View primary antibody

Basic data

PID primary-0602
EPIC PID
Research group RG Fernandez-Busnadiego
Quality (mean) no score (0.00)
Sharing level Public

Antibody data

Antigen symbol HTT
Antibody Registry ID(s) AB_532270
Name Anti-Polyglutamines antibody
Alternative name
Lab ID
Tag / Fluorophore
Raised in
Reacts with human
Clone 3B5H10
Isotype IgG1
Clonality monoclonal
Demasking unknown
Antigen
Crafted By company
Company / Manufacturer Sigma-Aldrich
Catalog no. P1874
Lot no.
Description immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: 1-2 μg/mL using extract of HEK-293T cells transfected with an N-terminal 171 amino acid fragment of human Huntingtin with a 68 glutamine stretch
Localization
Storage instruction storage temp. −20°C
Receipt date 2021-07-20 00:00:00
Preparation date 2021-07-20 00:00:00
Created by Klauenberg, Vanessa
Last modified Klauenberg, Vanessa

External links

Antibodypedia https://www.antibodypedia.com/gene/3449/HTT/antibody/90118/P1874
HGNC https://www.genenames.org/tools/search/#!/?query=HTT
Wikipedia https://en.wikipedia.org/wiki/HTT
Uniprot https://www.uniprot.org/uniprot/?query=HTT
GeneCards https://www.genecards.org/cgi-bin/carddisp.pl?gene=HTT
Antibody Registry https://antibodyregistry.org/search?q=AB_532270

Applications

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Linked publications

PolyQ expansion does not alter the Huntingtin-HAP40 complex
Huang B et al.
bioRxiv 2021: 10.1101/2021.02.02.429316
 
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
Huang B et al.
Structure 2021: 10.1016/j.str.2021.04.003