescent proteins |
| Willig KI, Wegner W, Müller A, Calvet-Fournier V, Steffens H | Cell Reports | 2021 | | |
Transmembrane β‐peptide helices as molecular rulers at the membrane surface |
| Kloos M, Sharma A, Enderlein J, Diederichsen U | Journal of Peptide Science | 2021 | | |
Graphene- and metal-induced energy transfer for single-molecule imaging and live-cell nanoscopy with (sub)-nanometer axial resolution | | Ghosh A, Chizhik AI, Karedla N, Enderlein J | Nature Protocols | 2021 | | |
Stable but not rigid: Chronic in vivo STED nanoscopy reveals extensive remodeling of spines, indicating multiple drivers of plasticity |
| Steffens H, Mott AC, (...), Willig KI | Science Advances | 2021 | | |
Structure of RNA polymerase II pre-initiation complex at 2.9 Å defines initial DNA opening | | Schilbach S, Aibara S, Dienemann C, Grabbe F, Cramer P | Cell | 2021 | | |
Structural basis of nucleosome transcription mediated by Chd1 and FACT |
| Farnung L, Ochmann M, Engeholm M, Cramer P | Nature Structural & Molecular Biology | 2021 | | |
Radiative Rate Modulation Reveals Near‐Unity Quantum Yield of Graphene Quantum Dots |
| Ghosh S, Oleksiievets N, Enderlein J, Chizhik AI | Advanced Optical Materials | 2021 | | |
Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis |
| Bergner CG, Genc N, (...), Stadelmann C | Glia | 2021 | | |
Targeted metabolomics revealed changes in phospholipids during the development of neuroinflammation in Abcd1 tm1Kds mice and X-linked adrenoleukodystrophy patients |
| Kettwig M, Klemp H, (...), Gärtner J | Journal of Inherited Metabolic Disease | 2021 | | |
Dysfunction of RAB39B‐Mediated Vesicular Trafficking in Lewy Body Diseases |
| Koss DJ, Campesan S, Giorgini F, Outeiro TF | Movement Disorders | 2021 | | |
Analysis of patchclamp recordings: model-free multiscale methods and software |
| Pein F, Eltzner B, Munk A | European Biophysics Journal | 2021 | | |
Correction to: The Coding and Small Non-coding Hippocampal Synaptic RNAome |
| Epple R, Krüger D, (...), Fischer A | Molecular Neurobiology | 2021 | | |
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex | | Huang B, Guo Q, (...), Fernández-Busnadiego R | Structure | 2021 | | |
Pore-Spanning Plasma Membranes Derived from Giant Plasma Membrane Vesicles | | Teiwes NK, Mey I, Baumann PC, Strieker L, Unkelbach U, Steinem C | ACS Applied Materials & Interfaces | 2021 | | |
In situ architecture of neuronal α-Synuclein inclusions |
| Trinkaus VA, Riera-Tur I, (...), Fernández-Busnadiego R | Nature Communications | 2021 | | |
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
| Oberbeckmann E, Niebauer V, (...), Korber P | Nature Communications | 2021 | | |
IGF1 Receptor Regulates Upward Firing Rate Homeostasis via the Mitochondrial Calcium Uniporter |
| Katsenelson M, Shapira I, (...), Slutsky I | bioRxiv | 2021 | | |
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology |
| Kargapolova Y, Rehimi R, (...), Papantonis A | Nature Communications | 2021 | | |
Non‐negative blind deconvolution for signal processing in a CRISPR‐edited iPSC‐cardiomyocyte model of dilated cardiomyopathy | | Xu H, Wali R, (...), Ebert A | FEBS Letters | 2021 | | |
MINSTED fluorescence localization and nanoscopy |
| Weber M, Leutenegger M, (...), Hell SW | Nature Photonics | 2021 | | |
Structures of mammalian RNA polymerase II pre-initiation complexes | | Aibara S, Schilbach S, Cramer P | Nature | 2021 | | |
Astrocytes control the spiking of mouse visual cortex layer 5 pyramidal neurons |
| Sundaram SM, Garg P, Leßlich HM, Mathivanan S | Journal of Physiology-London | 2021 | | |
Multiple haplotype reconstruction from allele frequency data | | Pelizzola M, Behr M, Li H, Munk A, Futschik A | Nature Computational Science | 2021 | | |
Physics-based reconstruction methods for magnetic resonance imaging |
| Wang X, Tan Z, Scholand N, Roeloffs V, Uecker M | Philosophical Transactions of the Royal Society A Mathematical, Physical and Engineering Sciences | 2021 | | |
Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons |
| Riemenschneider H, Guo Q, (...), Edbauer D | bioRxiv | 2021 | | |
Sequence determinants of human gene regulatory elements |
| Sahu B, Hartonen T, (...), Taipale J | bioRxiv | 2021 | | |
RIM-Binding Protein 2 organizes Ca2+ channel topography and regulates release probability and vesicle replenishment at a fast central synapse |
| Butola T, Alvanos T, (...), Moser T | bioRxiv | 2021 | | |
Dimeric form of SARS-CoV-2 polymerase |
| Jochheim FA, Tegunov D, (...), Cramer P | bioRxiv | 2021 | | |
A fluorescent nanosensor paint reveals the heterogeneity of dopamine release from neurons at individual release sites |
| Elizarova S, Chouaib A, (...), Daniel J | bioRxiv | 2021 | | |
Cryo-electron tomography of native Drosophila tissues vitrified by plunge freezing |
| Bäuerlein FJ, Pastor-Pareja JC, Fernández-Busnadiego R | bioRxiv | 2021 | | |
Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel |
| Kolář MH, Nagy G, Kunkel J, Vaiana SM, Bock LV, Grubmüller H | bioRxiv | 2021 | | |
Super-resolution microscopy informs on the molecular architecture of alpha-synuclein inclusions in model systems and in the human brain |
| Weish P, Lazaro DF, (...), Outeiro TF | bioRxiv | 2021 | | |
Instant three color multi-plane fluorescence microscopy |
| Gregor I, Butkevich E, Enderlein J, Mojiri S | bioRxiv | 2021 | | |
Fast photoswitchable molecular prosthetics control neuronal activity in the cochlea |
| Garrido-Charles A, Huet A, (...), Gorostiza P | bioRxiv | 2021 | | |
Resolving the molecular architecture of the photoreceptor active zone by MINFLUX nanoscopy |
| Grabner CP, Jansen I, (...), Moser T | bioRxiv | 2021 | | |
Alpha-synuclein induces epigenomic dysregulation of glutamate signaling and locomotor pathways |
| Schaffner SL, Wassouf Z, (...), Kobor MS | bioRxiv | 2021 | | |
Structure of a transcribing RNA polymerase II–U1 snRNP complex | | Zhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer P | Science | 2021 | | |
A DNA-based optical force sensor for live-cell applications | | Jayachandran C, Ghosh A, (...), Schmidt CF | bioRxiv | 2021 | | |
Chromatin Accessibility of Human Mitral Valves and Functional Assessment of MVP Risk Loci |
| Kyryachenko S, Georges A, (...), Bouatia-Naji N | Circulation Research | 2021 | | |
Exercise Stress Real-Time Cardiac Magnetic Resonance Imaging for Noninvasive Characterization of Heart Failure With Preserved Ejection Fraction |
| Backhaus SJ, Lange T, (...), Schuster A | Circulation | 2021 | | |
Doxycycline Interferes With Tau Aggregation and Reduces Its Neuronal Toxicity |
| Medina L, González-Lizárraga F, (...), Socias SB | Frontiers in Aging Neuroscience | 2021 | | |
MPV17 Mutations Are Associated With a Quiescent Energetic Metabolic Profile |
| Jacinto S, Guerreiro P, (...), Outeiro TF | Frontiers in Cellular Neuroscience | 2021 | | |
Developing Fast, Red-Light Optogenetic Stimulation of Spiral Ganglion Neurons for Future Optical Cochlear Implants |
| Huet AT, Dombrowski T, Rankovic V, Thirumalai A, Moser T | Frontiers in Molecular Neuroscience | 2021 | | |
Posterior analysis of n in the binomial (n,p) problem with both parameters unknown -- with applications to quantitative nanoscopy |
| Schmidt-Hieber J, Schneider LF, Staudt T, Krajina A, Aspelmeier T, Munk A | arXiv | 2021 | | |
The ultrametric Gromov-Wasserstein distance |
| Mémoli F, Munk A, Wan Z, Weitkamp C | arXiv | 2021 | | |
Frame-constrained total variation regularization for white noise regression |
| del Álamo M, Li H, Munk A | Annals of Statistics | 2021 | | |
The Statistics of Circular Optimal Transport |
| Hundrieser S, Klatt M, Munk A | arXiv | 2021 | | |
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 | | Gregor C | bioRxiv | 2021 | | |
Limit Distributions and Sensitivity Analysis for Entropic Optimal Transport on Countable Spaces |
| Hundrieser S, Klatt M, Munk A | arXiv | 2021 | | |
Transport Dependency: Optimal Transport Based Dependency Measures |
| Nies TG, Staudt T, Munk A | arXiv | 2021 | | |
Loss-of-function variants in DNM1 cause a specific form of developmental and epileptic encephalopathy only in biallelic state |
| Yigit G, Sheffer R, (...), Brockmann K | Journal of Medical Genetics | 2021 | | |
