| Property |
Value |
| Working Groups |
RG Cyganek, 
RG Munk, 
RG Wollnik |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.64898/2026.08.18.745450 |
| Publication Year |
2026 |
| Title |
Distinct mitochondrial DNA single-nucleotide variant signatures in TOP3A-deficient cardiomyocytes |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.64898/2026.08.18.745450 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Not yet finally published in a peer-reviewed journal |
| Authors |
Gaubert M, Alachram H, Gönenç II, Domínguez I, Argyriou C, Schmidt J, Kaulfuß S, Pavez-Giani M, Schott CT, Munk A, Zibat A, Cyganek L, Yigit G, Wollnik B |
| First Author |
Gaubert M |
| Last Author |
Wollnik B |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.64898/2026.08.18.745450v1.full.pdf Article fulltext
2/180081https://publications.goettingen-research-online.de/handle/2/180081 GRO.publications identifier
0009-0007-6288-2984https://orcid.org/0009-0007-6288-2984 ORCID identifier (Marianne Gaubert)
0000-0002-4567-0775https://orcid.org/0000-0002-4567-0775 ORCID identifier (Halima Alachram)
0000-0002-7583-0872https://orcid.org/0000-0002-7583-0872 ORCID identifier (Ipek Ilgin Gönenc)
0000-0003-2577-9711https://orcid.org/0000-0003-2577-9711 ORCID identifier (Silke Kaulfuß)
0000-0002-3330-9384https://orcid.org/0000-0002-3330-9384 ORCID identifier (Mario Pavez-Giani)
0009-0003-7169-7503https://orcid.org/0009-0003-7169-7503 ORCID identifier (Constantin Tilman Schott)
0000-0002-9181-9331https://orcid.org/0000-0002-9181-9331 ORCID identifier (Axel Munk)
0000-0002-0837-3050https://orcid.org/0000-0002-0837-3050 ORCID identifier (Arne Zibat)
0000-0001-9120-1382https://orcid.org/0000-0001-9120-1382 ORCID identifier (Lukas Cyganek)
0000-0003-2777-0198https://orcid.org/0000-0003-2777-0198 ORCID identifier (Gökhan Yigit)
0000-0003-2589-0364https://orcid.org/0000-0003-2589-0364 ORCID identifier (Bernd Wollnik)
04ckbty56https://ror.org/04ckbty56 ROR identifier (04ckbty56, Cardio-Pulmonary Institute)
01s1h3j07https://ror.org/01s1h3j07 ROR identifier (01s1h3j07, Fraunhofer Institute for Translational Medicine and Pharmacology)
031t5w623https://ror.org/031t5w623 ROR identifier (031t5w623, German Centre for Cardiovascular Research)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
032nzv584https://ror.org/032nzv584 ROR identifier (032nzv584, University Hospital of Giessen and Marburg)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
035b05819https://ror.org/035b05819 ROR identifier (035b05819, University of Copenhagen)
033eqas34https://ror.org/033eqas34 ROR identifier (033eqas34, University of Giessen)
01y9bpm73https://ror.org/01y9bpm73 ROR identifier (01y9bpm73, University of Göttingen)
SCR_018435https://scicrunch.org/resolver/SCR_018435 SciCrunch identifier (RRID:SCR_018435, Agilent: 4200 TapeStation System)
SCR_019688https://scicrunch.org/resolver/SCR_019688 SciCrunch identifier (RRID:SCR_019688, Bio-Rad: C-1000 Thermal Cycler)
SCR_021693https://scicrunch.org/resolver/SCR_021693 SciCrunch identifier (RRID:SCR_021693, Bio-Rad: ChemiDoc Touch Imaging System)
SCR_010910https://scicrunch.org/resolver/SCR_010910 SciCrunch identifier (RRID:SCR_010910, BWA)
SCR_002344https://scicrunch.org/resolver/SCR_002344 SciCrunch identifier (RRID:SCR_002344, Ensembl)
SCR_014583https://scicrunch.org/resolver/SCR_014583 SciCrunch identifier (RRID:SCR_014583, FastQC)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_016387https://scicrunch.org/resolver/SCR_016387 SciCrunch identifier (RRID:SCR_016387, Illumina: NovaSeq 6000 Sequencing System)
SCR_013054https://scicrunch.org/resolver/SCR_013054 SciCrunch identifier (RRID:SCR_013054, LoFreq)
SCR_018550https://scicrunch.org/resolver/SCR_018550 SciCrunch identifier (RRID:SCR_018550, Minimap2)
SCR_006525https://scicrunch.org/resolver/SCR_006525 SciCrunch identifier (RRID:SCR_006525, Picard)
SCR_005227https://scicrunch.org/resolver/SCR_005227 SciCrunch identifier (RRID:SCR_005227, SAMtools/BCFtools)
SCR_023005https://scicrunch.org/resolver/SCR_023005 SciCrunch identifier (RRID:SCR_023005, Thermo Fisher: NanoDrop One/OneC Microvolume UV Vis Spectrophotometer)
biorxiv....-1.pdfhttps://www.biorxiv.org/content/biorxiv/early/2026/08/22/2026.08.18.745450/DC1/embed/media-1.pdf Supplemental material
mbexc.de...cytes/https://mbexc.de/distinct-mitochondrial-dna-single-nucleotide-variant-signatures-in-top3a-deficient-cardiomyocytes/ Website entry (mbexc.de)