| Property |
Value |
| Working Groups |
RG Fischer, 
RG Hasenfuß, 
RG Wollnik, 
RG Zimmermann |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
39880949 |
| DOI |
10.1038/s41586-024-08463-0 |
| Publication Year |
2025 |
| Title |
Engineered heart muscle allografts for heart repair in primates and humans |
| Journal |
Nature |
| ISSN |
0028-0836 |
| eISSN |
1476-4687 |
| URL |
https://www.nature.com/articles/s41586-024-08463-0 |
| Journal Abbreviation |
Nature |
| Authors |
Jebran AF, Seidler T, Tiburcy M, Daskalaki M, Kutschka I, Fujita B, Ensminger S, Bremmer F, Moussavi A, Yang H, Qin X, Mißbach S, Drummer C, Baraki H, Boretius S, Hasenauer C, Nette T, Kowallick J, Ritter CO, Lotz J, Didié M, Mietsch M, Meyer T, Kensah G, Krüger D, Sakib MS, Kaurani L, Fischer A, Dressel R, Rodriguez-Polo I, Stauske M, Diecke S, Maetz-Rensing K, Gruber-Dujardin E, Bleyer M, Petersen B, Roos C, Zhang L, Walter L, Kaulfuß S, Yigit G, Wollnik B, Levent E, Roshani B, Stahl-Henning C, Ströbel P, Legler T, Riggert J, Hellenkamp K, Voigt JU, Hasenfuß G, Hinkel R, Wu JC, Behr R, Zimmermann WH |
| First Author |
Jebran AF |
| Last Author |
Zimmermann WH |
External Resources
27077https://www.addgene.org/27077 Addgene identifier (27077, reused)
27078https://www.addgene.org/27078 Addgene identifier (27078, reused)
27080https://www.addgene.org/27080 Addgene identifier (27080, reused)
nature.c...-0.pdfhttps://www.nature.com/articles/s41586-024-08463-0.pdf Article fulltext
NCT04396899https://clinicaltrials.gov/ct2/show/NCT04396899 ClinicalTrials ID (NCT04396899)
2/147572http://resolver.sub.uni-goettingen.de/purl?2/147572 GRO.publications identifier
GCA_000001405.22https://www.ncbi.nlm.nih.gov/datasets/genome/GCA_000001405.22 NCBI genome identifier (GCA_000001405.22)
GSE276021https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE276021 NCBI GEO Dataset (GSE276021)
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
9544https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9544 NCBI taxonomy (Rhesus monkey, Macaca mulatta)
0000-0003-4281-0960https://orcid.org/0000-0003-4281-0960 ORCID identifier (Ahmad-Fawad Jebran)
0000-0002-6158-5087https://orcid.org/0000-0002-6158-5087 ORCID identifier (Tim Seidler)
0000-0002-6942-6275https://orcid.org/0000-0002-6942-6275 ORCID identifier (Malte Tiburcy)
0000-0002-7358-3513https://orcid.org/0000-0002-7358-3513 ORCID identifier (Ingo Kutschka)
0000-0002-3262-7727https://orcid.org/0000-0002-3262-7727 ORCID identifier (Buntaro Fujita)
0000-0002-9508-3261https://orcid.org/0000-0002-9508-3261 ORCID identifier (Stephan Ensminger)
0000-0003-0367-6527https://orcid.org/0000-0003-0367-6527 ORCID identifier (Felix Bremmer)
0000-0002-6189-8622https://orcid.org/0000-0002-6189-8622 ORCID identifier (Amir Moussavi)
0000-0002-1382-2228https://orcid.org/0000-0002-1382-2228 ORCID identifier (Charis Drummer)
0000-0003-3938-6484https://orcid.org/0000-0003-3938-6484 ORCID identifier (Hassina Baraki)
0000-0003-2792-7423https://orcid.org/0000-0003-2792-7423 ORCID identifier (Susann Boretius)
0000-0002-3580-619Xhttps://orcid.org/0000-0002-3580-619X ORCID identifier (Johannes T. Kowallick)
0000-0002-1412-2741https://orcid.org/0000-0002-1412-2741 ORCID identifier (Joachim Lotz)
0000-0002-3520-5394https://orcid.org/0000-0002-3520-5394 ORCID identifier (Matthias Mietsch)
0000-0002-0521-6711https://orcid.org/0000-0002-0521-6711 ORCID identifier (Tim Meyer)
0000-0003-0219-8279https://orcid.org/0000-0003-0219-8279 ORCID identifier (George Kensah)
0000-0003-1950-9547https://orcid.org/0000-0003-1950-9547 ORCID identifier (Dennis Manfred Krüger)
0000-0002-0903-9791https://orcid.org/0000-0002-0903-9791 ORCID identifier (Md. Sadman Sakib)
0000-0002-2304-6111https://orcid.org/0000-0002-2304-6111 ORCID identifier (Lalit Kaurani)
0000-0001-8546-1161https://orcid.org/0000-0001-8546-1161 ORCID identifier (André Fischer)
0000-0002-1651-1214https://orcid.org/0000-0002-1651-1214 ORCID identifier (Ralf Dressel)
0000-0003-1254-4972https://orcid.org/0000-0003-1254-4972 ORCID identifier (Ignacio Rodriguez-Polo)
0000-0003-3036-8714https://orcid.org/0000-0003-3036-8714 ORCID identifier (Michael Stauske)
0000-0002-5219-5992https://orcid.org/0000-0002-5219-5992 ORCID identifier (Sebastian Diecke)
0000-0002-8090-9972https://orcid.org/0000-0002-8090-9972 ORCID identifier (Eva Gruber-Dujardin)