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines | | Helm MS, Dankovich TM, (...), Rizzoli SO | Nature Neuroscience | 2021 | | |
Low-Expressing Synucleinopathy Mouse Models Based on Oligomer-Forming Mutations and C-Terminal Truncation of α-Synuclein |
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Oct4 primarily controls enhancer activity rather than accessibility |
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Posterior analysis of n in the binomial (n,p) problem with both parameters unknown—with applications to quantitative nanoscopy |
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Brain iron enrichment attenuates α‐synuclein spreading after injection of preformed fibrils |
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Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling. |
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Protein Phosphorylation in Depolarized Synaptosomes: Dissecting Primary Effects of Calcium from Synaptic Vesicle Cycling |
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What is resolution? A statistical minimax testing perspective on superresolution microscopy |
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Structure of the human Mediator–RNA polymerase II pre-initiation complex | | Rengachari S, Schilbach S, Aibara S, Dienemann C, Cramer P | Nature | 2021 | | |
Structural and functional insights into human tRNA guanine transgylcosylase | | Sievers K, Welp L, Urlaub H, Ficner R | RNA Biology | 2021 | | |
Biallelic variants in PCDHGC4 cause a novel neurodevelopmental syndrome with progressive microcephaly, seizures, and joint anomalies |
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isoSTED microscopy with water-immersion lenses and background reduction | | Siegmund R, Werner F, Jakobs S, Geisler C, Egner A | Biophysical Journal | 2021 | | |
Statistical spatial analysis for cryo-electron tomography |
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Photophysical properties and fluorescence lifetime imaging of exfoliated near-infrared fluorescent silicate nanosheets |
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CaMKII inhibition has dual effects on spontaneous Ca2+ release and Ca2+ alternans in ventricular cardiomyocytes from mice with a gain-of-function RyR2 mutation |
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Allosteric transcription stimulation by RNA polymerase II super elongation complex | | Chen Y, Vos SM, Dienemann C, Ninov M, Urlaub H, Cramer P | Molecular Cell | 2021 | | |
Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells |
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Structural basis of intron selection by U2 snRNP in the presence of covalent inhibitors |
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MFSD2A-associated primary microcephaly - Expanding the clinical and mutational spectrum of this ultra-rare disease | | Khuller K, Yigit G, (...), Kuechler A | European Journal of Medical Genetics | 2021 | | |
Mapping Activity-Dependent Quasi-Stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging |
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Advanced fluorescence correlation spectroscopy for studying biomolecular conformation |
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Organs-on-chip models for cardiovascular drug development |
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Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression |
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The structure of a dimeric form of SARS-CoV-2 polymerase |
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Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo |
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Differences in synaptic vesicle pool behavior between male and female hippocampal cultured neurons |
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Structural basis of RNA processing by human mitochondrial RNase P |
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Fibroblast Derived Human Engineered Connective Tissue for Screening Applications | | Santos GL, Meyer T, Tiburcy M, DeGrave A, Zimmermann W, Lutz S | Journal of Visualized Experiments | 2021 | | |
Structure of an inactive RNA polymerase II dimer |
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Structural basis of human transcription–DNA repair coupling |
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Cellular models and therapeutic perspectives in hypertrophic cardiomyopathy |
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H3 acetylation selectively promotes basal progenitor proliferation and neocortex expansion |
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RNF43 Pathogenic Germline Variant in a Family with Colorectal Cancer | | Mikaeel RR, Young JP, (...), Price TJ | Clinical Genetics | 2021 | | |
Simple Model for Encoding Natural Images by Retinal Ganglion Cells with Nonlinear Spatial Integration |
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Management of Metadata Types in Basic Cardiological Research |
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The bumpy road of FAIRification in practice |
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The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1 |
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Biallelic variants in YRDC cause a developmental disorder with progeroid features |
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Mapping protein interactions in the active TOM-TIM23 supercomplex |
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GMDS2021 ePoster and video teaser for DOI 10.3205/21gmds072 |
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Exercise as a model to identify microRNAs linked to human cognition: a role for microRNA-409 and microRNA-501 |
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Hierarchical folding of the catalytic core during mitochondrial ribosome biogenesis |
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Familial cleft tongue caused by a unique translation initiation codon variant in TP63 |
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Intracellular softening and increased viscoelastic fluidity during division |
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Label-free imaging of age-related cardiac structural changes in non-human primates using multiphoton nonlinear microscopy |
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An in vitro system to silence mitochondrial gene expression |
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A novel single-cell RNA-sequencing platform and its applicability connecting genotype to phenotype in ageing-disease |
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Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy |
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Instant three-color multiplane fluorescence microscopy |
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Structural basis of Integrator-mediated transcription regulation | | Fianu I, Chen Y, (...), Cramer P | Science | 2021 | | |
Effects of cryo-EM cooling on structural ensembles |
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Interferon-driven brain phenotype in a mouse model of RNaseT2 deficient leukoencephalopathy |
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Exfoliation and Optical Properties of Near-Infrared Fluorescent Silicate Nanosheets |
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Three-dimensional virtual histology of the cerebral cortex based on phase-contrast X-ray tomography |
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Alpha-Synuclein Antibody Characterization: Why Semantics Matters |
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Truncated titin proteins and titin haploinsufficiency are targets for functional recovery in human cardiomyopathy due to TTN mutations | | Fomin A, Gärtner A, (...), Linke WA | Science Translational Medicine | 2021 | | |
Understanding and treating paediatric hearing impairment |
