| Property |
Value |
| Working Groups |
RG Stadelmann-Nessler, 
RG Thomas |
| Subproject |
RA2.2 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
33257876 |
| DOI |
10.1038/s41593-020-00758-5 |
| Publication Year |
2020 |
| Title |
Olfactory transmucosal SARS-CoV-2 invasion as a port of central nervous system entry in individuals with COVID-19 |
| Journal |
Nature Neuroscience |
| ISSN |
1097-6256 |
| eISSN |
1546-1726 |
| URL |
http://dx.doi.org/10.1038/s41593-020-00758-5 |
| Journal Abbreviation |
Nat Neurosci |
| Extra |
TRR 274 |
| Authors |
Meinhardt J, Radke J, Dittmayer C, Franz J, Thomas C, Mothes R, Laue M, Schneider J, Brünink S, Greuel S, Lehmann M, Hassan O, Aschman T, Schumann E, Chua RL, Conrad C, Eils R, Stenzel W, Windgassen M, Rößler L, Goebel H, Gelderblom HR, Martin H, Nitsche A, Schulz-Schaeffer WJ, Hakroush S, Winkler MS, Tampe B, Scheibe F, Körtvélyessy P, Reinhold D, Siegmund B, Kühl AA, Elezkurtaj S, Horst D, Oesterhelweg L, Tsokos M, Ingold-Heppner B, Stadelmann C, Drosten C, Corman VM, Radbruch H, Heppner FL |
| First Author |
Meinhardt J |
| Last Author |
Heppner FL |
External Resources
nature.c...-5.pdfhttps://www.nature.com/articles/s41593-020-00758-5.pdf Article fulltext
2/82152http://resolver.sub.uni-goettingen.de/purl?2/82152 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0001-9860-2007https://orcid.org/0000-0001-9860-2007 ORCID identifier (Josefine Radke)
0000-0001-7523-6622https://orcid.org/0000-0001-7523-6622 ORCID identifier (Jonas Franz)
0000-0002-7386-1181https://orcid.org/0000-0002-7386-1181 ORCID identifier (Carolina Thomas)
0000-0002-0494-1022https://orcid.org/0000-0002-0494-1022 ORCID identifier (Julia Schneider)
0000-0001-5945-9957https://orcid.org/0000-0001-5945-9957 ORCID identifier (Robert Lorenz Chua)
0000-0002-0034-4036https://orcid.org/0000-0002-0034-4036 ORCID identifier (Roland Eils)
0000-0002-4357-9863https://orcid.org/0000-0002-4357-9863 ORCID identifier (Björn Tampe)
0000-0002-8773-6090https://orcid.org/0000-0002-8773-6090 ORCID identifier (Franziska Scheibe)
0000-0002-0055-958Xhttps://orcid.org/0000-0002-0055-958X ORCID identifier (Britta Siegmund)
0000-0003-1766-5458https://orcid.org/0000-0003-1766-5458 ORCID identifier (Christine Stadelmann-Nessler)
0000-0001-7923-0519https://orcid.org/0000-0001-7923-0519 ORCID identifier (Christian Drosten)
0000-0002-3605-0136https://orcid.org/0000-0002-3605-0136 ORCID identifier (Victor Max Corman)
0000-0001-9816-8917https://orcid.org/0000-0001-9816-8917 ORCID identifier (Frank L. Heppner)
10https://rdp.sfb274.de/literature/publications/10 Published Data Registry entry (TRR274)
1/174https://mbexc.uni-goettingen.de/archive/1/174 Research Data Archive (supplemental material)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
04a7f6w43https://ror.org/04a7f6w43 ROR identifier (04a7f6w43, Max Planck Institute of Experimental Medicine)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
01y9bpm73https://ror.org/01y9bpm73 ROR identifier (01y9bpm73, University of Göttingen)
01hcx6992https://ror.org/01hcx6992 ROR identifier (01hcx6992, Humboldt-Universität zu Berlin)
0493xsw21https://ror.org/0493xsw21 ROR identifier (0493xsw21, Berlin Institute of Health at Charité - Universitätsmedizin Berlin)
046ak2485https://ror.org/046ak2485 ROR identifier (046ak2485, Freie Universität Berlin)
01k5qnb77https://ror.org/01k5qnb77 ROR identifier (01k5qnb77, Robert Koch Institute)
04rcqnp59https://ror.org/04rcqnp59 ROR identifier (04rcqnp59, Heidelberg University)
01jdpyv68https://ror.org/01jdpyv68 ROR identifier (01jdpyv68, Saarland University)
00ggpsq73https://ror.org/00ggpsq73 ROR identifier (00ggpsq73, Otto-von-Guericke University Magdeburg)
02pqn3g31https://ror.org/02pqn3g31 ROR identifier (02pqn3g31, Deutschen Konsortium für Translationale Krebsforschung)
03dbpxy52https://ror.org/03dbpxy52 ROR identifier (03dbpxy52, DRK Kliniken Berlin)
SCR_014199https://scicrunch.org/resolver/SCR_014199 SciCrunch identifier (RRID:SCR_014199, Adobe Photoshop)
SCR_018361https://scicrunch.org/resolver/SCR_018361 SciCrunch identifier (RRID:SCR_018361, Biorender)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_002636https://scicrunch.org/resolver/SCR_002636 SciCrunch identifier (RRID:SCR_002636, OME-TIFF Format)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41593-020-00758-5/MediaObjects/41593_2020_758_MOESM1_ESM.pdf Supplemental material
nanotomy...x.htmlhttp://www.nanotomy.org/OA/Meinhardt2020NNS/index.html Supplemental material (figure)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41593-020-00758-5/MediaObjects/41593_2020_758_MOESM2_ESM.pdf Supplemental material (reporting summary)
mbexc.de...ients/https://mbexc.de/olfactory-transmucosal-sars-cov-2-invasion-as-port-of-central-nervous-system-entry-in-covid-19-patients/ Website entry (mbexc.de)
Q103806429https://www.wikidata.org/wiki/Q103806429 Wikidata ID
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0025 |
|
primary |
SARS |
AB_2891144 |
Anti-SARS spike glycoprotein antibody [3A2] - Coronavirus |
| primary-0028 |
|
primary |
Olig2 |
AB_494617 |
Anti-Human Olig2 Rabbit IgG |
| primary-0076 |
|
primary |
S100 |
AB_10013383 |
S100 antibody |
| primary-0077 |
|
primary |
KRT |
AB_2132885 |
Pan-Keratin antibody |
| primary-0078 |
|
primary |
S100A9 |
AB_1007174 |
S100A9 mouse monoclonal antibody |
| primary-0079 |
|
primary |
CD56 |
AB_321501 |
CD56 antibody |
| primary-0080 |
|
primary |
OMP |
AB_664696 |
Anti-Olfactory Marker Protein Antibody |
| primary-0081 |
|
primary |
TUBB3 |
|
Recombinant Anti-beta III Tubulin antibody |
| primary-0082 |
|
primary |
NEFH |
AB_477272 |
Anti-Neurofilament 200 antibody |
| primary-0083 |
|
primary |
ACE2 |
AB_10732845 |
ACE2 antibody |
| secondary-0084 |
|
secondary |
|
AB_2338569 |
Biotin-SP (long spacer) AffiniPure Goat Anti-Mouse IgG (H+L) |