Published Data Registry

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Versatile Microfluidics Platform for Enhanced Multitarget Super-Resolution Microscopy (Open Access) Basak S, Vu K, (...), Tsukanov R ACS Nano 2026
Restoring Shugoshin 1 reduces chromosome errors in human eggs (Open Access) Schuh M, Saha D, (...), Elder K bioRxiv 2026
Molecular genotype-phenotype correlation in ACTB- and ACTG1-related non-muscle actinopathies (Open Access) Di Donato N, NMA Consortium, (...), Banka S American Journal of Human Genetics 2026
DNA-PAINT resolves E-cadherin-independent cross-junctional F-actin organization in Drosophila embryonic tissue Häring M, Zhang Y, (...), Kong D Biophysical Journal 2026
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity (Open Access) Hümmert S, de Faria JP, (...), Werner HB Glia 2026
Munc13-1 couples DAG and Ca2+ signaling to dynamic vesicle priming, synaptic short-term plasticity, and posttetanic potentiation (Open Access) Ranjan M, Lin K, (...), Taschenberger H Science Advances 2026
Household size can explain 40% of the variance in cumulative COVID-19 incidence across Europe (Open Access) Contreras S, Dönges P, (...), Priesemann V arXiv 2026
Multi-scale transcriptomic integration reveals cell-type immune networks and lncRNA remodeling in Alzheimer’s disease (Open Access) Silva JAC, Gertig M, (...), Fischer A bioRxiv 2026
Visualizing the multidimensional landscape of biological variation in modern microscopy (Open Access) Müller GF, Göpel T, Scherf N, Huisken J Frontiers in Bioinformatics 2026
The Nonadiabatic Nature of the Substituent Effects in Azobenzene (Open Access) van der Wal JJ, Peshkov RY, Steen JD, Simeth NA, Crespi S Angewandte Chemie-International Edition 2026
Structures of the 26S proteasome in complex with the Hsp70 co-chaperone Bag1 reveal a mechanism for direct substrate transfer (Open Access) Maestro-López M, Cheng TC, (...), Sakata E Science Advances 2026
Models of the Human Heart for Biomedical Research: Opportunities and Challenges (Open Access) Streckfuss-Bömeke K, Zelarayán LC, (...), Kohl P Preprints 2026
Mechanism of human tRNA 3’CCA maturation (Open Access) Kuhle B, Krebs L, Bhatta A, Dennerlein S, Rehling P, Hillen HS bioRxiv 2026
Struktur der viralen Polymerase offenbart Einblicke in RNA-Synthese (Open Access) Bardtke A, Hillen HS BIOspektrum 2026
Future Optical Cochlear Implants Huet A Advancing Cochlear Implants 2026
Image modifications reduce differences in natural-image encoding by retinal ganglion cells between natural and optogenetic stimulation (Open Access) Ramakrishna V, Gollisch T bioRxiv 2026
A transition-prone brain state precedes spontaneous behavioral switching (Open Access) Wanken P, Edelman BJ, Behera L, Martinez de Paz JM, McCarthy PT, Macé E bioRxiv 2026
Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease (Open Access) Pradhan R, Petrovic Z, (...), Fischer A Advanced Science 2026
A correlative workflow for synaptic imaging by cryo-electron tomography (Open Access) Do TT, Siegert A, (...), Fernández-Busnadiego R Structure 2026
Dysferlin stabilizes membrane nanodomains of cardiomyocytes after myocardial infarction (Open Access) Wegener JB, Zühlke Y, (...), Brandenburg S Scientific Reports 2026
Myosin II-driven contractions of supporting cap cells promote sensory adaptation of Drosophila proprioceptors Guan C, Nishi K, Kreis CT, Bäumchen O, Göpfert MC, Schmidt CF Current Biology 2026
Spatial adaptation of primate retinal ganglion cells between artificial and natural stimuli (Open Access) Vystrčilová M, Sridhar S, (...), Ecker AS eNeuro 2026
Revisiting foundation models for cell instance segmentation (Open Access) Archit A, Pape C arXiv 2026
Early demyelination by off-target complement injury in a mouse model of neuromyelitis optica (Open Access) Kenet S, Herwerth M, (...), Misgeld T bioRxiv 2026
Neuroinflammatory profiles and cellular localization of TNF-α associated with chronic vanadium neurotoxicity Folarin R, Olopade F, (...), Olopade JO Metabolic Brain Disease 2026
Mitotic BLM functions are required to maintain genomic stability (Open Access) Hamann TE, Wieland A, (...), Räschle M Nucleic Acids Research 2026
Generation of marmoset monkeys with a non-mosaic disruption of the OTOF gene as a model of human deafness (Open Access) Kahland T, Lindenwald DL, (...), Moser T Nature Communications 2026
Arousal elicits a brain-wide hemodynamic wave independent of locus coeruleus noradrenergic tone (Open Access) Martinez de Paz JM, Mayer JL, (...), Macé E bioRxiv 2026
In‐situ‐Konstruktion von Imidazopyridinium‐Fluoreszenzlabels für Biokonjugationen (Open Access) Du D, Albert L, (...), Simeth NA Angewandte Chemie 2026
In Situ Construction of Imidazopyridinium Fluorescent Labels for Bioconjugation (Open Access) Du D, Albert L, (...), Simeth NA Angew Chem Int Ed Engl 2026
Mass spectrometric proteome profiling using a deep spectral library reveals homogenization of right and left atrial proteomes in persistent atrial fibrillation patients (Open Access) Liutkute A, Berrandou T, (...), Voigt N Cardiovascular Research 2026
Mechanisms and disease relevance of mitochondrial translation in humans Richter-Dennerlein R, Dopico XC, Rorbach J Nature Reviews Molecular Cell Biology 2026
Distributional Convergence of Empirical Entropic Optimal Transport and Statistical Applications (Open Access) Arenas-Velilla S, Munk A, Rodríguez L arXiv 2026
Self-propelled particles driven by light (Open Access) Fischer J, Jurado A, Betz T arXiv 2026
Labeling and imaging of neurons with a genetically encoded autonomous bioluminescence system (Open Access) Brinker T, Günther A, Kiszka KA, Rhee JS, Gregor C Scientific Reports 2026
Dense Embeddings from Self-Supervision and Foundation Models Improve Cell Linking Performance (Open Access) Dalinghaus C, Archit A, Pape C openreview.net 2026
The epitranscriptomic m6A RNA modification modulates the synapse in ageing and in a mouse model of synucleinopathy (Open Access) Chopra A, Xylaki M, (...), Outeiro TF npj Parkinsons Disease 2026
Membrane insertion of mitochondrial-encoded proteins regulates ribosome decoding speed (Open Access) Schöndorf T, Petrychenko V, (...), Rehling P Nature Structural & Molecular Biology 2026
A modular method for high-throughput measurement of ion channel currents in cardiac myocytes Seibertz F, Sobitov I, (...), Voigt N Nature Protocols 2026
A versatile nanobody platform for live and super-resolution imaging of synaptic vesicle dynamics and plasticity in rodent and human neurons (Open Access) Goel R, Jevdokimenko K, (...), Fornasiero EF Journal of Nanobiotechnology 2026
Quantifying 3D live-cell membrane dynamics using dynamic metal-induced energy transfer spectroscopy (dynaMIET) (Open Access) Gallea JI, Karedla N, (...), Chen T Science Advances 2026
Encoding performance of cortical neurons critically depends on their morphological and neurophysiological properties (Open Access) Revah O, Wolf F, Gutnick MJ, Neef A PLOS Biology 2026
TeraGram: A Structured Longitudinal Dataset of the Telegram Messenger (Open Access) Golovin A, Mohr SB, (...), Priesemann V arXiv 2026
Diverse mechanisms of translation arrest by a Clostridia ribosome stalling peptide CliM (Open Access) Yoshida M, Gersteuer F, (...), Chiba S Nature Communications 2026
Optogenetic cochlear stimulation evokes midbrain activity with near-physiological temporal fidelity (Open Access) Koert E, Götz J, Albrecht N, Vavakou A, Wolf BJ, Moser T bioRxiv 2026
Multichannel optical cochlear implants enable spectrally distinct auditory activity (Open Access) Albrecht N, Koert E, (...), Moser T bioRxiv 2026
The vacuolar tauopathy-associated mutation D395G confers redox sensitivity to p97/VCP (Open Access) Rout SR, Kulke M, (...), Sakata E bioRxiv 2026
Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies (Open Access) Sridhar S, Vystrčilová M, (...), Gollisch T PLOS Computational Biology 2026
FRMPD4, a causal gene for intellectual disability and epilepsy, is associated with X-linked non-syndromic hearing loss (Open Access) Liedtke D, Rak K, (...), Vona B medRxiv 2026
Learning Through Noise: Why Subliminal Learning Works and When It Fails (Open Access) Brockers VC, Ventzke RD, Neuhaus V, Hidalgo-Ogalde B, Priesemann V arXiv 2026
The PET tracer [11C]MODAG-005 targets alpha-synuclein aggregates in the brain Saw RS, Haas S, (...), Herfert K Science Translational Medicine 2026
Early Myelination Supports the Establishment of Consistent Handedness (Open Access) Moore S, Subramanian S, (...), de Hoz L Glia 2026
Stem-Cell–Derived Biologic Ventricular Assist Tissue in Heart Failure Zimmermann W, Ensminger S, (...), Friede T New England Journal of Medicine 2026
Digital material management for biomedical consortia at University Medical Center Göttingen (Open Access) Giese RM, Saldeitis K, (...), Kusch H Zenodo 2026
Mechanics of Pandemics (Open Access) Contreras S, Dönges P, (...), Priesemann V arXiv 2026
Toward Chromoselective Transformations in Biological Systems: Perspectives and Challenges (Open Access) Simeth NA Angewandte Chemie-International Edition 2026
Targeting intracellular cholesterol imbalance rescues sarcomere–ER contact site signaling and ER remodeling in dilated cardiomyopathy (Open Access) Ignatyeva N, Cheruiyot C, (...), Ebert A Signal Transduction and Targeted Therapy 2026
Artificial Intelligence for Discovery in Life Sciences (Open Access) Chanda S, Rizzoli SO, Shaib AH Bioconjugate Chemistry 2026
Blood-derived microRNA signatures associated with hippocampal structure and atrophy rate: findings from the Rhineland Study (Open Access) Melas K, Talevi V, (...), Breteler MMB Molecular Psychiatry 2026
The lncRNA Gm16685/MITA1 modulates inflammatory astrocyte reactivity through PCBP2 associated regulation of IKKβ signaling (Open Access) Fuchs U, Schroeder S, (...), Fischer A bioRxiv 2026
Inferring Cooperativity From Pooled Measurements (Open Access) Requadt R, Li H arXiv 2026
Loss of the lncRNA SOX1-OT promotes p53-dependent cell-cycle arrest in astrocytes (Open Access) Fuchs U, Schröder S, (...), Fischer A bioRxiv 2026
Anle138b ameliorates pathological phenotypes in mouse and cellular models of Huntington’s disease (Open Access) da Silva Padilha M, Koyuncu S, (...), Dudanova I EMBO Molecular Medicine 2026
Molecular mechanisms of E-Syt-mediated stress resistance (Open Access) Benitez-Fuente F, Collado J, (...), Fernández-Busnadiego R bioRxiv 2026
RBM20 variants disrupt Ca2+ handling and metabolism in dilated and non-compaction cardiomyopathy stem cell models (Open Access) Rebs S, Sedaghat-Hamedani F, (...), Streckfuss-Bömeke K Signal Transduction and Targeted Therapy 2026
Focal astrocyte loss reveals nuclear translocation during lesion repopulation (Open Access) Herwerth M, Wyss MT, (...), Weber B Nature Neuroscience 2026
Structure and dynamics of the Nipah virus RNA-dependent RNA polymerase (Open Access) Sala FA, Hillen HS Trends in Biochemical Sciences 2026
Distributed representations of chemosensory valence in a naïve vertebrate brain (Open Access) Jenkins B, Frank T bioRxiv 2026
Deep learning for interactive and automated inner retinal layer segmentation in OCT of patients with retinitis pigmentosa using limited training data (Open Access) Laurence D, Schilling M, Grimm N, Macé E, Bemme S, Pape C medRxiv 2026
LRRK2/LRRK1 interactions modulate Rab7 activity and inhibit lysosomal exocytosis (Open Access) Merghani M, Gerhardt E, Hesse M, Fahlbusch C, Böcker CA, Outeiro TF bioRxiv 2026
Correlative X-ray imaging and fluorescence microscopy (Open Access) Sinha M, Yu B, (...), Köster S bioRxiv 2026
Hierarchical multi-timescale structural dynamics of the disordered N-terminal of p53 (Open Access) Szöllősi D, Pratihar S, (...), Grubmüller H Nature Communications 2026
Systematic review and transcriptomic meta-analysis of environmental enrichment reveal core molecular programs of brain plasticity (Open Access) Kurowska M, Miozzo F, (...), Wilczyński B bioRxiv 2026
Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome (Open Access) Fell J, Pavez-Giani M, (...), Cyganek L Circulation 2026
SGLT2 inhibition improves sarcomere contractile dysfunction in human models of dilated cardiomyopathy (Open Access) Plota D, Saleem HN, (...), Ebert A Journal of Translational Medicine 2026
Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions (Open Access) Bloothooft M, Verbruggen B, Seibertz F, Van der Heyden MA, Voigt N, De Boer TP Journal of Pharmacological and Toxicological Methods 2026
Chamber-specific human iPSC-derived cardiomyocytes: Functional validation of atrial and ventricular models for predictive safety and translational research (Open Access) Sobitov I, Sharkova K, (...), Zimmermann W Journal of Pharmacological and Toxicological Methods 2026
“Heart-in-the-dish” models identify mechanisms of diastolic dysfunction Dittrich GM, Zimmermann W Cell Stem Cell 2026
ONE microscopy Shaib AH, Alawieh MM, Rizzoli SO Nature Protocols 2026
Adaptation of OXPHOS biogenesis to cellular requirements (Open Access) Dennerlein S, Rehling P Protein Science 2026
Dielectric Interfaces Reshape Dynamic Single-Molecule Optical Fingerprints in Nanoscopic Polymer Films (Open Access) Marx D, Malsbenden D, Gligonov I, Wöll D, Enderlein J, Nevskyi O ChemRxiv 2026
Molecular basis for a Ca2+ binding hierarchy in the EF-hand motifs of CaBP2 (Open Access) Motosugi R, Walinda E, (...), Sakata E Journal of Biological Chemistry 2026
Innervated human cardiac muscle model reveals sympathetic drivers of KCNH2-associated arrhythmias (Open Access) Schneider LV, Setya MG, (...), Zafeiriou M Nature Communications 2026
Guanosine 10 methylation by TRMT11–TRMT112 optimizes human mitochondrial tRNAs for efficient translation (Open Access) Petrosyan J, Yilmaz M, (...), Bohnsack KE Nucleic Acids Research 2026
Peroxiredoxin-6 protects against oxidative stress-mediated hypertrophic remodeling in JPH2-A399S knock-in mice (Open Access) Quinn CJ, Lahiri SK, (...), Wehrens XH IJC Heart & Vasculature 2026
In silico framework for benchmarking optogenetic hearing restoration (Open Access) Khurana L, Nejedly P, (...), Jablonski L Journal of Neural Engineering 2026
Signatures of Hebbian plasticity in the nanoscale morphodynamics of cortical spines (Open Access) Soltanipour M, Nagel A, Willig KI, Wolf F bioRxiv 2026
Bright monomeric fluorescent protein elite-niRFP704 for two-channel near-infrared STED nanoscopy (Open Access) Habenstein F, Jensen N, (...), Jakobs S Proceedings of the National Academy of Sciences of the United States of America 2026
Systematic Review and Transcriptomic Meta-analysis of Environmental Enrichment Reveal Core Molecular Programs of Brain Plasticity (Open Access) Kurowska M, Miozzo F, (...), Wilczyński B Molecular Neurobiology 2026
Distinct mitochondrial DNA single-nucleotide variant signatures in TOP3A-deficient cardiomyocytes (Open Access) Gaubert M, Alachram H, (...), Wollnik B bioRxiv 2026
Optimizing infectious disease mitigation under dynamic conditions (Open Access) Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V Proceedings of the National Academy of Sciences of the United States of America 2026
A microfluidics platform for studying ion and solute transport by isolated synaptic vesicles (Open Access) Upmanyu N, Olsthoorn L, (...), Jahn R Colloids and Surfaces B-Biointerfaces 2026
Desmin Mutations Disrupt Filament Elongation and Drive Polymorphic Aggregation (Open Access) Schween L, Burchert J, (...), Fabry B bioRxiv 2026
Nanobodies Equippedwith HaloTag Enable Scalable Fluorescence-LifetimeMultiplexing (Open Access) Albert L, Basak S, (...), Opazo F ACS Nano 2026
Gromov-Wasserstein Barycenter Surrogates: Statistical Methodology, Distributional Limits and Applications (Open Access) Steinkamp F, Rodríguez LA, Otte JV, Munk A arXiv 2026
