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Publication

Property	Value
Working Groups	RG Gollisch, RG Möbius, RG Outeiro, RG Urlaub
Subproject	RA2.2
Open Access	Yes
Publication Type	Preprint
Peer Reviewed	No
DOI	10.1101/2021.07.18.452825
Publication Year	2021
Title	Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells
Journal	bioRxiv
ISSN	no ISSN (NLM ID:101680187)
URL	http://dx.doi.org/10.1101/2021.07.18.452825
Journal Abbreviation	bioRxiv
Extra	Final article published in Journal of Parkinson's Disease here: doi:10.3233/jpd-223516
Authors	Brás IC, Khani MH, Vasili E, Möbius W, Riedel D, Parfentev I, Gerhardt E, Fahlbusch C, Urlaub H, Zweckstetter M, Gollisch T, Outeiro TF
First Author	Brás IC
Last Author	Outeiro TF

External Resources

biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2021.07.18.452825v1.full.pdf Article fulltext

gro-2/100391http://resolver.sub.uni-goettingen.de/purl?gro-2/100391 GRO.publications identifier

10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)

0000-0001-8451-8891https://orcid.org/0000-0001-8451-8891 ORCID identifier (Ines Caldeira Bras)

0000-0003-3123-7054https://orcid.org/0000-0003-3123-7054 ORCID identifier (Mohammad Hossein Khani)

0000-0001-9150-0104https://orcid.org/0000-0001-9150-0104 ORCID identifier (Eftychia Vasili)

0000-0002-2902-7165https://orcid.org/0000-0002-2902-7165 ORCID identifier (Wiebke Möbius)

0000-0003-2970-6894https://orcid.org/0000-0003-2970-6894 ORCID identifier (Dietmar Riedel)

0000-0002-0203-2167https://orcid.org/0000-0002-0203-2167 ORCID identifier (Iwan Parfentev)

0000-0003-1837-5233https://orcid.org/0000-0003-1837-5233 ORCID identifier (Henning Urlaub)

0000-0002-2536-6581https://orcid.org/0000-0002-2536-6581 ORCID identifier (Markus Zweckstetter)

0000-0003-3998-533Xhttps://orcid.org/0000-0003-3998-533X ORCID identifier (Tim Gollisch)

0000-0003-1679-1727https://orcid.org/0000-0003-1679-1727 ORCID identifier (Tiago Fleming Outeiro)

128https://sfb1286.uni-goettingen.de/literature/publications/128 Published Data Registry entry (CRC 1286)

652https://prod.mbexc.uni-goettingen.de/literature/publications/652 Published Data Registry entry (MBExC, final article)

1/368https://mbexc.uni-goettingen.de/archive/1/368 Research Data Archive (supplemental material)

043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)

03e76ya46https://ror.org/03e76ya46 ROR identifier (03e76ya46, Max Planck Institute for Biophysical Chemistry)

04a7f6w43https://ror.org/04a7f6w43 ROR identifier (04a7f6w43, Max Planck Institute of Experimental Medicine)

05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

01kj2bm70https://ror.org/01kj2bm70 ROR identifier (01kj2bm70, Newcastle University)

021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)

SCR_008520https://scicrunch.org/resolver/SCR_008520 SciCrunch identifier (RRID:SCR_008520, FlowJo)

SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)

SCR_016422https://scicrunch.org/resolver/SCR_016422 SciCrunch identifier (RRID:SCR_016422, KiloSort)

SCR_013673https://scicrunch.org/resolver/SCR_013673 SciCrunch identifier (RRID:SCR_013673, Leica Application Suite X)

SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)

SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)

biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/07/19/2021.07.18.452825/DC1/embed/media-1.pdf?download=true Supplemental material

mbexc.de...cells/https://mbexc.de/common-molecular-mechanisms-underlie-the-transfer-of-alpha-synuclein-tau-and-huntingtinand-modulate-spontaneous-activityin-neuronal-cells/ Website entry (mbexc.de)

Linked Antibodies

PID	Type	Antigen symbol	Antibody Registry ID	Name
primary-0280	primary	GFAP	AB_10013382	Glial Fibrillary Acidic Protein (Multipurpose) antibody
primary-0367	primary	SNCA	AB_869973	Recombinant Anti-Alpha-synuclein (phospho S129) antibody
primary-0368	primary	SNCA	AB_398108	a-Synuclein antibody
primary-0384	primary	TAU	AB_10013724	Polyclonal Rabbit Anti-Human Tau
primary-0385	primary	ACTB	AB_476744	Monoclonal Anti-β-Actin antibody
primary-0389	primary	MAPT	AB_2314654	Tau Monoclonal Antibody
primary-0680	primary	TUBA1A	AB_2212272	Alpha-Tubulin antibody
primary-0681	primary	HTT	AB_177645	Anti-Huntingtin Protein Antibody
primary-0682	primary	AIF1	AB_2224402	Anti-Iba1 antibody
primary-0683	primary	LC3	AB_2274121	Anti-LC3 pAb
primary-0684	primary	MAP2	AB_297885	Anti-MAP2 antibody
primary-0685	primary	SYP	AB_887905	Synaptophysin 1 antibody
primary-0780	primary	PDCD6IP	AB_10899268	Anti-ALIX antibody
primary-0781	primary	ANXA2		Recombinant Anti-Annexin-2/ANXA2 antibody
primary-0782	primary	AGE	AB_447638	Anti-AGE antibody
primary-0783	primary	FLOT1	AB_2773040	Flotillin-1 (D2V7J) XP® Rabbit mAb
primary-0784	primary	GFP	AB_390913	Anti-GFP antibody
primary-0785	primary	NOS2	AB_310179	Anti-iNOS/NOS II Antibody
primary-0786	primary	AIF1	AB_2636859	Recombinant Anti-Iba1 antibody
primary-0787	primary	SQSTM1	AB_2050336	Anti-SQSTM1 / p62 antibody
primary-0788	primary	USP19 KIAA0891	AB_1078839	USP19/ZMYND9 Antibody
secondary-0021	secondary		AB_2534102	Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
secondary-0022	secondary		AB_2535853	Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555
secondary-0392	secondary		AB_2535792	Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
secondary-0394	secondary		AB_141607	Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
secondary-0477	secondary		AB_162543	Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 555
secondary-0491	secondary		AB_2536180	Donkey anti-Mouse IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 555
secondary-0571	secondary		AB_2535794	Donkey anti-Rat IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 488
secondary-0686	secondary		AB_2535718	Goat anti-Mouse IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 633
secondary-0687	secondary		AB_2535739	Donkey anti-Goat IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 633
secondary-0779	secondary		AB_2534018	Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor 680
secondary-0789	secondary		AB_220030	Rat IgG (H&L) Antibody

Technical Support: menoci@medizin.uni-goettingen.de

Department of Medical Informatics
University Medical Center Göttingen
Imprint

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External Resources

Linked Antibodies

Technical support

Links

Spokesperson

Prof. Dr. Tobias Moser

Spokesperson of Cluster of Excellence