| Property |
Value |
| Working Groups |
RG Griesinger, 
RG de Groot |
| Subproject |
None |
| Open Access |
Yes |
| Publication Type |
Preprint |
| Peer Reviewed |
No |
| DOI |
10.1101/2025.04.21.649837 |
| Publication Year |
2025 |
| Title |
Structural insight into binding of novel PET tracer MODAG-005 to lipidic α-Synuclein fibrils |
| Journal |
bioRxiv |
| eISSN |
2692-8205 |
| URL |
https://doi.org/10.1101/2025.04.21.649837 |
| Journal Abbreviation |
bioRxiv |
| Extra |
Not yet finally published in a peer-reviewed journal |
| Authors |
Kim M, Matthes D, Frieg B, Leonov A, Ryazanov S, Bleher D, Grotegerd A, Dienemann C, Giese A, Schröder GF, Becker S, Herfert K, Groot BLd, Andreas LB, Griesinger C |
| First Author |
Kim M |
| Last Author |
Griesinger C |
External Resources
biorxiv....ll.pdfhttps://www.biorxiv.org/content/10.1101/2025.04.21.649837v1.full.pdf Article fulltext
EMD-52038https://www.ebi.ac.uk/pdbe/emdb/EMD-52038 EMBL-EBI EMDB identifier (EMD-52038)
EMD-52039https://www.ebi.ac.uk/pdbe/emdb/EMD-52039 EMBL-EBI EMDB identifier (EMD-52039)
EMD-52040https://www.ebi.ac.uk/pdbe/emdb/EMD-52040 EMBL-EBI EMDB identifier (EMD-52040)
EMD-52041https://www.ebi.ac.uk/pdbe/emdb/EMD-52041 EMBL-EBI EMDB identifier (EMD-52041)
EMD-52042https://www.ebi.ac.uk/pdbe/emdb/EMD-52042 EMBL-EBI EMDB identifier (EMD-52042)
EMD-52043https://www.ebi.ac.uk/pdbe/emdb/EMD-52043 EMBL-EBI EMDB identifier (EMD-52043)
2/178767https://publications.goettingen-research-online.de/handle/2/178767 GRO.publications identifier
0000-0003-0693-3090https://orcid.org/0000-0003-0693-3090 ORCID identifier (Myeongkyu Kim)
0000-0003-3969-6335https://orcid.org/0000-0003-3969-6335 ORCID identifier (Dirk Matthes)
0000-0002-7877-0262https://orcid.org/0000-0002-7877-0262 ORCID identifier (Benedikt Frieg)
0000-0002-5586-9382https://orcid.org/0000-0002-5586-9382 ORCID identifier (Andrei Leonov)
0000-0002-2216-2524https://orcid.org/0000-0002-2216-2524 ORCID identifier (Daniel Bleher)
0009-0002-2717-0723https://orcid.org/0009-0002-2717-0723 ORCID identifier (Ann-Kathrin Grotegerd)
0000-0002-2172-5110https://orcid.org/0000-0002-2172-5110 ORCID identifier (Christian Dienemann)
0000-0002-8238-4102https://orcid.org/0000-0002-8238-4102 ORCID identifier (Armin Giese)
0000-0003-1803-5431https://orcid.org/0000-0003-1803-5431 ORCID identifier (Gunnar Schröder)
0000-0003-2041-5740https://orcid.org/0000-0003-2041-5740 ORCID identifier (Stefan Becker)
0000-0003-0231-7717https://orcid.org/0000-0003-0231-7717 ORCID identifier (Kristina Herfert)
0000-0003-3570-3534https://orcid.org/0000-0003-3570-3534 ORCID identifier (Bert L. de Groot)
0000-0003-3216-9065https://orcid.org/0000-0003-3216-9065 ORCID identifier (Loren B. Andreas)
0000-0002-1266-4344https://orcid.org/0000-0002-1266-4344 ORCID identifier (Christian Griesinger)
9hc6https://www.rcsb.org/structure/9hc6 RCSB PDB Identifier (DOI:10.2210/pdb9hc6/pdb)
9hc7https://www.rcsb.org/structure/9hc7 RCSB PDB Identifier (DOI:10.2210/pdb9hc7/pdb)
9hc8https://www.rcsb.org/structure/9hc8 RCSB PDB Identifier (DOI:10.2210/pdb9hc8/pdb)
9hc9https://www.rcsb.org/structure/9hc9 RCSB PDB Identifier (DOI:10.2210/pdb9hc9/pdb)
9hcahttps://www.rcsb.org/structure/9hca RCSB PDB Identifier (DOI:10.2210/pdb9hca/pdb)