0009-0009-6409-0790https://orcid.org/0009-0009-6409-0790 ORCID identifier (Martina Bleyer)
0000-0001-7121-8259https://orcid.org/0000-0001-7121-8259 ORCID identifier (Christian Roos)
0000-0002-8829-0588https://orcid.org/0000-0002-8829-0588 ORCID identifier (Liye Zhang)
0000-0001-9408-3131https://orcid.org/0000-0001-9408-3131 ORCID identifier (Lutz Walter)
0000-0003-2577-9711https://orcid.org/0000-0003-2577-9711 ORCID identifier (Silke Kaulfuß)
0000-0003-2777-0198https://orcid.org/0000-0003-2777-0198 ORCID identifier (Gökhan Yigit)
0000-0003-2589-0364https://orcid.org/0000-0003-2589-0364 ORCID identifier (Bernd Wollnik)
0000-0003-0109-9703https://orcid.org/0000-0003-0109-9703 ORCID identifier (Berit Roshani)
0000-0001-5545-8498https://orcid.org/0000-0001-5545-8498 ORCID identifier (Christiane Stahl-Henning)
0000-0002-8528-8060https://orcid.org/0000-0002-8528-8060 ORCID identifier (Philipp Ströbel)
0000-0002-1408-5397https://orcid.org/0000-0002-1408-5397 ORCID identifier (Tobias Legler)
0000-0002-0575-1888https://orcid.org/0000-0002-0575-1888 ORCID identifier (Jens-Uwe Voigt)
0000-0002-5942-361Xhttps://orcid.org/0000-0002-5942-361X ORCID identifier (Gerd Hasenfuß)
0000-0002-2936-0400https://orcid.org/0000-0002-2936-0400 ORCID identifier (Rabea Hinkel)
0000-0002-6068-8041https://orcid.org/0000-0002-6068-8041 ORCID identifier (Joseph C. Wu)
0000-0001-8816-6619https://orcid.org/0000-0001-8816-6619 ORCID identifier (Rüdiger Behr)
0000-0003-1190-4040https://orcid.org/0000-0003-1190-4040 ORCID identifier (Wolfram Hubertus Zimmermann)
552https://sfb1002.med.uni-goettingen.de/production/literature/publications/552 Published Data Registry entry (CRC 1002)
1/569https://mbexc.uni-goettingen.de/archive/1/569 Research Data Archive (supplemental material)
01s1h3j07https://ror.org/01s1h3j07 ROR identifier (01s1h3j07, Fraunhofer Institute for Translational Medicine and Pharmacology)
031t5w623https://ror.org/031t5w623 ROR identifier (031t5w623, German Centre for Cardiovascular Research)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
02f99v835https://ror.org/02f99v835 ROR identifier (02f99v835, German Primate Center)
05f950310https://ror.org/05f950310 ROR identifier (05f950310, KU Leuven)
04p5ggc03https://ror.org/04p5ggc03 ROR identifier (04p5ggc03, Max Delbrück Center for Molecular Medicine)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
00f54p054https://ror.org/00f54p054 ROR identifier (00f54p054, Stanford University)
01tvm6f46https://ror.org/01tvm6f46 ROR identifier (01tvm6f46, University Hospital Schleswig-Holstein)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
033eqas34https://ror.org/033eqas34 ROR identifier (033eqas34, University of Giessen)
SCR_017344https://scicrunch.org/resolver/SCR_017344 SciCrunch identifier (RRID:SCR_017344, Cell Ranger)
SCR_008520https://scicrunch.org/resolver/SCR_008520 SciCrunch identifier (RRID:SCR_008520, FlowJo)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_016381https://scicrunch.org/resolver/SCR_016381 SciCrunch identifier (RRID:SCR_016381, Illumina NextSeq 550 System)
SCR_016137https://scicrunch.org/resolver/SCR_016137 SciCrunch identifier (RRID:SCR_016137, Microsoft Excel)
SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM1_ESM.pdf Supplemental material
goeseek.gwdguser.de/studies/224https://goeseek.gwdguser.de/studies/224 Supplemental material (goeseek study)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM3_ESM.pdf Supplemental material (peer review)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM2_ESM.pdf Supplemental material (reporting summary)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM4_ESM.xlsx Supplemental material (table)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM5_ESM.xlsx Supplemental material (table)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM6_ESM.xlsx Supplemental material (table)
static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM7_ESM.mp4 Supplemental material (video)
static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM8_ESM.mp4 Supplemental material (video)
static-c...SM.mp4https://static-content.springer.com/esm/art%3A10.1038%2Fs41586-024-08463-0/MediaObjects/41586_2024_8463_MOESM9_ESM.mp4 Supplemental material (video)
mbexc.de...umans/https://mbexc.de/engineered-heart-muscle-allografts-for-heart-repair-in-primates-and-humans/ Website entry (mbexc.de)