| Property |
Value |
| Working Groups |
RG Cyganek, 
RG Zimmermann |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2025.04.29.650605 |
| Publication Year |
2025 |
| Title |
SarcAsM: AI-based multiscale analysis of sarcomere organization and contractility in cardiomyocytes |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.1101/2025.04.29.650605 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Not yet finally published in a peer-reviewed journal, IRTG 1816, RTG 2824 |
| Authors |
Härtter D, Hauke L, Driehorst T, Long Y, Bao G, Primeßnig A, Berečić B, Cyganek L, Tiburcy M, Schmidt CF, Zimmermann W |
| First Author |
Härtter D |
| Last Author |
Zimmermann W |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2025.04.29.650605v1.full.pdf Article fulltext
sfb1002....ne=358https://sfb1002.med.uni-goettingen.de/production/cellmodel/cell-line/view?tab=gen_mod&line=358 Cell Model Catalogue (RUCDRi002-A-3)
2/149893https://publications.goettingen-research-online.de/handle/2/149893 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0002-9582-6141https://orcid.org/0000-0002-9582-6141 ORCID identifier (Daniel Härtter)
0000-0003-0777-6859https://orcid.org/0000-0003-0777-6859 ORCID identifier (Lara Hauke)
0000-0001-9120-1382https://orcid.org/0000-0001-9120-1382 ORCID identifier (Lukas Cyganek)
0000-0002-6942-6275https://orcid.org/0000-0002-6942-6275 ORCID identifier (Malte Tiburcy)
0000-0003-2864-6973https://orcid.org/0000-0003-2864-6973 ORCID identifier (Christoph F. Schmidt)
0000-0003-1190-4040https://orcid.org/0000-0003-1190-4040 ORCID identifier (Wolfram Hubertus Zimmermann)
556https://sfb1002.med.uni-goettingen.de/production/literature/publications/556 Published Data Registry entry (CRC 1002)
1/607https://mbexc.uni-goettingen.de/archive/1/607 Research Data Archive (supplemental material)
00py81415https://ror.org/00py81415 ROR identifier (00py81415, Duke University)
01s1h3j07https://ror.org/01s1h3j07 ROR identifier (01s1h3j07, Fraunhofer Institute for Translational Medicine and Pharmacology)
031t5w623https://ror.org/031t5w623 ROR identifier (031t5w623, German Centre for Cardiovascular Research)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
SCR_002630https://scicrunch.org/resolver/SCR_002630 SciCrunch identifier (RRID:SCR_002630, GitHub)
SCR_020233https://scicrunch.org/resolver/SCR_020233 SciCrunch identifier (RRID:SCR_020233, Leica TCS SP5 Broadband Confocal Laser Scanning Microscope)
SCR_022765https://scicrunch.org/resolver/SCR_022765 SciCrunch identifier (RRID:SCR_022765, Napari)
SCR_008394https://scicrunch.org/resolver/SCR_008394 SciCrunch identifier (RRID:SCR_008394, Python)
SCR_018536https://scicrunch.org/resolver/SCR_018536 SciCrunch identifier (RRID:SCR_018536, PyTorch)
SCR_021142https://scicrunch.org/resolver/SCR_021142 SciCrunch identifier (RRID:SCR_021142, scikit-image)
SCR_002577https://scicrunch.org/resolver/SCR_002577 SciCrunch identifier (RRID:SCR_002577, scikit-learn)
SCR_023270https://scicrunch.org/resolver/SCR_023270 SciCrunch identifier (RRID:SCR_023270, Yokogawa CellVoyager CV8000)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/05/04/2025.04.29.650605/DC1/embed/media-1.pdf?download=true Supplemental material
github.c...e-unethttps://github.com/danihae/bio-image-unet Supplemental material (code)
github.com/danihae/SarcAsMhttps://github.com/danihae/SarcAsM Supplemental material (code)
pypi.org/project/sarc-asm/https://pypi.org/project/sarc-asm/ Supplemental material (code)
sarcasm.readthedocs.io/https://sarcasm.readthedocs.io/ Supplemental material (code, documentation)
hpscreg....i002-Ahttps://hpscreg.eu/cell-line/RUCDRi002-A Supplemental material (hpscreg identifier)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/05/04/2025.04.29.650605/DC2/embed/media-2.mp4?download=true Supplemental material (video)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/05/04/2025.04.29.650605/DC3/embed/media-3.mp4?download=true Supplemental material (video)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/05/04/2025.04.29.650605/DC4/embed/media-4.mp4?download=true Supplemental material (video)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/05/04/2025.04.29.650605/DC5/embed/media-5.mp4?download=true Supplemental material (video)
mbexc.de...cytes/https://mbexc.de/sarcasm-ai-based-multiscale-analysis-of-sarcomere-organization-and-contractility-in-cardiomyocytes/ Website entry (mbexc.de)
10.5281/zenodo.8232838https://doi.org/10.5281/zenodo.8232838 Zenodo identifier (10.5281/zenodo.8232838)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0102 |
|
primary |
ACTN2 |
AB_476766 |
Anti-α-Actinin (Sarcomeric) antibody |
| primary-0797 |
|
primary |
GAPDH |
AB_2107436 |
GAPDH Monoclonal antibody |
| secondary-1003 |
 |
secondary |
|
AB_258167 |
Anti-Mouse IgG (whole molecule)–Peroxidase antibody |