All-optical closed-loop control of human cardiomyocyte networks exploiting holographic optogenetics (Open Access) Wendland R, Schmieder F, (...), Czarske JW Communications Engineering 2026
Nanobodies equipped with HaloTag variants enable rapid and straightforward one-step immunofluorescence lifetime multiplexing (Open Access) Albert L, Basak S, (...), Opazo F bioRxiv 2026
Multimodal quantitative MRI finds early brain changes in asymptomatic X-linked adrenoleukodystrophy (Open Access) Meier K, Sahoo P, (...), Gärtner J Brain Communications 2026
Moving against the odds with a cyclic active Brownian ratchet: current enhancement and reversal (Open Access) Spornhauer T, Mahault B, Zierenberg J arXiv 2026
Orthosteric and allosteric inhibition of the brain V-ATPase outside the alternating-access cycle (Open Access) Kosmidis E, Fokaeos M, (...), Stamou D Nature Communications 2026
Advances and Applications in Population Voltage Imaging Dorst M, Fuzik J, (...), Szücs GM European Journal of Neuroscience 2026
Arrhythmic events and genetic variants as drivers for Takotsubo Syndrome: a patient-specific atrial stem-cell model. (Open Access) Brand C, Zinke C, (...), Streckfuss-Bömeke K Signal transduction and targeted therapy 2026
Improving optogenetic control over Gi/o-coupled receptor signaling by optimized GIRK channel expression Mücher B, Garrido-Charles A, (...), Herlitze S Science Signaling 2026
Years-long stability of X10 expansion microscopy hydrogels (Open Access) Abbas E, Shaib AH, Hassan MA, Rizzoli SO Journal of Biological Engineering 2026
Dielectric Interfaces Reshape Dynamic Single-MoleculeOptical Fingerprints in Nanometer-Thick Polymer Films (Open Access) Marx D, Malsbenden D, Gligonov I, Wöll D, Enderlein J, Nevskyi O Nano Letters 2026
Correlative X-ray imaging and fluorescence microscopy in hydrated environments (Open Access) Sinha M, Yu B, (...), Köster S Journal of Synchrotron Radiation 2026
Wie Herzmuskelzellen Ionenkanäle dynamisch in Nanodomänen organisieren (Open Access) Kohl T, Tsukanov R, Lehnart SE BIOspektrum 2026
InsightRP2—An Interdisciplinary Approach Toward Therapy Development in RP2-Associated Retinopathy (Open Access) Bögershausen N, Yigit G, (...), Wollnik B Human Gene Therapy 2026
Lysosomal signaling pathways influence heart rhythm, and regulate atrial function Akerman E, Capel RA, (...), Burton RAB Cardiovascular Research 2026
AMPK reinforces mitochondrial metabolism and suppresses pathological remodeling in Complex V–deficient cardiomyocytes (Open Access) Palacios-Contreras E, der Brügge Ka, (...), Pavez-Giani MG bioRxiv 2026
Nx3 Is a Z-Disk Structural and Signaling Hub That Is Reduced in Heart Failure (Open Access) Linke WA, Kümper L, (...), Otaibi Y Circulation Research 2026
Structure of the human mitochondrial RNA degradosome reveals a distinct mode of helicase–nuclease coupling (Open Access) do Prado PFV, Sharma S, (...), Hillen HS bioRxiv 2026
CochleaNet: deep learning-based image analysis for cochlear connectomics and gene therapy (Open Access) Roos L, Diniz AM, (...), Pape C Molecular Therapy 2026
Multichannel optical cochlear implants enable spectrally distinct auditory activity (Open Access) Albrecht N, Koert E, (...), Moser T EMBO Molecular Medicine 2026
Blocks, Pins, and Heavy Metal: Optimized Sample Preparation for Volume EM of Myelin in Mouse Central Nervous System Ruhwedel T, Wrede C, Hegermann J, Steyer AM, Möbius W Methods in Molecular Biology 2026
Reliable and scalable hybrid extraction pipeline with selective human-in-the-loop assessment for clinical digital fingerprinting enabling real-time prediction in cardiology (Open Access) Eberhardt M, Hempel P, (...), Riedemann G European Heart Journal 2026
CochleaNet: deep learning-based image analysis for cochlear connectomics and gene therapy (Open Access) Roos L, Diniz AM, (...), Pape C bioRxiv 2025
Impaired Atrial Mitochondrial Calcium Handling in Patients With Atrial Fibrillation (Open Access) Pronto JRD, Mason FE, (...), Voigt N Circulation Research 2025
SynapseNet: Deep learning for automatic synapse reconstruction (Open Access) Muth S, Moschref F, (...), Pape C Molecular Biology of the Cell 2025
Charting the nanotopography of inner hair cell synapses using MINFLUX nanoscopy (Open Access) Kapoor R, Kim H, (...), Moser T Science Advances 2025
Visual objects refine head direction coding (Open Access) Siegenthaler D, Denny H, (...), Macé É Science 2025
Toward elucidating the mechanism of cochlear stimulation by infrared light Moser T, Roos L Proceedings of the National Academy of Sciences of the United States of America 2025
Improved optogenetic modification of the spiral ganglion neurons for future optical cochlear implants (Open Access) Thirumalai A, Henseler J, (...), Huet AT Theranostics 2025
CryoRhodopsins: A comprehensive characterization of a group of microbial rhodopsins from cold environments (Open Access) Lamm GHU, Marin E, (...), Kovalev K Science Advances 2025
Isotropic, aberration-corrected light sheet microscopy for rapid high-resolution imaging of cleared tissue (Open Access) Aakhte M, Müller GF, (...), Huisken J Nature Biotechnology 2025
Brain-derived synaptic vesicles have an intrinsic ability to sequester tubulin (Open Access) Mimoso T, Korobeinikov A, (...), Reshetniak S BMC Biology 2025
Redundancy Maximization as a Principle of Associative Memory Learning (Open Access) Blümel M, Schneider AC, (...), Priesemann V arXiv 2025
lncRNA 3222401L13Rik/ENSG00000272070 modulates microglial inflammatory programs in association with PU.1 (Open Access) Pradhan R, Sakib MS, (...), Fischer A bioRxiv 2025
Nuclear Alpha‐Synuclein: Mechanisms and Implications for Synucleinopathies Outeiro TF, Koss DJ Movement Disorders 2025
Continuous dynamics of cooperation and competition in social decision-making (Open Access) Lewen D, Ivanov V, (...), Kagan I Communications Psychology 2025
Testing paradox may explain increased observed prevalence of bacterial STIs among MSM on HIV PrEP: A modeling study (Open Access) Müller L, Mallick P, (...), Contreras S Proceedings of the National Academy of Sciences of the United States of America 2025
Single-cell spatial transcriptomic profiling defines a pathogenic inflammatory niche in chronic active multiple sclerosis lesions (Open Access) Feng R, Spieth L, (...), Simons M Immunity 2025
Leonardo: a toolset to correct sample-induced artifacts in light sheet microscopy images (Open Access) Liu Y, Müller GF, (...), Peng T bioRxiv 2025
The Myo2 adaptor Ldm1 and its receptor Ldo16 mediate actin-dependent lipid droplet motility (Open Access) Zhao X, Diep DTV, (...), Bohnert M Cell Reports 2025
Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses (Open Access) Vasili E, König A, (...), Outeiro TF npj Parkinsons Disease 2025
Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function (Open Access) Asadollahi R, Ahmad A, (...), Lipstein N Nature Genetics 2025
Probing the role of synaptic adhesion molecule RTN4RL2 in setting up cochlear connectivity (Open Access) Karagulyan N, Überegger M, (...), Bandtlow C eLife 2025
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy (Open Access) Schwenzer N, Tsukanov R, (...), Lehnart SE Journal of Molecular and Cellular Cardiology Plus 2025
Persistence of vestibular function in the absence of glutamatergic transmission from hair cells (Open Access) Mukhopadhyay M, Modgekar R, (...), Pangrsic T bioRxiv 2025
Peroxisome protein import deficiency causes heart failure in mouse and human (Open Access) Hofhuis J, Tiburcy M, (...), Thoms S bioRxiv 2025
Weak convergence of Bayes estimators under general loss functions (Open Access) Requadt R, Li H, Munk A arXiv 2025
Mapping complex optical light field distributions with single fluorescent molecules (Open Access) Marx D, Gligonov I, Malsbenden D, Wöll D, Nevskyi O, Enderlein J arXiv 2025
A versatile microfluidics platform for enhanced multi-target super-resolution microscopy (Open Access) Basak S, Chi-Vu K, (...), Tsukanov R bioRxiv 2025
Transient non-local interactions dominate the dynamics of measles virus NTAIL (Open Access) Otteson L, Nagy G, (...), Vaiana SM Communications Chemistry 2025
Structural remodeling of the mitochondrial protein biogenesis machinery under proteostatic stress (Open Access) Ehses K, López-Alonso JP, (...), Fernández-Busnadiego R bioRxiv 2025
Active intracellular mechanics – a key to cellular function and organization Eskandari MA, Fischer J, Veyret N, Marx D, Betz T Journal of Cell Science 2025
FASTKD5 processes mitochondrial pre-mRNAs at noncanonical cleavage sites (Open Access) Antonicka H, Vučković A, (...), Shoubridge E Nucleic Acids Research 2025
Ca2+-Triggered (de)ubiquitination Events in Synapses (Open Access) Ainatzi S, Kaufmann SV, (...), Urlaub H Molecular & Cellular Proteomics 2025
Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid–protein interaction sites by mass spectrometry (Open Access) Welp L, Wulf A, (...), Urlaub H Nucleic Acids Research 2025
Phosphoproteomic identification of Mos-MAPK targets in meiotic cell cycle and asymmetric oocyte divisions (Open Access) Avilov I, Horokhovskyi Y, (...), Lenart P bioRxiv 2025
Deregulation of m6A-RNA methylation impairs adaptive hypertrophic response and drives maladaptation via mTORC1-S6K1-hyperactivation and autophagy impairment Annamalai K, Dilliker S, (...), Toischer K Cell Communication and Signaling 2025
Research highlight: new and powerful approach to wide-field fluorescence lifetime imaging with single-molecule sensitivity (Open Access) Enderlein J eLight 2025
Fast scanning small angle X-ray scattering of hydrated biological cells (Open Access) Yu B, Sinha M, Da Silva RM, Rölleke U, Burghammer M, Köster S bioRxiv 2025
Uncovering the Complexity of Synucleinopathies: An Ongoing Tale Between Proteins and Lipids (Open Access) Flores‐León M, Outeiro TF Movement Disorders 2025
Unlocking microglia pyroptosis in a model of type I interferon-driven neuroinflammation: lessons from Rnaset2−/− mice (Open Access) Wendland K, Irsfeld M, (...), Kettwig M Cell Death & Disease 2025
Complement C4d Informs the Differential Diagnosis of Inflammatory Demyelinating CNS Diseases (Open Access) Landt C, Held F, (...), Nessler S Neurology-Neuroimmunology & Neuroinflammation 2025
BioimageAIpub: a toolbox for AI-ready bioimaging data publishing (Open Access) Dvoretskii S, Archit A, Pape C, Moore J, Nolden M arXiv 2025
Self-blinking dye restores efficient use of nanobodies in single-molecule localization microscopy (Open Access) Basak S, Inamdar K, (...), Opazo F bioRxiv 2025
MedicoSAM: Robust Improvement of SAM for Medical Imaging Archit A, Freckmann L, Pape C IEEE Transactions on Medical Imaging 2025
Transforming atrial fibrillation management by targeting comorbidities and reducing atrial fibrillation burden: the 10th AFNET/EHRA consensus conference (Open Access) Svennberg E, Merino JL, (...), Kirchhof P Europace 2025
Optimizing infectious disease mitigation under dynamic conditions (Open Access) Müller L, Sartori F, Dehning J, Eggl MF, Priesemann V arXiv 2025
Channelrhodopsin variants for high-rate optogenetic neurostimulation at low light intensities (Open Access) Roos L, Garrido-Charles A, (...), Mager T EMBO Molecular Medicine 2025
Correction to ‘FASTKD5 processes mitochondrial pre-mRNAs at noncanonical cleavage site’ (Open Access) Antonicka H, Vučković A, (...), Shoubridge E Nucleic Acids Research 2025
C 02-11 A Holistic Perspective: Investigating Electrophysiology and Contractility of atrial vs ventricular hiPSC-cardiomyocytes (Open Access) Dragicevic E, Seibertz F, (...), Fertig N Acta Physiologica 2025
Photoactivatable and photolabile pharmacophores: lessons learned from capsaicin (Open Access) Imse N, Rojas L, Gil Herrero C, Thallmair S, Rhee J, Simeth NA RSC Chemical Biology 2025
Structural basis for no retinal binding in flotillin-associated rhodopsins (Open Access) Kovalev K, Stetsenko A, (...), Guskov A Structure 2025
Adaptive Monotonicity Testing in Sublinear Time Li H, Liu Z, Munk A IEEE Transactions on Information Theory 2025
Super-resolution microscopy of mitochondrial mRNAs (Open Access) Stoldt S, Maass F, (...), Jakobs S Nature Communications 2025
Gating of hair cell Ca 2+ channels governs the activity of cochlear neurons (Open Access) Karagulyan N, Thirumalai A, (...), Moser T Science Advances 2025
Landscape of Target State Directed Processes in Living Systems (Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf F PRX Life 2025
In situ architecture of the human prohibitin complex (Open Access) Lange F, Ratz M, (...), Jakobs S Nature Cell Biology 2025
Autonomous bioluminescence emission from transgenic mice (Open Access) Kiszka KA, Dullin C, (...), Gregor C Science Advances 2025
Profiling the LAM Family of Contact Site Tethers Provides Insights into Their Regulation and Function (Open Access) Fenech EJ, Kupervaser M, (...), Schuldiner M Contact 2025
Power-law adaptation in the presynaptic vesicle cycle (Open Access) Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli SO, Priesemann V Communications Biology 2025
Super‐Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live Cells (Open Access) Wang D, Gallea JI, Kong D, Enderlein J, Chen T Angewandte Chemie-International Edition 2025
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Optimizing Electrical Field Stimulation Parameters Reveals the Maximum Contractile Function of Human Skeletal Muscle Microtissues Tiper Y, Xie Z, (...), Gilbert PM American Journal of Physiology-Cell Physiology 2025
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Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing (Open Access) Chen H, Cretu C, (...), Moser T bioRxiv 2025
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NeuID, a novel neuron-specific lncRNA, resolves a key epigenetic mechanism linking gene silencing to Alzheimer’s disease (Open Access) Pradhan R, Petrovic Z, (...), Fischer A bioRxiv 2025
The clinical drug candidate anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation (Open Access) Han M, Frieg B, (...), Griesinger C bioRxiv 2025
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The lincRNA Pantr1 is a FOXG1 target gene conferring site-specific chromatin binding of FOXG1 (Open Access) Gather F, Rauleac T, (...), Vogel T Nucleic Acids Research 2025
A feedback circuitry involving γ-actin, β-actin and nonmuscle myosin-2 A controls tight junction and apical cortex mechanics (Open Access) Maupérin M, Sun Y, (...), Citi S Nature Communications 2025
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Charge-Dependent Fluorescence Lifetime Modulation in a Plasmonic Nanocavity Chizhik AI, Sakhapov DI, Gregor I, Karedla N, Enderlein J Journal of Physical Chemistry Letters 2025
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Phosphoproteomic identification of Mos–MAPK targets in meiotic cell cycle and asymmetric oocyte divisions (Open Access) Avilov I, Horokhovskyi Y, (...), Lenart P Journal of Cell Biology 2025
Uncovering Dual Molecular Diagnoses in Families with Complex Phenotypes through Structural and Clinical Study of Novel COL4A6 Variants (Open Access) Owrang D, Rad A, (...), Vona B QJM-An International Journal of Medicine 2025
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Mutations in the Key Autophagy Tethering Factor EPG5 Link Neurodevelopmental and Neurodegenerative Disorders Including Early‐Onset Parkinsonism (Open Access) Dafsari HS, Deneubourg C, (...), Jungbluth H Annals of Neurology 2025
Anle138b binds predominantly to the central cavity in lipidic Aβ₄₀ fibrils and modulates fibril formation (Open Access) Han M, Frieg B, (...), Griesinger C Nature Communications 2025
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Navigating Data Management Plans: From Terminological Confusion to Practical Implementation (Open Access) Ketabi A, Kossen R, (...), Krefting D German Medical Science GMS Publishing House 2025
Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system (Open Access) Jablonski L, Harczos T, (...), Moser T Journal of Neural Engineering 2025
Structure and function of otoferlin, a synaptic protein of sensory hair cells essential for hearing (Open Access) Chen H, Cretu C, (...), Moser T Science Advances 2025
3D Computational Modeling of Defective Early Endosome Distribution in Human iPSC-Based Cardiomyopathy Models (Open Access) Saleem HN, Ignatyeva N, Stuut C, Jakobs S, Habeck M, Ebert A Cells 2024
Folate receptor α deficiency – Myelin‐sensitive MRI as a reliable biomarker to monitor the efficacy and long‐term outcome of a new therapeutic approach (Open Access) Dreha‐Kulaczewski S, Sahoo P, (...), Gärtner J Journal of Inherited Metabolic Disease 2024
H3 Acetylation-Induced Basal Progenitor Generation and Neocortex Expansion Depends on the Transcription Factor Pax6 (Open Access) Sokpor G, Kerimoglu C, (...), Tuoc T Biology-Basel 2024
Chemical synthesis of site-selective advanced glycation end products in α-synuclein and its fragments Bosbach C, Gatzemeier LM, (...), Outeiro TF Organic & Biomolecular Chemistry 2024
Single-nucleus transcriptomics reveals adrenergic and STAT3 signalling in paradoxical low-flow low-gradient-specific cardiomyocyte subclusters: implications for aortic stenosis pathogenesis and treatment Xu X, Tan X, (...), Hasenfuß G Cardiovascular Research 2024
Transient Non-local Interactions Dominate the Dynamics of Measles Virus N TAIL (Open Access) Otteson L, Nagy G, (...), Vaiana SM bioRxiv 2024
Power-law adaptation in the presynaptic vesicle cycle (Open Access) Mikulasch FA, Georgiev SV, Rudelt L, Rizzoli S, Priesemann V bioRxiv 2024
FASTKD5 processes mitochondrial pre-mRNAs at non-canonical cleavage sites (Open Access) Antonicka H, Weraarpachai W, Vučković A, Hillen HS, Shoubridge EA bioRxiv 2024
Polycystin-1 loss of function increases susceptibility to atrial fibrillation through impaired DNA damage response (Open Access) Hendrickson T, Abigail Giese A, (...), Altamirano F bioRxiv 2024
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Dysferlin Enables Tubular Membrane Proliferation in Cardiac Hypertrophy Paulke NJ, Fleischhacker C, (...), Brandenburg S Circulation Research 2024
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Multiplex Microscopy Assay for Assessment of Therapeutic and Serum Antibodies against Emerging Pathogens (Open Access) Sartingen N, Stürmer V, (...), Laketa V Viruses-Basel 2024
Probing the role of Nogo receptor homolog NgR2 in setting up cochlear connectivity (Open Access) Karagulyan N, Überegger M, (...), Bandtlow C bioRxiv 2024
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Local Water Content in Polymer Gels Measured With Super‐Resolved Fluorescence Lifetime Imaging Jana S, Nevskyi O, (...), Wöll D Angewandte Chemie-International Edition 2024
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Lead as a toxic environmental toxicant in models of synucleinopathies (Open Access) Shvachiy L, Amaro-Leal Â, Machado F, Rocha I, Geraldes V, Outeiro TF bioRxiv 2024
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Drosophila MIC10b can polymerize into cristae-shaping filaments (Open Access) Stephan T, Stoldt S, (...), Jakobs S Life Science Alliance 2024
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Characterizing ATP processing by the AAA+ protein p97 at the atomic level (Open Access) Shein M, Hitzenberger M, (...), Schütz AK Nature Chemistry 2024
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Global alignment and local curvature of microtubules in mouse fibroblasts are robust against perturbations of vimentin and actin (Open Access) Blob A, Ventzke D, (...), Köster S Soft Matter 2024
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Increased Autonomous Bioluminescence Emission from Mammalian Cells by Enhanced Cofactor Synthesis (Open Access) Brinker T, Gregor C Chemosensors 2024
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Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABAARs and cytosolic gephyrin aggregation (Open Access) Zeppillo T, Ali H, (...), Krueger-Burg D Communications Biology 2024
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Lead as an Environmental Toxicant in Models of Synucleinopathies (Open Access) Geraldes V, Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF Social Science Research Network 2024
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Optimistic Search: Change Point Estimation for Large-scale Data via Adaptive Logarithmic Queries (Open Access) Kovács S, Li H, Haubner L, Munk A, Bühlmann P Journal of Machine Learning Research 2024
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Chemical crosslinking extends and complements UV crosslinking in analysis of RNA/DNA nucleic acid–protein interaction sites by mass spectrometry (Open Access) Welp LM, Sachsenberg T, (...), Urlaub H bioRxiv 2024
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Molecular Dynamics Trajectories Exploring the Impact of Phosphorylation on the Physiological Form of Human alpha-Synuclein in Aqueous Solution (Open Access) de Bruyn E, Dorn A, (...), Carloni P Zenodo 2024
Characterization of transient and progressive pulmonary fibrosis by spatially correlated phase contrast microCT, classical histopathology and atomic force microscopy D’Amico L, Svetlove A, (...), Dullin C Computers in Biology and Medicine 2024
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Recording ten-fold larger IKr conductances with automated patch clamping using equimolar Cs+ solutions (Open Access) Bloothooft M, Verbruggen B, Seibertz F, Heyden MAGvd, Voigt N, de Boer TP Frontiers in Physiology 2024
Biallelic NAA60 variants with impaired n-terminal acetylation capacity cause autosomal recessive primary familial brain calcifications (Open Access) Chelban V, Aksnes H, (...), Houlden H Nature Communications 2024
mtDNA Analysis using Mitopore (Open Access) Dobner J, Nguyen T, (...), Rossi A Molecular Therapy-Methods & Clinical Development 2024
NanoPlex: a universal strategy for fluorescence microscopy multiplexing using nanobodies with erasable signals (Open Access) Mougios N, Cotroneo ER, (...), Opazo F bioRxiv 2024
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Adsorption of alpha-synuclein and inhibition of fibril formation by nanocellulose and gold-coated-nanocellulose (Open Access) Lamtar Mohammadi E, Keikha R, Outeiro TF, Jebali A Cellulose 2024
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Multiscale Quantile Regression with Local Error Control (Open Access) Liu Z, Li H arXiv 2024
Formation of memory assemblies through the DNA-sensing TLR9 pathway (Open Access) Jovasevic V, Wood EM, (...), Radulovic J Nature 2024
Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice (Open Access) Kaurani L, Islam MR, (...), Fischer A EMBO Journal 2024
Gene therapy for deafness: are we there now? (Open Access) Moser T, Chen H, Kusch K, Behr R, Vona B EMBO Molecular Medicine 2024
Gender-Specific Effects on the Cardiorespiratory System and Neurotoxicity of Intermittent and Permanent Low-Level Lead Exposures (Open Access) Shvachiy L, Amaro-Leal A, Machado F, Rocha I, Outeiro TF, Geraldes V Biomedicines 2024
Robust inference of cooperative behaviour of multiple ion channels in voltage-clamp recordings (Open Access) Requadt R, Fink M, Kubica P, Steinem C, Munk A, Li H arXiv 2024
METTL3-dependent m6A modification of PSEN1 mRNA regulates craniofacial development through the Wnt/β-catenin signaling pathway (Open Access) Ma L, Zhou X, (...), Pan Y Cell Death & Disease 2024
Structural basis of Integrator-dependent RNA polymerase II termination (Open Access) Fianu I, Ochmann M, (...), Cramer P Nature 2024
Complexin has a dual synaptic function as checkpoint protein in vesicle priming and as a promoter of vesicle fusion (Open Access) López-Murcia FJ, Lin K, (...), Taschenberger H Proceedings of the National Academy of Sciences of the United States of America 2024
Molecular basis of human nuclear and mitochondrial tRNA 3'-processing (Open Access) Bhatta A, Kuhle B, (...), Hillen H bioRxiv 2024
Super-resolution going viral: T4 virus particles as perfect nature-designed 3D-Bio-NanoRulers (Open Access) Gallea JI, Nevskyi O, (...), Enderlein J bioRxiv 2024
How Natural Enzymes and Synthetic Ribozymes Generate Methylated Nucleotides in RNA Höbartner C, Bohnsack KE, Bohnsack MT Annual Review of Biochemistry 2024
Computational functions of precisely balanced neuronal assemblies in an olfactory memory network (Open Access) Meissner-Bernard C, Jenkins B, (...), Frank T bioRxiv 2024
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway (Open Access) Oliveira da Silva MI, Santejo M, (...), Liz MA Cell Death & Disease 2024
Integrated machine learning and multimodal data fusion for patho-phenotypic feature recognition in iPSC models of dilated cardiomyopathy Wali R, Xu H, (...), Ebert A Biological Chemistry 2024
Insights into cochlear structure by innovative light sheet fluorescence microscopy (Open Access) Roos L, Aakthe M, (...), Moser T Laryngo-Rhino-Otologie 2024
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Myosin II actively regulates Drosophila proprioceptors (Open Access) Guan C, Nishi K, Kreis CT, Bäumchen O, Göpfert MC, Schmidt CF bioRxiv 2024
A role for astrocytic miR-129-5p in Frontotemporal Dementia (Open Access) Kaurani L, Pradhan R, (...), Fischer A bioRxiv 2024
Microtubules: highway to … arrhythmia? (Open Access) Liutkute A, Prosser BL, Voigt N Cardiovascular Research 2024
Cerebellar Ex Vivo Magnetic Resonance Imaging at its Feasibility Limit: Up to 77-Microns Isotropic Resolution using Low-Bandwidth Balanced Steady State Free Precession (LoBa-bSSFP) Sequences and 3T Standard Equipment (Open Access) Weigel M, Dechent P, (...), Granziera C bioRxiv 2024
Profiling the LAM family of contact site tethers provides insights into their regulation and function (Open Access) Fenech EJ, Kupervaser M, (...), Schuldiner M bioRxiv 2024
Click Chemistry with Cell-Permeable Fluorophores Expands the Choice of Bioorthogonal Markers for Two-Color Live-Cell STED Nanoscopy (Open Access) Gregor C, Grimm F, Rehman J, Wurm CA, Egner A Cells 2024
A subgroup of light-driven sodium pumps with an additional Schiff base counterion (Open Access) Podoliak E, Lamm GHU, (...), Kovalev K Nature Communications 2024
Variational calculus approach to Zernike polynomials with application to fluorescence correlation spectroscopy (Open Access) Gligonov I, Enderlein J bioRxiv 2024
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Basic Science in Movement Disorders: Fueling the Engine of Translation into Clinical Practice (Open Access) Outeiro TF, Kalia LV, (...), Svenningsson P Movement Disorders 2024
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Three-dimensional multi-target super-resolution microscopy of cells using Metal-Induced Energy Transfer and DNA-PAINT (Open Access) Oleksiievets N, Mougios N, (...), Tsukanov R bioRxiv 2024
Generation of a pluripotent stem cell line (UMGi270-A) and a corresponding CRISPR/Cas9 modified isogenic control (UMGi270-A-1) from a patient with sudden onset dilated cardiomyopathy harboring a FLNC p.R2187P mutation (Open Access) Maurer W, Rebs S, (...), Streckfuss-Bömeke K Stem Cell Research 2024
Label-free quantification of imaging features in the extracellular matrix of left and right-sided colon cancer tissues (Open Access) Arora B, Kulkarni A, (...), Ramos-Gomes F Scientific Reports 2024
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Unbiased complexome profiling and global proteomics analysis reveals mitochondrial impairment and potential changes at the intercalated disk in presymptomatic R14 Δ/+ mice hearts (Open Access) Foo B, Amedei H, (...), Lehnart SE bioRxiv 2024
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An aldehyde-crosslinking mitochondrial probe for STED imaging in fixed cells (Open Access) Chen J, Stephan T, (...), Chen Z Proceedings of the National Academy of Sciences of the United States of America 2024
Integrative Analysis of miRNA Expression Profiles Reveals Distinct and Common Molecular Mechanisms Underlying Broad Diagnostic Groups of Severe Mental Disorders (Open Access) Poschmann J, Solomon P, (...), Heilbronner U Researchsquare 2024
Single-particle Cryo-EM and molecular dynamics simulations: A perfect match (Open Access) Bock LV, Igaev M, Grubmüller H Current Opinion in Structural Biology 2024
Through the Haze: Unveiling the Link Between Smoking and Atrial Fibrillation Mason FE, Voigt N American Journal of Physiology-Heart and Circulatory Physiology 2024
Author Correction: Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling (Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LC Communications Biology 2024
CaV1.3 channel clusters characterized by live-cell and isolated plasma membrane nanoscopy (Open Access) Schwenzer N, Teiwes NK, (...), Steinem C Communications Biology 2024
The molecular machinery for maturation of primary mtDNA transcripts (Open Access) Vučković A, Freyer C, Wredenberg A, Hillen HS Human Molecular Genetics 2024
Coordinating mitochondrial translation with assembly of the OXPHOS complexes (Open Access) Kremer LS, Rehling P Human Molecular Genetics 2024
CDK7 kinase activity promotes RNA polymerase II promoter escape by facilitating initiation factor release (Open Access) Velychko T, Mohammad E, (...), Lidschreiber M Molecular Cell 2024
Metabolic remodelling in atrial fibrillation: manifestations, mechanisms and clinical implications Bode D, Pronto JRD, Schiattarella GG, Voigt N Nature Reviews Cardiology 2024
Characterizing intracellular mechanics via optical tweezers-based microrheology (Open Access) Vos BE, Muenker TM, Betz T Current Opinion in Cell Biology 2024
Catching up but still miles behind—a patient registry for otoferlin (Open Access) Vona B, Wollnik B, Strenzke N, Moser T Experimental & Molecular Medicine 2024
Effective exosomes reduction in hypercholesterinemic patients suffering from cardiovascular diseases by lipoprotein apheresis: Exosomes apheresis Schröder S, Epple R, Fischer A, Schettler VJJ Therapeutic Apheresis and Dialysis 2024
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system (Open Access) Raimi OG, Ojha H, (...), Muqit MMK Science Advances 2024
GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases (Open Access) Lesmann H, Hustinx A, (...), Hsieh T Researchsquare 2024
The maintenance of oocytes in the mammalian ovary involves extreme protein longevity (Open Access) Harasimov K, Gorry RL, (...), Schuh M Nature Cell Biology 2024
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS (Open Access) Chatterjee M, Özdemir S, (...), Schneider A Nature Medicine 2024
Autonomous bioluminescence emission from transgenic mice (Open Access) Kiszka KA, Dullin C, (...), Gregor C bioRxiv 2024
X-ray phase-contrast tomography of cells manipulated with an optical stretcher (Open Access) Burchert J, Frohn J, (...), Köster S Journal of Synchrotron Radiation 2024
Lysosomal signalling pathways influence heart rhythm, and regulate atrial function (Open Access) Capel RA, Akerman E, (...), Burton RAB bioRxiv 2024
Open Problem: Active Representation Learning (Open Access) Milosevic N, Müller G, Huisken J, Scherf N arXiv 2024
Targeting calpain-2-mediated junctophilin-2 cleavage delays heart failure progression following myocardial infarction Lahiri SK, Lu J, (...), Wehrens XH Journal of Molecular and Cellular Cardiology 2024
Lipidic folding pathway of α-Synuclein via a toxic oligomer (Open Access) Sant V, Matthes D, (...), Andreas LB Researchsquare 2024
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice (Open Access) Edelman BJ, Siegenthaler D, (...), Macé E PLOS Biology 2024