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Inactivation of Fgf3 and Fgf4 within the Fgf3/Fgf4/Fgf15 gene cluster reveals their redundant requirement for mouse inner ear induction and embryonic survival | | Zelarayan L, Vendrell V, (...), Schimmang T | Developmental Dynamics | 2021 | | |
Multiscale Strategy to Resolve Stroma–Cardiac Fibroblast Interactions | | Zimmermann W | Circulation Research | 2021 | | |
Cnm1 mediates nucleus–mitochondria contact site formation in response to phospholipid levels |
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The TFAM-to-mtDNA ratio defines inner-cellular nucleoid populations with distinct activity levels |
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Postnatal expression of the lysine methyltransferase SETD1B is essential for learning and the regulation of neuron-enriched genes |
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Free-Breathing Myocardial T1 Mapping using Inversion-Recovery Radial FLASH and Motion-Resolved Model-Based Reconstruction |
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Mechanism of SARS-CoV-2 polymerase stalling by remdesivir |
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Three-dimensional virtual histology of the human hippocampus based on phase-contrast computed tomography |
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Aneuploidy in human eggs: contributions of the meiotic spindle |
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Forces, Kinetics, and Fusion Efficiency Altered by the Full-Length Synaptotagmin-1 -PI(4,5)P2 Interaction in Constrained Geometries | | Dietz J, Oelkers M, (...), Janshoff A | Nano Letters | 2021 | | |
Non-negative Matrix Factorization as a Tool to Distinguish Between Synaptic Vesicles in Different Functional States |
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Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
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Exploring early time points of vimentin assembly in flow by fluorescence fluctuation spectroscopy |
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Minimax detection of localized signals in statistical inverse problems |
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Epigenetic gene expression links heart failure to memory impairment |
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Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms |
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Global and local tension measurements in biomimetic skeletal muscle tissues reveals early mechanical homeostasis |
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Electronic laboratory notekeeping at the Göttingen Campus |
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Phase Separation during Germline Development |
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Super-resolution imaging: when biophysics meets nanophotonics |
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Regulation of a subset of release-ready vesicles by the presynaptic protein Mover |
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Endogenous Levels of Alpha-synuclein Modulate Seeding and Aggregation in Cultured Cells |
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NanoSIMS observations of mouse retinal cells reveal strict metabolic controls on nitrogen turnover |
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Maintaining mitochondrial ribosome function: The role of ribosome rescue and recycling factors |
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Free-Breathing Water, Fat, R⋆2 and B0 Field Mapping of the Liver Using Multi-Echo Radial FLASH and Regularized Model-based Reconstruction (MERLOT) |
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Isotropic Three-Dimensional Dual-Color Super-Resolution Microscopy with Metal-Induced Energy Transfer |
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Overloaded Adeno-Associated Virus as a Novel Gene Therapeutic Tool for Otoferlin-Related Deafness |
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Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity |
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Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea |
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Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging | | Raja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh A | Nano Letters | 2021 | | |
Role of GTPases in Driving Mitoribosome Assembly | | Maiti P, Lavdovskaia E, Barrientos A, Richter-Dennerlein R | Trends in Cell Biology | 2021 | | |
Mechanism of molnupiravir-induced SARS-CoV-2 mutagenesis |
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RIM-Binding Protein 2 Organizes Ca2+ Channel Topography and Regulates Release Probability and Vesicle Replenishment at a Fast Central Synapse |
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Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors |
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Molecular and functional architecture of striatal dopamine release sites | | Banerjee A, Imig C, (...), Kaeser PS | Neuron | 2021 | | |
Urinary Levels of SARS-CoV-2 Nucleocapsid Protein Associate With Risk of AKI and COVID-19 Severity: A Single-Center Observational Study |
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The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast synaptic vesicle fusion |
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Proteomic mapping of atrial and ventricular heart tissue in patients with aortic valve stenosis |
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3D virtual histopathology of cardiac tissue from Covid-19 patients based on phase-contrast X-ray tomography |
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Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms | | Moebel E, Martinez-Sanchez A, (...), Kervrann C | Nature Methods | 2021 | | |
Global kinome profiling reveals DYRK1A as critical activator of the human mitochondrial import machinery |
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Towards Visual Proteomics at High Resolution |
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Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission |
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Allosteric control of Ubp6 and the proteasome via a bidirectional switch |
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Two distinct mechanisms of RNA polymerase II elongation stimulation in vivo | | Žumer K, Maier KC, (...), Cramer P | Molecular Cell | 2021 | | |
Structures and implications of TBP–nucleosome complexes |
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Optimal transfer functions for bandwidth-limited imaging |
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Advanced Data Analysis for Fluorescence-Lifetime Single-Molecule Localization Microscopy |
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Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator |
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Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner |
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Conditional Loss of BAF (mSWI/SNF) Scaffolding Subunits Affects Specification and Proliferation of Oligodendrocyte Precursors in Developing Mouse Forebrain |
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Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus |
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A microRNA signature that correlates with cognition and is a target against cognitive decline |
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Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity |
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LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders |
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Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics |
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A mathematical model for electrical activity in pig atrial tissue |
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Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model |
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Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation |
