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Publication
PropertyValue
Working Groups RG Wollnik
SubprojectNone
Open AccessOpen Access Yes
Publication TypeJournal Article
Peer ReviewedYes
PMIDPubMed ID 39253995
DOIDOI 10.1002/1878-0261.13725
Publication Year2024
TitleKRASG12C‐inhibitor‐based combination therapies for pancreatic cancer: insights from drug screening
JournalMolecular Oncology
ISSN1574-7891
eISSN1878-0261
URL http://dx.doi.org/10.1002/1878-0261.13725
Journal AbbreviationMol Oncol
AuthorsTapia Contreras C, Falke JD, Seifert D, Schneider C, Krauß L, Fang X, Müller D, Demirdizen E, Spitzner M, De Oliveira T, Schneeweis C, Gaedcke J, Kaulfuß S, Mirzakhani K, Wollnik B, Conrads K, Beißbarth T, Salinas G, Hügel J, Beyer N, Rheinländer S, Sax U, Wirth M, Conradi L, Reichert M, Ellenrieder V, Ströbel P, Ghadimi M, Grade M, Saur D, Hessmann E, Schneider G
First AuthorTapia Contreras C
Last AuthorSchneider G

 External Resources

 febs.onl...d=true  Article fulltext

 gro-2/145530  GRO.publications identifier

 451668  NCBI PubChem (451668, Decitabine)

 54761306  NCBI PubChem (54761306, Ceralasertib)

 92136227  NCBI PubChem (92136227, N1-((4-(4-isopropoxyphenyl)-1H-pyrrol-3-yl)methyl)-N1-methylethane-1,2-diamine)

 118238370  NCBI PubChem (118238370, Batoprotafib)

 137278711  NCBI PubChem (137278711, Sotorasib)

 138911318  NCBI PubChem (138911318, N-((R)-1-(3-amino-5-(trifluoromethyl)phenyl)ethyl)-7-methoxy-2-methyl-6-(((S)-tetrahydrofuran-3-yl)oxy)quinazolin-4-amine)

 Nintedanib  NCBI PubChem (Nintedanib)

 9606  NCBI taxonomy (human, Homo sapiens)

 0000-0001-6231-7431  ORCID identifier (Denise Müller)

 0000-0003-2577-9711  ORCID identifier (Silke Kaulfuß)

 0000-0003-2589-0364  ORCID identifier (Bernd Wollnik)

 0009-0006-4536-8564  ORCID identifier (Karly Conrads)

 0000-0001-6509-2143  ORCID identifier (Tim Beißbarth)

 0000-0001-8269-2669  ORCID identifier (Gabriela Salinas-Riester)

 0000-0002-4183-1287  ORCID identifier (Jonas Hügel)

 0000-0002-5489-3575  ORCID identifier (Nils Hendrik Beyer)

 0000-0002-5406-4427  ORCID identifier (Sophia Rheinländer)

 0000-0002-8188-3495  ORCID identifier (Ulrich Sax)

 0000-0002-8340-0872  ORCID identifier (Matthias Wirth)

 0000-0002-9488-1018  ORCID identifier (Lena-Christin Conradi)

 0000-0001-9981-8571  ORCID identifier (Volker Ellenrieder)

 0000-0002-8528-8060  ORCID identifier (Philipp Ströbel)

 0000-0001-8208-1526  ORCID identifier (Michael Ghadimi)

 0000-0001-5874-0210  ORCID identifier (Dieter Saur)

 0000-0002-9462-1291  ORCID identifier (Elisabeth Hessmann)

 0000-0003-1840-4508  ORCID identifier (Günter Schneider)

 1/507  Research Data Archive (supplemental material)

 001w7jn25  ROR identifier (001w7jn25, Charité - Universitätsmedizin Berlin)

 05xy1nn52  ROR identifier (05xy1nn52, Multiscale Bioimaging)

 04jc43x05  ROR identifier (04jc43x05, Rechts der Isar Hospital)

 02kkvpp62  ROR identifier (02kkvpp62, Technical University of Munich)

 021ft0n22  ROR identifier (021ft0n22, University Medical Center Göttingen)

 CVCL_0152  SciCrunch identifier (RRID:CVCL_0152, AsPC-1)

 CVCL_0045  SciCrunch identifier (RRID:CVCL_0045, HEK293)

 CVCL_0063  SciCrunch identifier (RRID:CVCL_0063, HEK293T)

 CVCL_0428  SciCrunch identifier (RRID:CVCL_0428, MIA PaCa-2)

 CVCL_4892  SciCrunch identifier (RRID:CVCL_4892, PS-1 [Human urinary bladder carcinoma])

 SCR_019214  SciCrunch identifier (RRID:SCR_019214, biomaRt)

 SCR_017133  SciCrunch identifier (RRID:SCR_017133, ClustVis)

 SCR_012802  SciCrunch identifier (RRID:SCR_012802, edgeR)

 SCR_002344  SciCrunch identifier (RRID:SCR_002344, Ensembl)

 SCR_000141  SciCrunch identifier (RRID:SCR_000141, FastQ Screen)

 SCR_014583  SciCrunch identifier (RRID:SCR_014583, FastQC)

 SCR_002798  SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

 SCR_021058  SciCrunch identifier (RRID:SCR_021058, GSVA)

 SCR_011867  SciCrunch identifier (RRID:SCR_011867, htseq-count)

 SCR_016381  SciCrunch identifier (RRID:SCR_016381, Illumina NextSeq 550 System)

 SCR_005484  SciCrunch identifier (RRID:SCR_005484, Kraken)

 SCR_014982  SciCrunch identifier (RRID:SCR_014982, MultiQC)

 SCR_001905  SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)

 SCR_004463  SciCrunch identifier (RRID:SCR_004463, STAR)

 SCR_011848  SciCrunch identifier (RRID:SCR_011848, Trimmomatic)

 febs.onl...S4.pdf  Supplemental material (figure)

 goeseek.gwdguser.de/studies/197  Supplemental material (goeseek study)

 febs.onl...1.xlsx  Supplemental material (table)

Linked Antibodies

PIDAGTypeAntigen symbolAntibody Registry IDName
primary-1703primaryKRASAB_1842235Monoclonal Anti-KRAS antibody produced in mouse
primary-1704primaryMK03AB_2315112Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204) (D13.14.4E) XP® Rabbit mAb
primary-1705primaryAB_10693601p44/42 MAPK (Erk1/2) (137F5) Rabbit mAb (HRP Conjugate)
primary-1706primaryHSP90AB_675659HSP90 alpha/beta Antibody (F-8)
secondary-1707secondaryAB_10262463Rabbit IgG (H+L chain) Goat Polyclonal Antibody
secondary-1708secondaryAB_10266129Mouse IgG (H+L chain) Rabbit Polyclonal Antibody