9hcbhttps://www.rcsb.org/structure/9hcb RCSB PDB Identifier (DOI:10.2210/pdb9hcb/pdb)
8A4Lhttps://www.rcsb.org/structure/8A4L RCSB PDB Identifier (DOI:10.2210/pdb8A4L/pdb, reused)
8ADUhttps://www.rcsb.org/structure/8ADU RCSB PDB Identifier (DOI:10.2210/pdb8ADU/pdb, reused)
8A9Lhttps://www.rcsb.org/structure/8A9L RCSB PDB Identifier (DOI:10.2210/pdb8A9L/pdb, reused)
6XYQhttps://www.rcsb.org/structure/6XYQ RCSB PDB Identifier (DOI:10.2210/pdb6XYQ/pdb, reused)
1/750https://mbexc.uni-goettingen.de/archive/1/750 Research Data Archive (supplemental material)
03a1kwz48https://ror.org/03a1kwz48 ROR identifier (03a1kwz48, Eberhard Karls University Tübingen)
024z2rq82https://ror.org/024z2rq82 ROR identifier (024z2rq82, Heinrich Heine University Düsseldorf)
02nv7yv05https://ror.org/02nv7yv05 ROR identifier (02nv7yv05, Jülich Research Centre)
03av75f26https://ror.org/03av75f26 ROR identifier (03av75f26, Max Planck Institute for Multidisciplinary Sciences)
05xy1nn52https://ror.org/05xy1nn52 ROR identifier (05xy1nn52, Multiscale Bioimaging)
SCR_028514https://scicrunch.org/resolver/SCR_028514 SciCrunch identifier (RRID:SCR_028514, Bruker: Avance III HD Ascend 600 MHz NMR Spectrometer)
SCR_028484https://scicrunch.org/resolver/SCR_028484 SciCrunch identifier (RRID:SCR_028484, Bruker: Avance III HD Ascend 850 MHz NMR Spectrometer)
SCR_028508https://scicrunch.org/resolver/SCR_028508 SciCrunch identifier (RRID:SCR_028508, Bruker: Avance III HD 800 MHz NMR Spectrometer)
SCR_016984https://scicrunch.org/resolver/SCR_016984 SciCrunch identifier (RRID:SCR_016984, CCPN Analysis)
SCR_014892https://scicrunch.org/resolver/SCR_014892 SciCrunch identifier (RRID:SCR_014892, CHARMM)
SCR_014222https://scicrunch.org/resolver/SCR_014222 SciCrunch identifier (RRID:SCR_014222, Coot)
SCR_018392https://scicrunch.org/resolver/SCR_018392 SciCrunch identifier (RRID:SCR_018392, crYOLO)
SCR_016732https://scicrunch.org/resolver/SCR_016732 SciCrunch identifier (RRID:SCR_016732, CTFFIND4)
SCR_018050https://scicrunch.org/resolver/SCR_018050 SciCrunch identifier (RRID:SCR_018050, Eppendorf: 5418 R Centrifuge)
SCR_002798https://scicrunch.org/resolver/SCR_002798 SciCrunch identifier (RRID:SCR_002798, GraphPad Prism)
SCR_014565https://scicrunch.org/resolver/SCR_014565 SciCrunch identifier (RRID:SCR_014565, GROMACS)
SCR_014226https://scicrunch.org/resolver/SCR_014226 SciCrunch identifier (RRID:SCR_014226, MolProbity)
SCR_014224https://scicrunch.org/resolver/SCR_014224 SciCrunch identifier (RRID:SCR_014224, PHENIX)
SCR_016274https://scicrunch.org/resolver/SCR_016274 SciCrunch identifier (RRID:SCR_016274, RELION)
SCR_014228https://scicrunch.org/resolver/SCR_014228 SciCrunch identifier (RRID:SCR_014228, Sparky)
SCR_017293https://scicrunch.org/resolver/SCR_017293 SciCrunch identifier (RRID:SCR_017293, SerialEM)
SCR_018071https://scicrunch.org/resolver/SCR_018071 SciCrunch identifier (RRID:SCR_018071, Warp)
biorxiv....d=truehttps://www.biorxiv.org/content/biorxiv/early/2025/04/22/2025.04.21.649837/DC1/embed/media-1.pdf?download=true Supplemental material
mbexc.de...brils/https://mbexc.de/de/structural-insight-into-binding-of-novel-pet-tracer-modag-005-to-lipidic-%f0%9d%9b%bc-synuclein-fibrils/ Website entry (mbexc.de)