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Small Molecule Fisetin Modulates Alpha–Synuclein Aggregation |
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Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease |
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Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation |
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Ectosomes and exosomes are distinct proteomic entities that modulate spontaneous activity in neuronal cells |
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Molecular bases of mitochondrial disorders |
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Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies |
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Impaired Exercise Tolerance in Repaired Tetralogy of Fallot Is Associated With Impaired Biventricular Contractile Reserve: An Exercise-Stress Real-Time Cardiovascular Magnetic Resonance Study |
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0753 Free-Breathing Liver Fat and R2* Mapping: Multi-Echo Radial FLASH and Model-based Reconstruction (MERLOT) |
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Genomic basis of syndromic short stature in an Algerian patient cohort | | Moosa S, Chentli F, (...), Wollnik B | American Journal of Medical Genetics Part A | 2021 | | |
Single-cell transcription profiles in Bloom syndrome patients link BLM deficiency with altered condensin complex expression signatures |
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Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering |
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Cell programming to protect the ischemic heart and limb |
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Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation |
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Author Correction: Deep learning improves macromolecule identification in 3D cellular cryo-electron tomograms |
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Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review |
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The RyR2-R2474S Mutation Sensitizes Cardiomyocytes and Hearts to Catecholaminergic Stress-Induced Oxidation of the Mitochondrial Glutathione Pool |
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Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer | | Mikaeel RR, Young JP, (...), Price TJ | Genes Chromosomes and Cancer | 2021 | | |
Correction to: Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
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Challenges facing quantitative large-scale optical super-resolution, and some simple solutions |
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Intranuclear immunostaining-based FACS protocol from embryonic cortical tissue |
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Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer |
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Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders |
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Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes |
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Transcriptionally active enhancers in human cancer cells |
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Combined scanning small-angle X-ray scattering and holography probes multiple length scales in cell nuclei |
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Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy |
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Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast |
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Stress-induced nuclear condensation of NELF drives transcriptional downregulation |
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Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.5 Å in cells |
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Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
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Monitoring mitochondrial translation in living cells |
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Asymmetric opening of the homopentameric 5-HT3A serotonin receptor in lipid bilayers |
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Emerging concepts in synucleinopathies |
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New Species Can Broaden Myelin Research: Suitability of Little Skate, Leucoraja erinacea |
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The Coding and Small Non-coding Hippocampal Synaptic RNAome |
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Transcription activation depends on the length of the RNA polymerase II C‐terminal domain |
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Post-transcriptional regulation by the exosome complex is required for cell survival and forebrain development via repression of P53 signaling |
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Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies |
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PolyQ expansion does not alter the Huntingtin-HAP40 complex |
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Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels |
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Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies |
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Two mechanisms drive pronuclear migration in mouse zygotes |
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Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy |
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RIM-Binding Proteins Are Required for Normal Sound-Encoding at Afferent Inner Hair Cell Synapses |
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The vesicle cluster as a major organizer of synaptic composition in the short-term and long-term |
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Network-driven discovery yields new insight into Shox2-dependent cardiac rhythm control | | Hoffmann S, Schmitteckert S, (...), Rappold G | Biochimica et Biophysica Acta-Gene Regulatory Mechanisms | 2021 | | |
Efficient RNA polymerase II pause release requires U2 snRNP function | | Caizzi L, Monteiro-Martins S, (...), Cramer P | Molecular Cell | 2021 | | |
Structural basis of GTPase-mediated mitochondrial ribosome biogenesis and recycling |
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Colocalization for super-resolution microscopy via optimal transport |
| Tameling C, Stoldt S, Stephan T, Naas J, Jakobs S, Munk A | Nature Computational Science | 2021 | | |
Origins and mechanisms leading to aneuploidy in human eggs |
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Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers |
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Presynaptic activity and protein turnover are correlated at the single-synapse level |
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Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications |
| Vanegas LJ, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk A | arXiv | 2021 | | |
Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex |
| Ulmke PA, Sakib MS, (...), Tuoc T | Stem Cell Reports | 2021 | | |
Structure and function of SARS-CoV-2 polymerase |
| Hillen HS | Current Opinion in Virology | 2021 | | |
The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3′-UTRs of yeast mitochondrial mRNAs |
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The structure of Prp2 bound to RNA and ADP-BeF3− reveals structural features important for RNA unwinding by DEAH-box ATPases |
| Hamann F, Zimmerningkat LC, (...), Ficner R | Acta Crystallographica Section D-Structural Biology | 2021 | | |
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding |
| Bartsch A, Ives CM, (...), Llabrés S | Biochimica et Biophysica Acta-Biomembranes | 2021 | | |
Multiscale photonic imaging of the native and implanted cochlea |
| Keppeler D, Kampshoff CA, (...), Moser T | Proceedings of the National Academy of Sciences of the United States of America | 2021 | | |
