| Property | Value |
|---|
| Working Groups |  RG Griesinger |
| Subproject | None |
| Open Access |  Yes |
| Publication Type | Preprint |
| Peer Reviewed | No |
| DOI |  10.1101/2025.03.11.642540 |
| Publication Year | 2025 |
| Title | Anle138b ameliorates pathological phenotypes in mouse and cellular models of Huntington’s disease |
| Journal | bioRxiv |
| ISSN | no ISSN (NLM ID:101680187) |
| URL | https://doi.org/10.1101/2025.03.11.642540 |
| Journal Abbreviation | bioRxiv |
| Extra | Not yet finally published in a peer-reviewed journal |
| Authors | da Silva Padilha M, Koyuncu S, Chabanis E, Ryazanov S, Leonov A, Vilchez D, Klein R, Giese A, Griesinger C, Dudanova I |
| First Author | da Silva Padilha M |
| Last Author | Dudanova I |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2025.03.11.642540v1.full.pdf
Article fulltext
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090
NCBI taxonomy (mouse, Mus musculus)
0000-0001-8141-7163https://orcid.org/0000-0001-8141-7163
ORCID identifier (Miguel da Silva Padilha)
0000-0001-7937-3974https://orcid.org/0000-0001-7937-3974
ORCID identifier (Seda Koyuncu)
0009-0002-2924-7085https://orcid.org/0009-0002-2924-7085
ORCID identifier (Evangeline Chabanis)
0000-0002-2685-7956https://orcid.org/0000-0002-2685-7956
ORCID identifier (Sergey Ryazanov)
0000-0002-5586-9382https://orcid.org/0000-0002-5586-9382
ORCID identifier (Andrei Leonov)
0000-0002-0801-0743https://orcid.org/0000-0002-0801-0743
ORCID identifier (David Vilchez)
0000-0002-3109-0163https://orcid.org/0000-0002-3109-0163
ORCID identifier (Rüdiger Klein)
0000-0002-8238-4102https://orcid.org/0000-0002-8238-4102
ORCID identifier (Armin Giese)
0000-0002-1266-4344https://orcid.org/0000-0002-1266-4344
ORCID identifier (Christian Griesinger)
0000-0003-1052-8485https://orcid.org/0000-0003-1052-8485
ORCID identifier (Irina Dudanova)
04c4bwh63https://ror.org/04c4bwh63
ROR identifier (04c4bwh63, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases)
03g267s60https://ror.org/03g267s60
ROR identifier (03g267s60, Max Planck Institute for Biological Intelligence)
03av75f26https://ror.org/03av75f26
ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
05xy1nn52https://ror.org/05xy1nn52
ROR identifier (05xy1nn52, Multiscale Bioimaging)
05mxhda18https://ror.org/05mxhda18
ROR identifier (05mxhda18, University Hospital Cologne)
IMSR_JAX:002810https://scicrunch.org/resolver/IMSR_JAX:002810
SciCrunch identifier (RRID:IMSR_JAX:002810, B6CBA-Tg(HDexon1)62Gpb/1J)
IMSR_JAX:029928https://scicrunch.org/resolver/IMSR_JAX:029928
SciCrunch identifier (RRID:IMSR_JAX:029928, B6.129S1-Htttm1.1Mfc/190ChdiJ)
SCR_002285https://scicrunch.org/resolver/SCR_002285
SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798
SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_003070https://scicrunch.org/resolver/SCR_003070
SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_024663https://scicrunch.org/resolver/SCR_024663
SciCrunch identifier (RRID:SCR_024663, Leica STELLARIS 5 microscope)
SCR_023794https://scicrunch.org/resolver/SCR_023794
SciCrunch identifier (RRID:SCR_023794, Leica Thunder Imager Live Cell system)
mbexc.de...sease/https://mbexc.de/anle138b-ameliorates-pathological-phenotypes-in-mouse-and-cellular-models-of-huntingtons-disease/
Website entry (mbexc.de)
Linked Antibodies
| PID | AG | Type | Antigen symbol | Antibody Registry ID | Name |
|---|
| primary-0107 |  | primary | MAP2 | AB_2138178, AB_350528 | MAP2 Antibody |
| primary-0160 |  | primary | TUBA4A | AB_477593 | Anti-α-Tubulin antibody |
| primary-0499 |  | primary | CASP3 | AB_331439 | Caspase-3 Antibody |
| primary-0681 |  | primary | HTT | AB_177645 | Anti-Huntingtin Protein Antibody |
| primary-0984 |  | primary | ACTB | AB_306371 | Anti-beta Actin antibody [mAbcam 8226] - Loading Control |
| primary-1878 | | primary | mCherry | AB_2333093 | mCherry Goat Polyclonal Antibody |
| primary-1879 | | primary | PSD95 | AB_2886821 | PSD95 antibody |
| primary-1880 | | primary | VGluT1 | AB_2923539 | Anti-VGluT1 antibody [N28-9] |
| primary-1881 | | primary | Iba1 | AB_10972670 | Anti-Iba1 antibody |
| primary-1882 | | primary | NeuN | AB_2802653 | NeuN Monoclonal Antibody (1B7) |
| primary-1883 | | primary | PDE10A | AB_2927552 | Anti-PDE10A antibody [EPR22383] |
| primary-1884 | | primary | DARPP32 | AB_731843 | Anti-DARPP32 antibody [EP720Y] |
| primary-1885 | | primary | HTT | AB_10827977 | Huntingtin (D7F7) XP® Rabbit mAb |