Impaired Intracellular Calcium Buffering Contributes to the Arrhythmogenic Substrate in Atrial Myocytes From Patients With Atrial Fibrillation Fakuade FE, Hubricht D, (...), Voigt N Circulation 2024
Establishment of a globally accessible registry for auditory synaptopathy DFNB9 (OTOF) (Open Access) Vona B, Wollnik B, Moser T, Strenzke N Zeitschrift für Audiologie-Audiological Acoustics 2024
Aging and neurodegeneration: From molecular mechanisms to therapeutic interventions (Open Access) Outeiro TF, Brocardo PS, Gelain DP Journal of Neurochemistry 2024
Structural insights into the regulation of RyR1 by S100A1 (Open Access) Weninger G, Miotto MC, (...), Marks AR Proceedings of the National Academy of Sciences of the United States of America 2024
Interfering with aggregated α-synuclein in advanced melanoma leads to a major upregulation of MHC class II proteins Fokken C, Silbern I, (...), Becker D Melanoma Research 2024
A roadmap for ribosome assembly in human mitochondria (Open Access) Lavdovskaia E, Hanitsch E, (...), Richter-Dennerlein R Nature Structural & Molecular Biology 2024
Neurofilament Light Chain Serum Levels Mirror Age and Disability in Secondary Progressive Multiple Sclerosis (Open Access) Husseini L, Jung J, (...), Weber MS Neurology-Neuroimmunology & Neuroinflammation 2024
Microlens arrays for multichannel laser-to-waveguide coupling Kunze K, Gossler C, Peters V, Keppeler D, Moser T, Schwarz UT Applied Optics 2024
Peripheral whole blood microRNA expression in relation to vascular function: a population-based study (Open Access) Talevi V, Melas K, (...), Breteler MM Journal of Translational Medicine 2024
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome (Open Access) Busley AV, Gutiérrez-Gutiérrez O, (...), Cyganek L Cell Reports 2024
Helical superstructures between amyloid and collagen in cardiac fibrils from a patient with AL amyloidosis (Open Access) Schulte T, Chaves-Sanjuan A, (...), Ricagno S Nature Communications 2024
Glycation of alpha-synuclein enhances aggregation and neuroinflammatory responses (Open Access) Vasili E, König A, (...), Outeiro TF bioRxiv 2024
PRDM16-DT: A Brain and Astrocyte-Specific lncRNA Implicated in Alzheimer’s Disease (Open Access) Schröder S, Fuchs U, (...), Fischer A bioRxiv 2024
Accessing activity and viscoelastic properties of artificial and living systems from passive measurement Muenker TM, Knotz G, Krüger M, Betz T Nature Materials 2024
Doubling the resolution of fluorescence-lifetime single-molecule localization microscopy with image scanning microscopy Radmacher N, Nevskyi O, (...), Enderlein J Nature Photonics 2024
Analyzing cross-talk between superimposed signals: Vector norm dependent hidden Markov models and applications to ion channels (Open Access) Jula Vanegas L, Eltzner B, Rudolf D, Dura M, Lehnart SE, Munk A Annals of Applied Statistics 2024
Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons (Open Access) Riemenschneider H, Guo Q, (...), Edbauer D EMBO Reports 2024
Optical measurement of glutamate release robustly reports short-term plasticity at a fast central synapse (Open Access) Hain PJH, Moser T Frontiers in Molecular Neuroscience 2024
CaBP1 and 2 enable sustained CaV1.3 calcium currents and synaptic transmission in inner hair cells (Open Access) Oestreicher D, Chepurwar S, (...), Pangrsic T eLife 2024
3D imaging of SARS-CoV-2 infected hamster lungs by X-ray phase contrast tomography enables drug testing (Open Access) Reichmann J, Sarrazin C, (...), Salditt T Scientific Reports 2024
Machine learning and advanced statistical analysis for fluorescence correlation spectroscopy Enderlein J Biophysical Journal 2024
Towards a biological diagnosis of PD (Open Access) Chopra A, Lang AE, Höglinger G, Outeiro TF Parkinsonism & Related Disorders 2024
Live cell Imaging of yeast cells expressing human PINK1-GFP and the TOM complex subunits v1 (Open Access) Ehses K protocols.io 2024
Establishing synthetic ribbon-type active zones in a heterologous expression system (Open Access) Kapoor R, Schwenzer N, Dresbach T, Lehnart SE, Moser T eLife 2024
Establishing synthetic ribbon-type active zones in a heterologous expression system (Open Access) Kapoor R, Schwenzer N, Dresbach T, Lehnart SE, Moser T bioRxiv 2024
Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina (Open Access) Zapp SJ, Khani MH, (...), Gollisch T bioRxiv 2024
mini-Complexome Profiling (mCP), an FDR-controlled workflow for global targeted detection of protein complexes (Open Access) Amedei H, Paul N, (...), Lenz C bioRxiv 2024
The molecular mechanism of on-demand sterol biosynthesis at organelle contact sites (Open Access) Zung N, Aravindan N, (...), Schuldiner M bioRxiv 2024
Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88 (Open Access) Lauer SM, Reepmeyer M, (...), Hoffmann R Nature Communications 2024
Circulating microRNAs are related to cognitive domains in the general population (Open Access) Melas K, Talevi V, (...), Breteler MM medRxiv 2024
Astrocytes adopt a progenitor-like migratory strategy for regeneration in adult brain (Open Access) Herwerth M, Wyss MT, (...), Weber B bioRxiv 2024
Autophagy preferentially degrades non-fibrillar polyQ aggregates (Open Access) Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling F Molecular Cell 2024
Stochastic tug-of-war among sarcomeres mediates cardiomyocyte response to environmental stiffness (Open Access) Haertter D, Hauke L, Driehorst T, Nishi K, Zimmermann W, Schmidt CF bioRxiv 2024
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver (Open Access) Aich A, Patrick G, Rehling P Zenodo 2024
Devising a framework of optogenetic coding in the auditory pathway: Insights from auditory midbrain recordings (Open Access) Michael M, Wolf BJ, Klinge-Strahl A, Jeschke M, Moser T, Dieter A Brain Stimulation 2023
The unique biomechanics of intermediate filaments – From single filaments to cells and tissues Rölleke U, Kumari P, Meyer R, Köster S Current Opinion in Cell Biology 2023
Tracking cell turnover in human brain using 15N-thymidine imaging mass spectrometry (Open Access) Roeder SS, Bonnin EA, (...), Huttner HB Frontiers in Neuroscience 2023
PrP meets alpha‐synuclein: Molecular mechanisms and implications for disease (Open Access) Vieira TCRG, Barros CA, Domingues R, Outeiro TF Journal of Neurochemistry 2023
High-resolution analysis of bound Ca2+ in neurons and synapses (Open Access) Bonnin EA, Golmohammadi A, Rehm R, Tetzlaff C, Rizzoli SO Life Science Alliance 2023
Fluorophore position of headgroup-labeled Gb3 glycosphingolipids in lipid bilayers Socrier L, Sharma A, (...), Steinem C Biophysical Journal 2023
FGFR1 variants contributed to families with tooth agenesis (Open Access) Yao S, Zhou X, (...), Pan Y Human Genomics 2023
Glucocerebrosidase mutations disrupt the lysosome and now the mitochondria (Open Access) Klein AD, Outeiro TF Nature Communications 2023
Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices (Open Access) Jentoft IM, Bäuerlein FJ, (...), Schuh M Cell 2023
Contractility measurements for cardiotoxicity screening with ventricular myocardial slices of pigs (Open Access) Shi R, Reichardt M, (...), Brügmann T Cardiovascular Research 2023
An NFATc1/SMAD3/cJUN complex restricted to SMAD4-deficient pancreatic cancer guides rational therapies Hasselluhn MC, Schlösser D, (...), Hessmann E Gastroenterology 2023
Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis (Open Access) Khan A, Markus MA, Svetlove A, Hülsmann S, Alves F, Dullin C Scientific Reports 2023
Activation of the integrated stress response rewires cardiac metabolism in Barth syndrome (Open Access) Kutschka I, Bertero E, (...), Dudek J Basic Research in Cardiology 2023
Structure of the transcribing RNA polymerase II–Elongin complex (Open Access) Chen Y, Kokic G, Dienemann C, Dybkov O, Urlaub H, Cramer P Nature Structural & Molecular Biology 2023
Bi-allelic ACBD6 variants lead to a neurodevelopmental syndrome with progressive and complex movement disorders (Open Access) Kaiyrzhanov R, Rad A, (...), Maroofian R Brain 2023
Approaching automation of multiple instance orchestration of the menoci web portal (Open Access) Freckmann L, Henke C, (...), Kusch H Bausteine FDM 2023
Efficient and sustained optogenetic control of nervous and cardiac systems (Open Access) Zerche M, Hunniford V, (...), Moser T bioRxiv 2023
Unraveling haplotype errors in the DFNA33 locus (Open Access) Vona B, Regele S, (...), Am Zehnhoff-Dinnesen AG Frontiers in Genetics 2023
Prediction mismatch responses arise as corrections of a predictive spiking code (Open Access) van Driel K, Rudelt L, Priesemann V, Mikulasch FA bioRxiv 2023
Tazarotene and Bexarotene Show Efficacy as In Vitro Therapeutic Agents in Multiple Sulfatase Deficiency (Open Access) Schlotawa L, Matysiak K, (...), Gärtner J Neuropediatrics 2023
Helical superstructures between amyloid and collagen VI in heart-derived fibrils from a patient with Light Chain Amyloidosis. (Open Access) Schulte T, Chaves-Sanjuan A, (...), Ricagno S Researchsquare 2023
A dual-targeted drug inhibits cardiac ryanodine receptor Ca2+ leak but activates SERCA2a Ca 2+ uptake (Open Access) Wegener JW, Mitronova GY, (...), Lehnart SE Life Science Alliance 2023
Ca2+ regulation of glutamate release from inner hair cells of hearing mice (Open Access) Jaime Tobón LM, Moser T Proceedings of the National Academy of Sciences of the United States of America 2023
Nedd4-2-dependent regulation of astrocytic Kir4.1 and Connexin43 controls neuronal network activity (Open Access) Altas B, Rhee H, (...), Kawabe H Journal of Cell Biology 2023
Evaluation of MR-safe bioptomes for MR-guided endomyocardial biopsy in minipigs: a potential radiation-free clinical approach (Open Access) Svetlove A, Ritter CO, (...), Unterberg-Buchwald C European Radiology Experimental 2023
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in <i>Bacillus subtilis in vitro</i> (Open Access) Wicke D, Neumann P, (...), Stülke J Nucleic Acids Research 2023
Developmental changes of the mitochondria in the murine anteroventral cochlear nucleus (Open Access) Hintze A, Lange F, (...), Wichmann C iScience 2023
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing (Open Access) Schreiber M, Zafeiriou M Stem Cell Research 2023
Ca2+-binding to the C2E domain of otoferlin is required for hair cell exocytosis and hearing (Open Access) Chen H, Monga M, (...), Moser T Protein & Cell 2023
Therapeutic efficacy of AAV-mediated restoration of PKP2 in arrhythmogenic cardiomyopathy (Open Access) Kyriakopoulou E, Versteeg D, (...), van Rooij E Nature Cardiovascular Research 2023
Protein nanobarcodes enable single-step multiplexed fluorescence imaging (Open Access) de Jong-Bolm D, Sadeghi M, (...), Rizzoli SO PLOS Biology 2023
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners (Open Access) Kanwal N, Krogh N, (...), Bohnsack M Nucleic Acids Research 2023
Characteristics, Prevalence, and Clinical Relevance of Juxtacortical Paramagnetic Rims in Patients With Multiple Sclerosis Galbusera R, Bahn E, (...), Granziera C Neurology 2023
Region-Specific Phosphorylation Determines Neuroligin-3 Localization to Excitatory versus Inhibitory Synapses Altas B, Tuffy LP, (...), Poulopoulos A Biological Psychiatry 2023
Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells (Open Access) Schreiber M, Zafeiriou M Stem Cell Research 2023
Protocol to develop force-generating human skeletal muscle organoids (Open Access) Shahriyari M, Rinn M, Hofemeier AD, Babych A, Zimmermann W, Tiburcy M STAR Protocols 2023
Proteomic analysis reveals the composition of glutamatergic organelles of auditory inner hair cell (Open Access) Cepeda AP, Ninov M, (...), Urlaub H Molecular & Cellular Proteomics 2023
Implications for neutrophils in cardiac arrhythmias Hegemann N, Barth L, Doering Y, Voigt N, Grune J American Journal of Physiology-Heart and Circulatory Physiology 2023
Structure and dynamics of human cardiac fibroblast nanotubes (Open Access) Schmid-Herbstritt S, Stief G, (...), Rog-Zielinska E bioRxiv 2023
The previously uncharacterized RnpM (YlxR) protein modulates the activity of ribonuclease P in Bacillus subtilis (Open Access) Wicke D, Neumann P, (...), Stülke J bioRxiv 2023
Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes (Open Access) Harasimov K, Uraji J, (...), Schuh M Nature Cell Biology 2023
Age-dependent structural reorganization of utricular ribbon synapses (Open Access) Michanski S, Henneck T, (...), Wichmann C Frontiers in Cell and Developmental Biology 2023
Association of early life stress and cognitive performance in patients with schizophrenia and healthy controls (Open Access) Senner F, Schneider-Axmann T, (...), Schulze TG Schizophrenia Research-Cognition 2023
Channelrhodopsin fluorescent tag replacement for clinical translation of optogenetic hearing restoration Zerche M, Wrobel C, Kusch K, Moser T, Mager T Molecular Therapy-Methods & Clinical Development 2023
Correction to: Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism (Open Access) Wohlfarter Y, Eidelpes R, (...), Keller MA Cellular and Molecular Life Sciences 2023
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons (Open Access) Weichard I, Taschenberger H, (...), Nerlich J Proceedings of the National Academy of Sciences of the United States of America 2023
Herzbeteiligung beo COVID-19: Makrophagen-getriebene Entzündung und Gefäßneubildung (Open Access) Werlein C, Ackermann M, (...), Jonigk D Pneumologie 2023
Homozygous loss-of-function variants in FILIP1 cause autosomal recessive arthrogryposis multiplex congenita with microcephaly (Open Access) Schnabel F, Schuler E, (...), Yigit G Human Genetics 2023
An Analytically Solvable Model of Firing Rate Heterogeneity in Balanced State Networks (Open Access) Schmidt A, Hiemeyer P, Wolf F arXiv 2023
Lyapunov spectra of chaotic recurrent neural networks (Open Access) Engelken R, Wolf F, Abbott LF Physical Review Research 2023
Bioinspired Membrane Interfaces: Controlling Actomyosin Architecture and Contractility (Open Access) Liebe NL, Mey I, (...), Steinem C ACS Applied Materials & Interfaces 2023
Adaptive minimax optimality in statistical inverse problems via SOLIT—Sharp Optimal Lepskiĭ-Inspired Tuning (Open Access) Li H, Werner F Inverse Problems 2023
Metal-Induced Energy Transfer (MIET) for Live-Cell Imaging with Fluorescent Proteins (Open Access) Hauke L, Isbaner S, (...), Enderlein J ACS Nano 2023
Minimax detection of localized signals in statistical inverse problems Pohlmann M, Werner F, Munk A Information and Inference-A Journal of the IMA 2023
NFATc1 Is a Central Mediator of EGFR-Induced ARID1A Chromatin Dissociation During Acinar Cell Reprogramming (Open Access) Zhang Z, Wang X, (...), Hessmann E Cellular and Molecular Gastroenterology and Hepatology 2023
Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins (Open Access) Schmidt A, Finegan T, (...), Peifer M Molecular Biology of the Cell 2023
miR-101a-3p Impairs Synaptic Plasticity and Contributes to Synucleinopathy (Open Access) Xylaki M, Paiva I, (...), Outeiro TF Journal of Parkinsons Disease 2023
Modular architecture facilitates noise-driven control of synchrony in neuronal networks (Open Access) Yamamoto H, Spitzner FP, (...), Soriano J Science Advances 2023
Roadmap for optical tweezers (Open Access) Volpe G, Maragò OM, (...), Swartzlander GA Journal of Physics-Photonics 2023
Simulation of Complex Biomolecular Systems: The Ribosome Challenge (Open Access) Bock LV, Gabrielli S, Kolář MH, Grubmüller H Annual Review of Biophysics 2023
Null and missense mutations of ERI1 cause a recessive phenotypic dichotomy in humans (Open Access) Guo L, Salian S, (...), Campeau PM American Journal of Human Genetics 2023
Statistical Analysis of Random Objects Via Metric Measure Laplacians Mordant G, Munk A SIAM Journal on Mathematics of Data Science 2023