The Cdk8 kinase module regulates interaction of the Mediator complex with RNA polymerase II |
| Osman S, Mohammad E, (...), Cramer P | Journal of Biological Chemistry | 2021 | | |
Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo |
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Parental genome unification is highly error-prone in mammalian embryos |
| Cavazza T, Takeda Y, (...), Schuh M | Cell | 2021 | | |
Utility of red‐light ultrafast optogenetic stimulation of the auditory pathway |
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Tissue engineered heart repair from preclinical models to first-in-patient studies | | Zimmermann W | Current Opinion in Physiology | 2020 | | |
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea |
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Epigenetic gene-expression links heart failure to memory impairment |
| Islam R, Lbik D, (...), Fischer A | bioRxiv | 2020 | | |
Overarching control of autophagy and DNA damage response by CHD6 revealed by modeling a rare human pathology | | Kargapolova Y, Rehimi R, (...), Papantonis A | bioRxiv | 2020 | | |
Pixel hopping enables fast STED nanoscopy at low light dose |
| Vinçon B, Geisler C, Egner A | Optics Express | 2020 | | |
Light Microscopy of Mitochondria at the Nanoscale | | Jakobs S, Stephan T, Ilgen P, Brüser C | Annual Review of Biophysics | 2020 | | |
Nanoscale x-ray holotomography of human brain tissue with phase retrieval based on multienergy recordings |
| Robisch A, Eckermann M, Töpperwien M, van der Meer F, Stadelmann-Nessler C, Salditt T | Journal of Medical Imaging | 2020 | | |
Phase-contrast x-ray tomography of neuronal tissue at laboratory sources with submicron resolution |
| Eckermann M, Töpperwien M, Robisch A, van der Meer F, Stadelmann C, Salditt T | Journal of Medical Imaging | 2020 | | |
Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease |
| Töpperwien M, van der Meer F, Stadelmann C, Salditt T | Neuroimage | 2020 | | |
Multiscale Quantile Segmentation | | Vanegas LJ, Behr M, Munk A | Journal of the American Statistical Association | 2020 | | |
Structure of the transcription coactivator SAGA | | Wang H, Dienemann C, Stützer A, Urlaub H, Cheung ACM, Cramer P | Nature | 2020 | | |
Molecular signature of slowly expanding lesions in progressive multiple sclerosis |
| Jäckle K, Zeis T, (...), Brück W | Brain | 2020 | | |
Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative Nanoscopy | | Staudt T, Aspelmeier T, Laitenberger O, Geisler C, Egner A, Munk A | Statistical Science | 2020 | | |
The mammalian rod synaptic ribbon is essential for Cav channel facilitation and ultrafast fusion of the readily releasable pool of vesicles |
| Grabner CP, Moser T | bioRxiv | 2020 | | |
Stress- and ubiquitylation-dependent phase separation of the proteasome | | Yasuda S, Tsuchiya H, (...), Saeki Y | Nature | 2020 | | |
Molecular and functional architecture of striatal dopamine release sites |
| Banerjee A, Imig C, (...), Kaeser PS | bioRxiv | 2020 | | |
Choice of fluorophore affects dynamic DNA nanostructures |
| Jahnke K, Grubmüller H, Igaev M, Göpfrich K | bioRxiv | 2020 | | |
Ruler elements in chromatin remodelers set nucleosome array spacing and phasing |
| Oberbeckmann E, Niebauer V, (...), Korber P | bioRxiv | 2020 | | |
Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses |
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Emerging approaches for restoration of hearing and vision |
| Kleinlogel S, Vogl C, Jeschke M, Neef J, Moser T | Physiological Reviews | 2020 | | |
Kinetics of Loop Closure in Disordered Proteins: Theory vs Simulations vs Experiments | | Satija R, Das A, Mühle S, Enderlein J, Makarov DE | Journal of Physical Chemistry B | 2020 | | |
Wide-Field Fluorescence Lifetime Imaging of Single Molecules | | Oleksiievets N, Thiele JC, (...), Enderlein J | Journal of Physical Chemistry A | 2020 | | |
A Transcriptome Analysis Identifies Potential Preventive and Therapeutic Approaches Towards COVID-19 |
| Islam MR, Fischer A | preprints.org | 2020 | | |
Nucleosome-bound SOX2 and SOX11 structures elucidate pioneer factor function | | Dodonova SO, Zhu F, Dienemann C, Taipale J, Cramer P | Nature | 2020 | | |
Extracellular Vesicles Derived from Neural Progenitor Cells––a Preclinical Evaluation for Stroke Treatment in Mice |
| Zheng X, Zhang L, (...), Doeppner TR | Translational Stroke Research | 2020 | | |
What is resolution? A statistical minimax testing perspective on super-resolution microscopy |
| Kulaitis G, Munk A, Werner F | arXiv | 2020 | | |
Structure of replicating SARS-CoV-2 polymerase |
| Hillen HS, Kokic G, Farnung L, Dienemann C, Tegunov D, Cramer P | Nature | 2020 | | |
Elemental quantification and analysis of structural abnormalities in neurons from Parkinson’s-diseased brains by X-ray fluorescence microscopy and diffraction |
| Joppe K, Nicolas J, Grünewald TA, Eckermann M, Salditt T, Lingor P | Biomedical Optics Express | 2020 | | |
A second cohort of CHD3 patients expands the molecular mechanisms known to cause Snijders Blok-Campeau syndrome |
| Drivas TG, Li D, (...), Bhoj E | European Journal of Human Genetics | 2020 | | |
CTCF is dispensable for immune cell transdifferentiation but facilitates an acute inflammatory response | | Stik G, Vidal E, (...), Graf T | Nature Genetics | 2020 | | |
Large field-of-view scanning small-angle X-ray scattering of mammalian cells |
| Cassini C, Wittmeier A, Brehm G, Denz M, Burghammer M, Köster S | Journal of Synchrotron Radiation | 2020 | | |
Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation | | Vos SM, Farnung L, Linden A, Urlaub H, Cramer P | Nature Structural & Molecular Biology | 2020 | | |
Real-time cardiovascular magnetic resonance T1 and extracellular volume fraction mapping for tissue characterisation in aortic stenosis |
| Backhaus SJ, Lange T, (...), Schuster A | Journal of Cardiovascular Magnetic Resonance | 2020 | | |
MICOS assembly controls mitochondrial inner membrane remodeling and crista junction redistribution to mediate cristae formation |
| Stephan T, Brüser C, (...), Jakobs S | EMBO Journal | 2020 | | |
μLED-based optical cochlear implants for spectrally selective activation of the auditory nerve |
| Dieter A, Klein E, (...), Moser T | EMBO Molecular Medicine | 2020 | | |
The human box C/D snoRNA U3 is a miRNA source and miR-U3 regulates expression of sortin nexin 27 |
| Lemus-Diaz N, Ferreira RR, Bohnsack KE, Gruber J, Bohnsack MT | Nucleic Acids Research | 2020 | | |
A comparative analysis of the mobility of 45 proteins in the synaptic bouton |
| Reshetniak S, Ußling J, (...), Rizzoli SO | EMBO Journal | 2020 | | |
The Role of Alpha-Synuclein And Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
| Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B | preprints.org | 2020 | | |
Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture | | Chizhik AI, Chizhik AM, (...), Enderlein J | Methods in Molecular Biology | 2020 | | |
Multichannel optogenetic stimulation of the auditory pathway using microfabricated LED cochlear implants in rodents | | Keppeler D, Schwaerzle M, (...), Moser T | Science Translational Medicine | 2020 | | |
Remyelination in multiple sclerosis: from basic science to clinical translation | | Lubetzki C, Zalc B, Williams A, Stadelmann C, Stankoff B | Lancet Neurology | 2020 | | |
Reliable estimation of membrane curvature for cryo-electron tomography |
| Salfer M, Collado JF, Baumeister W, Fernández-Busnadiego R, Martínez-Sánchez A | PLOS Computational Biology | 2020 | | |
CG-SENSE revisited: Results from the first ISMRM reproducibility challenge |
| Maier O, Baete SH, (...), Knoll F | arXiv | 2020 | | |
Multicolor 3D MINFLUX nanoscopy of mitochondrial MICOS proteins |
| Pape JK, Stephan T, (...), Hell SW | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
The mRNA-Binding Protein RBM3 Regulates Activity Patterns and Local Synaptic Translation in Cultured Hippocampal Neurons |
| Sertel SM, von Elling-Tammen MS, Rizzoli SO | Journal of Neuroscience | 2020 | | |
Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control |
| Hu Y, Korovaichuk A, (...), Bringmann H | Genetics | 2020 | | |
Heterogeneous Idealization of Ion Channel Recordings - Open Channel Noise |
