| Property |
Value |
| Working Groups |
RG Fernandez-Busnadiego |
| Subproject |
RA2.1, RA2.2 |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
34933920 |
| DOI |
10.26508/lsa.202101185 |
| Publication Year |
2021 |
| Title |
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity |
| Journal |
Life Science Alliance |
| eISSN |
2575-1077 |
| URL |
http://dx.doi.org/10.26508/lsa.202101185 |
| Pages |
e202101185 |
| Issue |
3 |
| Volume |
5 |
| Journal Abbreviation |
Life Sci Alliance |
| Authors |
Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I |
| First Author |
Riera-Tur I |
| Last Author |
Dudanova I |
External Resources
110060https://www.addgene.org/110060 Addgene identifier (110060, reused)
life-sci...ll.pdfhttps://www.life-science-alliance.org/content/lsa/5/3/e202101185.full.pdf Article fulltext
2/97935https://publications.goettingen-research-online.de/handle/2/97935 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
0000-0002-2396-3921https://orcid.org/0000-0002-2396-3921 ORCID identifier (Irene Riera Tur)
0000-0002-9992-2501https://orcid.org/0000-0002-9992-2501 ORCID identifier (Tillman Schäfer)
0000-0002-6618-7774https://orcid.org/0000-0002-6618-7774 ORCID identifier (Daniel Hornburg)
0000-0003-1292-4799https://orcid.org/0000-0003-1292-4799 ORCID identifier (Matthias Mann)
0000-0003-1000-7989https://orcid.org/0000-0003-1000-7989 ORCID identifier (Felix Meissner)
0000-0002-5988-9129https://orcid.org/0000-0002-5988-9129 ORCID identifier (Nuno Raimundo)
0000-0002-8366-7622https://orcid.org/0000-0002-8366-7622 ORCID identifier (Ruben Fernandez-Busnadiego)
0000-0003-1052-8485https://orcid.org/0000-0003-1052-8485 ORCID identifier (Irina Dudanova)
5https://prod.mbexc.uni-goettingen.de/literature/publications/5 Published Data Registry entry (MBExC, preprint)
56https://rdp.sfb274.de/literature/publications/56 Published Data Registry entry (TRR 274)
1/340https://mbexc.uni-goettingen.de/archive/1/340 Research Data Archive (supplemental material)
04py35477https://ror.org/04py35477 ROR identifier (04py35477, Max Planck Institute of Biochemistry)
03ap2av50https://ror.org/03ap2av50 ROR identifier (03ap2av50, Max Planck Institute of Neurobiology)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
026zzn846https://ror.org/026zzn846 ROR identifier (026zzn846, Queen Mary University of London)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
041nas322https://ror.org/041nas322 ROR identifier (041nas322, University of Bonn)
0574dzy90https://ror.org/0574dzy90 ROR identifier (0574dzy90, William Harvey Research Institute)
CVCL_0030https://scicrunch.org/resolver/CVCL_0030 SciCrunch identifier (RRID:CVCL_0030, HeLa)
CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)
SCR_014199https://scicrunch.org/resolver/SCR_014199 SciCrunch identifier (RRID:SCR_014199, Adobe Photoshop)
SCR_007353https://scicrunch.org/resolver/SCR_007353 SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)
SCR_018738https://scicrunch.org/resolver/SCR_018738 SciCrunch identifier (RRID:SCR_018738, FEI Maps)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_003297https://scicrunch.org/resolver/SCR_003297 SciCrunch identifier (RRID:SCR_003297, IMOD)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)
SCR_014593https://scicrunch.org/resolver/SCR_014593 SciCrunch identifier (RRID:SCR_014593, Thermo Xcalibur)
goeseek.gwdguser.de/studies/120https://goeseek.gwdguser.de/studies/120 Supplemental material (goeseek study)
life-sci...d=truehttps://www.life-science-alliance.org/content/lsa/5/3/e202101185/DC1/embed/inline-supplementary-material-1.docx?download=true Supplemental material (table)
life-sci...d=truehttps://www.life-science-alliance.org/content/lsa/5/3/e202101185/DC2/embed/inline-supplementary-material-2.docx?download=true Supplemental material (table)
life-sci...d=truehttps://www.life-science-alliance.org/content/lsa/5/3/e202101185/DC3/embed/inline-supplementary-material-3.xlsx?download=true Supplemental material (table)
life-sci...d=truehttps://www.life-science-alliance.org/content/lsa/5/3/e202101185/DC4/embed/inline-supplementary-material-4.xlsx?download=true Supplemental material (table)
mbexc.de...icity/https://mbexc.de/amyloid-like-aggregates-cause-lysosomal-defects-in-neurons-via-gain-of-function-toxicity/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0156 |
|
primary |
mCherry |
AB_2333092 |
anti-mCherry antibody |
| primary-0157 |
|
primary |
MYC |
AB_2533008 |
c-Myc Monoclonal Antibody |
| primary-0158 |
|
primary |
CASP3 |
AB_2341188 |
Cleaved Caspase-3 (Asp175) Antibody |
| primary-0159 |
|
primary |
DDK |
AB_2622345 |
Anti-DDK (FLAG) monoclonal antibody |
| primary-0160 |
|
primary |
TUBA4A |
AB_477593 |
Anti-α-Tubulin antibody |
| primary-0161 |
|
primary |
ATG5 |
AB_2630393 |
Atg5 (D5F5U) antibody |
| primary-0366 |
|
primary |
SQSTM1 |
AB_945626 |
Anti-SQSTM1 / p62 antibody |
| primary-0546 |
 |
primary |
GFP |
AB_2313808 |
GFP antibody |
| primary-0871 |
|
primary |
AP3M1 |
AB_2715538 |
Recombinant Anti-AP3M1 antibody |
| primary-0872 |
|
primary |
LAMP1 |
AB_449893 |
Anti-LAMP1 antibody |
| primary-0873 |
|
primary |
MAP1LC3B |
AB_2137707 |
LC3B (D11) XP® Rabbit mAb |
| primary-0874 |
|
primary |
TUB |
AB_2884950 |
hFAB™ Rhodamine Anti-Tubulin Primary Antibody |
| primary-0875 |
|
primary |
BECN1 |
AB_1903911 |
Beclin-1 (D40C5) Rabbit mAb |
| primary-0876 |
|
primary |
HPRT1 |
AB_297217 |
Anti-HPRT antibody |
| primary-0877 |
|
primary |
AP3S1 |
|
AP3S1 Rabbit Polyclonal Antibody |