The SARS-CoV-2 protein ORF3c is a mitochondrial modulator of innate immunity (Open Access) Stewart H, Lu Y, (...), Firth AE iScience 2023
The Ultrametric Gromov–Wasserstein Distance Mémoli F, Munk A, Wan Z, Weitkamp C Discrete & Computational Geometry 2023
Uncovering the Molecular Link Between Lead Toxicity and Parkinson's Disease Shvachiy L, Geraldes V, Outeiro TF Antioxidants & Redox Signaling 2023
Cryo-EM for Structure Determination of Mitochondrial Ribosome Samples Hillen HS Methods in Molecular Biology 2023
The role of structural vs cellular remodeling in arrhythmogenesis: personalized computer models of atrial fibrillation (Open Access) Pikunov AV, Syunyaev RA, (...), Efimov IR bioRxiv 2023
Visualization of deglutition and gastroesophageal reflux using real-time MRI: a standardized approach to image acquisition and assessment (Open Access) Biggemann L, Uhlig J, (...), Seif Amir Hosseini A Scientific Reports 2023
Defining the Riddle in Order to Solve It: There Is More Than One “Parkinson's Disease” (Open Access) Outeiro TF, Alcalay RN, (...), Ferreira JJ Movement Disorders 2023
The promise of optogenetic arrhythmia termination (Open Access) Bruegmann T, Sacconi L Journal of Internal Medicine 2023
Author Correction: Selective optogenetic control of Gq signaling using human Neuropsin (Open Access) Wagdi A, Malan D, (...), Bruegmann T Nature Communications 2023
Empirical Optimal Transport under Estimated Costs: Distributional Limits and Statistical Applications (Open Access) Hundrieser S, Mordant G, Weitkamp CA, Munk A arXiv 2023
Translation Factor Accelerating Peptide Bond Formation on the Ribosome: EF-P and eIF5A as Entropic Catalysts and a Potential Drug Targets (Open Access) Mudryi V, Peske F, Rodnina M BBA Advances 2023
Impact of the Euro 2020 championship on the spread of COVID-19 (Open Access) Dehning J, Mohr SB, (...), Priesemann V Nature Communications 2023
Structural insights into human co-transcriptional capping Garg G, Dienemann C, (...), Cramer P Molecular Cell 2023
Trafficking proteins show limited differences in mobility across different postsynaptic spines (Open Access) Mougios N, Opazo F, Rizzoli SO, Reshetniak S iScience 2023
Membrane-Bound Vimentin Filaments Reorganize and Elongate under Strain (Open Access) Nageswaran S, Haipeter J, Bodenschatz JFE, Meyer R, Köster S, Steinem C Biomacromolecules 2023
Single-cell transcriptomics reveal extracellular vesicles secretion with a cardiomyocyte proteostasis signature during pathological remodeling (Open Access) Schoger E, Bleckwedel F, (...), Zelarayán LC Communications Biology 2023
The long-loop recycling (LLR) of synaptic components as a question of economics (Open Access) Georgiev SV, Rizzoli SO Molecular and Cellular Neuroscience 2023
More than meets the eye in Parkinson’s disease and other synucleinopathies: from proteinopathy to lipidopathy (Open Access) Flores-Leon M, Outeiro TF Acta Neuropathologica 2023
Cholesterol-Induced Nanoscale Variations in the Thickness of Phospholipid Membranes (Open Access) Chen T, Ghosh A, Enderlein J Nano Letters 2023
Force generation in human blood platelets by filamentous actomyosin structures (Open Access) Zelená A, Blumberg J, (...), Köster S Biophysical Journal 2023
Towards Unbiased Fluorophore Counting in Superresolution Fluorescence Microscopy (Open Access) Laitenberger O, Aspelmeier T, Staudt T, Geisler C, Munk A, Egner A Nanomaterials 2023
Patient perspectives on the need for improved hearing rehabilitation: A qualitative survey study of German cochlear implant users (Open Access) Hunniford V, Kühler R, Wolf B, Keppeler D, Strenzke N, Moser T Frontiers in Neuroscience 2023
Graded optogenetic activation of the auditory pathway for hearing restoration (Open Access) Mittring A, Moser T, Huet A Brain Stimulation 2023
Beyond Motor Deficits: Environmental Enrichment Mitigates Huntington’s Disease Effects in YAC128 Mice (Open Access) Plácido E, Gomes Welter P, (...), Brocardo PS International Journal of Molecular Sciences 2023
LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome (Open Access) Busley AV, Gutiérrez-Gutiérrez Ó, (...), Cyganek L bioRxiv 2023
Synaptic activity is not required for establishing heterogeneity of inner hair cell ribbon synapses (Open Access) Karagulyan N, Moser T Frontiers in Molecular Neuroscience 2023
Natural stimuli drive concerted nonlinear responses in populations of retinal ganglion cells (Open Access) Karamanlis D, Khani MH, Schreyer HM, Zapp SJ, Mietsch M, Gollisch T bioRxiv 2023
Secreted-Frizzled-Related Protein 5 Modulates Calcium Handling in Human Ipsc-Cardiomyocytes (Open Access) Weber F, Klas S, (...), Cyganek L Social Science Research Network 2023
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease (Open Access) Brembati V, Faustini G, Longhena F, Outeiro TF, Bellucci A International Journal of Molecular Sciences 2023
Flotillin-Associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes (Open Access) Haro-Moreno JM, López-Pérez M, (...), Rodriguez-Valera F bioRxiv 2023
X-ray phase-contrast 3D virtual histology characterises complex tissue architecture in colorectal cancer (Open Access) Svetlove A, Griebel T, (...), Dullin C Frontiers in Gastroenterology 2023
Multimodal epigenetic changes and altered NEUROD1 chromatin binding in the mouse hippocampus underlie FOXG1 syndrome (Open Access) Akol I, Izzo A, (...), Vogel T Proceedings of the National Academy of Sciences of the United States of America 2023
A novel subgroup of light-driven sodium pumps with an additional Schiff base counterion (Open Access) Podoliak E, Lamm GHU, (...), Kovalev K bioRxiv 2023
An Animal Model for Chronic Meningeal Inflammation and Inflammatory Demyelination of the Cerebral Cortex (Open Access) Enz LS, Winkler A, (...), Schaeren-Wiemers N International Journal of Molecular Sciences 2023
Synapsin condensation controls synaptic vesicle sequestering and dynamics (Open Access) Hoffmann C, Rentsch J, (...), Milovanovic D Nature Communications 2023
CaBP1 and 2 enable sustained CaV 1.3 calcium currents and synaptic transmission in inner hair cells (Open Access) Oestreicher D, Chepurwar S, (...), Pangrsic T bioRxiv 2023
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system (Open Access) Saha I, Yuste-Checa P, (...), Hipp MS Nature Communications 2023
ATG9 resides on a unique population of small vesicles in presynaptic nerve terminals (Open Access) Binotti B, Ninov M, (...), Jahn R Autophagy 2023
Neuronal extracellular vesicles and associated microRNAs induce circuit connectivity downstream BDNF (Open Access) Antoniou A, Auderset L, (...), Schneider A Cell Reports 2023
Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina (Open Access) Krüppel S, Khani MH, (...), Gollisch T bioRxiv 2023
Drug screening identifies tazarotene and bexarotene as therapeutic agents in multiple sulfatase deficiency (Open Access) Schlotawa L, Tyka K, (...), Gärtner J EMBO Molecular Medicine 2023
HAV‐Peptides Attached to Colloidal Probes Faithfully Detect E‐Cadherins Displayed on Living Cells (Open Access) Toy S, Dietz J, (...), Janshoff A Chemistry-A European Journal 2023
Molecular engineering to enhance reactivity and selectivity in an ultrafast photoclick reaction Fu Y, Simeth NA, Toyoda R, Brilmayer R, Szymanski W, Feringa BL Angewandte Chemie-International Edition 2023
Lysinuric protein intolerance caused by a homozygous SLC7A7 deletion and presented with hyperferritinemia and osteoporosis in two siblings (Open Access) Kalay I, Aykut H, Caliskan Z, Yigit G, Wollnik B Molecular Genetics and Metabolism Reports 2023
Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism (Open Access) Grammatika Pavlidou N, Dobrev S, (...), Molina CE European Heart Journal 2023
Probing the role of the C2F domain of otoferlin (Open Access) Chen H, Fang Q, Benseler F, Brose N, Moser T Frontiers in Molecular Neuroscience 2023
Alpha-synuclein oligomers activate nuclear factor of activated T-cells (NFAT) modulating apoptosis and synaptic homeostasis (Open Access) Sant'Anna R, Robbs BK, (...), Foguel D bioRxiv 2023
Spliceosome malfunction causes neurodevelopmental disorders with overlapping features (Open Access) Li D, Wang Q, (...), Hakonarson H Journal of Clinical Investigation 2023
Conserved reduction of m6A RNA modifications during aging and neurodegeneration is linked to changes in synaptic transcripts (Open Access) Castro-Hernández R, Berulava T, (...), Fischer A Proceedings of the National Academy of Sciences of the United States of America 2023
The multifaceted mitochondrial OXA insertase (Open Access) Homberg B, Rehling P, Cruz-Zaragoza LD Trends in Cell Biology 2023
Mechanism of human PINK1 activation at the TOM complex in a reconstituted system (Open Access) Raimi OG, Ojha H, (...), Muqit MMK bioRxiv 2023
Defective COX1 expression in aging mice liver (Open Access) Witte S, Boshnakovska A, Özdemir M, Chowdhury A, Rehling P, Aich A Biology Open 2023
Observation of E-cadherin Adherens Junction Dynamics with Metal-Induced Energy Transfer Imaging and Spectroscopy (Open Access) Chen T, Karedla N, Enderlein J bioRxiv 2023
In vitro reconstitution of chromatin domains (Open Access) Quililan K, Oberbeckmann E, Cramer P, Oudelaar AM bioRxiv 2023
Intermittent Lead Exposure Induces Behavioral and Cardiovascular Alterations Associated with Neuroinflammation (Open Access) Shvachiy L, Amaro-Leal A, Outeiro TF, Rocha I, Geraldes V Cells 2023
SparseProp: Efficient Event-Based Simulation and Training of Sparse Recurrent Spiking Neural Networks (Open Access) Engelken R arXiv 2023
The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies (Open Access) Hoffmann J, Hanß S, (...), Nauck N Clinical Research in Cardiology 2023
Excitation Intensity-Dependent Quantum Yield of Semiconductor Nanocrystals (Open Access) Ghosh S, Ross U, (...), Chizhik AI Journal of Physical Chemistry Letters 2023
Impact of Phosphorylation on alpha-Synuclein Structural Determinants (Open Access) Dorn AE, de Bruyn E, (...), Carloni P bioRxiv 2023
A quantitative fluorescence‐based approach to study mitochondrial protein import (Open Access) Jain N, Gomkale R, Bernhard O, Rehling P, Cruz‐Zaragoza LD EMBO reports 2023
Mit Lichtstrahlen das Gehör wiederherstellen (Open Access) Moser T Zeitschrift für Audiologie-Audiological Acoustics 2023
Discrimination between cyclic nucleotides in a cyclic nucleotide-gated ion channel Pan Y, Pohjolainen E, (...), Scheuring S Nature Structural & Molecular Biology 2023
Yeast PIC-Mediator structure with RNA polymerase II C-terminal domain (Open Access) Schilbach S, Wang H, Dienemann C, Cramer P Proceedings of the National Academy of Sciences of the United States of America 2023
Electrophysiological and calcium-handling development during long-term culture of human-induced pluripotent stem cell-derived cardiomyocytes (Open Access) Seibertz F, Sutanto H, (...), Voigt N Basic Research in Cardiology 2023
Towards a Biological Definition of Parkinson’s Disease (Open Access) Höglinger GU, Adler CH, (...), Lang AE Preprints 2023
Anle138b interaction in α-synuclein aggregates by dynamic nuclear polarization NMR (Open Access) Dervişoğlu R, Antonschmidt L, (...), Andreas LB Methods 2023
Reverse-time analysis uncovers universality classes in directional biological dynamics (Open Access) Lenner N, Eule S, Großhans J, Wolf F arXiv 2023
Reverse-time analysis and boundary classification of directional biological dynamics with multiplicative noise (Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf F arXiv 2023
Fully-primed slowly-recovering vesicles mediate presynaptic LTP at neocortical neurons (Open Access) Weichard I, Taschenberger H, (...), Nerlich J bioRxiv 2023
C1q is increased in cerebrospinal fluid‐derived extracellular vesicles in Alzheimer's disease: A multi‐cohort proteomics and immuno‐assay validation study (Open Access) Chatterjee M, Özdemir S, (...), Schneider A Alzheimers & Dementia 2023
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against inflammatory demyelination (Open Access) Kapell H, Fazio L, (...), Schirmer L Journal of Clinical Investigation 2023
Chemical Synthesis of Alpha‐Synuclein Proteins via Solid‐Phase Peptide Synthesis and Native Chemical Ligation (Open Access) Gatzemeier LM, Meyer F, Diederichsen U, Outeiro TF Chemistry-A European Journal 2023
A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia (Open Access) Kaurani L, Islam MR, (...), Fischer A bioRxiv 2023
Bayesian MRI reconstruction with joint uncertainty estimation using diffusion models (Open Access) Luo G, Blumenthal M, Heide M, Uecker M Magnetic Resonance in Medicine 2023
A small-angle X-ray scattering study of red blood cells in continuous flow (Open Access) Burchert J, Graceffa R, Saldanha O, Burghammer M, Köster S Journal of Synchrotron Radiation 2023
IDH3γ functions as a redox switch regulating mitochondrial energy metabolism and contractility in the heart (Open Access) Nanadikar MS, Vergel Leon AM, (...), Katschinski DM Nature Communications 2023
Zelltypen aus menschlichen pluripotenten Zellen und deren Anwendung in Zelltherapien Zimmermann W, Ader M, (...), Tonn T Gen- und Zelltherapie 2.023 - Forschung, klinische Anwendung und Gesellschaft 2023
3d Virtual Histology Reveals Pathological Alterations of Cerebellar Granule Cells in Multiple Sclerosis (Open Access) Frost J, Schmitzer B, (...), Salditt T Neuroscience 2023
The Drosophila MIC10 orthologue has a propensity to polymerize into cristae-shaping filaments (Open Access) Stephan T, Stoldt S, (...), Jakobs S bioRxiv 2023
A Bright Surprise: Live‐Cell Labeling with Negatively Charged Fluorescent Probes based on Disulfonated Rhodamines and HaloTag (Open Access) Kim D, Stoldt S, Weber M, Jakobs S, Belov VN, Hell SW Chemistry-Methods 2023
Influence of phosphorylation on intermediate filaments (Open Access) Kraxner J, Köster S Biological Chemistry 2023
Signatures of heterogeneity in the statistical structure of target state aligned ensembles (Open Access) Lenner N, Häring M, Eule S, Großhans J, Wolf F arXiv 2023
Adaptive minimax optimality in statistical inverse problems via SOLIT -- Sharp Optimal Lepskii-Inspired Tuning (Open Access) Li H, Werner F arXiv 2023
Quantitative MRI by nonlinear inversion of the Bloch equations (Open Access) Scholand N, Wang X, Roeloffs V, Rosenzweig S, Uecker M Magnetic Resonance in Medicine 2023
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V (Open Access) Busley AV, Kleinsorge M, Cyganek L Stem Cell Research 2023
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V (Open Access) Busley AV, Cyganek L Stem Cell Research 2023
The genetic spectrum of congenital ocular motor apraxia type Cogan: an observational study, continued (Open Access) Schröder S, Yigit G, (...), Brockmann K Orphanet Journal of Rare Diseases 2023
Three-dimensional analysis of human pancreatic cancer specimens by phase-contrast based X-ray tomography – the next dimension of diagnosis (Open Access) Pinkert-Leetsch D, Frohn J, Ströbel P, Alves F, Salditt T, Missbach-Guentner J Cancer Imaging 2023
A metabolically controlled contact site between lipid droplets and vacuoles (Open Access) Diep DTV, Collado JF, (...), Bohnert M bioRxiv 2023
Vimentin intermediate filaments structure and mechanically support microtubules in cells (Open Access) Blob A, Ventzke D, (...), Köster S bioRxiv 2023
Protein transport along the presequence pathway Makki A, Rehling P Biological Chemistry 2023
Structural basis of catalytic activation in human splicing (Open Access) Schmitzová J, Cretu C, Dienemann C, Urlaub H, Pena V Nature 2023
Decoding and Recoding of mRNA Sequences by the Ribosome (Open Access) Rodnina MV Annual Review of Biophysics 2023
Human lung virtual histology by multi-scale x-ray phase-contrast computed tomography (Open Access) Reichmann J, Verleden SE, (...), Salditt T Physics in Medicine and Biology 2023
