| Property |
Value |
| Working Groups |
RG Fischer, 
RG Outeiro |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2024.09.12.612649 |
| Publication Year |
2024 |
| Title |
The epitranscriptomic m6A RNA modification modulates synaptic function in ageing and in a mouse model of synucleinopathy |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.1101/2024.09.12.612649 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Final article published in npj Parkinsons Disease here: doi:10.1038/s41531-026-01362-3 |
| Authors |
Chopra A, Xylaki M, Yin F, Castro-Hernández R, Merghani M, Grande V, Mollenhauer B, Fischer A, Outeiro TF |
| First Author |
Chopra A |
| Last Author |
Outeiro TF |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2024.09.12.612649v2.full.pdf Article fulltext
2/149990http://resolver.sub.uni-goettingen.de/purl?2/149990 GRO.publications identifier
0000-0003-2250-3787https://orcid.org/0000-0003-2250-3787 ORCID identifier (Avika Chopra)
0000-0002-7892-8621https://orcid.org/0000-0002-7892-8621 ORCID identifier (Mary Xylaki)
0009-0009-6114-2145https://orcid.org/0009-0009-6114-2145 ORCID identifier (Madiha Merghani)
0000-0001-8437-3645https://orcid.org/0000-0001-8437-3645 ORCID identifier (Brit Mollenhauer)
0000-0001-8546-1161https://orcid.org/0000-0001-8546-1161 ORCID identifier (André Fischer)
0000-0003-1679-1727https://orcid.org/0000-0003-1679-1727 ORCID identifier (Tiago Fleming Outeiro)
384https://sfb1286.uni-goettingen.de/literature/publications/384 Published Data Registry entry (CRC 1286)
1381https://prod.mbexc.uni-goettingen.de/literature/publications/1381 Published Data Registry entry (MBExC, final article)
1/722https://mbexc.uni-goettingen.de/archive/1/722 Research Data Archive (supplemental material)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
01kj2bm70https://ror.org/01kj2bm70 ROR identifier (01kj2bm70, Newcastle University)
0270sxy44https://ror.org/0270sxy44 ROR identifier (0270sxy44, Paracelsus Elena Klinik Kassel)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
IMSR_JAX:008239https://scicrunch.org/resolver/IMSR_JAX:008239 SciCrunch identifier (RRID:IMSR_JAX:008239, C57BL/6J-Gtpbp2nmf205/J)
SCR_007358https://scicrunch.org/resolver/SCR_007358 SciCrunch identifier (RRID:SCR_007358, CellProfiler)
SCR_005748https://scicrunch.org/resolver/SCR_005748 SciCrunch identifier (RRID:SCR_005748, ClueGO)
SCR_003032https://scicrunch.org/resolver/SCR_003032 SciCrunch identifier (RRID:SCR_003032, Cytoscape)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_018419https://scicrunch.org/resolver/SCR_018419 SciCrunch identifier (RRID:SCR_018419, GeneOverlap)
SCR_014601https://scicrunch.org/resolver/SCR_014601 SciCrunch identifier (RRID:SCR_014601, ggplot2)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_002924https://scicrunch.org/resolver/SCR_002924 SciCrunch identifier (RRID:SCR_002924, HomoloGene)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_007370https://scicrunch.org/resolver/SCR_007370 SciCrunch identifier (RRID:SCR_007370, Imaris)
SCR_012773https://scicrunch.org/resolver/SCR_012773 SciCrunch identifier (RRID:SCR_012773, KEGG)
SCR_001905https://scicrunch.org/resolver/SCR_001905 SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)
SCR_017330https://scicrunch.org/resolver/SCR_017330 SciCrunch identifier (RRID:SCR_017330, SynGo)
SCR_022263https://scicrunch.org/resolver/SCR_022263 SciCrunch identifier (RRID:SCR_022263, Zeiss LSM 900 with Airyscan 2)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/11/02/2024.09.12.612649/DC1/embed/media-1.jpg?download=true Supplemental material (figure)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2024/11/02/2024.09.12.612649/DC2/embed/media-2.jpg?download=true Supplemental material (figure)
mbexc.de...pathy/https://mbexc.de/the-epitranscriptomic-m6a-rna-modification-modulates-synaptic-function-in-ageing-and-in-a-mouse-model-of-synucleinopathy/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0329 |
 |
primary |
SYT1 |
AB_993036 |
Anti-Synaptotagmin 1 antibody |
| primary-0946 |
|
primary |
MAP2 |
AB_2137880 |
MAP2 Polyclonal antibody |
| primary-1916 |
|
primary |
FTO |
AB_10565042 |
Anti-FTO antibody [5-2H10] |
| primary-1917 |
|
primary |
METTL14 |
AB_2799383 |
METTL14 (D8K8W) Rabbit mAb |
| primary-1918 |
|
primary |
YTHDF1 |
AB_2217473 |
YTHDF1 Polyklonaler Antikörper |
| primary-1919 |
|
primary |
PSD95 |
AB_10804286 |
PSD95 antibody PDZ domain |
| primary-1920 |
|
primary |
PSD95 |
AB_1264242 |
PSD95 (D74D3) XP® Rabbit mAb |
| primary-1921 |
|
primary |
SYT1 |
AB_887835 |
Synaptotagmin1 antibody luminal domain |