| Property |
Value |
| Working Groups |
RG Fernandez-Busnadiego |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
38759629 |
| DOI |
10.1016/j.molcel.2024.04.018 |
| Publication Year |
2024 |
| Title |
Autophagy preferentially degrades non-fibrillar polyQ aggregates |
| Journal |
Molecular Cell |
| ISSN |
1097-2765 |
| URL |
http://dx.doi.org/10.1016/j.molcel.2024.04.018 |
| Pages |
1980-1994.e8 |
| Issue |
10 |
| Volume |
84 |
| Journal Abbreviation |
Mol Cell |
| Authors |
Zhao DY, Bäuerlein FJ, Saha I, Hartl FU, Baumeister W, Wilfling F |
| First Author |
Zhao DY |
| Last Author |
Wilfling F |
External Resources
scienced...in.pdfhttps://www.sciencedirect.com/science/article/pii/S1097276524003836/pdfft?md5=364da021e20b996748ae2a6ba601a157&pid=1-s2.0-S1097276524003836-main.pdf Article fulltext
40827https://www.addgene.org/40827 Addgene identifier (40827, reused)
45147https://www.addgene.org/45147 Addgene identifier (45147, reused)
48138https://www.addgene.org/48138 Addgene identifier (48138, reused)
84573https://www.addgene.org/84573 Addgene identifier (84573, reused)
98750https://www.addgene.org/98750 Addgene identifier (98750, reused)
175025https://www.addgene.org/175025 Addgene identifier (175025, reused)
10.17632/k66ygh2hy8.1https://doi.org/10.17632/k66ygh2hy8.1 DOI (10.17632/k66ygh2hy8.1, Mendeley dataset)
EMD-18110https://www.ebi.ac.uk/pdbe/emdb/EMD-18110 EMBL-EBI EMDB identifier (EMD-18110)
EMD-18114https://www.ebi.ac.uk/pdbe/emdb/EMD-18114 EMBL-EBI EMDB identifier (EMD-18114)
EMD-18115https://www.ebi.ac.uk/pdbe/emdb/EMD-18115 EMBL-EBI EMDB identifier (EMD-18115)
EMD-18116https://www.ebi.ac.uk/pdbe/emdb/EMD-18116 EMBL-EBI EMDB identifier (EMD-18116)
EMD-18117https://www.ebi.ac.uk/pdbe/emdb/EMD-18117 EMBL-EBI EMDB identifier (EMD-18117)
EMD-18118https://www.ebi.ac.uk/pdbe/emdb/EMD-18118 EMBL-EBI EMDB identifier (EMD-18118)
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (human, Homo sapiens)
0000-0002-8889-7371https://orcid.org/0000-0002-8889-7371 ORCID identifier (Felix J. B. Bäuerlein)
0000-0002-0289-4082https://orcid.org/0000-0002-0289-4082 ORCID identifier (Itika Saha)
0000-0002-7941-135Xhttps://orcid.org/0000-0002-7941-135X ORCID identifier (F. Ulrich Hartl)
0000-0001-8154-8809https://orcid.org/0000-0001-8154-8809 ORCID identifier (Wolfgang Baumeister)
0000-0002-6559-7261https://orcid.org/0000-0002-6559-7261 ORCID identifier (Florian Wilfling)
PXD04426http://proteomecentral.proteomexchange.org/cgi/GetDataset?ID=PXD04426 Pride proteome dataset (PXD04426)
1/516https://mbexc.uni-goettingen.de/archive/1/516 Research Data Archive (supplemental material)
03zj4c476https://ror.org/03zj4c476 ROR identifier (03zj4c476, Aligning Science Across Parkinson's)
02panr271https://ror.org/02panr271 ROR identifier (02panr271, Max Planck Institute of Biophysics)
04py35477https://ror.org/04py35477 ROR identifier (04py35477, Max Planck Institute of Biochemistry)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
AB_258167https://scicrunch.org/resolver/AB_258167 SciCrunch identifier (RRID:AB_258167)
AB_258434https://scicrunch.org/resolver/AB_258434 SciCrunch identifier (RRID:AB_258434)
AB_298039https://scicrunch.org/resolver/AB_298039 SciCrunch identifier (RRID:AB_298039)
AB_309938https://scicrunch.org/resolver/AB_309938 SciCrunch identifier (RRID:AB_309938)
AB_390913https://scicrunch.org/resolver/AB_390913 SciCrunch identifier (RRID:AB_390913)
AB_477583https://scicrunch.org/resolver/AB_477583 SciCrunch identifier (RRID:AB_477583)
AB_627695https://scicrunch.org/resolver/AB_627695 SciCrunch identifier (RRID:AB_627695)
AB_628423https://scicrunch.org/resolver/AB_628423 SciCrunch identifier (RRID:AB_628423)
AB_796155https://scicrunch.org/resolver/AB_796155 SciCrunch identifier (RRID:AB_796155)
AB_2196009https://scicrunch.org/resolver/AB_2196009 SciCrunch identifier (RRID:AB_2196009)
AB_2535849https://scicrunch.org/resolver/AB_2535849 SciCrunch identifier (RRID:AB_2535849)
AB_2920696https://scicrunch.org/resolver/AB_2920696 SciCrunch identifier (RRID:AB_2920696)
AB_3095587https://scicrunch.org/resolver/AB_3095587 SciCrunch identifier (RRID:AB_3095587)
