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Publication

Property	Value
Working Groups	RG Jakobs, RG Rehling, RG Richter-Dennerlein
Subproject	RA1.1
Open Access	Yes
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	34969438
DOI	10.7554/elife.68213
Publication Year	2021
Title	Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
Journal	eLife
ISSN	2050-084X
eISSN	2050-084X
URL	http://dx.doi.org/10.7554/elife.68213
Volume	10
Journal Abbreviation	eLife
Extra	FOR2848 (P01, P04)
Authors	Dennerlein S, Poerschke S, Oeljeklaus S, Wang C, Richter-Dennerlein R, Sattmann J, Bauermeister D, Hanitsch E, Stoldt S, Langer T, Jakobs S, Warscheid B, Rehling P
First Author	Dennerlein S
Last Author	Rehling P

External Resources

elifesci.../68213https://elifesciences.org/articles/68213 Article fulltext

gro-2/98968http://resolver.sub.uni-goettingen.de/purl?gro-2/98968 GRO.publications identifier

0000-0002-8901-0242https://orcid.org/0000-0002-8901-0242 ORCID identifier (Sven Dennerlein)

0000-0003-0786-4090https://orcid.org/0000-0003-0786-4090 ORCID identifier (Sabine Poerschke)

0000-0001-8908-4295https://orcid.org/0000-0001-8908-4295 ORCID identifier (Silke Oeljeklaus)

0000-0001-8904-1543https://orcid.org/0000-0001-8904-1543 ORCID identifier (Ricarda Richter-Dennerlein)

0000-0003-1250-1462https://orcid.org/0000-0003-1250-1462 ORCID identifier (Thomas Langer)

0000-0002-8028-3121https://orcid.org/0000-0002-8028-3121 ORCID identifier (Stefan Jakobs)

0000-0001-5096-1975https://orcid.org/0000-0001-5096-1975 ORCID identifier (Bettina Warscheid)

0000-0001-5661-5272https://orcid.org/0000-0001-5661-5272 ORCID identifier (Peter Rehling)

166https://sfb1190.med.uni-goettingen.de/production/literature/publications/166 Published Data Registry entry (CRC 1190)

7https://for2848.gwdguser.de/literature/publications/7 Published Data Registry entry (FOR 2848)

1/20https://mbexc.uni-goettingen.de/archive/1/20 Research Data Archive (supplemental material)

01s1h3j07https://ror.org/01s1h3j07 ROR identifier (01s1h3j07, Fraunhofer Institute forTranslational Medicine and Pharmacology)

04xx1tc24https://ror.org/04xx1tc24 ROR identifier (04xx1tc24, Max Planck Institute for Biology of Ageing)

03e76ya46https://ror.org/03e76ya46 ROR identifier (03e76ya46, Max Planck Institute for Biophysical Chemistry)

05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)

CVCL_U421https://scicrunch.org/resolver/CVCL_U421 SciCrunch identifier (RRID:CVCL_U421, Flp-In-293)

CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)

CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)

SCR_010519https://scicrunch.org/resolver/SCR_010519 SciCrunch identifier (RRID:SCR_010519, Geneious)

SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)

SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)

SCR_014246https://scicrunch.org/resolver/SCR_014246 SciCrunch identifier (RRID:SCR_014246, ImageQuant)

SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)

goeseek.gwdguser.de/studies/118https://goeseek.gwdguser.de/studies/118 Supplemental material (goeseek study)

bio-prot...m=s4-1https://bio-protocol.org/eLIFErap68213?item=s4-1 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-2https://bio-protocol.org/eLIFErap68213?item=s4-2 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-3https://bio-protocol.org/eLIFErap68213?item=s4-3 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-4https://bio-protocol.org/eLIFErap68213?item=s4-4 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-5https://bio-protocol.org/eLIFErap68213?item=s4-5 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-6https://bio-protocol.org/eLIFErap68213?item=s4-6 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-7https://bio-protocol.org/eLIFErap68213?item=s4-7 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-8https://bio-protocol.org/eLIFErap68213?item=s4-8 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...m=s4-9https://bio-protocol.org/eLIFErap68213?item=s4-9 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...=s4-10https://bio-protocol.org/eLIFErap68213?item=s4-10 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...=s4-11https://bio-protocol.org/eLIFErap68213?item=s4-11 Supplemental material (protocol on request at bio-protocol.org)

