| Property |
Value |
| Working Groups |
RG Fischer, 
RG Toischer |
| Subproject |
None |
| Open Access |
No |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
41327199 |
| DOI |
10.1186/s12964-025-02509-0 |
| Publication Year |
2025 |
| Title |
Deregulation of m6A-RNA methylation impairs adaptive hypertrophic response and drives maladaptation via mTORC1-S6K1-hyperactivation and autophagy impairment |
| Journal |
Cell Communication and Signaling |
| eISSN |
1478-811X |
| URL |
https://doi.org/10.1186/s12964-025-02509-0 |
| Journal Abbreviation |
Cell Commun Signal |
| Authors |
Annamalai K, Dilliker S, Buchholz E, Castro-Hernández R, Panyam N, Pommeranz A, Wiederhake P, Wery von Limont N, Hempel N, Ebner V, Swarnkar S, Mohamed BA, Streckfuss-Bömeke K, Steffens S, Herzig S, Ebert A, Fischer A, Toischer K |
| First Author |
Annamalai K |
| Last Author |
Toischer K |
External Resources
link.spr...-0.pdfhttps://link.springer.com/content/pdf/10.1186/s12964-025-02509-0.pdf Article fulltext
2/153309https://publications.goettingen-research-online.de/handle/2/153309 GRO.publications identifier
6436223https://pubchem.ncbi.nlm.nih.gov/compound/6436223 NCBI PubChem (6436223, Bafilomycin A1)
2719https://pubchem.ncbi.nlm.nih.gov/compound/2719 NCBI PubChem (2719, Chloroquine)
16212950https://pubchem.ncbi.nlm.nih.gov/compound/16212950 NCBI PubChem (16212950, Endothelin-1)
51371303https://pubchem.ncbi.nlm.nih.gov/compound/51371303 NCBI PubChem (51371303, PF-4708671)
5284616https://pubchem.ncbi.nlm.nih.gov/compound/5284616 NCBI PubChem (5284616, Sirolimus)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
0000-0002-7558-8035https://orcid.org/0000-0002-7558-8035 ORCID identifier (Karthika Annamalai)
0009-0007-5118-6908https://orcid.org/0009-0007-5118-6908 ORCID identifier (Soniya Dilliker)
0000-0003-3452-8017https://orcid.org/0000-0003-3452-8017 ORCID identifier (Eric Buchholz)
0009-0009-5224-131Xhttps://orcid.org/0009-0009-5224-131X ORCID identifier (Nikita Panyam)
0009-0006-2613-6426https://orcid.org/0009-0006-2613-6426 ORCID identifier (Pascal Wiederhake)
0009-0002-8665-6731https://orcid.org/0009-0002-8665-6731 ORCID identifier (Nelly Wery von Limont )
0009-0008-3180-5318https://orcid.org/0009-0008-3180-5318 ORCID identifier (Nina Hempel)
0009-0003-8046-1690https://orcid.org/0009-0003-8046-1690 ORCID identifier (Surabhi Swarnkar)
0000-0002-6705-3241https://orcid.org/0000-0002-6705-3241 ORCID identifier (Belal A. Mohamed)
0000-0001-5137-7228https://orcid.org/0000-0001-5137-7228 ORCID identifier (Katrin Streckfuß-Bömeke)
0000-0002-6892-9751https://orcid.org/0000-0002-6892-9751 ORCID identifier (Sabine Steffens)
0000-0003-3950-3652https://orcid.org/0000-0003-3950-3652 ORCID identifier (Stephan Herzig)
0000-0002-3642-242Xhttps://orcid.org/0000-0002-3642-242X ORCID identifier (Antje Dagmar Ebert)
0000-0001-8546-1161https://orcid.org/0000-0001-8546-1161 ORCID identifier (André Fischer)
0000-0002-9644-3716https://orcid.org/0000-0002-9644-3716 ORCID identifier (Karl Toischer)
565https://sfb1002.med.uni-goettingen.de/production/literature/publications/565 Published Data Registry entry (CRC 1002)
1/659https://mbexc.uni-goettingen.de/archive/1/659 Research Data Archive (supplemental material)
031t5w623https://ror.org/031t5w623 ROR identifier (031t5w623, German Centre for Cardiovascular Research)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
00cfam450https://ror.org/00cfam450 ROR identifier (00cfam450, Helmholtz Zentrum München)
02jet3w32https://ror.org/02jet3w32 ROR identifier (02jet3w32, Klinikum der Universität München)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
032nzv584https://ror.org/032nzv584 ROR identifier (032nzv584, Universitätsklinikum Gießen und Marburg)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
00fbnyb24https://ror.org/00fbnyb24 ROR identifier (00fbnyb24, University of Würzburg)
IMSR_JAX:011038https://scicrunch.org/resolver/IMSR_JAX:011038 SciCrunch identifier (RRID:IMSR_JAX:011038, B6.FVB-Tg(Myh6-cre)2182Mds/J)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_020132https://scicrunch.org/resolver/SCR_020132 SciCrunch identifier (RRID:SCR_020132, Illumina HiSeq2000 High Throughput Genetic Sequencer)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_015816https://scicrunch.org/resolver/SCR_015816 SciCrunch identifier (RRID:SCR_015816, Vevo 2100)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1186%2Fs12964-025-02509-0/MediaObjects/12964_2025_2509_MOESM1_ESM.pdf Supplemental material
static-c...M.docxhttps://static-content.springer.com/esm/art%3A10.1186%2Fs12964-025-02509-0/MediaObjects/12964_2025_2509_MOESM2_ESM.docx Supplemental material
mbexc.de...rment/https://mbexc.de/deregulation-of-m6a-rna-methylation-impairs-adaptive-hypertrophic-response-and-drives-maladaptation-via-mtorc1-s6k1-hyperactivation-and-autophagy-impairment/ Website entry (mbexc.de)