Fluorescence Spectroscopy in Planar Dielectric and Metallic Systems Chizhik AI, Ruhlandt D, Enderlein J Photonic Quantum Technologies 2023
In vitro and in vivo characterization of improved channelrhodopsin ChRmine variants for optogenetic activation of the auditory pathway Zerche M, Hunniford V, Witzke I, Wolf B, Mager T, Moser T Laryngo-Rhino-Otologie 2023
Characterization of novel channelrhodopsin variants for blue-light optogenetic activation of the auditory pathway Roos L, Garrido-Charles A, Wolf B, Kusch K, Mager T, Moser T Laryngo-Rhino-Otologie 2023
From emergency response to long-term management: the many faces of the endemic state of COVID-19 (Open Access) Contreras S, Iftekhar EN, Priesemann V Lancet Regional Health-Europe 2023
Cytochrome c oxidase biogenesis – from translation to early assembly of the core subunit COX1 (Open Access) Dennerlein S, Rehling P, Richter‐Dennerlein R FEBS Letters 2023
Quick Adaptive Ternary Segmentation: An Efficient Decoding Procedure For Hidden Markov Models (Open Access) Mösching A, Li H, Munk A arXiv 2023
N 2-methylguanosine modifications on human tRNAs and snRNA U6 are important for cell proliferation, protein translation and pre-mRNA splicing (Open Access) Wang C, Ulryck N, (...), Graille M Nucleic Acids Research 2023
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes Dai Y, Ignatyeva N, (...), Ebert A Circulation Research 2023
Investigating human lung tissue by propagation-based phase-contrast X-ray tomography (Open Access) Reichmann J, Verleden S, (...), Salditt T LEAPS Meets Life Sciences Conference (14.05.-19.05, Elba), Bioimaging 2023
ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts Rouvière JO, Salerno-Kochan A, (...), Jensen TH Molecular Cell 2023
Physiology of intracellular calcium buffering Eisner D, Neher E, Taschenberger H, Smith G Physiological Reviews 2023
Molecular and cellular evidence for the impact of a hypertrophic cardiomyopathy-associated RAF1 variant on the structure and function of contractile machinery in bioartificial cardiac tissues (Open Access) Nakhaei-Rad S, Haghighi F, (...), Ahmadian MR Communications Biology 2023
Convergence of Empirical Optimal Transport in Unbounded Settings (Open Access) Staudt T, Hundrieser S arXiv 2023
Myelin insulation as a risk factor for axonal degeneration in autoimmune demyelinating disease (Open Access) Schäffner E, Bosch-Queralt M, (...), Stassart RM Nature Neuroscience 2023
Targeting Biomolecular Condensation and Protein Aggregation against Cancer Silva JL, Foguel D, (...), de Oliveira GAP Chemical Reviews 2023
Mechanisms of inward transmembrane proton translocation Kovalev K, Tsybrov F, (...), Gordeliy V Nature Structural & Molecular Biology 2023
Is it all the RAGE? Defining the role of the receptor for advanced glycation end products in Parkinson's disease (Open Access) Gasparotto J, Somensi N, (...), Gelain DP Journal of Neurochemistry 2023
Translation termination in human mitochondria – substrate specificity of mitochondrial release factors (Open Access) Nadler F, Richter-Dennerlein R Biological Chemistry 2023
AI and protein structure and function in neurological disease: relevance to disease management Outeiro TF, Vieira TCRG Nature Reviews Neurology 2023
Combining a Tetracycline (Tet)-inducible gRNA system and CRISPRa for titratable and timely controlled enhancement of endogenous SHISA3 activation in human induced pluripotent stem cells (hiPSC) (Open Access) Priesmeier L, Schoger E, Cyganek L, Cecilia Zelarayán L Stem Cell Research 2023
Cryo-EM structures of lipidic fibrils of amyloid-β (1-40) (Open Access) Frieg B, Han M, (...), Schröder GF bioRxiv 2023
Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina Krüppel S, Khani MH, (...), Gollisch T Journal of Neuroscience 2023
Infomorphic networks: Locally learning neural networks derived from partial information decomposition (Open Access) Graetz M, Makkeh A, Schneider AC, Ehrlich DA, Priesemann V, Wibral M arXiv 2023
Hijacking of internal calcium dynamics by intracellularly residing rhodopsins (Open Access) Eria-Oliveira A, Folacci M, (...), Vivaudou M bioRxiv 2023
Flotillin-associated rhodopsin (FArhodopsin), a widespread paralog of proteorhodopsin in aquatic bacteria with streamlined genomes (Open Access) Haro-Moreno JM, López-Pérez M, (...), Rodriguez-Valera F mSystems 2023
Modulating Secondary Structure Motifs through Photo‐labile Peptide Staples (Open Access) Lāce I, Bazzi S, (...), Simeth NA Chembiochem 2023
Measuring sub-nanometer fluctuations at microsecond temporal resolution with metal-and graphene-induced energy transfer spectroscopy (Open Access) Chen T, Karedla N, Enderlein J bioRxiv 2023
Evaluation of Novel Enhancer Compounds in Gentamicin-Mediated Readthrough of Nonsense Mutations in Rett Syndrome (Open Access) Wong KM, Wegener E, Baradaran-Heravi A, Huppke B, Gärtner J, Huppke P International Journal of Molecular Sciences 2023
Vicious Twins: RyR2 Dysfunction and Structural Remodeling Voigt N, Seibertz F, Fakuade FE Circulation Research 2023
Effect of tissue fixation on the optical properties of structural components assessed by non-linear microscopy imaging (Open Access) Markus MA, Ferrari DP, Alves F, Ramos-Gomes F Biomedical Optics Express 2023
Metal-induced energy transfer (MIET) imaging of cell surface engineering with multivalent DNA nanobrushes (Open Access) Wang D, Liu B, (...), Chen T bioRxiv 2023
Piccolino is required for ribbon architecture at cochlear inner hair cell synapses and for hearing Michanski S, Kapoor R, (...), Wichmann C EMBO reports 2023
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto‐axonal target in late‐stage Parkinson's disease (Open Access) Warth Perez Arias CC, Silbern I, (...), Lingor P Journal of Neurochemistry 2023
Multiscale scanning with nuisance parameters (Open Access) König C, Munk A, Werner F arXiv 2023
Metabolic switch from fatty acid oxidation to glycolysis in knock-in mouse model of Barth syndrome (Open Access) Chowdhury A, Boshnakovska A, (...), Rehling P EMBO Molecular Medicine 2023
Modulation of translational decoding by m6A modification of mRNA (Open Access) Jain S, Koziej L, (...), Rodnina MV Nature Communications 2023
Glycation modulates superoxide dismutase 1 aggregation and toxicity in models of sporadic amyotrophic lateral sclerosis Monteiro Neto JR, Ribeiro GD, Magalhães RS, Follmer C, Outeiro TF, Eleutherio EC Biochimica et Biophysica Acta-Molecular Basis of Disease 2023
Structural conservation of antibiotic interaction with ribosomes Paternoga H, Crowe-McAuliffe C, (...), Wilson DN Nature Structural & Molecular Biology 2023
Aggregation and beyond: alpha-synuclein-based biomarkers in synucleinopathies Chopra A, Outeiro TF Brain 2023
A viral ADP-ribosyltransferase attaches RNA chains to host proteins (Open Access) Wolfram-Schauerte M, Pozhydaieva N, (...), Höfer K Nature 2023
The alpha-synuclein oligomers activate nuclear factor of activated T-cell (NFAT) modulating synaptic homeostasis and apoptosis (Open Access) Sant’Anna R, Robbs BK, (...), Foguel D Molecular Medicine 2023
DNA-Based Optical Sensors for Forces in Cytoskeletal Networks Jayachandran C, Ghosh A, (...), Schmidt CF ACS Applied Nano Materials 2023
Bioengineering of a human innervated cardiac muscle model (Open Access) Schneider LV, Bao G, (...), Zafeiriou M bioRxiv 2023
Ethanol-Induced Atrial Fibrillation Results From Late INa and Can Be Prevented by Ranolazine (Open Access) Mustroph J, Baier MJ, (...), Neef S Circulation 2023
A scalable clustering algorithm to approximate graph cuts (Open Access) Suchan L, Li H, Munk A arXiv 2023
Unravelling ATP processing by the AAA+ protein p97 at the atomic level (Open Access) Shein M, Hitzenberger M, (...), Schuetz A bioRxiv 2023
En route to sound coding strategy for optical cochlear implants (Open Access) Khurana L, Harczos T, Moser T, Jablonski L iScience 2023
Boosting of neural circuit chaos at the onset of collective oscillations (Open Access) Palmigiano A, Engelken R, Wolf F eLife 2023
N4-hydroxycytidine, the active compound of Molnupiravir, promotes SARS-CoV-2 mutagenesis and escape from a neutralizing nanobody (Open Access) Zibat A, Zhang X, (...), Dobbelstein M iScience 2023
Segment Anything for Microscopy (Open Access) Archit A, Nair S, (...), Pape C bioRxiv 2023
Intracellular mechanical fingerprint reveals cell type specific mechanical tuning (Open Access) Muenker TM, Vos BE, Betz T bioRxiv 2023
Doubling the resolution of single-molecule localization microscopy with image scanning microscopy (Open Access) Radmacher N, Nevskyi O, (...), Enderlein J bioRxiv 2023
Atrial fibrillation-associated electrical remodelling in human induced pluripotent stem cell-derived atrial cardiomyocytes: a novel pathway for antiarrhythmic therapy development (Open Access) Seibertz F, Rubio T, (...), Voigt N Cardiovascular Research 2023
Increased alpha-synuclein and neuroinflammation in the substantia nigra triggered by systemic inflammation are reversed by targeted inhibition of the receptor for advanced glycation end products (RAGE) Oppermann Peixoto D, Bittencourt RR, (...), Pens Gelain D Journal of Neurochemistry 2023
Low levels of circulating methylated IRX3 are related to worse outcome after transcatheter aortic valve implantation in patients with severe aortic stenosis (Open Access) Kanwischer L, Xu X, (...), Zeisberg EM Clinical Epigenetics 2023
Evaluating the association of biallelic OGDHL variants with significant phenotypic heterogeneity (Open Access) Lin S, Vona B, (...), Varshney GK Genome Medicine 2023
Baseline levels of miR-223-3p correlate with the effectiveness of electroconvulsive therapy in patients with major depression (Open Access) Kaurani L, Besse M, (...), Zilles-Wegner D Translational Psychiatry 2023
Fibroblast growth factor 9 (FGF9) mediated neurodegeneration: implications for progressive multiple sclerosis? (Open Access) Thümmler K, Wrzos C, (...), Linington C Neuropathology and Applied Neurobiology 2023
Phosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase Egbert JR, Silbern I, (...), Jaffe LA Biology of Reproduction 2023
4D‐Printable Photocrosslinkable Polyurethane‐Based Inks for Tissue Scaffold and Actuator Applications (Open Access) Goodarzi Hosseinabadi H, Biswas A, (...), Ionov L Small 2023
Control of intracellular pH and bicarbonate by CO2 diffusion into human sperm (Open Access) Grahn E, Kaufmann SV, (...), Kaupp U Nature Communications 2023
The COMBO window: A chronic cranial implant for multiscale circuit interrogation in mice (Open Access) Edelman B, Siegenthaler D, (...), Mace E bioRxiv 2023
Approaching automation of multiple instance orchestration of the menoci web portal (Open Access) Freckmann L, Henke C, (...), Kusch H German Medical Science GMS Publishing House 2023
Diversity matters - extending sound intensity coding by inner hair cells via heterogeneous synapses (Open Access) Moser T, Karagulyan N, Neef J, Jaime Tobón LM EMBO Journal 2023
Cardiac multiscale bioimaging: from nano- through micro- to mesoscales (Open Access) Tolstik E, Lehnart SE, Soeller C, Lorenz K, Sacconi L Trends in Biotechnology 2023
Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities (Open Access) Schaeper JJ, Liberman MC, Salditt T Journal of Medical Imaging 2023
GestaltMatcher Database - A global reference for facial phenotypic variability in rare human diseases (Open Access) Lesmann H, Hustinx A, (...), Hsieh TC medRxiv 2023
Single-Molecule Fluorescence Lifetime Imaging Using Wide-Field and Confocal-Laser Scanning Microscopy: A Comparative Analysis Oleksiievets N, Mathew C, (...), Enderlein J Nano Letters 2022
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind, placebo-controlled phase 1a trial (Open Access) Levin J, Sing N, (...), Giese A eBioMedicine 2022
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A Mathematical Model for Electrical Activity in Pig Atrial Tissue (Open Access) Peris-Yagüe V, Rubio T, Fakuade FE, Voigt N, Luther S, Majumder R Frontiers in Physiology 2022
Allosteric control of Ubp6 and the proteasome via a bidirectional switch (Open Access) Hung KYS, Klumpe S, (...), Finley D Nature Communications 2022
WARS1 and SARS1: two tRNA synthetases implicated in autosomal recessive microcephaly Bögershausen N, Krawczyk HE, (...), Wollnik B Human Mutation 2022
Simple model for encoding natural images by retinal ganglion cells with nonlinear spatial integration (Open Access) Liu JK, Karamanlis D, Gollisch T PLOS Computational Biology 2022
Statistical spatial analysis for cryo-electron tomography (Open Access) Martinez-Sanchez A, Baumeister W, Lučić V Computer Methods and Programs in Biomedicine 2022
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Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control (Open Access) Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R bioRxiv 2022
Model-based prediction of optogenetic sound encoding in the human cochlea by future optical cochlear implants (Open Access) Khurana L, Keppeler D, Jablonski L, Moser T Computational and Structural Biotechnology Journal 2022
Is there an unmet medical need for improved hearing restoration? Wolf BJ, Kusch K, (...), Moser T EMBO Molecular Medicine 2022
Biallelic variants in WARS1 cause a highly variable neurodevelopmental syndrome and implicate a critical exon for normal auditory function (Open Access) Lin S, Vona B, (...), Varshney GK Human Mutation 2022
Resolving the molecular architecture of the photoreceptor active zone with 3D-MINFLUX (Open Access) Grabner CP, Jansen I, (...), Moser T Science Advances 2022
Structure of a backtracked hexasomal intermediate of nucleosome transcription Farnung L, Ochmann M, Garg G, Vos SM, Cramer P Molecular Cell 2022
Role of Mitochondrial Nucleic Acid Sensing Pathways in Health and Patho-Physiology (Open Access) Chowdhury A, Witte S, Aich A Frontiers in Cell and Developmental Biology 2022
HAX1-dependent control of mitochondrial proteostasis governs neutrophil granulocyte differentiation (Open Access) Fan Y, Murgia M, (...), Klein C Journal of Clinical Investigation 2022
Stage-specific control of oligodendrocyte survival and morphogenesis by TDP-43 (Open Access) Heo D, Ling JP, (...), Bergles DE eLife 2022
Histone H1 binding to nucleosome arrays depends on linker DNA length and trajectory (Open Access) Dombrowski M, Engeholm M, Dienemann C, Dodonova S, Cramer P Nature Structural & Molecular Biology 2022
A mono- and intralink filter (mi-filter) to improve false-discovery rates in cross-linking mass spectrometry data (Open Access) Chen X, Sailer C, (...), Stengel F bioRxiv 2022
Non-Invasive Optical Motion Tracking Allows Monitoring of Respiratory Dynamics in Dystrophin-Deficient Mice (Open Access) Svetlove A, Albers J, (...), Dullin C Cells 2022
α-Synuclein Impacts on Intrinsic Neuronal Network Activity Through Reduced Levels of Cyclic AMP and Diminished Numbers of Active Presynaptic Terminals (Open Access) Leite K, Garg P, (...), Kügler S Frontiers in Molecular Neuroscience 2022
The 3D structure of lipidic fibrils of α-synuclein (Open Access) Frieg B, Antonschmidt L, (...), Schröder GF bioRxiv 2022
Glycation modulates glutamatergic signaling and exacerbates Parkinson’s disease-like phenotypes (Open Access) Chegão A, Guarda M, (...), Vicente Miranda H npj Parkinsons Disease 2022
Production of Recombinant Alpha-Synuclein: Still No Standardized Protocol in Sight (Open Access) Al-Azzani M, König A, Outeiro TF Biomolecules 2022
Using different geometries to modulate the cardiac fibroblast phenotype and the biomechanical properties of engineered connective tissues Santos GL, DeGrave AN, (...), Lutz S Biomaterials Advances 2022
Aging-Associated Changes in Cognition, Expression and Epigenetic Regulation of Chondroitin 6-Sulfotransferase Chst3 (Open Access) Baidoe-Ansah D, Sakib S, (...), Dityatev A Cells 2022
