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Publication

Property	Value
Working Groups	RG Fischer
Subproject	None
Open Access	Yes
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	36758798
DOI	10.1016/j.jcmgh.2023.01.015
Publication Year	2023
Title	NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming
Journal	Cellular and Molecular Gastroenterology and Hepatology
ISSN	2352-345X
eISSN	2352-345X
URL	http://dx.doi.org/10.1016/j.jcmgh.2023.01.015
Pages	1219-1246
Issue	5
Volume	15
Journal Abbreviation	Cell Mol Gastroenterol Hepatol
Authors	Zhang Z, Wang X, Hamdan FH, Likhobabina A, Patil S, Aperdannier L, Sen M, Traub J, Neesse A, Fischer A, Papantonis A, Singh SK, Ellenrieder V, Johnsen SA, Hessmann E
First Author	Zhang Z
Last Author	Hessmann E

External Resources

gro-2/122269http://resolver.sub.uni-goettingen.de/purl?gro-2/122269 GRO.publications identifier

informat...028467https://www.informatics.jax.org/strain/MGI:3028467 MGI identifier (MGI:3028467, C57BL/6J)

GCF_000001405.13https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_000001405.13 NCBI Datasets Genome (GCF_000001405.13, human genome)

GCF_000001635.18https://www.ncbi.nlm.nih.gov/datasets/genome/GCF_000001635.18 NCBI Datasets Genome (GCF_000001635.18, mouse genome)

GSE166329https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166329 NCBI GEO identifier (GSE166329)

GSE166330https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166330 NCBI GEO identifier (GSE166330)

GSE166331https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166331 NCBI GEO identifier (GSE166331)

GSE166333https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE166333 NCBI GEO identifier (GSE166333)

GSE218822https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218822 NCBI GEO identifier (GSE218822)

GSM982509https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM982509 NCBI GEO identifier (GSM982509)

GSM982511https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSM982511 NCBI GEO identifier (GSM982511)

0000-0001-7440-1075https://orcid.org/0000-0001-7440-1075 ORCID identifier (Xin Wang)

0000-0003-2455-2435https://orcid.org/0000-0003-2455-2435 ORCID identifier (Feda H Hamdan)

0000-0001-8546-1161https://orcid.org/0000-0001-8546-1161 ORCID identifier (Andre Fischer)

0000-0001-7551-1073https://orcid.org/0000-0001-7551-1073 ORCID identifier (Argyris Papantonis)

0000-0002-5725-4058https://orcid.org/0000-0002-5725-4058 ORCID identifier (Shiv K Singh)

0000-0001-9981-8571https://orcid.org/0000-0001-9981-8571 ORCID identifier (Volker Ellenrieder)

0000-0003-1198-5805https://orcid.org/0000-0003-1198-5805 ORCID identifier (Steven A Johnsen)

0000-0002-9462-1291https://orcid.org/0000-0002-9462-1291 ORCID identifier (Elisabeth Hessmann)

043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)

00f2yqf98https://ror.org/00f2yqf98 ROR identifier (00f2yqf98, Hannover Medical School)

02qp3tb03https://ror.org/02qp3tb03 ROR identifier (02qp3tb03, Mayo Clinic)

05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, Universitätsmedizin Göttingen)

AB_262011https://scicrunch.org/resolver/AB_262011 SciCrunch identifier (RRID:AB_262011, β-actin)

AB_626668https://scicrunch.org/resolver/AB_626668 SciCrunch identifier (RRID:AB_626668, amylase)

AB_2637010https://scicrunch.org/resolver/AB_2637010 SciCrunch identifier (RRID:AB_2637010, ARID1A)

AB_397581https://scicrunch.org/resolver/AB_397581 SciCrunch identifier (RRID:AB_397581, E-Cadherin)

AB_2174426https://scicrunch.org/resolver/AB_2174426 SciCrunch identifier (RRID:AB_2174426, CD45)

AB_2281021https://scicrunch.org/resolver/AB_2281021 SciCrunch identifier (RRID:AB_2281021, cytokeratin 19)

AB_10920395https://scicrunch.org/resolver/AB_10920395 SciCrunch identifier (RRID:AB_10920395, EGFR)