| Pein F, Bartsch A, Steinem C, Munk A | arXiv | 2020 | | |
Dopamine promotes the neurodegenerative potential of β‐synuclein |
| Raina A, Leite K, (...), Kügler S | Journal of Neurochemistry | 2020 | | |
Rosalind Franklin and the Advent of Molecular Biology |
| Cramer P | Cell | 2020 | | |
Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids |
| Zafeiriou M, Bao G, (...), Zimmermann W | Nature Communications | 2020 | | |
Structural Biology of RNA Polymerase II Transcription: 20 Years On | | Osman S, Cramer P | Annual Review of Cell and Developmental Biology | 2020 | | |
14-3-3 binding creates a memory of kinase action by stabilizing the modified state of phospholamban | | Menzel J, Kownatzki-Danger D, (...), Schwappach B | Science Signaling | 2020 | | |
Structural Basis of Tail-Anchored Membrane Protein Biogenesis by the GET Insertase Complex |
| Heimes M, Fiorentino F, (...), Sinning I | Molecular Cell | 2020 | | |
3D analysis of the myenteric plexus of the human bowel by X-ray phase-contrast tomography – a future method? |
| Peruzzi N, Veress B, (...), Ohlsson B | Scandinavian Journal of Gastroenterology | 2020 | | |
Investigating the Structure of Neurotoxic Protein Aggregates Inside Cells |
| Bäuerlein FJ, Fernández-Busnadiego R, Baumeister W | Trends in Cell Biology | 2020 | | |
Ultrastructural Imaging of Activity-Dependent Synaptic Membrane-Trafficking Events in Cultured Brain Slices |
| Imig C, López-Murcia FJ, (...), Cooper BH | Neuron | 2020 | | |
Neuropilin-1 facilitates SARS-CoV-2 cell entry and infectivity |
| Cantuti-Castelvetri L, Ojha R, (...), Simons M | Science | 2020 | | |
MOG-expressing teratoma followed by MOG-IgG-positive optic neuritis |
| Wildemann B, Jarius S, Franz J, Ruprecht K, Reindl M, Stadelmann C | Acta Neuropathologica | 2020 | | |
Optimistic search strategy: Change point detection for large-scale data via adaptive logarithmic queries |
| Kovacs S, Li H, Haubner L, Munk A, Bühlmann P | arXiv | 2020 | | |
Analysis of Patchclamp Recordings: Model-Free Multiscale Methods and Software |
| Pein F, Eltzner B, Munk A | CRAN | 2020 | | |
Quantitative analysis of hidden particles diffusing behind a scattering layer using speckle correlation |
| Sarkar A, Wang I, Enderlein J, Derouard J, Delon A | Optics Express | 2020 | | |
Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide | | Montiel V, Bella R, (...), Balligand J | Science Translational Medicine | 2020 | | |
Confocal Fluorescence-Lifetime Single-Molecule Localization Microscopy |
| Thiele JC, Helmerich DA, (...), Enderlein J | ACS Nano | 2020 | | |
Heterozygous truncating variants in SUFU cause congenital ocular motor apraxia |
| Schröder S, Li Y, (...), Brockmann K | Genetics in Medicine | 2020 | | |
Increased expression of myelin-associated genes in frontal cortex of SNCA overexpressing rats and Parkinson’s disease patients |
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3d phase‐contrast nanotomography of unstained human skin biopsies may identify morphological differences in the dermis and epidermis between subjects |
| Eckermann M, Peruzzi N, (...), Ohlsson B | Skin Research and Technology | 2020 | | |
Physics-based Reconstruction Methods for Magnetic Resonance Imaging |
| Wang X, Tan Z, Scholand N, Roeloffs V, Uecker M | arXiv | 2020 | | |
Variational multiscale nonparametric regression: Algorithms |
| del Alamo M, Li H, Munk A, Werner F | arXiv | 2020 | | |
3D virtual histology of human pancreatic tissue by multiscale phase-contrast X-ray tomography |
| Frohn J, Pinkert-Leetsch D, (...), Salditt T | Journal of Synchrotron Radiation | 2020 | | |
Defining the architecture of the human TIM22 complex by chemical crosslinking |
| Valpadashi A, Callegari S, (...), Rehling P | FEBS Letters | 2020 | | |
Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity |
| Ruhlandt D, Andresen M, (...), Chizhik AI | Communications Biology | 2020 | | |
Engineered Heart Muscle Models in Phenotypic Drug Screens | | Zimmermann W | Handb Exp Pharmacol | 2020 | | |
Pharmacological Modulators of Tau Aggregation and Spreading |
| Dominguez-Meijide A, Vasili E, Outeiro TF | Brain Sciences | 2020 | | |
Variational Multiscale Nonparametric Regression: Algorithms and Implementation |
| del Alamo M, Li H, Munk A, Werner F | Algorithms | 2020 | | |
Viral rhodopsins 1 are an unique family of light-gated cation channels |
| Zabelskii D, Alekseev A, (...), Gordeliy V | Nature Communications | 2020 | | |
From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease |
| Outeiro TF, Heutink P, Bezard E, Cenci AM | Movement Disorders | 2020 | | |
Efficient modeling of three-dimensional convection–diffusion problems in stationary flows |
| Thiele JC, Gregor I, Karedla N, Enderlein J | Physics of Fluids | 2020 | | |
Ion type and valency differentially drive vimentin tetramers into intermediate filaments or higher order assemblies |
| Denz M, Marschall M, Herrmann H, Köster S | Soft Matter | 2020 | | |
Intronic CRISPR Repair in a Preclinical Model of Noonan Syndrome–Associated Cardiomyopathy |
| Hanses U, Kleinsorge M, (...), Cyganek L | Circulation | 2020 | | |
Doubling the resolution of a confocal spinning-disk microscope using image scanning microscopy | | Qin S, Isbaner S, Gregor I, Enderlein J | Nature Protocols | 2020 | | |
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 |
| Meinhardt J, Radke J, (...), Heppner FL | Nature Neuroscience | 2020 | | |
A minimalist model to measure interactions between proteins and synaptic vesicles |
| Perego E, Reshetniak S, (...), Köster S | Scientific Reports | 2020 | | |
The evolution of the huntingtin-associated protein 40 (HAP40) in conjunction with huntingtin |
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Alpha‐synuclein oligomerization and aggregation: a model will always be a model |
| Outeiro TF | Journal of Neurochemistry | 2020 | | |
[11C]MODAG-001—towards a PET tracer targeting α-synuclein aggregates |
| Kuebler L, Buss S, (...), Herfert K | European Journal of Nuclear Medicine and Molecular Imaging | 2020 | | |
X-ray diffraction and second harmonic imaging reveal new insights into structural alterations caused by pressure-overload in murine hearts |
| Nicolas J, Khan A, (...), Salditt T | Scientific Reports | 2020 | | |
A sensory cell diversifies its output by varying Ca2+ influx‐release coupling among active zones |
| Özcete ÖD, Moser T | EMBO Journal | 2020 | | |
Cancer and Parkinson's Disease: Common Targets, Emerging Hopes | | Filippou PS, Outeiro TF | Movement Disorders | 2020 | | |
Small-molecule inhibitors of human mitochondrial DNA transcription |
| Bonekamp NA, Peter B, (...), Larsson N | Nature | 2020 | | |
An experimentally generated peptide database increases the sensitivity of XL-MS with complex samples | | Parfentev I, Schilbach S, Cramer P, Urlaub H | Journal of Proteomics | 2020 | | |
A nanobody-based fluorescent reporter reveals human α-synuclein in the cell cytosol |
| Gerdes C, Waal N, (...), Opazo F | Nature Communications | 2020 | | |
Lack of astrocytes hinders parenchymal oligodendrocyte precursor cells from reaching a myelinating state in osmolyte-induced demyelination |
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Integrator is a genome-wide attenuator of non-productive transcription | | Lykke-Andersen S, Žumer K, (...), Jensen TH | Molecular Cell | 2020 | | |
Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
| Jean P, Anttonen T, (...), Moser T | Nature Communications | 2020 | | |
Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes | | Seibertz F, Reynolds M, Voigt N | Journal of Visualized Experiments | 2020 | | |
Recent advances in cochlear hair cell nanophysiology: subcellular compartmentalization of electrical signaling in compact sensory cells |
| Effertz T, Moser T, Oliver D | Faculty Reviews | 2020 | | |
Molecular and cellular dynamics of the 26S proteasome |
| Sakata E, Eisele MR, Baumeister W | Biochimica et Biophysica Acta-Proteins and Proteomics | 2020 | | |
Multi‐Color, Bleaching‐Resistant Super‐Resolution Optical Fluctuation Imaging with Oligonucleotide‐based Exchangeable Fluorophores |
| Glogger M, Spahn C, Enderlein J, Heilemann M | Angewandte Chemie-International Edition | 2020 | | |
