| Property |
Value |
| Working Groups |
RG Fischer |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.64898/2026.02.08.704661 |
| Publication Year |
2026 |
| Title |
Multi-scale transcriptomic integration reveals cell-type immune networks and lncRNA remodeling in Alzheimer’s disease |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.64898/2026.02.08.704661 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Not yet finally published in a peer-reviewed journal |
| Authors |
Silva JAC, Gertig M, Centeno TP, Burkhardt S, Schütz A, Sananbenesi F, Fischer A |
| First Author |
Silva JAC |
| Last Author |
Fischer A |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.64898/2026.02.08.704661v1.full.pdf Article fulltext
2/163173https://publications.goettingen-research-online.de/handle/2/163173 GRO.publications identifier
GSE221959https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE221959 NCBI GEO Dataset (GSE221959)
GSE173242https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE173242 NCBI GEO Dataset (GSE173242)
GSE198027https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE198027 NCBI GEO Dataset (GSE198027)
GSE221702https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE221702 NCBI GEO Dataset (GSE221702)
10090https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=10090 NCBI taxonomy (mouse, Mus musculus)
9606https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=9606 NCBI taxonomy (mouse, Mus musculus)
0009-0006-8196-1314https://orcid.org/0009-0006-8196-1314 ORCID identifier (Jonathan Alexis Cortés Silva)
0000-0002-9329-8912https://orcid.org/0000-0002-9329-8912 ORCID identifier (Tonatiuh Pena Centeno)
0000-0001-7752-349Xhttps://orcid.org/0000-0001-7752-349X ORCID identifier (Susanne Burkhardt)
0000-0002-2123-7694https://orcid.org/0000-0002-2123-7694 ORCID identifier (Farahnaz Sananbenesi)
0000-0001-8546-1161https://orcid.org/0000-0001-8546-1161 ORCID identifier (André Fischer)
031t5w623https://ror.org/031t5w623 ROR identifier (031t5w623, German Center for Cardiovascular Diseases)
043j0f473https://ror.org/043j0f473 ROR identifier (043j0f473, German Center for Neurodegenerative Diseases)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
SCR_018043https://scicrunch.org/resolver/SCR_018043 SciCrunch identifier (RRID:SCR_018043, Agilent 2100 Bioanalyzer)
SCR_019214https://scicrunch.org/resolver/SCR_019214 SciCrunch identifier (RRID:SCR_019214, biomaRt)
SCR_016884https://scicrunch.org/resolver/SCR_016884 SciCrunch identifier (RRID:SCR_016884, clusterProfiler)
SCR_015687https://scicrunch.org/resolver/SCR_015687 SciCrunch identifier (RRID:SCR_015687, DESeq2)
SCR_026996https://scicrunch.org/resolver/SCR_026996 SciCrunch identifier (RRID:SCR_026996, enrichplot)
SCR_014601https://scicrunch.org/resolver/SCR_014601 SciCrunch identifier (RRID:SCR_014601, ggplot2)
SCR_020130https://scicrunch.org/resolver/SCR_020130 SciCrunch identifier (RRID:SCR_020130, Illumina HiSeq2000 Sequencing System)
SCR_023488https://scicrunch.org/resolver/SCR_023488 SciCrunch identifier (RRID:SCR_023488, org.Mm.eg.db)
SCR_001905https://scicrunch.org/resolver/SCR_001905 SciCrunch identifier (RRID:SCR_001905, R Project for Statistical Computing)
SCR_022146https://scicrunch.org/resolver/SCR_022146 SciCrunch identifier (RRID:SCR_022146, sctransform)
SCR_007322https://scicrunch.org/resolver/SCR_007322 SciCrunch identifier (RRID:SCR_007322, SEURAT)
SCR_018600https://scicrunch.org/resolver/SCR_018600 SciCrunch identifier (RRID:SCR_018600, Thermo Scientific NanoDrop 8000 Spectrophotometer)
SCR_020553https://scicrunch.org/resolver/SCR_020553 SciCrunch identifier (RRID:SCR_020553, Thermo Fisher Qubit 2.0 Fluorometer Qubit 2.0)
SCR_003302https://scicrunch.org/resolver/SCR_003302 SciCrunch identifier (RRID:SCR_003302, Weighted Gene Co-expression Network Analysis)
github.c...bilityhttps://github.com/jcortessilva/APP-RNAseq-reproducibility Supplemental material (code)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2026/02/10/2026.02.08.704661/DC1/embed/media-1.xlsx?download=true Supplemental material (table)
mbexc.de...sease/https://mbexc.de/multi-scale-transcriptomic-integration-reveals-cell-type-immune-networks-and-lncrna-remodeling-in-alzheimers-disease/ Website entry (mbexc.de)