bio-prot...=s4-12https://bio-protocol.org/eLIFErap68213?item=s4-12 Supplemental material (protocol on request at bio-protocol.org)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig1-data1-v1.zip Supplemental material (source data)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig2-data1-v1.zip Supplemental material (source data)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig3-data1-v1.zip Supplemental material (source data)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig4-data1-v1.zip Supplemental material (source data)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig5-data1-v1.zip Supplemental material (source data)

cdn.elif...v1.ziphttps://cdn.elifesciences.org/articles/68213/elife-68213-fig6-data1-v1.zip Supplemental material (source data)

mbexc.de...ctors/https://mbexc.de/defining-the-interactome-of-the-human-mitochondrial-ribosome-identifies-smim4-and-tmem223-as-respiratory-chain-assembly-factors/ Website entry (mbexc.de)

Linked Antibodies

PID	Type	Antigen symbol	Antibody Registry ID	Name
primary-0165	primary	MRPS18B	AB_2146368	MRPS18B antibody
primary-0298	primary	MRPS14	AB_2878240	MRPS14 Polyclonal antibody
primary-0300	primary	MRPS16	AB_2180166	MRPS16 Polyclonal antibody
primary-0303	primary	MRPL3	AB_10639509	MRPL3 Polyclonal antibody
primary-0315	primary	TIMM44	AB_2204679	TIMM44 Polyclonal antibody
primary-0507	primary	FLAG	AB_259529	Monoclonal ANTI-FLAG® M2 antibody
primary-0878	primary	PHB	AB_2164476	Prohibitin Polyclonal antibody
primary-0879	primary	STOML2	AB_2286822	STOML2 Polyclonal antibody
primary-1312	primary			anti-RIESKE
primary-1313	primary	COX4		anti-COX4-I
primary-1314	primary	NDUFA9		anti-NDUFA9
primary-1316	primary	uL23m		anti-uL23m
primary-1317	primary	COX6A		anti-COX6A
primary-1319	primary	TIM21		anti-TIM21
primary-1320	primary	MITRAC12		anti-MITRAC12
primary-1321	primary	NDUFB8		anti-NDUFB8
primary-1322	primary	AFG3L2		anti-AFG3L2
primary-1323	primary	C12ORF62		anti-C12ORF62
primary-1328	primary	C12ORF73		anti-C12ORF73
primary-1329	primary	CYTB		anti-CYTB
primary-1334	primary	TMEM223		TMEM223
primary-1335	primary	SMIM4		SMIM4
primary-1336	primary	TMEM177		TMEM177
primary-1337	primary	TIM44		TIM44
primary-1338	primary	SLIRP		SLIRP
primary-1339	primary	YME1L		YME1L
primary-1340	primary	MITRAC7		MITRAC7
primary-1341	primary	COX1		COX1
primary-1342	primary	uL1m		uL1m
primary-1343	primary	TOM70		TOM70
primary-1344	primary	TACO1		TACO1
primary-1345	primary	MITRAC15		MITRAC15
primary-1346	primary	SDHA		SDHA
primary-1347	primary	ATP5B		ATP5B
primary-1348	primary	TIM23		TIM23
primary-1349	primary	SCO2		SCO2
primary-1350	primary	FAM36A		FAM36A
primary-1351	primary	SURF1		SURF1

Technical Support: menoci@medizin.uni-goettingen.de

Department of Medical Informatics
University Medical Center Göttingen
Imprint

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External Resources

Linked Antibodies

Technical support

Links

Spokesperson

Prof. Dr. Tobias Moser

Spokesperson of Cluster of Excellence