| Property |
Value |
| Working Groups |
RG Griesinger |
| Subproject |
RA2.2 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
35500536 |
| DOI |
10.1016/j.ebiom.2022.104021 |
| Publication Year |
2022 |
| Title |
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial |
| Journal |
eBioMedicine |
| ISSN |
2352-3964 |
| eISSN |
2352-3964 |
| URL |
http://dx.doi.org/10.1016/j.ebiom.2022.104021 |
| Pages |
104021 |
| Volume |
80 |
| Journal Abbreviation |
eBioMedicine |
| Authors |
Levin J, Sing N, Melbourne S, Morgan A, Mariner C, Spillantini MG, Wegrzynowicz M, Dalley JW, Langer S, Ryazanov S, Leonov A, Griesinger C, Schmidt F, Weckbecker D, Prager K, Matthias T, Giese A |
| First Author |
Levin J |
| Last Author |
Giese A |
External Resources
thelance...0205-5https://www.thelancet.com/action/showPdf?pii=S2352-3964%2822%2900205-5 Article fulltext
2/108672https://publications.goettingen-research-online.de/handle/2/108672 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0002-1266-4344https://orcid.org/0000-0002-1266-4344 ORCID identifier (Christian Griesinger)
1/56https://mbexc.uni-goettingen.de/archive/1/56 Research Data Archive (supplemental material)
055vbxf86https://ror.org/055vbxf86 ROR identifier (055vbxf86, Addenbrooke's Hospital)
05591te55https://ror.org/05591te55 ROR identifier (05591te55, Ludwig-Maximilians-Universität München)
03e76ya46https://ror.org/03e76ya46 ROR identifier (03e76ya46, Max Planck Institute for Biophysical Chemistry)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
025z3z560https://ror.org/025z3z560 ROR identifier (025z3z560, Munich Cluster for Systems Neurology)
01dr6c206https://ror.org/01dr6c206 ROR identifier (01dr6c206, Polish Academy of Sciences)
013meh722https://ror.org/013meh722 ROR identifier (013meh722, University of Cambridge)
SCR_003751https://scicrunch.org/resolver/SCR_003751 SciCrunch identifier (RRID:SCR_003751, Medical Dictionary for Regulatory Activities )
SCR_008567https://scicrunch.org/resolver/SCR_008567 SciCrunch identifier (RRID:SCR_008567, Statistical Analysis System)
thelance...1.docxhttps://www.thelancet.com/cms/10.1016/j.ebiom.2022.104021/attachment/3c284e1c-42d4-48a4-a699-a5b9ecb71e61/mmc1.docx Supplemental material
thelance...2.pptxhttps://www.thelancet.com/cms/10.1016/j.ebiom.2022.104021/attachment/fd794208-15f5-4e56-9b56-a98a94e523a2/mmc2.pptx Supplemental material
mbexc.de...ebo-c/https://mbexc.de/safety-tolerability-and-pharmacokinetics-of-the-oligomer-modulator-anle138b-with-exposure-levels-sufficient-for-therapeutic-efficacy-in-a-murine-parkinson-model-a-randomised-double-blind-placebo-c/ Website entry (mbexc.de)