Post-translational modifications soften vimentin intermediate filaments |
| Kraxner J, Lorenz C, (...), Köster S | Nanoscale | 2020 | | |
Aplasia cutis congenita in a CDC42‐related developmental phenotype | | Schnabel F, Kamphausen SB, Funke R, Kaulfuß S, Wollnik B, Zenker M | American Journal of Medical Genetics Part A | 2020 | | |
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes |
| Lavdovskaia E, Denks K, (...), Richter-Dennerlein R | Nucleic Acids Research | 2020 | | |
Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees |
| Heinemann F, Munk A, Zemel Y | arXiv | 2020 | | |
Structural basis of nucleosome transcription mediated by Chd1 and FACT |
| Farnung L, Ochmann M, Engeholm M, Cramer P | bioRxiv | 2020 | | |
Cellular and mitochondrial mechanisms of atrial fibrillation |
| Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N | Basic Research in Cardiology | 2020 | | |
The Coding And Small-Non-Coding Hippocampal Synaptic RNAome |
| Epple R, Krüger D, (...), Fischer A | bioRxiv | 2020 | | |
Drosophila Mechanosensory Transduction | | Hehlert P, Zhang W, Göpfert MC | Trends in Neurosciences | 2020 | | |
Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity |
| Medina L, González-Lizárraga F, (...), Socias SB | bioRxiv | 2020 | | |
CG‐SENSE revisited: Results from the first ISMRM reproducibility challenge |
| Maier O, Baete SH, (...), Knoll F | Magnetic Resonance in Medicine | 2020 | | |
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R |
| Dankovich TM, Kaushik R, (...), Rizzoli SO | bioRxiv | 2020 | | |
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2 |
| Kreutzberger AJ, Kiessling V, (...), Tamm LK | eLife | 2020 | | |
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo |
| Dominguez-Meijide A, Parrales V, (...), Outeiro TF | bioRxiv | 2020 | | |
Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes |
| Dijkman PM, Muñoz-García JC, (...), Watts A | Science Advances | 2020 | | |
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding |
| Bartsch A, Ives C, (...), Llabrés S | bioRxiv | 2020 | | |
Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium Current | | Tomsits P, Schüttler D, Kääb S, Clauss S, Voigt N | Journal of Visualized Experiments | 2020 | | |
Connexin hemichannels in atrial fibrillation: orphaned and irrelevant? |
| Fakuade FE, Tomsits P, Voigt N | Cardiovascular Research | 2020 | | |
Environmental enrichment enhances precision and remodeling speed of synaptic nanoarchitecture revealed by crosstalk free two-color in vivo STED nanoscopy |
| Wegner W, Steffens H, Gregor C, Wolf F, Willig KI | bioRxiv | 2020 | | |
Heterogeneous Idealization of Ion Channel Recordings – Open Channel Noise |
| Pein F, Bartsch A, Steinem C, Munk A | IEEE Transactions on NanoBioscience | 2020 | | |
Time-resolved MIET measurements of blood platelet spreading and adhesion |
| Zelená A, Isbaner S, (...), Köster S | Nanoscale | 2020 | | |
X-Ray Structural Analysis of Single Adult Cardiomyocytes: Tomographic Imaging and Microdiffraction |
| Reichardt M, Neuhaus C, Nicolas J, Bernhardt M, Toischer K, Salditt T | Biophysical Journal | 2020 | | |
Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations |
| Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C | International Journal of Molecular Sciences | 2020 | | |
Stable but not rigid: Long-term in vivo STED nanoscopy uncovers extensive remodeling of stable spines and indicates multiple drivers of structural plasticity |
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Model‐based reconstruction for simultaneous multi‐slice mapping using single‐shot inversion‐recovery radial FLASH |
| Wang X, Rosenzweig S, Scholand N, Holme HCM, Uecker M | Magnetic Resonance in Medicine | 2020 | | |
Seeded intervals and noise level estimation in change point detection: a discussion of Fryzlewicz (2020) |
| Kovács S, Li H, Bühlmann P | Journal of the Korean Statistical Society | 2020 | | |
Multiple Haplotype Reconstruction from Allele Frequency Data |
| Pelizzola M, Behr M, Li H, Munk A, Futschik A | bioRxiv | 2020 | | |
Premature aging disorders: A clinical and genetic compendium |
| Schnabel F, Kornak U, Wollnik B | Clinical Genetics | 2020 | | |
GROMEX: A Scalable and Versatile Fast Multipole Method for Biomolecular Simulation |
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Parental genome unification is highly erroneous in mammalian embryos |
| Cavazza T, Politi AZ, (...), Schuh M | bioRxiv | 2020 | | |
Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases |
| Menezes R, Foito A, (...), Santos CN | Antioxidants | 2020 | | |
Emission States Variation of Single Graphene Quantum Dots | | Ghosh S, Oleksiievets N, Enderlein J, Chizhik AI | Journal of Physical Chemistry Letters | 2020 | | |
Presynaptic Physiology of Cochlear Inner Hair Cells | | Moser T | The Senses: A Comprehensive Reference | 2020 | | |
3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography |
| Eckermann M, Frohn J, (...), Salditt T | eLife | 2020 | | |
The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders |
| Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B | International Journal of Molecular Sciences | 2020 | | |
Correction: Circumvention of common labelling artefacts using secondary nanobodies |
| Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F | Nanoscale | 2020 | | |
In situ architecture of neuronal α-Synuclein inclusions |
| Trinkaus VA, Riera-Tur I, (...), Fernández-Busnadiego R | bioRxiv | 2020 | | |
SETD1B controls cognitive function via cell type specific regulation of neuronal identity genes |
| Michurina A, Sakib S, (...), Fischer A | bioRxiv | 2020 | | |
RAB39B is redistributed in dementia with Lewy bodies and is sequestered within aβ plaques and Lewy bodies |
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Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization |
| Dominguez-Meijide A, Vasili E, (...), Outeiro TF | Scientific Reports | 2020 | | |
Local translation in synaptic mitochondria influences synaptic transmission |
| Yousefi R, Fornasiero EF, (...), Pacheu-Grau D | bioRxiv | 2020 | | |
Three-dimensional beating dynamics of Chlamydomonas flagella |
| Mojiri S, Isbaner S, (...), Enderlein J | bioRxiv | 2020 | | |
Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels |
| Bonnin EA, Rizzoli SO | Frontiers in Behavioral Neuroscience | 2020 | | |
Minimax estimation in linear models with unknown design over finite alphabets |
| Behr M, Munk A | arXiv | 2020 | | |
Gromov-Wasserstein Distance based Object Matching: Asymptotic Inference |
| Weitkamp CA, Proksch K, Tameling C, Munk A | arXiv | 2020 | | |
Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations |
| Farnung L, Ochmann M, Cramer P | eLife | 2020 | | |
Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis |
| Ganapathi M, Argyriou L, (...), Wollnik B | Human Genetics | 2020 | | |
Fluorescence polarization filtering for accurate single molecule localization |
| Nevskyi O, Tsukanov R, Gregor I, Karedla N, Enderlein J | APL Photonics | 2020 | | |
Editorial commentary: Challenges to heart repair with pluripotent stem cell-derived cardiomyocytes | | Zimmermann W | Trends in Cardiovascular Medicine | 2020 | | |
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.7 Å inside cells |
| Tegunov D, Xue L, Dienemann C, Cramer P, Mahamid J | bioRxiv | 2020 | | |
Generation of Engineered Human Myocardium in a Multi-well Format |
| Tiburcy M, Meyer T, Liaw NY, Zimmermann W | STAR Protocols | 2020 | | |
Empirical Regularized Optimal Transport: Statistical Theory and Applications |
| Klatt M, Tameling C, Munk A | SIAM Journal on Mathematics of Data Science | 2020 | | |
NETT: solving inverse problems with deep neural networks |
| Li H, Schwab J, Antholzer S, Haltmeier M | Inverse Problems | 2020 | | |
Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system |
| Jablonski L, Harczos T, (...), Moser T | bioRxiv | 2020 | | |
19th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products) | | Cavero I, Seimetz D, Koziel D, Zimmermann W, Holzgrefe HH | Expert Opinion on Drug Safety | 2020 | | |
Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis |
