| Property |
Value |
| Working Groups |
RG Cheng, 
RG Sakata |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Unknown |
| PMID |
41719407 |
| DOI |
10.1126/sciadv.adz3026 |
| Publication Year |
2026 |
| Title |
Structures of the 26S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer |
| Journal |
Science Advances |
| ISSN |
2375-2548 |
| eISSN |
2375-2548 |
| URL |
https://doi.org/10.1126/sciadv.adz3026 |
| Issue |
8 |
| Volume |
12 |
| Journal Abbreviation |
Sci Adv |
| Authors |
Maestro-López M, Cheng TC, Muntaner J, Menéndez M, Alonso M, Schweitzer A, Ishizaka M, Tomko RJ, Cuéllar J, Valpuesta JM, Sakata E |
| First Author |
Maestro-López M |
| Last Author |
Sakata E |
External Resources
science....d=truehttps://www.science.org/doi/pdf/10.1126/sciadv.adz3026?download=true Article fulltext
EMD-52097https://www.ebi.ac.uk/pdbe/emdb/EMD-52097 EMBL-EBI EMDB identifier (EMD-52097)
EMD-52193https://www.ebi.ac.uk/pdbe/emdb/EMD-52193 EMBL-EBI EMDB identifier (EMD-52193)
EMD-52194https://www.ebi.ac.uk/pdbe/emdb/EMD-52194 EMBL-EBI EMDB identifier (EMD-52194)
EMD-53945https://www.ebi.ac.uk/pdbe/emdb/EMD-53945 EMBL-EBI EMDB identifier (EMD-53945)
EMD-52195https://www.ebi.ac.uk/pdbe/emdb/EMD-52195 EMBL-EBI EMDB identifier (EMD-52195)
EMD-52196https://www.ebi.ac.uk/pdbe/emdb/EMD-52196 EMBL-EBI EMDB identifier (EMD-52196)
2/163455https://publications.goettingen-research-online.de/handle/2/163455 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0002-7955-9135https://orcid.org/0000-0002-7955-9135 ORCID identifier (Moisés Maestro-López)
0000-0003-2801-3084https://orcid.org/0000-0003-2801-3084 ORCID identifier (Tat Cheung Cheng)
0009-0004-8353-5007https://orcid.org/0009-0004-8353-5007 ORCID identifier (Jimena Muntaner Pérez-Urria)
0000-0002-3267-4443https://orcid.org/0000-0002-3267-4443 ORCID identifier (Margarita Menéndez)
0000-0003-0906-5209https://orcid.org/0000-0003-0906-5209 ORCID identifier (Masato Ishizaka)
0000-0003-2515-1078https://orcid.org/0000-0003-2515-1078 ORCID identifier (Robert Tomko Jr.)
0000-0002-7789-807Xhttps://orcid.org/0000-0002-7789-807X ORCID identifier (Jorge Cuéllar)
0000-0001-7468-8053https://orcid.org/0000-0001-7468-8053 ORCID identifier (José María Valpuesta)
0000-0002-8580-3683https://orcid.org/0000-0002-8580-3683 ORCID identifier (Eri Sakata)
PXD058407http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD058407 Pride proteome dataset (PXD058407)
PXD069071http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD069071 Pride proteome dataset (PXD069071)
1154https://prod.mbexc.uni-goettingen.de/literature/publications/1154 Published Data Registry entry (MBExC, preprint)
9HEUhttps://www.rcsb.org/structure/9HEU RCSB PDB Identifier (DOI:10.2210/pdb9HEU/pdb)
9SZThttps://www.rcsb.org/structure/9SZT RCSB PDB Identifier (DOI:10.2210/pdb9SZT/pdb)
9SZVhttps://www.rcsb.org/structure/9SZV RCSB PDB Identifier (DOI:10.2210/pdb9SZV/pdb)
7W3Khttps://www.rcsb.org/structure/7W3K RCSB PDB Identifier (DOI:10.2210/pdb7w3k/pdb, reused)
0119pby33https://ror.org/0119pby33 ROR identifier (0119pby33, Centro de Investigación Biomédica en Red de Enfermedades Respiratorias)
05g3dte14https://ror.org/05g3dte14 ROR identifier (05g3dte14, Florida State University)
03xk60j79https://ror.org/03xk60j79 ROR identifier (03xk60j79, Institute of Physical Chemistry Blas Cabrera)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
015w4v032https://ror.org/015w4v032 ROR identifier (015w4v032, Spanish National Center for Biotechnology)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_D615https://scicrunch.org/resolver/CVCL_D615 SciCrunch identifier (RRID:CVCL_D615, Expi293F)
CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)
SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)
SCR_018392https://scicrunch.org/resolver/SCR_018392 SciCrunch identifier (RRID:SCR_018392, crYOLO)
SCR_016501https://scicrunch.org/resolver/SCR_016501 SciCrunch identifier (RRID:SCR_016501, cryoSPARC)
SCR_016732https://scicrunch.org/resolver/SCR_016732 SciCrunch identifier (RRID:SCR_016732, CTFFIND)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_014956https://scicrunch.org/resolver/SCR_014956 SciCrunch identifier (RRID:SCR_014956, MeroX)
SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, Phenix)
SCR_014477https://scicrunch.org/resolver/SCR_014477 SciCrunch identifier (RRID:SCR_014477, Proteome Discoverer)
SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)
SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)
science....sm.pdfhttps://www.science.org/doi/suppl/10.1126/sciadv.adz3026/suppl_file/sciadv.adz3026_sm.pdf Supplemental material
science....s6.ziphttps://www.science.org/doi/suppl/10.1126/sciadv.adz3026/suppl_file/sciadv.adz3026_movies_s1_to_s6.zip Supplemental material (video)
mbexc.de...ation/https://mbexc.de/structures-of-the-26s-proteasome-in-complex-with-the-hsp70-cochaperone-bag1-reveal-a-novel-mechanism-of-ubiquitin-independent-proteasomal-degradation/ Website entry (mbexc.de)
10.5281/zenodo.17424376https://doi.org/10.5281/zenodo.17424376 Zenodo identifier (10.5281/zenodo.17424376)