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Property	Value
Working Groups	RG Fernandez-Busnadiego
Subproject	RA2.1, RA2.2
Open Access	No
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	33909994
DOI	10.1016/j.str.2021.04.003
Publication Year	2021
Title	Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
Journal	Structure
ISSN	0969-2126
eISSN	1878-4186
URL	http://dx.doi.org/10.1016/j.str.2021.04.003
Journal Abbreviation	Structure
Authors	Huang B, Guo Q, Niedermeier ML, Cheng J, Engler T, Maurer M, Pautsch A, Baumeister W, Stengel F, Kochanek S, Fernández-Busnadiego R
First Author	Huang B
Last Author	Fernández-Busnadiego R

 External Resources

 cell.com...0119-2https://www.cell.com/structure/pdfExtended/S0969-2126(21)00119-2 Article fulltext

 EMD-3984https://www.ebi.ac.uk/pdbe/emdb/EMD-3984 EMBL-EBI EMDB identifier (EMD-3984)

 EMD-30911https://www.ebi.ac.uk/pdbe/emdb/EMD-30911 EMBL-EBI EMDB identifier (EMD-30911)

 EMD-30912https://www.ebi.ac.uk/pdbe/emdb/EMD-30912 EMBL-EBI EMDB identifier (EMD-30912)

 EMPIAR-10667https://www.ebi.ac.uk/empiar/EMPIAR-10667 EMBL-EBI EMPIAR identifier (EMPIAR-10667)

 2/86467https://publications.goettingen-research-online.de/handle/2/86467 GRO.publications identifier

 0000-0003-3520-5439https://orcid.org/0000-0003-3520-5439 ORCID identifier (Qiang Guo)

 0000-0001-8154-8809https://orcid.org/0000-0001-8154-8809 ORCID identifier (Wolfgang Baumeister)

 0000-0003-1447-4509https://orcid.org/0000-0003-1447-4509 ORCID identifier (Florian Stengel)

 0000-0001-7494-1602https://orcid.org/0000-0001-7494-1602 ORCID identifier (Stefan Kochanek)

 0000-0002-8366-7622https://orcid.org/0000-0002-8366-7622 ORCID identifier (Ruben Fernandez-Busnadiego)

 PXD018451http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD018451 Pride proteome dataset (PXD018451)

 231https://prod.mbexc.uni-goettingen.de/literature/publications/231 Published Data Registry entry (MBExC, preprint)

 1/548https://mbexc.uni-goettingen.de/archive/1/548 Research Data Archive (supplemental material)

 6EZ8https://www.rcsb.org/structure/6EZ8 RCSB PDB Identifier (6EZ8)

 7DXJhttps://www.rcsb.org/structure/7DXJ RCSB PDB Identifier (7DXJ)

 7DXKhttps://www.rcsb.org/structure/7DXK RCSB PDB Identifier (7DXK)

 05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

 021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)

 CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)

 SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)

 SCR_016732https://scicrunch.org/resolver/SCR_016732 SciCrunch identifier (RRID:SCR_016732, CTFFIND)

 SCR_014226https://scicrunch.org/resolver/SCR_014226 SciCrunch identifier (RRID:SCR_014226, MolProbity)

 SCR_016499https://scicrunch.org/resolver/SCR_016499 SciCrunch identifier (RRID:SCR_016499, MotionCor2)

 SCR_016736https://scicrunch.org/resolver/SCR_016736 SciCrunch identifier (RRID:SCR_016736, Phenix.refine)

 SCR_000305https://scicrunch.org/resolver/SCR_000305 SciCrunch identifier (RRID:SCR_000305, PyMOL)

 SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)

 SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)

 SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)

 SCR_015872https://scicrunch.org/resolver/SCR_015872 SciCrunch identifier (RRID:SCR_015872, UCSF ChimeraX)

 SCR_021010https://scicrunch.org/resolver/SCR_021010 SciCrunch identifier (RRID:SCR_021010, xiNET)

 SCR_021006https://scicrunch.org/resolver/SCR_021006 SciCrunch identifier (RRID:SCR_021006, xQuest)

 cell.com...c1.pdfhttps://www.cell.com/cms/10.1016/j.str.2021.04.003/attachment/8bde3aa2-c856-43e5-bb2e-9752583a1f27/mmc1.pdf Supplemental material

 goeseek.gwdguser.de/studies/214https://goeseek.gwdguser.de/studies/214 Supplemental material (goeseek study)

 cell.com...2.xlsxhttps://www.cell.com/cms/10.1016/j.str.2021.04.003/attachment/019a8d17-2884-450c-a385-765ef72b0706/mmc2.xlsx Supplemental material (table)

 mbexc.de...mplex/https://mbexc.de/pathological-polyq-expansion-does-not-alter-the-conformation-of-the-huntingtin-hap40-complex/ Website entry (mbexc.de)

Linked Antibodies

PID	AG	Type	Antigen symbol	Antibody Registry ID	Name
primary-0507		primary	FLAG	AB_259529	Monoclonal ANTI-FLAG® M2 antibody
primary-0508		primary	HTT	AB_2123254	Huntingtin Antibody
primary-0509		primary	F8A	AB_2278172	Goat Anti-HAP40 Polyclonal Antibody
primary-0510		primary	Strep	AB_513133	StrepMAB-Classic
primary-0602		primary	HTT	AB_532270	Anti-Polyglutamines antibody