A review of protocols for human iPSC culture, cardiac differentiation, subtype-specification, maturation, and direct reprogramming (Open Access) Lyra-Leite DM, Gutiérrez-Gutiérrez O, Wang M, Zhou Y, Cyganek L, Burridge PW STAR Protocols 2022
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species Santos CC, Cardim-Pires TR, (...), Silva VDA Neurotoxicity Research 2022
Multiscale architecture: Mechanics of composite cytoskeletal networks (Open Access) Lorenz C, Köster S Biophysics Reviews 2022
Combined optical fluorescence microscopy andX-ray tomography reveals substructures in cellnuclei in 3D (Open Access) Wittmeier A, Bernhardt M, (...), Köster S Biomedical Optics Express 2022
DNA-PAINT MINFLUX nanoscopy (Open Access) Ostersehlt LM, Jans DC, (...), Jakobs S Nature Methods 2022
IGF-1 receptor regulates upward firing rate homeostasis via the mitochondrial calcium uniporter (Open Access) Katsenelson M, Shapira I, (...), Slutsky I Proceedings of the National Academy of Sciences of the United States of America 2022
Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 (Open Access) Gregor C Scientific Reports 2022
Direct proteomic and high-resolution microscopy biopsy analysis identifies distinct ventricular fates in severe aortic stenosis (Open Access) Brandenburg S, Otto L, (...), Lehnart SE Journal of Molecular and Cellular Cardiology 2022
Interdomain Dynamics via Paramagnetic NMR on the Highly Flexible Complex Calmodulin/Munc13-1 (Open Access) Karschin N, Becker S, Griesinger C Journal of the American Chemical Society 2022
The murine male reproductive organ at a glance: Three‐dimensional insights and virtual histology using label‐free light sheet microcopy (Open Access) Pinkert‐Leetsch D, Rost JU, Schmiedeknecht MUH, Stadelmann C, Alves F, Missbach‐Guentner J Andrology 2022
Ectosomes and exosomes modulate neuronal spontaneous activity Brás IC, Khani MH, (...), Outeiro TF Journal of Proteomics 2022
A modern automated patch-clamp approach for high throughput electrophysiology recordings in native cardiomyocytes (Open Access) Seibertz F, Rapedius M, (...), Voigt N Communications Biology 2022
Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II (Open Access) Rengachari S, Schilbach S, (...), Cramer P bioRxiv 2022
Quantitative Magnetic Resonance Imaging by Nonlinear Inversion of the Bloch Equations (Open Access) Scholand N, Wang X, Roeloffs V, Rosenzweig S, Uecker M arXiv 2022
A Reliable Approach for Revealing Molecular Targets in Secondary Ion Mass Spectrometry (Open Access) Li F, Fornasiero EF, Dankovich TM, Kluever V, Rizzoli SO International Journal of Molecular Sciences 2022
A Sequential Two-Step Priming Scheme Reproduces Diversity in Synaptic Strength and Short-Term Plasticity (Open Access) Lin K, Taschenberger H, Neher E Social Science Research Network 2022
A Variational View on Statistical Multiscale Estimation Haltmeier M, Li H, Munk A Annual Review of Statistics and Its Application 2022
Alpha-synuclein overexpression induces epigenomic dysregulation of glutamate signaling and locomotor pathways (Open Access) Schaffner SL, Wassouf Z, (...), Kobor MS Human Molecular Genetics 2022
Conserved reduction of m6A marks during aging and neurodegeneration is linked to altered translation of synaptic transcripts (Open Access) Castro-Hernández R, Berulava T, (...), Fischer A bioRxiv 2022
Doxorubicin induces cardiotoxicity in a pluripotent stem cell model of aggressive B cell lymphoma cancer patients (Open Access) Haupt LP, Rebs S, (...), Streckfuss-Bömeke K Basic Research in Cardiology 2022
Simultaneous assessment of lung morphology and respiratory motion in retrospectively gated in-vivo microCT of free breathing anesthetized mice (Open Access) Dullin C, Svetlove A, Zschüntzsch J, Alves F Scientific Reports 2022
Mitochondrien: wie die Gene im Kraftwerk der Zelle aktiviert werden (Open Access) Bhatta A, Hillen HS BIOspektrum 2022
MRI Reconstruction via Data Driven Markov Chain with Joint Uncertainty Estimation (Open Access) Luo G, Heide M, Uecker M arXiv 2022
Multi-color live-cell STED nanoscopy of mitochondria with a gentle inner membrane stain (Open Access) Liu T, Stephan T, (...), Chen Z bioRxiv 2022
Retinal Encoding of Natural Scenes Karamanlis D, Schreyer HM, Gollisch T Annual Review of Vision Science 2022
Synaptic transmission at the vestibular hair cells of amniotes Mukhopadhyay M, Pangrsic T Molecular and Cellular Neuroscience 2022
The Statistics of Circular Optimal Transport (Open Access) Hundrieser S, Klatt M, Munk A Forum for Interdisciplinary Mathematics 2022
Alteration of myocardial structure and function in RAF1-associated Noonan syndrome: Insights from cardiac disease modeling based on patient-derived iPSCs (Open Access) Nakhaei-Rad S, Bazgir F, (...), Ahmadian MR bioRxiv 2022
Whole genome sequencing for newborns—The devil is in the details (Open Access) Vona B Clinical and Translational Discovery 2022
GGPS1‐associated muscular dystrophy with and without hearing loss (Open Access) Kaiyrzhanov R, Perry L, (...), Maroofian R Annals of Clinical and Translational Neurology 2022
Functional and structural reverse myocardial remodeling following transcatheter aortic valve replacement: a prospective cardiovascular magnetic resonance study (Open Access) Lange T, Backhaus SJ, (...), Schuster A Journal of Cardiovascular Magnetic Resonance 2022
Huntingtin and Its Partner Huntingtin-Associated Protein 40: Structural and Functional Considerations in Health and Disease (Open Access) Seefelder M, Klein FA, Landwehrmeyer B, Fernández-Busnadiego R, Kochanek S Journal of Huntington's Disease 2022
Electrophysiological Characterization of Microbial Rhodopsins by Patch-Clamp Experiments Mager T Methods in Molecular Biology 2022
Imaging of Autonomous Bioluminescence Emission From Single Mammalian Cells Gregor C Methods in Molecular Biology 2022
A water-soluble manganese(II) octanediaoate/phenanthroline complex acts as an antioxidant and attenuates alpha-synuclein toxicity (Open Access) Queiroz DD, Ribeiro TdP, (...), Pereira MD Biochimica et Biophysica Acta-Molecular Basis of Disease 2022
Structure of the myenteric plexus in normal and diseased human ileum analyzed by X-ray virtual histology slices (Open Access) Veress B, Peruzzi N, (...), Ohlsson B World Journal of Gastroenterology 2022
Expansion microscopy at one nanometer resolution (Open Access) Shaib AH, Chouaib AA, (...), Rizzoli SO bioRxiv 2022
Cryo-electron tomography suggests tubulin chaperones form a subset of microtubule lumenal particles with a role in maintaining neuronal microtubules (Open Access) Chakraborty S, Martinez-Sanchez A, (...), Mahamid J bioRxiv 2022
Phosphorylation Determines Whether Neuroligin-3 is at Excitatory or Inhibitory Synapses in Different Regions of the Brain (Open Access) Altas B, Tuffy LP, (...), Poulopoulos A bioRxiv 2022
Functional Neuroligin-2-MDGA1 interactions differentially regulate synaptic GABA A Rs and cytosolic gephyrin aggregation (Open Access) Zeppillo T, Ali H, (...), Krueger-Burg D bioRxiv 2022
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Diversity of Ganglion Cell Responses to Saccade-like Image Shifts in the Primate Retina (Open Access) Nitsche S, Khani MH, (...), Gollisch T bioRxiv 2022
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Lost in promiscuity? An evolutionary and biochemical evaluation of HSD10 function in cardiolipin metabolism (Open Access) Wohlfarter Y, Eidelpes R, (...), Keller MA Cellular and Molecular Life Sciences 2022
The clinical drug candidate anle138b binds in a cavity of lipidic α-synuclein fibrils (Open Access) Antonschmidt L, Matthes D, (...), Andreas LB Nature Communications 2022
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Kantorovich–Rubinstein Distance and Barycenter for Finitely Supported Measures: Foundations and Algorithms (Open Access) Heinemann F, Klatt M, Munk A Applied Mathematics & Optimization 2022
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Kynurenine 3-Monooxygenase Interacts with Huntingtin at the Outer Mitochondrial Membrane (Open Access) Swaih AM, Breda C, (...), Giorgini F Biomedicines 2022
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Tackling the Dynamic Range Problem of Hearing: Diverse Hair Cell Synapses Enable Broad Neural Sound Intensity Coding (Open Access) Jaime Tobón LM, Moser T Social Science Research Network 2022
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Defined Engineered Human Myocardium for Disease Modeling, Drug Screening, and Heart Repair Tiburcy M, Meyer T, Satin P, Zimmermann W Methods in Molecular Biology 2022
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Electrically Controlling and Optically Observing the Membrane Potential of Supported Lipid Bilayers (Open Access) Yudovich S, Marzouqe A, (...), Weiss S Biophysical Journal 2022
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Calpain cleavage of Junctophilin-2 generates a spectrum of calcium-dependent cleavage products and DNA-rich NT1-fragment domains in cardiomyocytes (Open Access) Weninger G, Pochechueva T, (...), Lehnart SE Scientific Reports 2022
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Generation of bright autobioluminescent bacteria by chromosomal integration of the improved lux operon ilux2 Gregor C bioRxiv 2021
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Kantorovich-Rubinstein distance and barycenter for finitely supported measures: Foundations and Algorithms (Open Access) Heinemann F, Klatt M, Munk A arXiv 2021
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Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity (Open Access) Riera-Tur I, Schäfer T, (...), Dudanova I Life Science Alliance 2021
Electron Microscopic Reconstruction of Neural Circuitry in the Cochlea (Open Access) Hua Y, Ding X, (...), Wu H Cell Reports 2021
Mapping Activity-Dependent Quasi-stationary States of Mitochondrial Membranes with Graphene-Induced Energy Transfer Imaging Raja SO, Chizhik AI, Schmidt CF, Enderlein J, Ghosh A Nano Letters 2021
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Bucky Ball Is a Novel Zebrafish Vasa ATPase Activator (Open Access) Perera RP, Shaikhqasem A, (...), Dosch R Biomolecules 2021
Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner (Open Access) Sokpor G, Kerimoglu C, (...), Tuoc T Frontiers in Molecular Neuroscience 2021
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Integrative multi-omics analyses reveal multi-modal FOXG1 functions acting on epigenetic processes and in concert with NEUROD1 to regulate synaptogenesis in the mouse hippocampus (Open Access) Akol I, Heidrich S, (...), Vogel T bioRxiv 2021
A microRNA signature that correlates with cognition and is a target against cognitive decline (Open Access) Islam MR, Kaurani L, (...), Fischer A EMBO Molecular Medicine 2021
Human engineered skeletal muscle of hypaxial origin from pluripotent stem cells with advanced function and regenerative capacity (Open Access) Shahriyari M, Islam MR, (...), Tiburcy M bioRxiv 2021
LC-MS Based Platform Simplifies Access to Metabolomics for Peroxisomal Disorders (Open Access) Klemp HG, Kettwig M, Streit F, Gärtner J, Rosewich H, Krätzner R Metabolites 2021
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Cabp2-Gene Therapy Restores Inner Hair Cell Calcium Currents and Improves Hearing in a DFNB93 Mouse Model (Open Access) Oestreicher D, Picher MM, Rankovic V, Moser T, Pangrsic T Frontiers in Molecular Neuroscience 2021
Identification of Two Novel Peptides That Inhibit α-Synuclein Toxicity and Aggregation (Open Access) Popova B, Wang D, (...), Braus GH Frontiers in Molecular Neuroscience 2021
Small Molecule Fisetin Modulates Alpha–Synuclein Aggregation (Open Access) Rosado-Ramos R, Godinho-Pereira J, (...), Nunes dos Santos C Molecules 2021
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Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation (Open Access) Torres-Garcia L, Domingues JM, (...), Li J Researchsquare 2021
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Protein Signatures of NK Cell–Mediated Melanoma Killing Predict Response to Immunotherapies (Open Access) Cappello S, Sung H, (...), Bogeski I Cancer Research 2021
Impaired Exercise Tolerance in Repaired Tetralogy of Fallot Is Associated With Impaired Biventricular Contractile Reserve: An Exercise-Stress Real-Time Cardiovascular Magnetic Resonance Study (Open Access) Steinmetz M, Stümpfig T, (...), Paul T Circulation-Cardiovascular Imaging 2021
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Chalcone-Supported Cardiac Mesoderm Induction in Human Pluripotent Stem Cells for Heart Muscle Engineering (Open Access) Raad FS, Khan TA, (...), Zimmermann W ChemMedChem 2021
Cell programming to protect the ischemic heart and limb (Open Access) Brittan M, Zimmermann W Molecular Therapy 2021
Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation (Open Access) Schoger E, Zimmermann W, Cyganek L, Zelarayán LC Stem Cell Research 2021
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Novel Optics-Based Approaches for Cardiac Electrophysiology: A Review (Open Access) Müllenbroich MC, Kelly A, (...), Smith GL Frontiers in Physiology 2021
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Survey of germline variants in cancer‐associated genes in young adults with colorectal cancer Mikaeel RR, Young JP, (...), Price TJ Genes Chromosomes and Cancer 2021
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Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes (Open Access) Peper J, Kownatzki-Danger D, (...), Lehnart SE Circulation Research 2021
Transcriptionally active enhancers in human cancer cells (Open Access) Lidschreiber K, Jung LA, (...), Lidschreiber M Molecular Systems Biology 2021
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Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy (Open Access) Reinert M, Pacheu-Grau D, (...), Brockmann K Orphanet Journal of Rare Diseases 2021
Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast (Open Access) Zhang Y, De Laurentiis E, (...), Rospert S Nature Communications 2021
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Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex (Open Access) Ulmke PA, Sakib MS, (...), Tuoc T Stem Cell Reports 2021
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Statistical Molecule Counting in Super-Resolution Fluorescence Microscopy: Towards Quantitative Nanoscopy Staudt T, Aspelmeier T, Laitenberger O, Geisler C, Egner A, Munk A Statistical Science 2020
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Structure of complete Pol II–DSIF–PAF–SPT6 transcription complex reveals RTF1 allosteric activation Vos SM, Farnung L, Linden A, Urlaub H, Cramer P Nature Structural & Molecular Biology 2020
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Dual-Color Metal-Induced Energy Transfer (MIET) Imaging for Three-Dimensional Reconstruction of Nuclear Envelope Architecture Chizhik AI, Chizhik AM, (...), Enderlein J Methods in Molecular Biology 2020
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Developmental GABA polarity switch and neuronal plasticity in Bioengineered Neuronal Organoids (Open Access) Zafeiriou M, Bao G, (...), Zimmermann W Nature Communications 2020
Structural Biology of RNA Polymerase II Transcription: 20 Years On Osman S, Cramer P Annual Review of Cell and Developmental Biology 2020
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Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Seibertz F, Reynolds M, Voigt N Journal of Visualized Experiments 2020
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Randomised Wasserstein Barycenter Computation: Resampling with Statistical Guarantees (Open Access) Heinemann F, Munk A, Zemel Y arXiv 2020
Structural basis of nucleosome transcription mediated by Chd1 and FACT (Open Access) Farnung L, Ochmann M, Engeholm M, Cramer P bioRxiv 2020
