| Property |
Value |
| Working Groups |
RG Fernandez-Busnadiego |
| Subproject |
RA2.1 |
| Open Access |
No |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2019.12.16.877431 |
| Publication Year |
2019 |
| Title |
Amyloid-like aggregates cause lysosomal defects in neurons via gain-of-function toxicity |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
http://dx.doi.org/10.1101/2019.12.16.877431 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Final article published in Life Science Alliance here: doi:10.26508/lsa.202101185 |
| Authors |
Schaefer T, Riera-Tur I, Hornburg D, Mishra A, Fernández-Mosquera L, Raimundo N, Mann M, Baumeister W, Klein R, Meissner F, Fernández-Busnadiego R, Dudanova I |
| First Author |
Schaefer T |
| Last Author |
Dudanova I |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2019.12.16.877431v2.full.pdf Article fulltext
2/100230https://publications.goettingen-research-online.de/handle/2/100230 GRO.publications identifier
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
0000-0002-9992-2501https://orcid.org/0000-0002-9992-2501 ORCID identifier (Tillman Schäfer)
0000-0002-5988-9129https://orcid.org/0000-0002-5988-9129 ORCID identifier (Nuno Raimundo)
0000-0003-1292-4799https://orcid.org/0000-0003-1292-4799 ORCID identifier (Matthias Mann)
0000-0001-8154-8809https://orcid.org/0000-0001-8154-8809 ORCID identifier (Wolfgang Baumeister)
0000-0003-1000-7989https://orcid.org/0000-0003-1000-7989 ORCID identifier (Felix Meissner)
0000-0002-8366-7622https://orcid.org/0000-0002-8366-7622 ORCID identifier (Ruben Fernandez-Busnadiego)
0000-0003-1052-8485https://orcid.org/0000-0003-1052-8485 ORCID identifier (Irina Dudanova)
379https://prod.mbexc.uni-goettingen.de/literature/publications/379 Published Data Registry entry (MBExC, final article)
1/127https://mbexc.uni-goettingen.de/archive/1/127 Research Data Archive (supplemental material)
04py35477https://ror.org/04py35477 ROR identifier (04py35477, Max Planck Institute of Biochemistry)
03ap2av50https://ror.org/03ap2av50 ROR identifier (03ap2av50, Max Planck Institute of Neurobiology)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
026zzn846https://ror.org/026zzn846 ROR identifier (026zzn846, Queen Mary University of London)
00f54p054https://ror.org/00f54p054 ROR identifier (00f54p054, Stanford University)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
CVCL_0063https://scicrunch.org/resolver/CVCL_0063 SciCrunch identifier (RRID:CVCL_0063, HEK293T)
CVCL_0030https://scicrunch.org/resolver/CVCL_0030 SciCrunch identifier (RRID:CVCL_0030, HeLa)
SCR_014199https://scicrunch.org/resolver/SCR_014199 SciCrunch identifier (RRID:SCR_014199, Adobe Photoshop)
SCR_007353https://scicrunch.org/resolver/SCR_007353 SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)
SCR_018738https://scicrunch.org/resolver/SCR_018738 SciCrunch identfier (RRID:SCR_018738, FEI Maps)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_003297https://scicrunch.org/resolver/SCR_003297 SciCrunch identifier (RRID:SCR_003297, IMOD)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)
SCR_014593https://scicrunch.org/resolver/SCR_014593 SciCrunch identifier (RRID:SCR_014593, Thermo Xcalibur)
SCR_000192https://scicrunch.org/resolver/SCR_000192 SciCrunch identifier (RRID:SCR_000192, TOM toolbox)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/05/06/2019.12.16.877431/DC1/embed/media-1.xlsx?download=true Supplemental material (table)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2021/05/06/2019.12.16.877431/DC2/embed/media-2.xlsx?download=true Supplemental material (table)
mbexc.de...icity/https://mbexc.de/amyloid-like-aggregates-cause-lysosomal-defects-in-neurons-via-gain-of-function-toxicity/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0156 |
|
primary |
mCherry |
AB_2333092 |
anti-mCherry antibody |
| primary-0157 |
|
primary |
MYC |
AB_2533008 |
c-Myc Monoclonal Antibody |
| primary-0158 |
|
primary |
CASP3 |
AB_2341188 |
Cleaved Caspase-3 (Asp175) Antibody |
| primary-0159 |
|
primary |
DDK |
AB_2622345 |
Anti-DDK (FLAG) monoclonal antibody |
| primary-0160 |
|
primary |
TUBA4A |
AB_477593 |
Anti-α-Tubulin antibody |
| primary-0161 |
|
primary |
ATG5 |
AB_2630393 |
Atg5 (D5F5U) antibody |
| primary-0162 |
|
primary |
MAP1LC3B |
AB_2797680 |
LC3B (D11) XP® Rabbit mAb |