AB_732110https://scicrunch.org/resolver/AB_732110 SciCrunch identifier (RRID:AB_732110, phosphor-EGFR (Y1068))

AB_2637079https://scicrunch.org/resolver/AB_2637079 SciCrunch identifier (RRID:AB_2637079, H3K27ac)

AB_2885844https://scicrunch.org/resolver/AB_2885844 SciCrunch identifier (RRID:AB_2885844, H3K27ac)

AB_2295297https://scicrunch.org/resolver/AB_2295297 SciCrunch identifier (RRID:AB_2295297, HDAC1)

AB_331563https://scicrunch.org/resolver/AB_331563 SciCrunch identifier (RRID:AB_331563, histone H3)

AB_330924https://scicrunch.org/resolver/AB_330924 SciCrunch identifier (RRID:AB_330924, HRP α-mouse)

AB_2722553https://scicrunch.org/resolver/AB_2722553 SciCrunch identifier (RRID:AB_2722553, mouse IgG)

AB_2722554https://scicrunch.org/resolver/AB_2722554 SciCrunch identifier (RRID:AB_2722554, rabbit IgG)

AB_330744https://scicrunch.org/resolver/AB_330744 SciCrunch identifier (RRID:AB_330744, p44/42 MAPK (ErK1/2))

AB_331772https://scicrunch.org/resolver/AB_331772 SciCrunch identifier (RRID:AB_331772, phospho-p44/42 MAPK (ErK1/2))

AB_2798639https://scicrunch.org/resolver/AB_2798639 SciCrunch identifier (RRID:AB_2798639, MIST1)

AB_448901https://scicrunch.org/resolver/AB_448901 SciCrunch identifier (RRID:AB_448901, NFATc1)

AB_2152503https://scicrunch.org/resolver/AB_2152503 SciCrunch identifier (RRID:AB_2152503, NFATc1)

AB_303308https://scicrunch.org/resolver/AB_303308 SciCrunch identifier (RRID:AB_303308, NFATc1)

Addgene_39311https://scicrunch.org/resolver/Addgene_39311 SciCrunch identifier (RRID:Addgene_39311, pcDNA6-V5/His-ARID1A)

Addgene_48138https://scicrunch.org/resolver/Addgene_48138 SciCrunch identifier (RRID:Addgene_48138, pSpCas9(BB)-2A-GFP (PX458))

Addgene_199743https://scicrunch.org/resolver/Addgene_199743 SciCrunch identifier (RRID:Addgene_199743, pMCV)

CVCL_3481https://scicrunch.org/resolver/CVCL_3481 SciCrunch identifier (RRID:CVCL_3481, 266-6)

CVCL_UY60https://scicrunch.org/resolver/CVCL_UY60 SciCrunch identifier (RRID:CVCL_UY60, KPC)

CVCL_0384https://scicrunch.org/resolver/CVCL_0384 SciCrunch identifier (RRID:CVCL_0384, L3.6pl)

SCR_019715https://scicrunch.org/resolver/SCR_019715 SciCrunch identifier (RRID:SCR_019715, Bioanalyzer 2100)

SCR_016368https://scicrunch.org/resolver/SCR_016368 SciCrunch identifier (RRID:SCR_016368, Bowtie2)

SCR_014551https://scicrunch.org/resolver/SCR_014551 SciCrunch identifier (RRID:SCR_01455, cellSens software)

SCR_001647https://scicrunch.org/resolver/SCR_001647 SciCrunch identifier (RRID:SCR_001647, Cuffdiff)

SCR_015687https://scicrunch.org/resolver/SCR_015687 SciCrunch identifier (RRID:SCR_015687, DESeq2)

SCR_012918https://scicrunch.org/resolver/SCR_012918 SciCrunch identifier (RRID: SCR_012918, DiffBind)

SCR_001575https://scicrunch.org/resolver/SCR_001575 SciCrunch identifier (RRID:SCR_001575, Enrichr)

SCR_014583https://scicrunch.org/resolver/SCR_014583 SciCrunch identifier (RRID:SCR_014583, FastQC)

SCR_006281https://scicrunch.org/resolver/SCR_006281 SciCrunch identifier (RRID:SCR_006281, Galaxy|Europe platform)

SCR_014601https://scicrunch.org/resolver/SCR_014601 SciCrunch identifier (RRID:SCR_014601, ggplot2)

SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

SCR_005807https://scicrunch.org/resolver/SCR_005807 SciCrunch identifier (RRID:SCR_005807, GREAT: Genomic Regions Enrichment of Annotations Tool)

SCR_003199https://scicrunch.org/resolver/SCR_003199 SciCrunch identifier (RRID:SCR_003199, GSEA software)

SCR_020130https://scicrunch.org/resolver/SCR_020130 SciCrunch identifier (RRID:SCR_020130, HiSeq 2000)

SCR_016386https://scicrunch.org/resolver/SCR_016386 SciCrunch identifier (RRID:SCR_016386, HiSeq 4000)

SCR_011867https://scicrunch.org/resolver/SCR_011867 SciCrunch identifier (RRID:SCR_011867, htseq-count)

SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)

SCR_016418https://scicrunch.org/resolver/SCR_016418 SciCrunch identifier (RRID:SCR_016418, pheatmap)

SCR_002105https://scicrunch.org/resolver/SCR_002105 SciCrunch identifier (RRID:SCR_002105, Samtools)

SCR_004463https://scicrunch.org/resolver/SCR_004463 SciCrunch identifier (RRID: SCR_004463, STAR)

SCR_015805https://scicrunch.org/resolver/SCR_015805 SciCrunch identifier (RRID:SCR_015805, StepOnePlus PCR System)

SCR_013035https://scicrunch.org/resolver/SCR_013035 SciCrunch identifier (RRID:SCR_013035, TopHat)

SCR_023156https://scicrunch.org/resolver/SCR_023156 SciCrunch identifier (RRID:SCR_023156, Trans-Blot Turbo transfer system)

mbexc.de...mming/https://mbexc.de/nfatc1-is-a-central-mediator-of-egfr-induced-arid1a-chromatin-dissociation-during-acinar-cell-reprogramming/ Website entry (mbexc.de)

Linked Antibodies

PID	Type	Antigen symbol	Antibody Registry ID	Name
primary-0100	primary	MAPK3/MAPK1	AB_330744	p44/42 MAPK (Erk1/2) Antibody
primary-0640	primary	H3K27ac	AB_2637079	H3K27ac polyclonal antibody
primary-1301	primary		AB_2722554	Rabbit negative Ctrl IgG
primary-1305	primary		AB_2722553	mouse IgG negative control antibody
primary-1554	primary	ACTB	AB_262011	Mouse Anti-Actin, β Monoclonal Antibody, Horseradish Peroxidase Conjugated
primary-1555	primary	AMY	AB_626668	Amylase
primary-1556	primary	ARID1A	AB_2637010	ARID1A/BAF250A Rabbit
primary-1557	primary	CDH1	AB_397581	Mouse Anti-Cadherin, E Monoclonal Antibody, Unconjugated
primary-1558	primary	CD45	AB_2174426	Leukocyte Common Antigen
primary-1559	primary	KRT19	AB_2281021	Cytokeratin 19
primary-1560	primary	EGFR	AB_10920395	EGFR
primary-1561	primary	p-EGFR (Y1068)	AB_732110	EGFR (phospho Y1068) antibody
primary-1562	primary	H3K27ac	AB_2885844	Histone H3K27ac (Acetyl Lys27) antibody
primary-1563	primary	HDAC1	AB_2295297	Anti-HDAC1
primary-1564	primary	H3	AB_331563	Histone H3 Antibody
primary-1565	primary	pMAPK (ErK1/2)	AB_331772	Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204)
primary-1566	primary	MIST1	AB_2798639	MIST1/bHLHa15 (D7N4B) XP®
primary-1567	primary	NFAT1	AB_448901	Anti-NFAT2 antibody
primary-1568	primary	NFATc1	AB_2152503	NFATc1
primary-1569	primary	NFATc1	AB_303308	Anti-NFAT2 antibody
secondary-1513	secondary		AB_330924	Anti-mouse IgG, HRP-linked Antibody

Technical Support: menoci@medizin.uni-goettingen.de

Department of Medical Informatics
University Medical Center Göttingen
Imprint

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External Resources

Linked Antibodies

Technical support

Links

Spokesperson

Prof. Dr. Tobias Moser

Spokesperson of Cluster of Excellence