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Publication

Property	Value
Working Groups	RG Fernandez-Busnadiego
Subproject	None
Open Access	Yes
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	38759629
DOI	10.1016/j.molcel.2024.04.018
Publication Year	2024
Title	Autophagy preferentially degrades non-fibrillar polyQ aggregates
Journal	Molecular Cell
ISSN	1097-2765
URL	http://dx.doi.org/10.1016/j.molcel.2024.04.018
Pages	1980-1994.e8
Issue	10
Volume	84
Journal Abbreviation	Mol Cell
Authors	Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling F
First Author	Zhao DY
Last Author	Wilfling F

External Resources

scienced...in.pdfhttps://www.sciencedirect.com/science/article/pii/S1097276524003836/pdfft?md5=364da021e20b996748ae2a6ba601a157&pid=1-s2.0-S1097276524003836-main.pdf Article fulltext

40827https://www.addgene.org/40827 Addgene identifier (40827, reused)

45147https://scicrunch.org/resolver/45147 Addgene identifier (45147, reused)

48138https://www.addgene.org/48138 Addgene identifier (48138, reused)

84573https://www.addgene.org/84573 Addgene identifier (84573, reused)

98750https://www.addgene.org/98750 Addgene identifier (98750, reused)

175025https://www.addgene.org/175025 Addgene identifier (175025, reused)

10.17632/k66ygh2hy8.1https://doi.org/10.17632/k66ygh2hy8.1 DOI (10.17632/k66ygh2hy8.1, Mendeley dataset)

EMD-18110https://www.ebi.ac.uk/pdbe/emdb/EMD-18110 EMBL-EBI EMDB identifier (EMD-18110)

EMD-18114https://www.ebi.ac.uk/pdbe/emdb/EMD-18114 EMBL-EBI EMDB identifier (EMD-18114)

EMD-18115https://www.ebi.ac.uk/pdbe/emdb/EMD-18115 EMBL-EBI EMDB identifier (EMD-18115)

EMD-18116https://www.ebi.ac.uk/pdbe/emdb/EMD-18116 EMBL-EBI EMDB identifier (EMD-18116)

EMD-18117https://www.ebi.ac.uk/pdbe/emdb/EMD-18117 EMBL-EBI EMDB identifier (EMD-18117)

EMD-18118https://www.ebi.ac.uk/pdbe/emdb/EMD-18118 EMBL-EBI EMDB identifier (EMD-18118)

9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)

0000-0002-8889-7371https://orcid.org/0000-0002-8889-7371 ORCID identifier (Felix J. B. Bäuerlein)

0000-0002-0289-4082https://orcid.org/0000-0002-0289-4082 ORCID identifier (Itika Saha)

0000-0002-7941-135Xhttps://orcid.org/0000-0002-7941-135X ORCID identifier (F. Ulrich Hartl)

0000-0001-8154-8809https://orcid.org/0000-0001-8154-8809 ORCID identifier (Wolfgang Baumeister)

0000-0002-6559-7261https://orcid.org/0000-0002-6559-7261 ORCID identifier (Florian Wilfling)

PXD04426http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD04426 Pride proteome dataset (PXD04426)

1/516https://mbexc.uni-goettingen.de/archive/1/516 Research Data Archive (supplemental material)

03zj4c476https://ror.org/03zj4c476 ROR identifier (03zj4c476, Aligning Science Across Parkinson's)

02panr271https://ror.org/02panr271 ROR identifier (02panr271, Max Planck Institute of Biophysics)

04py35477https://ror.org/04py35477 ROR identifier (04py35477, Max Planck Institute of Biochemistry)

05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)

AB_258167https://scicrunch.org/resolver/AB_258167 SciCrunch identifier (RRID:AB_258167)

AB_258434https://scicrunch.org/resolver/AB_258434 SciCrunch identifier (RRID:AB_258434)

AB_298039https://scicrunch.org/resolver/AB_298039 SciCrunch identifier (RRID:AB_298039)

AB_309938https://scicrunch.org/resolver/AB_309938 SciCrunch identifier (RRID:AB_309938)

AB_390913https://scicrunch.org/resolver/AB_390913 SciCrunch identifier (RRID:AB_390913)

AB_477583https://scicrunch.org/resolver/AB_477583 SciCrunch identifier (RRID:AB_477583)

AB_627695https://scicrunch.org/resolver/AB_627695 SciCrunch identifier (RRID:AB_627695)

AB_628423https://scicrunch.org/resolver/AB_628423 SciCrunch identifier (RRID:AB_628423)

AB_796155https://scicrunch.org/resolver/AB_796155 SciCrunch identifier (RRID:AB_796155)

AB_2196009https://scicrunch.org/resolver/AB_2196009 SciCrunch identifier (RRID:AB_2196009)

