| Property |
Value |
| Working Groups |
RG Cheng, 
RG Sakata |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2025.01.22.633148 |
| Publication Year |
2025 |
| Title |
Structures of the 26S proteasome in complex with the Hsp70 cochaperone Bag1 reveal a novel mechanism of ubiquitin-independent proteasomal degradation |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.1101/2025.01.22.633148 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Final article published in Science Advances here: doi:10.1126/sciadv.adz3026 |
| Authors |
Maestro-Lopez M, Cheung Cheng T, Muntaner J, Menendez M, Alonso M, Schweitzer A, Cuellar J, Valpuesta JM, Sakata E |
| First Author |
Maestro-Lopez M |
| Last Author |
Sakata E |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2025.01.22.633148v1.full.pdf Article fulltext
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
2/151204https://publications.goettingen-research-online.de/handle/2/151204 GRO.publications identifier
0000-0002-7955-9135https://orcid.org/0000-0002-7955-9135 ORCID identifier (Moisés Maestro-López)
0000-0003-2801-3084https://orcid.org/0000-0003-2801-3084 ORCID identifier (Tat Cheung Cheng)
0009-0004-8353-5007https://orcid.org/0009-0004-8353-5007 ORCID identifier (Jimena Muntaner Pérez-Urria)
0000-0002-3267-4443https://orcid.org/0000-0002-3267-4443 ORCID identifier (Margarita Menéndez)
0000-0002-7789-807Xhttps://orcid.org/0000-0002-7789-807X ORCID identifier (Jorge Cuéllar)
0000-0001-7468-8053https://orcid.org/0000-0001-7468-8053 ORCID identifier (José María Valpuesta)
0000-0002-8580-3683https://orcid.org/0000-0002-8580-3683 ORCID identifier (Eri Sakata)
PXD058407http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD058407 Pride proteome dataset (PXD058407)
1345https://prod.mbexc.uni-goettingen.de/literature/publications/1345 Published Data Registry entry (MBExC, final article)
7w3khttps://www.rcsb.org/structure/7w3k RCSB PDB Identifier (DOI:10.2210/pdb7w3k/pdb, reused)
1/572https://mbexc.uni-goettingen.de/archive/1/572 Research Data Archive (supplemental material)
0119pby33https://ror.org/0119pby33 ROR identifier (0119pby33, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
02gfc7t72https://ror.org/02gfc7t72 ROR identifier (02gfc7t72, Consejo Superior de Investigaciones Científicas)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_D615https://scicrunch.org/resolver/CVCL_D615 SciCrunch identifier (RRID:CVCL_D615, Expi293F)
CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)
SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)
SCR_018392https://scicrunch.org/resolver/SCR_018392 SciCrunch identifier (RRID:SCR_018392, crYOLO)
SCR_016501https://scicrunch.org/resolver/SCR_016501 SciCrunch identifier (RRID:SCR_016501, cryoSPARC)
SCR_016732https://scicrunch.org/resolver/SCR_016732 SciCrunch identifier (RRID:SCR_016732, CTFFIND)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_014956https://scicrunch.org/resolver/SCR_014956 SciCrunch identifier (RRID:SCR_014956, MeroX)
SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, Phenix)
SCR_014477https://scicrunch.org/resolver/SCR_014477 SciCrunch identifier (RRID:SCR_014477, Proteome Discoverer)
SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)
SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/01/24/2025.01.22.633148/DC1/embed/media-1.pdf?download=true Supplemental material
biopandas.github.io/biopandas/https://biopandas.github.io/biopandas/ Supplemental material (code, reused)
mbexc.de...ation/https://mbexc.de/structures-of-the-26s-proteasome-in-complex-with-the-hsp70-cochaperone-bag1-reveal-a-novel-mechanism-of-ubiquitin-independent-proteasomal-degradation/ Website entry (mbexc.de)