| Puls M, Beuthner BE, (...), Hasenfuß G | European Heart Journal | 2020 | | |
Tomographic STED microscopy |
| Krüger J, Keller-Findeisen J, Geisler C, Egner A | Biomedical Optics Express | 2020 | | |
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome |
| Ufartes R, Berger H, (...), Pauli S | Human Genetics | 2020 | | |
Circumvention of common labelling artefacts using secondary nanobodies |
| Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F | Nanoscale | 2020 | | |
Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering |
| Komorowski K, Schaeper J, (...), Salditt T | Soft Matter | 2020 | | |
Testing for dependence on tree structures |
| Behr M, Ansari MA, Munk A, Holmes C | Proceedings of the National Academy of Sciences of the United States of America | 2020 | | |
White matter integrity requires continuous myelin synthesis at the inner tongue |
| Meschkat M, Steyer AM, (...), Möbius W | bioRxiv | 2020 | | |
A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria |
| Linden A, Deckers M, (...), Urlaub H | Molecular & Cellular Proteomics | 2020 | | |
Towards the optical cochlear implant: optogenetic approaches for hearing restoration |
| Dieter A, Keppeler D, Moser T | EMBO Molecular Medicine | 2020 | | |
Human RAD50 deficiency: Confirmation of a distinctive phenotype |
| Ragamin A, Yigit G, (...), Mancini GMS | American Journal of Medical Genetics Part A | 2020 | | |
Multi-scale X-ray phase-contrast tomography of murine heart tissue |
| Reichardt M, Frohn J, Khan A, Alves F, Salditt T | Biomedical Optics Express | 2020 | | |
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome | | Wagner FR, Dienemann C, (...), Cramer P | Nature | 2020 | | |
Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT |
| Reichardt M, Töpperwien M, Khan A, Alves F, Salditt T | Journal of Medical Imaging | 2020 | | |
Seeded Binary Segmentation: A general methodology for fast and optimal change point detection |
| Kovács S, Li H, Bühlmann P, Munk A | arXiv | 2020 | | |
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control |
| Rathjens FS, Blenkle A, (...), Zafeiriou M | Cardiovascular Research | 2020 | | |
JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties | | Fonseca-Fonseca LA, da Silva VDA, (...), Núñez-Figueredo Y | Neurotoxicology | 2020 | | |
Live-cell STED microscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | bioRxiv | 2019 | | |
Live-cell STED nanoscopy of mitochondrial cristae |
| Stephan T, Roesch A, Riedel D, Jakobs S | Scientific Reports | 2019 | | |
Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity | | Schaefer T, Riera-Tur I, (...), Dudanova I | bioRxiv | 2019 | | |
Macromolecular and electrical coupling between inner hair cells in the rodent cochlea |
| Jean P, Anttonen T, (...), Moser T | bioRxiv | 2019 | | |
The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype |
| Yigit G, Saida K, (...), Altmüller J | Human Mutation | 2019 | | |
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation | | Berulava T, Buchholz E, (...), Toischer K | European Journal of Heart Failure | 2019 | | |
Metal-induced energy transfer |
| Gregor I, Chizhik A, Karedla N, Enderlein J | Nanophotonics | 2019 | | |
MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex |
| Wang C, Richter‐Dennerlein R, (...), Rehling P | EMBO reports | 2019 | | |
A combined miRNA-piRNA signature to detect Alzheimer's disease |
| Jain G, Stuendl A, (...), Fischer A | Translational Psychiatry | 2019 | | |
Modeling Fluorescence Correlation Spectroscopy through an aberrating sphere |
| Ruhlandt D, Katti A, Derouard J, Delon A, Enderlein J | arXiv | 2019 | | |
Empirical optimal transport on countable metric spaces: Distributional limits and statistical applications | | Tameling C, Sommerfeld M, Munk A | Annals of Applied Probability | 2019 | | |
Circumvention of common labeling artifacts using secondary nanobodies |
| Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F | bioRxiv | 2019 | | |
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers |
| Saravanan MS, Ryazanov S, (...), Killian JA | Scientific Reports | 2019 | | |
Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta | | Moosa S, Yamamoto GL, (...), Netzer C | American Journal of Human Genetics | 2019 | | |
Graphene-based metal-induced energy transfer for sub-nanometre optical localization | | Ghosh A, Sharma A, (...), Enderlein J | Nature Photonics | 2019 | | |
Testing for dependence on tree structures |
| Behr M, Ansari MA, Munk A, Holmes C | bioRxiv | 2019 | | |
Eukaryotic Transcription Turns 50 |
| Cramer P | Cell | 2019 | | |
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau |
| Brendel M, Deussing M, (...), Rominger A | Alzheimers Research & Therapy | 2019 | | |
Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model |
| Wegrzynowicz M, Bar-On D, (...), Spillantini MG | Acta Neuropathologica | 2019 | | |
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome |
| Wagner FR, Dienemann C, (...), Cramer P | bioRxiv | 2019 | | |
Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes |
| Hillen HS, Bartuli J, (...), Cramer P | Cell | 2019 | | |
Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity |
| Collado J, Kalemanov M, (...), Fernández-Busnadiego R | Developmental Cell | 2019 | | |
Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes |
| Grimm C, Hillen HS, (...), Fischer U | Cell | 2019 | | |
Mutation-induced alterations of intra-filament subunit organization in vimentin filaments revealed by SAXS |
| Brennich ME, Vainio U, Wedig T, Bauch S, Herrmann H, Köster S | Soft Matter | 2019 | | |
A mass spectrometry workflow for measuring protein turnover rates in vivo | | Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF | Nature Protocols | 2019 | | |
Multiscale quantile segmentation |
| Vanegas LJ, Behr M, Munk A | arXiv | 2019 | | |
The essential histogram | | Li H, Munk A, Sieling H, Walther G | Biometrika | 2019 | | |
Loop formation and translational diffusion of intrinsically disordered proteins | | Mühle S, Zhou M, Ghosh A, Enderlein J | Physical Review E | 2019 | | |
The Essential Histogram |
| Li H, Munk A, Sieling H, Walther G | arXiv | 2019 | | |
Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding | | Wang H, Farnung L, Dienemann C, Cramer P | Nature Structural & Molecular Biology | 2019 | | |
11C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier |
| Maurer A, Leonov A, (...), Griesinger C | ChemMedChem | 2019 | | |
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43 |
| Keihani S, Kluever V, (...), Fornasiero EF | Science Advances | 2019 | | |
Sharing Data from Molecular Simulations | | Abraham M, Apostolov R, (...), Zhmurov A | Journal of Chemical Information and Modeling | 2019 | | |
Dynamic instability of clathrin assembly provides proofreading control for endocytosis |
| Chen Y, Yong J, (...), Wu M | Journal of Cell Biology | 2019 | | |
Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography |
| Töpperwien M, Markus A, Alves F, Salditt T | Neuroimage | 2019 | | |
Organization and regulation of gene transcription | | Cramer P | Nature | 2019 | | |
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation |
| Alsina KM, Hulsurkar M, (...), Wehrens XH | Circulation | 2019 | | |
Molecular contribution function in RESOLFT nanoscopy |
| Frahm L, Keller-Findeisen J, (...), Hell SW | Optics Express | 2019 | | |
Frame-constrained Total Variation Regularization for White Noise Regression |
| del Álamo M, Li H, Munk A | arXiv | 2019 | | |
High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB |
| Bartsch A, Llabrés S, (...), Steinem C | Scientific Reports | 2019 | | |
Multiscale change-point segmentation: beyond step functions |
| Li H, Guo Q, Munk A | Electronic Journal of Statistics | 2019 | | |
A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice |
| Al‐Moyed H, Cepeda AP, Jung S, Moser T, Kügler S, Reisinger E | EMBO Molecular Medicine | 2018 | | |
The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain |
| Mandad S, Rahman R, (...), Fornasiero EF | Scientific Reports | 2018 | | |
Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy |
| Heras‐Garvin A, Weckbecker D, (...), Stefanova N | Movement Disorders | 2018 | | |