AB_2535849https://scicrunch.org/resolver/AB_2535849 SciCrunch identifier (RRID:AB_2535849)

AB_2920696https://scicrunch.org/resolver/AB_2920696 SciCrunch identifier (RRID:AB_2920696)

AB_3095587https://scicrunch.org/resolver/AB_3095587 SciCrunch identifier (RRID:AB_3095587)

AB_10003146https://scicrunch.org/resolver/AB_10003146 SciCrunch identifier (RRID:AB_10003146)

AB_10664137https://scicrunch.org/resolver/AB_10664137 SciCrunch identifier (RRID:AB_10664137)

AB_11150489https://scicrunch.org/resolver/AB_11150489 SciCrunch identifier (RRID:AB_11150489)

CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)

CVCL_D3YThttps://scicrunch.org/resolver/CVCL_D3YT SciCrunch identifier (RRID:CVCL_D3YT, Neuro2a-tNhtt-EGFP-150Q)

CVCL_D3YShttps://scicrunch.org/resolver/CVCL_D3YS SciCrunch identifier (RRID:CVCL_D3YS, Neuro2a-tNhtt-EGFP-60Q)

SCR_010279https://scicrunch.org/resolver/SCR_010279 SciCrunch identifier (RRID:SCR_010279, Adobe Illustrator)

SCR_007353https://scicrunch.org/resolver/SCR_007353 SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)

SCR_013955https://scicrunch.org/resolver/SCR_013955 SciCrunch identifier (RRID:SCR_013955, Benchling)

SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)

SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

SCR_014237https://scicrunch.org/resolver/SCR_014237 SciCrunch identifier (RRID:SCR_014237, Huygens)

SCR_003297https://scicrunch.org/resolver/SCR_003297 SciCrunch identifier (RRID:SCR_003297, IMOD)

SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)

SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)

SCR_016499https://scicrunch.org/resolver/SCR_016499 SciCrunch identifier (RRID:SCR_016499, MotionCor2)

SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)

SCR_008394https://scicrunch.org/resolver/SCR_008394 SciCrunch identifier (RRID:SCR_008394, Python)

SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)

SCR_003220https://scicrunch.org/resolver/SCR_003220 SciCrunch identifier (RRID:SCR_003220, Template-O-Matic Toolbox)

SCR_013672https://scicrunch.org/resolver/SCR_013672 SciCrunch identifier (RRID:SCR_013672, ZEN Digital Imaging for Light Microscopy)

SCR_024857https://scicrunch.org/resolver/SCR_024857 SciCrunch identifier (RRID:SCR_024857, Leica DM6 B Upright Microscope)

ars.els-...c1.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S1097276524003836-mmc1.pdf Supplemental material

github.c...orithmhttps://github.com/FJBauerlein/LisC_Algorithm Supplemental material (code, reused)

github.com/williamnwan/TOMOMANhttps://github.com/williamnwan/TOMOMAN Supplemental material (code, reused)

Linked Antibodies

PID	Type	Antigen symbol	Antibody Registry ID	Name
primary-0111	primary	TUBA4A	AB_477583	Anti-α-Tubulin antibody
primary-0193	primary	VCP	AB_298039	Anti-VCP antibody
primary-0344	primary	GFP	AB_627695	Anti-GFP Antibody
primary-0784	primary	GFP	AB_390913	Anti-GFP antibody
primary-0990	primary	UBB	AB_628423	Anti-Ubiquitin Antibody (P4D1)
primary-0997	primary	MAP1LC3B	AB_796155	Anti-LC3B antibody
primary-1727	primary	Myc Tag	AB_309938	Anti-Myc Tag Antibody, clone 4A6
primary-1728	primary	p62	AB_2196009	p62 (human) polyclonal antibody
primary-1729	primary	ATN1	AB_2920696	Anti-polyQ specific Antibody, clone MW1
primary-1731	primary	MAP1LC3B	AB_10003146	LC3B Antibody - BSA Free
primary-1732	primary		AB_10664137	Beta-Actin Antibody
primary-1733	primary	MAP1LC3B	AB_11150489	LC3B Antikörper (G-9)
secondary-0019	secondary		AB_2535849	Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555
secondary-0376	secondary		AB_258434	Anti-Rabbit IgG (whole molecule)–Peroxidase antibody
secondary-1003	secondary		AB_258167	Anti-Mouse IgG (whole molecule)–Peroxidase antibody
secondary-1730	secondary		AB_3095587	Anti-Mouse IgG (H+L), F(ab′)2 fragment, CF™350 antibody produced in goat

Technical Support: menoci@medizin.uni-goettingen.de

Department of Medical Informatics
University Medical Center Göttingen
Imprint

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External Resources

Linked Antibodies

Technical support

Links

Spokesperson

Prof. Dr. Tobias Moser

Spokesperson of Cluster of Excellence