| Property |
Value |
| Working Groups |
RG Dobbelstein, 
RG Ficner |
| Subproject |
None |
| Open Access |
No |
| Publication Type |
Journal Article |
| Peer Reviewed |
Yes |
| PMID |
40421686 |
| DOI |
10.1107/s2059798325004498 |
| Publication Year |
2025 |
| Title |
Myricetin-bound crystal structure of the SARS-CoV-2 helicase NSP13 facilitates the discovery of novel natural inhibitors |
| Journal |
Acta Crystallographica Section D-Structural Biology |
| ISSN |
2059-7983 |
| eISSN |
2059-7983 |
| URL |
https://doi.org/10.1107/s2059798325004498 |
| Pages |
310-326 |
| Issue |
6 |
| Volume |
81 |
| Journal Abbreviation |
Acta Crystallogr D Struct Biol |
| Authors |
Kloskowski P, Neumann P, Kumar P, Berndt A, Dobbelstein M, Ficner R |
| First Author |
Kloskowski P |
| Last Author |
Ficner R |
External Resources
journals...57.pdfhttps://journals.iucr.org/d/issues/2025/06/00/ud5057/ud5057.pdf Article fulltext
2/149477https://publications.goettingen-research-online.de/handle/2/149477 GRO.publications identifier
YP_009725308https://www.ncbi.nlm.nih.gov/protein/YP_009725308 NCBI protein identifier (YP_009725308, reused)
910270https://pubchem.ncbi.nlm.nih.gov/compound/910270 NCBI PubChem (910270, 2-phenoxy-1-(pyrrolidin-1-yl)ethan-1-one)
46886154https://pubchem.ncbi.nlm.nih.gov/compound/46886154 NCBI PubChem (46886154, 3,5,7-trihydroxychromone)
863558https://pubchem.ncbi.nlm.nih.gov/compound/863558 NCBI PubChem (863558, 4-(1H-1,3-benzodiazol-1-ylmethyl)benzonitrile)
31390https://pubchem.ncbi.nlm.nih.gov/compound/31390 NCBI PubChem (31390, 4-Amino-N-phenylbenzenesulfonamide)
1794427https://pubchem.ncbi.nlm.nih.gov/compound/1794427 NCBI PubChem (1794427, chlorogenic acid)
70807https://pubchem.ncbi.nlm.nih.gov/compound/70807 NCBI PubChem (70807, MOPS)
5281672https://pubchem.ncbi.nlm.nih.gov/compound/5281672 NCBI PubChem (5281672, myricetin)
1057https://pubchem.ncbi.nlm.nih.gov/compound/1057 NCBI PubChem (1057, pyrogallol)
5281792https://pubchem.ncbi.nlm.nih.gov/compound/5281792 NCBI PubChem (5281792, rosmarinic acid)
60711https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id=60711 NCBI taxonomy (green monkey, Chlorocebus sabaeus)
0009-0007-7077-0747https://orcid.org/0009-0007-7077-0747 ORCID identifier (Patrick Kloskowski)
0000-0003-0129-8112https://orcid.org/0000-0003-0129-8112 ORCID identifier (Piotr Neumann)
0009-0008-0060-1224https://orcid.org/0009-0008-0060-1224 ORCID identifier (Priya Kumar)
0000-0001-5052-3967https://orcid.org/0000-0001-5052-3967 ORCID identifier (Matthias Dobbelstein)
0000-0002-1739-6086https://orcid.org/0000-0002-1739-6086 ORCID identifier (Ralf Ficner)
9i1shttps://www.rcsb.org/structure/9i1s RCSB PDB Identifier (DOI:10.2210/pdb9i1s/pdb)
9i4vhttps://www.rcsb.org/structure/9i4v RCSB PDB Identifier (DOI:10.2210/pdb9i4v/pdb)
5rlchttps://www.rcsb.org/structure/5rlc RCSB PDB Identifier (DOI:10.2210/pdb5rlc/pdb, reused)
5rldhttps://www.rcsb.org/structure/5rld RCSB PDB Identifier (DOI:10.2210/pdb5rld/pdb, reused)
5rlzhttps://www.rcsb.org/structure/5rlz RCSB PDB Identifier (DOI:10.2210/pdb5rlz/pdb, reused)
5rmehttps://www.rcsb.org/structure/5rme RCSB PDB Identifier (DOI:10.2210/pdb5rme/pdb, reused)
5robhttps://www.rcsb.org/structure/5rob RCSB PDB Identifier (DOI:10.2210/pdb5rob/pdb, reused)
6zslhttps://www.rcsb.org/structure/6zsl RCSB PDB Identifier (DOI:10.2210/pdb6zsl/pdb, reused)
7krohttps://www.rcsb.org/structure/7kro RCSB PDB Identifier (DOI:10.2210/pdb7kro/pdb, reused)
7niohttps://www.rcsb.org/structure/7nio RCSB PDB Identifier (DOI:10.2210/pdb7nio/pdb, reused)
7nn0https://www.rcsb.org/structure/7nn0 RCSB PDB Identifier (DOI:10.2210/pdb7nn0/pdb, reused)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
021ft0n22https://ror.org/021ft0n22 ROR identifier (021ft0n22, University Medical Center Göttingen)
01y9bpm73https://ror.org/01y9bpm73 ROR identifier (01y9bpm73, University of Göttingen)
CVCL_0574https://scicrunch.org/resolver/CVCL_0574 SciCrunch identifier (RRID:CVCL_0574, Vero C1008)
SCR_007255https://scicrunch.org/resolver/SCR_007255 SciCrunch identifier (RRID:SCR_007255, CCP4)
SCR_014880https://scicrunch.org/resolver/SCR_014880 SciCrunch identifier (RRID:SCR_014880, OpenEye)
doi.org/...p1.pdfhttps://doi.org/10.1107/S2059798325004498/ud5057sup1.pdf Supplemental material (figure)