| Property |
Value |
| Working Groups |
RG Bohnsack, 
RG Richter-Dennerlein |
| Subproject |
RA1.1, RA1.2 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
35017528 |
| DOI |
10.1038/s41467-021-27905-1 |
| Publication Year |
2022 |
| Title |
The RNA methyltransferase METTL8 installs m3C32 in mitochondrial tRNAsThr/Ser(UCN) to optimise tRNA structure and mitochondrial translation |
| Journal |
Nature Communications |
| ISSN |
2041-1723 |
| eISSN |
2041-1723 |
| URL |
http://dx.doi.org/10.1038/s41467-021-27905-1 |
| Issue |
1 |
| Volume |
13 |
| Journal Abbreviation |
Nat Commun |
| Authors |
Kleiber N, Lemus-Diaz N, Stiller C, Heinrichs M, Mai MM, Hackert P, Richter-Dennerlein R, Höbartner C, Bohnsack KE, Bohnsack MT |
| First Author |
Kleiber N |
| Last Author |
Bohnsack MT |
External Resources
62988https://www.addgene.org/62988 Addgene identifier (62988, reused)
nature.c...-1.pdfhttps://www.nature.com/articles/s41467-021-27905-1.pdf Article fulltext
2/98794https://publications.goettingen-research-online.de/handle/2/98794 GRO.publications identifier
GSE174448https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174448 NCBI GEO Dataset (GSE174448)
GSE185015https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE185015 NCBI GEO Dataset (GSE185015)
0000-0003-0844-7547https://orcid.org/0000-0003-0844-7547 ORCID identifier (Nicole Kleiber)
0000-0001-7545-1656https://orcid.org/0000-0001-7545-1656 ORCID identifier (Nicolas Lemus-Diaz)
0000-0001-8904-1543https://orcid.org/0000-0001-8904-1543 ORCID identifier (Ricarda Richter-Dennerlein)
0000-0002-2534-7102https://orcid.org/0000-0002-2534-7102 ORCID identifier (Carina Stiller)
0000-0002-4548-2299https://orcid.org/0000-0002-4548-2299 ORCID identifier (Claudia Höbartner)
0000-0001-6035-4255https://orcid.org/0000-0001-6035-4255 ORCID identifier (Katherine Elizabeth Bohnsack)
0000-0001-7063-5456https://orcid.org/0000-0001-7063-5456 ORCID identifier (Markus T. Bohnsack)
167https://sfb1190.med.uni-goettingen.de/production/literature/publications/167 Published Data Registry entry (CRC 1190)
1/7https://mbexc.uni-goettingen.de/archive/1/7 Research Data Archive (supplemental material)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
01y9bpm73https://ror.org/01y9bpm73 ROR identifier (01y9bpm73, University of Göttingen)
00fbnyb24https://ror.org/00fbnyb24 ROR identifier (00fbnyb24, University of Würzburg)
CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)
CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)
SCR_001456https://scicrunch.org/resolver/SCR_001456 SciCrunch identifier (RRID:SCR_001456, BD FACSDiva)
SCR_002205https://scicrunch.org/resolver/SCR_002205 SciCrunch identifier (RRID:SCR_002205, flowCore)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_013715https://scicrunch.org/resolver/SCR_013715 SciCrunch identifier (RRID:SCR_013715, Image Studio)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-021-27905-1/MediaObjects/41467_2021_27905_MOESM1_ESM.pdf Supplemental material
goeseek.gwdguser.de/studies/116https://goeseek.gwdguser.de/studies/116 Supplemental material (goeseek study)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-021-27905-1/MediaObjects/41467_2021_27905_MOESM2_ESM.pdf Supplemental material (reporting summary)
static-c...SM.ziphttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-021-27905-1/MediaObjects/41467_2021_27905_MOESM3_ESM.zip Supplemental material (source data)
mbexc.de...ation/https://mbexc.de/the-rna-methyltransferase-mettl8-installs-m3c32-modifications-in-mitochondrial-trnathr-serucn-to-optimise-trna-structure-and-translation/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0111 |
 |
primary |
TUBA4A |
AB_477583 |
Anti-α-Tubulin antibody |
| primary-0298 |
|
primary |
MRPS14 |
AB_2878240 |
MRPS14 Polyclonal antibody |
| primary-0303 |
|
primary |
MRPL3 |
AB_10639509 |
MRPL3 Polyclonal antibody |
| primary-0306 |
|
primary |
MRPL44 |
AB_2146062 |
MRPL44 Polyclonal antibody |
| primary-0314 |
|
primary |
MFN2 |
AB_2266320 |
MFN2 Polyclonal antibody |
| primary-0315 |
|
primary |
TIMM44 |
AB_2204679 |
TIMM44 Polyclonal antibody |
| primary-0507 |
 |
primary |
FLAG |
AB_259529 |
Monoclonal ANTI-FLAG® M2 antibody |
| primary-0885 |
|
primary |
METTL8 |
AB_10670116 |
Anti-METTL8 antibody |
| primary-0888 |
|
primary |
OSGEPL1 |
AB_2813600 |
OSGEPL1 Polyclonal Antibody |
| primary-0889 |
|
primary |
TRIT1 |
AB_1858345 |
Anti-TRIT1 antibody |
| primary-0890 |
|
primary |
SARS2 |
|
Anti-SARS2 antibody |
| secondary-0070 |
 |
secondary |
|
AB_621847 |
IRDye® 800CW Donkey anti-Mouse IgG Secondary Antibody |
| secondary-0886 |
|
secondary |
|
AB_10715072 |
IRDye® 680LT Donkey anti-Mouse IgG Secondary Antibody |
| secondary-0887 |
|
secondary |
|
AB_2715510 |
IRDye® 800CW Donkey anti-Rabbit IgG Secondary Antibody |