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Property	Value
Working Groups	RG Cramer
Subproject	None
Open Access	No
Publication Type	Journal Article
Peer Reviewed	Yes
PMID	33446560
DOI	10.1126/science.abf1870
Publication Year	2021
Title	Structure of a transcribing RNA polymerase II–U1 snRNP complex
Journal	Science
ISSN	0036-8075
eISSN	1095-9203
URL	http://dx.doi.org/10.1126/science.abf1870
Pages	305-309
Issue	6526
Volume	371
Journal Abbreviation	Science
Authors	Zhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer P
First Author	Zhang S
Last Author	Cramer P

 External Resources

 ahajourn...317581https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.317581 Article fulltext

 2/100174https://publications.goettingen-research-online.de/handle/2/100174 GRO.publications identifier

 EMD-11972https://www.ebi.ac.uk/pdbe/emdb/EMD-11972 EMBL-EBI EMDB identifier (EMD-11972)

 EMD-11973https://www.ebi.ac.uk/pdbe/emdb/EMD-11973 EMBL-EBI EMDB identifier (EMD-11973)

 EMD-11974https://www.ebi.ac.uk/pdbe/emdb/EMD-11974 EMBL-EBI EMDB identifier (EMD-11974)

 EMD-11975https://www.ebi.ac.uk/pdbe/emdb/EMD-11975 EMBL-EBI EMDB identifier (EMD-11975)

 PRJNA690001https://www.ncbi.nlm.nih.gov/bioproject/?term=PRJNA690001 NCBI bioproject identifier (PRJNA690001)

 9825https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9825 NCBI taxonomy (domestic pig, Sus scrofa domesticus)

 9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)

 0000-0002-2322-9276https://orcid.org/0000-0002-2322-9276 ORCID identifier (Suyang Zhang)

 0000-0003-2221-482Xhttps://orcid.org/0000-0003-2221-482X ORCID identifier (Shintaro Aibara)

 0000-0003-1985-2994https://orcid.org/0000-0003-1985-2994 ORCID identifier (Seychelle M. Vos)

 0000-0002-4438-4099https://orcid.org/0000-0002-4438-4099 ORCID identifier (Dmitry E. Agafonov)

 0000-0001-5454-7755https://orcid.org/0000-0001-5454-7755 ORCID identifier (Patrick Cramer)

 1/385https://mbexc.uni-goettingen.de/archive/1/385 Research Data Archive (supplemental material)

 7B0Yhttps://www.rcsb.org/structure/7B0Y RCSB PDB Identifier (DOI:10.2210/pdb7B0Y/pdb)

 042nb2s44https://ror.org/042nb2s44 ROR identifier (042nb2s44, Massachusetts Institute of Technology)

 03e76ya46https://ror.org/03e76ya46 ROR identifier (03e76ya46, Max Planck Institute for Biophysical Chemistry)

 05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)

 CVCL_0030https://scicrunch.org/resolver/CVCL_0030 SciCrunch identifier (RRID:CVCL_0030, HeLa)

 SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)

 SCR_006459https://scicrunch.org/resolver/SCR_006459 SciCrunch identifier (RRID:SCR_006459, Jalview)

 SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, Phenix)

 SCR_000305https://scicrunch.org/resolver/SCR_000305 SciCrunch identifier (RRID:SCR_000305, PyMOL)

 SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)

 SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)

 SCR_004097https://scicrunch.org/resolver/SCR_004097 SciCrunch identifier (RRID:SCR_004097, UCSF Chimera)

 SCR_015872https://scicrunch.org/resolver/SCR_015872 SciCrunch identifier (RRID:SCR_015872, UCSF ChimeraX)

 SCR_018071https://scicrunch.org/resolver/SCR_018071 SciCrunch identifier (RRID:SCR_018071, Warp)

 science....sm.pdfhttps://www.science.org/doi/suppl/10.1126/science.abf1870/suppl_file/abf1870_zhang_sm.pdf Supplemental material

 en.bio-p...bf1870https://en.bio-protocol.org/cjrap.aspx?eid=10.1126/science.abf1870 Supplemental material (protocol on request at bio-protocol.org)

 science....st.pdfhttps://www.science.org/doi/suppl/10.1126/science.abf1870/suppl_file/abf1870_mdar_reproducibility_checklist.pdf Supplemental material (reproducibility checklist)

 science....s1.mp4https://www.science.org/doi/suppl/10.1126/science.abf1870/suppl_file/abf1870_s1.mp4 Supplemental material (video)

 science....s2.mp4https://www.science.org/doi/suppl/10.1126/science.abf1870/suppl_file/abf1870_s2.mp4 Supplemental material (video)

 mbexc.de...mplex/https://mbexc.de/structure-of-a-transcribing-rna-polymerase-ii-u1-snrnp-complex/ Website entry (mbexc.de)

Linked Antibodies

PID	AG	Type	Antigen symbol	Antibody Registry ID	Name
primary-0496		primary	SNRNP70	AB_2801569	Anti-U1 snRNP 70 Antibody (C-3)
primary-0576		primary	POLR2C	AB_11218388	RPB3 Antibody
secondary-0497		secondary		AB_955389	Goat F(ab')2 Anti-Mouse IgG - H&L (HRP), pre-adsorbed
secondary-0670		secondary		AB_772206	Donkey Anti-Rabbit IgG, Whole Ab ECL Antibody