| Property |
Value |
| Working Groups |
RG Grubmüller |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
38730238 |
| DOI |
10.1038/s41467-024-48027-4 |
| Publication Year |
2024 |
| Title |
Multimodal binding and inhibition of bacterial ribosomes by the antimicrobial peptides Api137 and Api88 |
| Journal |
Nature Communications |
| ISSN |
2041-1723 |
| URL |
http://dx.doi.org/10.1038/s41467-024-48027-4 |
| Issue |
1 |
| Volume |
15 |
| Journal Abbreviation |
Nat Commun |
| Authors |
Lauer SM, Reepmeyer M, Berendes O, Klepacki D, Gasse J, Gabrielli S, Grubmüller H, Bock LV, Krizsan A, Nikolay R, Spahn CMT, Hoffmann R |
| First Author |
Lauer SM |
| Last Author |
Hoffmann R |
External Resources
nature.c...-4.pdfhttps://www.nature.com/articles/s41467-024-48027-4.pdf Article fulltext
EMD-19426https://www.ebi.ac.uk/pdbe/emdb/EMD-19426 EMBL-EBI EMDB identifier (EMD-19426)
EMD-19427https://www.ebi.ac.uk/pdbe/emdb/EMD-19427 EMBL-EBI EMDB identifier (EMD-19427)
EMD-19428https://www.ebi.ac.uk/pdbe/emdb/EMD-19428 EMBL-EBI EMDB identifier (EMD-19428)
EMD-19429https://www.ebi.ac.uk/pdbe/emdb/EMD-19429 EMBL-EBI EMDB identifier (EMD-19429)
679895https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=679895 NCBI taxonomy (Escherichia coli BW25113)
0000-0003-3518-5116https://orcid.org/0000-0003-3518-5116 ORCID identifier (Simon M. Lauer)
0009-0008-5822-9584https://orcid.org/0009-0008-5822-9584 ORCID identifier (Maren Reepmeyer)
0009-0003-1039-1148https://orcid.org/0009-0003-1039-1148 ORCID identifier (Ole Berendes)
0009-0006-0020-6019https://orcid.org/0009-0006-0020-6019 ORCID identifier (Jakob Gasse)
0000-0002-3021-6094https://orcid.org/0000-0002-3021-6094 ORCID identifier (Sara Gabrielli)
0000-0002-3270-3144https://orcid.org/0000-0002-3270-3144 ORCID identifier (Helmut Grubmüller)
0000-0003-4554-7336https://orcid.org/0000-0003-4554-7336 ORCID identifier (Lars V. Bock)
0000-0003-4713-2548https://orcid.org/0000-0003-4713-2548 ORCID identifier (Rainer Nikolay)
0000-0002-2939-9487https://orcid.org/0000-0002-2939-9487 ORCID identifier (Christian M. T. Spahn)
0000-0001-9932-5646https://orcid.org/0000-0001-9932-5646 ORCID identifier (Ralf Hoffmann)
PXD044892http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD044892 Pride proteome dataset (PXD044892, DOI:10.6069/3f7w-2t74)
5O2Rhttps://www.rcsb.org/structure/5O2R RCSB PDB Identifier (DOI:10.2210/pdb5O2R/pdb, reused)
7K00https://www.rcsb.org/structure/7K00 RCSB PDB Identifier (DOI:10.2210/pdb7K00/pdb, reused)
8RPYhttps://www.rcsb.org/structure/8RPY RCSB PDB Identifier (DOI:10.2210/pdb8RPY/pdb)
8RPZhttps://www.rcsb.org/structure/8RPZ RCSB PDB Identifier (DOI:10.2210/pdb8RPZ/pdb)
8RQ0https://www.rcsb.org/structure/8RQ0 RCSB PDB Identifier (DOI:10.2210/pdb8RQ0/pdb)
8RQ2https://www.rcsb.org/structure/8RQ2 RCSB PDB Identifier (DOI:10.2210/pdb8RQ2/pdb)
1/521https://mbexc.uni-goettingen.de/archive/1/521 Research Data Archive (supplemental material)
001w7jn25https://ror.org/001w7jn25 ROR identifier (001w7jn25, Charité - Universitätsmedizin Berlin)