AB_10003146https://scicrunch.org/resolver/AB_10003146 SciCrunch identifier (RRID:AB_10003146)
AB_10664137https://scicrunch.org/resolver/AB_10664137 SciCrunch identifier (RRID:AB_10664137)
AB_11150489https://scicrunch.org/resolver/AB_11150489 SciCrunch identifier (RRID:AB_11150489)
CVCL_0045https://scicrunch.org/resolver/CVCL_0045 SciCrunch identifier (RRID:CVCL_0045, HEK293)
CVCL_D3YThttps://scicrunch.org/resolver/CVCL_D3YT SciCrunch identifier (RRID:CVCL_D3YT, Neuro2a-tNhtt-EGFP-150Q)
CVCL_D3YShttps://scicrunch.org/resolver/CVCL_D3YS SciCrunch identifier (RRID:CVCL_D3YS, Neuro2a-tNhtt-EGFP-60Q)
SCR_010279https://scicrunch.org/resolver/SCR_010279 SciCrunch identifier (RRID:SCR_010279, Adobe Illustrator)
SCR_007353https://scicrunch.org/resolver/SCR_007353 SciCrunch identifier (RRID:SCR_007353, Advanced 3D Visualization and Volume Modeling)
SCR_013955https://scicrunch.org/resolver/SCR_013955 SciCrunch identifier (RRID:SCR_013955, Benchling)
SCR_002285https://scicrunch.org/resolver/SCR_002285 SciCrunch identifier (RRID:SCR_002285, Fiji)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_014237https://scicrunch.org/resolver/SCR_014237 SciCrunch identifier (RRID:SCR_014237, Huygens)
SCR_003297https://scicrunch.org/resolver/SCR_003297 SciCrunch identifier (RRID:SCR_003297, IMOD)
SCR_001622https://scicrunch.org/resolver/SCR_001622 SciCrunch identifier (RRID:SCR_001622, MATLAB)
SCR_014485https://scicrunch.org/resolver/SCR_014485 SciCrunch identifier (RRID:SCR_014485, MaxQuant)
SCR_016499https://scicrunch.org/resolver/SCR_016499 SciCrunch identifier (RRID:SCR_016499, MotionCor2)
SCR_015753https://scicrunch.org/resolver/SCR_015753 SciCrunch identifier (RRID:SCR_015753, Perseus)
SCR_008394https://scicrunch.org/resolver/SCR_008394 SciCrunch identifier (RRID:SCR_008394, Python)
SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)
SCR_003220https://scicrunch.org/resolver/SCR_003220 SciCrunch identifier (RRID:SCR_003220, Template-O-Matic Toolbox)
SCR_013672https://scicrunch.org/resolver/SCR_013672 SciCrunch identifier (RRID:SCR_013672, ZEN Digital Imaging for Light Microscopy)
SCR_024857https://scicrunch.org/resolver/SCR_024857 SciCrunch identifier (RRID:SCR_024857, Leica DM6 B Upright Microscope)
ars.els-...c1.pdfhttps://ars.els-cdn.com/content/image/1-s2.0-S1097276524003836-mmc1.pdf Supplemental material
github.c...orithmhttps://github.com/FJBauerlein/LisC_Algorithm Supplemental material (code, reused)
github.com/williamnwan/TOMOMANhttps://github.com/williamnwan/TOMOMAN Supplemental material (code, reused)
mbexc.de...gates/https://mbexc.de/autophagy-preferentially-degrades-non-fibrillar-polyq-aggregates/ Website entry (mbexc.de)
Linked Antibodies
| PID |
AG |
Type |
Antigen symbol |
Antibody Registry ID |
Name |
| primary-0111 |
 |
primary |
TUBA4A |
AB_477583 |
Anti-α-Tubulin antibody |
| primary-0193 |
|
primary |
VCP |
AB_298039 |
Anti-VCP antibody |
| primary-0344 |
 |
primary |
GFP |
AB_627695 |
Anti-GFP Antibody |
| primary-0784 |
 |
primary |
GFP |
AB_390913 |
Anti-GFP antibody |
| primary-0990 |
|
primary |
UBB |
AB_628423 |
Anti-Ubiquitin Antibody (P4D1) |
| primary-0997 |
|
primary |
MAP1LC3B |
AB_796155 |
Anti-LC3B antibody |
| primary-1727 |
|
primary |
Myc Tag |
AB_309938 |
Anti-Myc Tag Antibody, clone 4A6 |
| primary-1728 |
|
primary |
p62 |
AB_2196009 |
p62 (human) polyclonal antibody |
| primary-1729 |
|
primary |
ATN1 |
AB_2920696 |
Anti-polyQ specific Antibody, clone MW1 |
| primary-1731 |
|
primary |
MAP1LC3B |
AB_10003146 |
LC3B Antibody - BSA Free |
| primary-1732 |
|
primary |
|
AB_10664137 |
Beta-Actin Antibody |
| primary-1733 |
|
primary |
MAP1LC3B |
AB_11150489 |
LC3B Antikörper (G-9) |
| secondary-0019 |
 |
secondary |
|
AB_2535849 |
Goat anti-Rabbit IgG (H+L) Cross-Adsorbed Secondary Antibody, Alexa Fluor 555 |
| secondary-0376 |
|
secondary |
|
AB_258434 |
Anti-Rabbit IgG (whole molecule)–Peroxidase antibody |
| secondary-1003 |
|
secondary |
|
AB_258167 |
Anti-Mouse IgG (whole molecule)–Peroxidase antibody |
| secondary-1730 |
|
secondary |
|
AB_3095587 |
Anti-Mouse IgG (H+L), F(ab′)2 fragment, CF™350 antibody produced in goat |