View publication

↩ Back to all publications
Publication
PropertyValue
Working Groups RG Fernandez-Busnadiego
SubprojectRA2.1
Open AccessOpen Access Yes
Publication TypePreprint
Peer ReviewedNo
DOIDOI 10.1101/2022.02.18.481043
Publication Year2022
TitleThe AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
JournalbioRxiv
ISSNno ISSN (NLM ID:101680187)
URL http://dx.doi.org/10.1101/2022.02.18.481043
Journal AbbreviationbioRxiv
ExtraFinal article published in Nature Communications here: doi:10.1038/s41467-023-36058-2
AuthorsSaha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
First AuthorSaha I
Last AuthorHipp MS

 External Resources

 12259  Addgene identifier (12259, reused)

 12260  Addgene identifier (12260, reused)

 23971  Addgene identifier (23971, reused)

 23972  Addgene identifier (23972, reused)

 23973  Addgene identifier (23973, reused)

 23974  Addgene identifier (23974, reused)

 100521  Addgene identifier (100521, reused)

 biorxiv....ll.pdf  Article fulltext

 gro-2/106453  GRO.publications identifier

 0000-0002-0289-4082  ORCID identifier (Itika Saha)

 0000-0002-1056-3849  ORCID identifier (Patricia Yuste Checa)

 0000-0003-3520-5439  ORCID identifier (Qiang Guo)

 0000-0002-2050-413X  ORCID identifier (Hauke Holthusen)

 0000-0001-8964-6120  ORCID identifier (Victoria Anne Trinkaus)

 0000-0003-1052-8485  ORCID identifier (Irina Dudanova)

 0000-0002-8366-7622  ORCID identifier (Ruben Fernandez-Busnadiego)

 0000-0002-7941-135X  ORCID identifier (F. Ulrich Hartl)

 0000-0002-0497-3016  ORCID identifier (Mark S. Hipp)

 654  Published Data Registry entry (MBExC, final article)

 1/300  Research Data Archive (supplemental material)

 05xy1nn52  ROR identifier (05xy1nn52, Multiscale Bioimaging)

 021ft0n22  ROR identifier (021ft0n22, University Medical Center Göttingen)

 01y9bpm73  ROR identifier (01y9bpm73, University of Göttingen)

 SCR_007353  SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)

 SCR_002285  SciCrunch identifier (RRID:SCR_002285, Fiji)

 SCR_008520  SciCrunch identifier (RRID:SCR_008520, FlowJo)

 SCR_002798  SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

 SCR_003070  SciCrunch identifier (RRID:SCR_003070, ImageJ)

 SCR_003297  SciCrunch identifier (RRID:SCR_003297, IMOD)

 SCR_014485  SciCrunch identifier (RRID:SCR_014485, MaxQuant)

 SCR_016499  SciCrunch identifier (RRID:SCR_016499, MotionCor 2)

 SCR_015753  SciCrunch identifier (RRID:SCR_015753, Perseus)

 SCR_017293  SciCrunch identifier (RRID:SCR_017293, SerialEM)

 SCR_013672  SciCrunch identifier (RRID:SCR_013672, ZEN Digital Imaging for Light Microscopy)

 biorxiv....d=true  Supplemental material

 mbexc.de...seeds/  Website entry (mbexc.de)

Linked Antibodies

PIDAGTypeAntigen symbolAntibody Registry IDName
primary-0008primaryGAPDHAB_2107445Anti-Glyceraldehyde-3-Phosphate Dehydrogenase Antibody
primary-0111primaryTUBA4AAB_477583Anti-α-Tubulin antibody
primary-0185primaryMAPTAB_223647Phospho-Tau (Ser202, Thr205) Monoclonal Antibody
primary-0190primaryUBBAB_1587578Anti-Ubiquitin Antibody
primary-0193primaryVCPAB_298039Anti-VCP antibody
primary-0619primaryATG7 AB_10831194Atg7 (D12B11) antibody
primary-0784primaryGFPAB_390913Anti-GFP antibody
primary-0988primaryVCPAB_2304347p97/VCP Antibody
primary-0989primaryUBB AB_2895239Recombinant Anti-Ubiquitin (linkage-specific K63) antibody [EPR8590-448]
primary-0990primaryUBBAB_628423Anti-Ubiquitin Antibody (P4D1)
primary-0991primaryMAPT AB_11167058Tau (phospho Ser356) antibody
primary-0992primaryNPLOC4 AB_1854586Anti-NPLOC4 antibody
primary-0993primaryUFD1 AB_10678868Anti-UFD1L antibody
primary-0994primaryUbiquitinylated proteinsAB_612093Anti-Ubiquitinylated proteins Antibody
primary-0995primaryMAPT AB_10980631Tau Monoclonal Antibody
primary-0996primaryMAPT AB_2341273Anti-Human Tau/Repeat Domain (2B11) Mouse IgG MoAb
primary-0997primaryMAP1LC3B AB_796155Anti-LC3B antibody
primary-0998primaryATG5 AB_2062340Atg5 Antibody
primary-0999primaryPSMD11AB_2268979PSMD11 Polyclonal antibody
secondary-0042secondaryAB_2534033Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Cyanine5
secondary-0376secondaryAB_258434Anti-Rabbit IgG (whole molecule)–Peroxidase antibody
secondary-1000secondaryAB_2534032Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Cyanine5
secondary-1001secondaryAB_2340863 Alexa Fluor® 647 AffiniPure Donkey Anti-Mouse IgG (H+L)
secondary-1002secondaryAB_2556746Donkey anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, DyLight 488
secondary-1003secondaryAB_258167Anti-Mouse IgG (whole molecule)–Peroxidase antibody
secondary-1004secondaryAB_10956588IRDye® 680RD Goat anti-Mouse IgG Secondary Antibody
secondary-1005secondaryAB_621843IRDye® 800CW Goat anti-Rabbit IgG Secondary Antibody