Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0997 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0997 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | MAP1LC3B |
| Antibody Registry ID(s) | AB_796155 |
| Name | Anti-LC3B antibody |
| Alternative name | ATG8F |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | rat, human, mouse |
| Clone | |
| Isotype | |
| Clonality | polyclonal |
| Demasking | unknown |
| Antigen | synthetic peptide corresponding to amino acids 2-15 of human LC3B, conjugated to KLH via a C-terminal cysteine residue |
| Crafted By | company |
| Company / Manufacturer | Sigma-Aldrich |
| Catalog no. | L7543 |
| Lot no. | |
| Description | indirect immunofluorescence: 5-10 μg/mL using human HeLa cells western blot: 1-2 μg/mL using whole extracts of rat and mouse brain |
| Localization | |
| Storage instruction | storage temp. −20°C |
| Receipt date | 2022-01-01 00:00:00 |
| Preparation date | 2022-03-18 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
Applications
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Linked publications
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS
Nat Commun 2023 : 10.1038/s41467-023-36058-2
RNA helicase IGHMBP2 regulates THO complex to ensure cellular mRNA homeostasis
Prusty AB, Hirmer A, Sierra-Delgado JA, Huber H, Guenther U, Schlosser A, Dybkov O, Yildirim E, Urlaub H, Meyer KC, Jablonka S, Erhard F, Fischer U
Cell Rep 2024 : 10.1016/j.celrep.2024.113802
Autophagy preferentially degrades non-fibrillar polyQ aggregates
Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling F
Mol Cell 2024 : 10.1016/j.molcel.2024.04.018