01hcx6992https://ror.org/01hcx6992 ROR identifier (01hcx6992, Humboldt-Universität zu Berlin)
03s7gtk40https://ror.org/03s7gtk40 ROR identifier (03s7gtk40, Leipzig University)
03ate3e03https://ror.org/03ate3e03 ROR identifier (03ate3e03, Max Planck Institute for Molecular Genetics)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
02437s643https://ror.org/02437s643 ROR identifier (02437s643, University of Illinois Chicago, Rockford campus)
SCR_010279https://scicrunch.org/resolver/SCR_010279 SciCrunch identifier (RRID:SCR_010279, Adobe Illustrator)
SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)
SCR_016501https://scicrunch.org/resolver/SCR_016501 SciCrunch identifier (RRID:SCR_016501, cryoSPARC)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_014565https://scicrunch.org/resolver/SCR_014565 SciCrunch identifier (RRID:SCR_014565, GROMACS)
SCR_008624https://scicrunch.org/resolver/SCR_008624 SciCrunch identifier (RRID:SCR_008624, MatPlotLib)
SCR_016137https://scicrunch.org/resolver/SCR_016137 SciCrunch identifier (RRID:SCR_016137, Microsoft Excel)
SCR_023631https://scicrunch.org/resolver/SCR_023631 SciCrunch identifier (RRID:SCR_023631, Microsoft PowerPoint)
SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, Phenix)
SCR_000305https://scicrunch.org/resolver/SCR_000305 SciCrunch identifier (RRID:SCR_000305, PyMOL)
SCR_008394https://scicrunch.org/resolver/SCR_008394 SciCrunch identifier (RRID:SCR_008394, Python)
SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)
SCR_018132https://scicrunch.org/resolver/SCR_018132 SciCrunch identifier (RRID:SCR_018132, seaborn)
SCR_003210https://scicrunch.org/resolver/SCR_003210 SciCrunch identifier (RRID:SCR_003210, SigmaPlot)
SCR_015872https://scicrunch.org/resolver/SCR_015872 SciCrunch identifier (RRID:SCR_015872, UCSF ChimeraX)
SCR_018071https://scicrunch.org/resolver/SCR_018071 SciCrunch identifier (RRID:SCR_018071, Warp)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-024-48027-4/MediaObjects/41467_2024_48027_MOESM1_ESM.pdf Supplemental material
goeseek.gwdguser.de/studies/206https://goeseek.gwdguser.de/studies/206 Supplemental material (goeseek study)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-024-48027-4/MediaObjects/41467_2024_48027_MOESM2_ESM.pdf Supplemental material (peer review)
static-c...SM.pdfhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-024-48027-4/MediaObjects/41467_2024_48027_MOESM3_ESM.pdf Supplemental material (reporting summary)
static-c...M.xlsxhttps://static-content.springer.com/esm/art%3A10.1038%2Fs41467-024-48027-4/MediaObjects/41467_2024_48027_MOESM4_ESM.xlsx Supplemental material (source data)
10.5281/zenodo.10874716https://doi.org/10.5281/zenodo.10874716 Zenodo identifier (10.5281/zenodo.10874716)
mbexc.de...api88/https://mbexc.de/multimodal-binding-and-inhibition-of-bacterial-ribosomes-by-the-antimicrobial-peptides-api137-and-api88/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-1762 |
|
primary |
Biotin |
AB_2611059 |
Mouse Monoclonal 4C7.D5 IgG2a lambda |
| secondary-1763 |
|
secondary |
|
|
goat IgG anti-mouse IgG-Fc conjugated to gold nanoparticle |