| Property |
Value |
| Working Groups |
RG Fernandez-Busnadiego |
| Subproject |
RA2.1 |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2021.03.15.435268 |
| Publication Year |
2021 |
| Title |
Gel-like inclusions of C-terminal fragments of TDP-43 sequester and inhibit proteasomes in neurons |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
http://dx.doi.org/10.1101/2021.03.15.435268 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Final article published in EMBO Reports here: doi:10.15252/embr.202153890 |
| Authors |
Riemenschneider H, Guo Q, Bader J, Frottin F, Farny D, Kleinberger G, Haass C, Mann M, Hartl FU, Baumeister W, Hipp MS, Meissner F, Fernandez-Busnadiego R, Edbauer D |
| First Author |
Riemenschneider H |
| Last Author |
Edbauer D |
External Resources
1186https://www.addgene.org/1186 Addgene identifier (reused)
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2021.03.15.435268v1.full.pdf Article fulltext
2/100379https://publications.goettingen-research-online.de/handle/2/100379 GRO.publications identifier
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
10116https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10116 NCBI taxonomy (rat, Rattus norvegicus)
0000-0003-3520-5439https://orcid.org/0000-0003-3520-5439 ORCID identifier (Qiang Guo)
0000-0002-6575-0609https://orcid.org/0000-0002-6575-0609 ORCID identifier (Jakob Maximilian Bader)
0000-0002-2756-7838https://orcid.org/0000-0002-2756-7838 ORCID identifier (Frédéric Frottin)
0000-0002-4869-1627https://orcid.org/0000-0002-4869-1627 ORCID identifier (Christian Haass)
0000-0003-1292-4799https://orcid.org/0000-0003-1292-4799 ORCID identifier (Matthias Mann)
0000-0002-7941-135Xhttps://orcid.org/0000-0002-7941-135X ORCID identifier (F. Ulrich Hartl)
0000-0001-8154-8809https://orcid.org/0000-0001-8154-8809 ORCID identifier (Wolfgang Baumeister)
0000-0002-0497-3016https://orcid.org/0000-0002-0497-3016 ORCID identifier (Mark S. Hipp)
0000-0003-1000-7989https://orcid.org/0000-0003-1000-7989 ORCID identifier (Felix Meissner)
0000-0002-8366-7622https://orcid.org/0000-0002-8366-7622 ORCID identifier (Ruben Fernandez-Busnadiego)
0000-0002-7186-4653https://orcid.org/0000-0002-7186-4653 ORCID identifier (Dieter Edbauer)
PXD024358http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD024358 Pride proteome dataset (PXD024358)
479https://prod.mbexc.uni-goettingen.de/literature/publications/479 Published Data Registry entry (MBExC, final article)
1/393https://mbexc.uni-goettingen.de/archive/1/393 Research Data Archive (supplemental material)
033n9gh91https://ror.org/033n9gh91 ROR identifier (033n9gh91, Carl von Ossietzky Universität Oldenburg)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
05591te55https://ror.org/05591te55 ROR identifier (05591te55, Ludwig-Maximilians-Universität München)
04py35477https://ror.org/04py35477 ROR identifier (04py35477, Max Planck Institute of Biochemistry)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
025z3z560https://ror.org/025z3z560 ROR identifier (025z3z560, Munich Cluster for Systems Neurology)
02v51f717https://ror.org/02v51f717 ROR identifier (02v51f717, Peking University)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
012p63287https://ror.org/012p63287 ROR identifier (012p63287, University of Groningen)
03xjwb503https://ror.org/03xjwb503 ROR identifier (03xjwb503, University of Paris-Saclay)
CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)
SCR_007353https://scicrunch.org/resolver/SCR_007353 SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)
SCR_018738https://scicrunch.org/resolver/SCR_018738 SciCrunch identifier (RRID:SCR_018738, FEI Maps)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_008520https://scicrunch.org/resolver/SCR_008520 SciCrunch identifier (RRID:SCR_008520, FlowJo)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_003297https://scicrunch.org/resolver/SCR_003297 SciCrunch identifier (RRID:SCR_003297, IMOD)
SCR_013673https://scicrunch.org/resolver/SCR_013673 SciCrunch identifier (RRID:SCR_013673, Leica Application Suite X)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_016499https://scicrunch.org/resolver/SCR_016499 SciCrunch identifier (RRID:SCR_016499, MotionCor 2)
SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_001905https://scicrunch.org/resolver/SCR_001905 SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)
SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)
SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)
SCR_000192https://scicrunch.org/resolver/SCR_000192 SciCrunch identifier (RRID:SCR_000192, TOM Toolbox)
SCR_018163https://scicrunch.org/resolver/SCR_018163 SciCrunch identifier (RRID:SCR_018163, ZEN Black)
SCR_013672https://scicrunch.org/resolver/SCR_013672 SciCrunch identifier (RRID:SCR_013672, ZEN Digital Imaging for Light Microscopy)
goeseek.gwdguser.de/studies/81https://goeseek.gwdguser.de/studies/81 Supplemental material (goeseek study)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/03/16/2021.03.15.435268/DC2/embed/media-2.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/03/16/2021.03.15.435268/DC3/embed/media-3.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/03/16/2021.03.15.435268/DC1/embed/media-1.mp4?download=true Supplemental material (video)
mbexc.de...urons/https://mbexc.de/gel-like-inclusions-of-c-terminal-fragments-of-tdp-43-sequester-and-inhibit-proteasomes-in-neurons/ Website entry (mbexc.de)
Q130454990https://www.wikidata.org/wiki/Q130454990 Wikidata ID
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0343 |
 |
primary |
CANX |
AB_10616095 |
Calnexin polyclonal antibody |
| primary-0637 |
|
primary |
pS403 |
AB_1961902 |
Anti-phospho TDP-43 (pS403/404) |
| primary-0638 |
|
primary |
MAP2 |
AB_477171 |
Anti-MAP2 (2a+2b) antibody |
| primary-0639 |
|
primary |
GFP |
AB_2313651 |
Anti-GFP antibody |