Cellular and mitochondrial mechanisms of atrial fibrillation (Open Access) Mason FE, Pronto JRD, Alhussini K, Maack C, Voigt N Basic Research in Cardiology 2020
The Coding And Small-Non-Coding Hippocampal Synaptic RNAome (Open Access) Epple R, Krüger D, (...), Fischer A bioRxiv 2020
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Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity (Open Access) Medina L, González-Lizárraga F, (...), Socias SB bioRxiv 2020
CG‐SENSE revisited: Results from the first ISMRM reproducibility challenge (Open Access) Maier O, Baete SH, (...), Knoll F Magnetic Resonance in Medicine 2020
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R (Open Access) Dankovich TM, Kaushik R, (...), Rizzoli SO bioRxiv 2020
Distinct insulin granule subpopulations implicated in the secretory pathology of diabetes types 1 and 2 (Open Access) Kreutzberger AJ, Kiessling V, (...), Tamm LK eLife 2020
Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo (Open Access) Dominguez-Meijide A, Parrales V, (...), Outeiro TF bioRxiv 2020
Conformational dynamics of a G protein–coupled receptor helix 8 in lipid membranes (Open Access) Dijkman PM, Muñoz-García JC, (...), Watts A Science Advances 2020
An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding (Open Access) Bartsch A, Ives C, (...), Llabrés S bioRxiv 2020
Isolation of High Quality Murine Atrial and Ventricular Myocytes for Simultaneous Measurements of Ca2+ Transients and L-Type Calcium Current Tomsits P, Schüttler D, Kääb S, Clauss S, Voigt N Journal of Visualized Experiments 2020
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Heterogeneous Idealization of Ion Channel Recordings – Open Channel Noise (Open Access) Pein F, Bartsch A, Steinem C, Munk A IEEE Transactions on NanoBioscience 2020
Time-resolved MIET measurements of blood platelet spreading and adhesion (Open Access) Zelená A, Isbaner S, (...), Köster S Nanoscale 2020
X-Ray Structural Analysis of Single Adult Cardiomyocytes: Tomographic Imaging and Microdiffraction (Open Access) Reichardt M, Neuhaus C, Nicolas J, Bernhardt M, Toischer K, Salditt T Biophysical Journal 2020
Quantitative Synaptic Biology: A Perspective on Techniques, Numbers and Expectations (Open Access) Reshetniak S, Fernández-Busnadiego R, Müller M, Rizzoli SO, Tetzlaff C International Journal of Molecular Sciences 2020
Stable but not rigid: Long-term in vivo STED nanoscopy uncovers extensive remodeling of stable spines and indicates multiple drivers of structural plasticity (Open Access) Steffens H, Mott AC, (...), Willig KI bioRxiv 2020
Model‐based reconstruction for simultaneous multi‐slice mapping using single‐shot inversion‐recovery radial FLASH (Open Access) Wang X, Rosenzweig S, Scholand N, Holme HCM, Uecker M Magnetic Resonance in Medicine 2020
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Multiple Haplotype Reconstruction from Allele Frequency Data (Open Access) Pelizzola M, Behr M, Li H, Munk A, Futschik A bioRxiv 2020
Premature aging disorders: A clinical and genetic compendium (Open Access) Schnabel F, Kornak U, Wollnik B Clinical Genetics 2020
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Parental genome unification is highly erroneous in mammalian embryos (Open Access) Cavazza T, Politi AZ, (...), Schuh M bioRxiv 2020
Bioprospection of Natural Sources of Polyphenols with Therapeutic Potential for Redox-Related Diseases (Open Access) Menezes R, Foito A, (...), Santos CN Antioxidants 2020
Emission States Variation of Single Graphene Quantum Dots Ghosh S, Oleksiievets N, Enderlein J, Chizhik AI Journal of Physical Chemistry Letters 2020
Presynaptic Physiology of Cochlear Inner Hair Cells Moser T The Senses: A Comprehensive Reference 2020
3D virtual pathohistology of lung tissue from Covid-19 patients based on phase contrast X-ray tomography (Open Access) Eckermann M, Frohn J, (...), Salditt T eLife 2020
The Role of Alpha-Synuclein and Other Parkinson’s Genes in Neurodevelopmental and Neurodegenerative Disorders (Open Access) Morato Torres CA, Wassouf Z, Zafar F, Sastre D, Outeiro TF, Schüle B International Journal of Molecular Sciences 2020
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Local translation in synaptic mitochondria influences synaptic transmission (Open Access) Yousefi R, Fornasiero EF, (...), Pacheu-Grau D bioRxiv 2020
Three-dimensional beating dynamics of Chlamydomonas flagella (Open Access) Mojiri S, Isbaner S, (...), Enderlein J bioRxiv 2020
Novel Secondary Ion Mass Spectrometry Methods for the Examination of Metabolic Effects at the Cellular and Subcellular Levels (Open Access) Bonnin EA, Rizzoli SO Frontiers in Behavioral Neuroscience 2020
Minimax estimation in linear models with unknown design over finite alphabets (Open Access) Behr M, Munk A arXiv 2020
Gromov-Wasserstein Distance based Object Matching: Asymptotic Inference (Open Access) Weitkamp CA, Proksch K, Tameling C, Munk A arXiv 2020
Nucleosome-CHD4 chromatin remodeler structure maps human disease mutations (Open Access) Farnung L, Ochmann M, Cramer P eLife 2020
Bi-allelic missense disease-causing variants in RPL3L associate neonatal dilated cardiomyopathy with muscle-specific ribosome biogenesis (Open Access) Ganapathi M, Argyriou L, (...), Wollnik B Human Genetics 2020
Fluorescence polarization filtering for accurate single molecule localization (Open Access) Nevskyi O, Tsukanov R, Gregor I, Karedla N, Enderlein J APL Photonics 2020
Editorial commentary: Challenges to heart repair with pluripotent stem cell-derived cardiomyocytes Zimmermann W Trends in Cardiovascular Medicine 2020
Multi-particle cryo-EM refinement with M visualizes ribosome-antibiotic complex at 3.7 Å inside cells (Open Access) Tegunov D, Xue L, Dienemann C, Cramer P, Mahamid J bioRxiv 2020
Generation of Engineered Human Myocardium in a Multi-well Format (Open Access) Tiburcy M, Meyer T, Liaw NY, Zimmermann W STAR Protocols 2020
Empirical Regularized Optimal Transport: Statistical Theory and Applications (Open Access) Klatt M, Tameling C, Munk A SIAM Journal on Mathematics of Data Science 2020
NETT: solving inverse problems with deep neural networks (Open Access) Li H, Schwab J, Antholzer S, Haltmeier M Inverse Problems 2020
Hearing restoration by a low-weight power-efficient multichannel optogenetic cochlear implant system (Open Access) Jablonski L, Harczos T, (...), Moser T bioRxiv 2020
19th Annual Meeting of the Safety Pharmacology Society: regulatory and safety perspectives for advanced therapy medicinal products (cellular and gene therapy products) Cavero I, Seimetz D, Koziel D, Zimmermann W, Holzgrefe HH Expert Opinion on Drug Safety 2020
Impact of myocardial fibrosis on left ventricular remodelling, recovery, and outcome after transcatheter aortic valve implantation in different haemodynamic subtypes of severe aortic stenosis (Open Access) Puls M, Beuthner BE, (...), Hasenfuß G European Heart Journal 2020
Tomographic STED microscopy (Open Access) Krüger J, Keller-Findeisen J, Geisler C, Egner A Biomedical Optics Express 2020
De novo mutations in FBRSL1 cause a novel recognizable malformation and intellectual disability syndrome (Open Access) Ufartes R, Berger H, (...), Pauli S Human Genetics 2020
Circumvention of common labelling artefacts using secondary nanobodies (Open Access) Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F Nanoscale 2020
Vesicle adhesion in the electrostatic strong-coupling regime studied by time-resolved small-angle X-ray scattering (Open Access) Komorowski K, Schaeper J, (...), Salditt T Soft Matter 2020
Testing for dependence on tree structures (Open Access) Behr M, Ansari MA, Munk A, Holmes C Proceedings of the National Academy of Sciences of the United States of America 2020
White matter integrity requires continuous myelin synthesis at the inner tongue (Open Access) Meschkat M, Steyer AM, (...), Möbius W bioRxiv 2020
A Cross-linking Mass Spectrometry Approach Defines Protein Interactions in Yeast Mitochondria (Open Access) Linden A, Deckers M, (...), Urlaub H Molecular & Cellular Proteomics 2020
Towards the optical cochlear implant: optogenetic approaches for hearing restoration (Open Access) Dieter A, Keppeler D, Moser T EMBO Molecular Medicine 2020
Human RAD50 deficiency: Confirmation of a distinctive phenotype (Open Access) Ragamin A, Yigit G, (...), Mancini GMS American Journal of Medical Genetics Part A 2020
Multi-scale X-ray phase-contrast tomography of murine heart tissue (Open Access) Reichardt M, Frohn J, Khan A, Alves F, Salditt T Biomedical Optics Express 2020
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome Wagner FR, Dienemann C, (...), Cramer P Nature 2020
Fiber orientation in a whole mouse heart reconstructed by laboratory phase-contrast micro-CT (Open Access) Reichardt M, Töpperwien M, Khan A, Alves F, Salditt T Journal of Medical Imaging 2020
Seeded Binary Segmentation: A general methodology for fast and optimal change point detection (Open Access) Kovács S, Li H, Bühlmann P, Munk A arXiv 2020
Preclinical evidence for the therapeutic value of TBX5 normalization in arrhythmia control (Open Access) Rathjens FS, Blenkle A, (...), Zafeiriou M Cardiovascular Research 2020
JM-20 protects against 6-hydroxydopamine-induced neurotoxicity in models of Parkinson’s disease: Mitochondrial protection and antioxidant properties Fonseca-Fonseca LA, da Silva VDA, (...), Núñez-Figueredo Y Neurotoxicology 2020
Live-cell STED microscopy of mitochondrial cristae (Open Access) Stephan T, Roesch A, Riedel D, Jakobs S bioRxiv 2019
Live-cell STED nanoscopy of mitochondrial cristae (Open Access) Stephan T, Roesch A, Riedel D, Jakobs S Scientific Reports 2019
Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity Schaefer T, Riera-Tur I, (...), Dudanova I bioRxiv 2019
Macromolecular and electrical coupling between inner hair cells in the rodent cochlea (Open Access) Jean P, Anttonen T, (...), Moser T bioRxiv 2019
The recurrent postzygotic pathogenic variant p.Glu47Lys in RHOA causes a novel recognizable neuroectodermal phenotype (Open Access) Yigit G, Saida K, (...), Altmüller J Human Mutation 2019
Changes in m6A RNA methylation contribute to heart failure progression by modulating translation Berulava T, Buchholz E, (...), Toischer K European Journal of Heart Failure 2019
Metal-induced energy transfer (Open Access) Gregor I, Chizhik A, Karedla N, Enderlein J Nanophotonics 2019
MITRAC15/COA1 promotes mitochondrial translation in a ND2 ribosome–nascent chain complex (Open Access) Wang C, Richter‐Dennerlein R, (...), Rehling P EMBO reports 2019
A combined miRNA-piRNA signature to detect Alzheimer's disease (Open Access) Jain G, Stuendl A, (...), Fischer A Translational Psychiatry 2019
Modeling Fluorescence Correlation Spectroscopy through an aberrating sphere (Open Access) Ruhlandt D, Katti A, Derouard J, Delon A, Enderlein J arXiv 2019
Empirical optimal transport on countable metric spaces: Distributional limits and statistical applications Tameling C, Sommerfeld M, Munk A Annals of Applied Probability 2019
Circumvention of common labeling artifacts using secondary nanobodies (Open Access) Sograte-Idrissi S, Schlichthaerle T, (...), Opazo F bioRxiv 2019
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers (Open Access) Saravanan MS, Ryazanov S, (...), Killian JA Scientific Reports 2019
Autosomal-Recessive Mutations in MESD Cause Osteogenesis Imperfecta Moosa S, Yamamoto GL, (...), Netzer C American Journal of Human Genetics 2019
Graphene-based metal-induced energy transfer for sub-nanometre optical localization Ghosh A, Sharma A, (...), Enderlein J Nature Photonics 2019
Testing for dependence on tree structures (Open Access) Behr M, Ansari MA, Munk A, Holmes C bioRxiv 2019
Eukaryotic Transcription Turns 50 (Open Access) Cramer P Cell 2019
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer’s disease tau (Open Access) Brendel M, Deussing M, (...), Rominger A Alzheimers Research & Therapy 2019
Depopulation of dense α-synuclein aggregates is associated with rescue of dopamine neuron dysfunction and death in a new Parkinson’s disease model (Open Access) Wegrzynowicz M, Bar-On D, (...), Spillantini MG Acta Neuropathologica 2019
Structure of SWI/SNF chromatin remodeller RSC bound to a nucleosome (Open Access) Wagner FR, Dienemann C, (...), Cramer P bioRxiv 2019
Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes (Open Access) Hillen HS, Bartuli J, (...), Cramer P Cell 2019
Tricalbin-Mediated Contact Sites Control ER Curvature to Maintain Plasma Membrane Integrity (Open Access) Collado J, Kalemanov M, (...), Fernández-Busnadiego R Developmental Cell 2019
Structural Basis of Poxvirus Transcription: Vaccinia RNA Polymerase Complexes (Open Access) Grimm C, Hillen HS, (...), Fischer U Cell 2019
Mutation-induced alterations of intra-filament subunit organization in vimentin filaments revealed by SAXS (Open Access) Brennich ME, Vainio U, Wedig T, Bauch S, Herrmann H, Köster S Soft Matter 2019
A mass spectrometry workflow for measuring protein turnover rates in vivo Alevra M, Mandad S, Ischebeck T, Urlaub H, Rizzoli SO, Fornasiero EF Nature Protocols 2019
Multiscale quantile segmentation (Open Access) Vanegas LJ, Behr M, Munk A arXiv 2019
The essential histogram Li H, Munk A, Sieling H, Walther G Biometrika 2019
Loop formation and translational diffusion of intrinsically disordered proteins Mühle S, Zhou M, Ghosh A, Enderlein J Physical Review E 2019
The Essential Histogram (Open Access) Li H, Munk A, Sieling H, Walther G arXiv 2019
Structure of H3K36-methylated nucleosome–PWWP complex reveals multivalent cross-gyre binding Wang H, Farnung L, Dienemann C, Cramer P Nature Structural & Molecular Biology 2019
11C Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to α‐Synuclein Fibrils in vitro and Crosses the Blood‐Brain Barrier (Open Access) Maurer A, Leonov A, (...), Griesinger C ChemMedChem 2019
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43 (Open Access) Keihani S, Kluever V, (...), Fornasiero EF Science Advances 2019
Sharing Data from Molecular Simulations Abraham M, Apostolov R, (...), Zhmurov A Journal of Chemical Information and Modeling 2019
Dynamic instability of clathrin assembly provides proofreading control for endocytosis (Open Access) Chen Y, Yong J, (...), Wu M Journal of Cell Biology 2019
Contrast enhancement for visualizing neuronal cytoarchitecture by propagation-based x-ray phase-contrast tomography (Open Access) Töpperwien M, Markus A, Alves F, Salditt T Neuroimage 2019
Organization and regulation of gene transcription Cramer P Nature 2019
Loss of Protein Phosphatase 1 Regulatory Subunit PPP1R3A Promotes Atrial Fibrillation (Open Access) Alsina KM, Hulsurkar M, (...), Wehrens XH Circulation 2019
Molecular contribution function in RESOLFT nanoscopy (Open Access) Frahm L, Keller-Findeisen J, (...), Hell SW Optics Express 2019
Frame-constrained Total Variation Regularization for White Noise Regression (Open Access) del Álamo M, Li H, Munk A arXiv 2019
High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB (Open Access) Bartsch A, Llabrés S, (...), Steinem C Scientific Reports 2019
Multiscale change-point segmentation: beyond step functions (Open Access) Li H, Guo Q, Munk A Electronic Journal of Statistics 2019
A dual‐AAV approach restores fast exocytosis and partially rescues auditory function in deaf otoferlin knock‐out mice (Open Access) Al‐Moyed H, Cepeda AP, Jung S, Moser T, Kügler S, Reisinger E EMBO Molecular Medicine 2018
The codon sequences predict protein lifetimes and other parameters of the protein life cycle in the mouse brain (Open Access) Mandad S, Rahman R, (...), Fornasiero EF Scientific Reports 2018
Anle138b modulates α‐synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy (Open Access) Heras‐Garvin A, Weckbecker D, (...), Stefanova N Movement Disorders 2018