| Property |
Value |
| Working Groups |
RG Griesinger |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
42362792 |
| DOI |
10.1038/s44321-026-00459-9 |
| Publication Year |
2026 |
| Title |
Anle138b ameliorates pathological phenotypes in mouse and cellular models of Huntington’s disease |
| Journal |
EMBO Molecular Medicine |
| ISSN |
1757-4676 |
| eISSN |
1757-4684 |
| URL |
https://doi.org/10.1038/s44321-026-00459-9 |
| Journal Abbreviation |
EMBO Mol Med |
| Authors |
da Silva Padilha M, Koyuncu S, Chabanis E, Ryazanov S, Leonov A, Vilchez D, Klein R, Giese A, Griesinger C, Dudanova I |
| First Author |
da Silva Padilha M |
| Last Author |
Dudanova I |
External Resources
link.spr...-9.pdfhttps://link.springer.com/content/pdf/10.1038/s44321-026-00459-9.pdf Article fulltext
2/178292https://publications.goettingen-research-online.de/handle/2/178292 GRO.publications identifier
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
0000-0001-8141-7163https://orcid.org/0000-0001-8141-7163 ORCID identifier (Miguel da Silva Padilha)
0000-0001-7937-3974https://orcid.org/0000-0001-7937-3974 ORCID identifier (Seda Koyuncu)
0009-0002-2924-7085https://orcid.org/0009-0002-2924-7085 ORCID identifier (Evangeline Chabanis)
0000-0002-2685-7956https://orcid.org/0000-0002-2685-7956 ORCID identifier (Sergey Ryazanov)
0000-0002-5586-9382https://orcid.org/0000-0002-5586-9382 ORCID identifier (Andrei Leonov)
0000-0002-0801-0743https://orcid.org/0000-0002-0801-0743 ORCID identifier (David Vilchez)
0000-0002-3109-0163https://orcid.org/0000-0002-3109-0163 ORCID identifier (Rüdiger Klein)
0000-0002-8238-4102https://orcid.org/0000-0002-8238-4102 ORCID identifier (Armin Giese)
0000-0002-1266-4344https://orcid.org/0000-0002-1266-4344 ORCID identifier (Christian Griesinger)
0000-0003-1052-8485https://orcid.org/0000-0003-1052-8485 ORCID identifier (Irina Dudanova)
1188https://prod.mbexc.uni-goettingen.de/literature/publications/1188 Published Data Registry entry (MBExC, preprint)
1/743https://mbexc.uni-goettingen.de/archive/1/743 Research Data Archive (supplemental material)
04c4bwh63https://ror.org/04c4bwh63 ROR identifier (04c4bwh63, Cologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases)
03g267s60https://ror.org/03g267s60 ROR identifier (03g267s60, Max Planck Institute for Biological Intelligence)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
05mxhda18https://ror.org/05mxhda18 ROR identifier (05mxhda18, University Hospital Cologne)
00fbnyb24https://ror.org/00fbnyb24 ROR identifier (00fbnyb24, University of Würzburg)
IMSR_JAX:002810https://scicrunch.org/resolver/IMSR_JAX:002810 SciCrunch identifier (RRID:IMSR_JAX:002810, B6CBA-Tg(HDexon1)62Gpb/1J)
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SCR_014583https://scicrunch.org/resolver/SCR_014583 SciCrunch identifier (RRID:SCR_014583, FastQC)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_024569https://scicrunch.org/resolver/SCR_024569 SciCrunch identifier (RRID:SCR_024569, Illumina: NovaSeq X)
SCR_003070https://scicrunch.org/resolver/SCR_003070 SciCrunch identifier (RRID:SCR_003070, ImageJ)
SCR_013673https://scicrunch.org/resolver/SCR_013673 SciCrunch identifier (RRID:SCR_013673, Leica Application Suite X)
SCR_024663https://scicrunch.org/resolver/SCR_024663 SciCrunch identifier (RRID:SCR_024663, Leica STELLARIS 5 microscope)
SCR_023794https://scicrunch.org/resolver/SCR_023794 SciCrunch identifier (RRID:SCR_023794, Leica Thunder Imager Live Cell system)
SCR_016495https://scicrunch.org/resolver/SCR_016495 SciCrunch identifier (RRID:SCR_016495, Leica: VT1000S vibratome)
SCR_018042https://scicrunch.org/resolver/SCR_018042 SciCrunch identifier (RRID:SCR_018042, Thermo Fisher: NanoDrop 2000 Spectrophotometer)
SCR_028219https://scicrunch.org/resolver/SCR_028219 SciCrunch identifier (RRID:SCR_028219, Vilber Lourmat Fusion FX7 imaging system)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM1_ESM.pdf Supplemental material
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM20_ESM.pdf Supplemental material (figure)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM2_ESM.pdf Supplemental material (peer review)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM3_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM4_ESM.7z Supplemental material (source data)
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static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM7_ESM.7z Supplemental material (source data)
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static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM12_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM13_ESM.7z Supplemental material (source data)
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static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM15_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM16_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM17_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM18_ESM.7z Supplemental material (source data)
static-c...ESM.7zhttps://static-content.springer.com/esm/art%3A10.1038%2Fs44321-026-00459-9/MediaObjects/44321_2026_459_MOESM19_ESM.7z Supplemental material (source data)
mbexc.de...sease/https://mbexc.de/anle138b-ameliorates-pathological-phenotypes-in-mouse-and-cellular-models-of-huntingtons-disease/ Website entry (mbexc.de)