View primary antibody

Basic data

PID primary-0102
EPIC PID
Research group RG Zimmermann
Quality (mean) no score (0.00)
Sharing level Public

Antibody data

Antigen symbol ACTN2
Antibody Registry ID(s) AB_476766
Name Anti-α-Actinin (Sarcomeric) antibody
Alternative name
Lab ID
Tag / Fluorophore
Raised in
Reacts with fish, snake, frog, goat, hamster, pig, canine, mouse, feline, chicken, lizard, bovine, human, sheep, rat
Clone EA-53
Isotype IgG1
Clonality monoclonal
Demasking unknown
Antigen Kaninchen-Skelettα-Aktinin
Crafted By company
Company / Manufacturer Sigma-Aldrich
Catalog no. A7811
Lot no.
Description
Localization
Storage instruction Storage temperature −20°C
Receipt date 2021-01-28 00:00:00
Preparation date 2021-01-28 00:00:00
Created by Klauenberg, Vanessa
Last modified Klauenberg, Vanessa

External links

Antibodypedia https://www.antibodypedia.com/gene/1323/ACTN2/antibody/74878/A7811
HGNC https://www.genenames.org/tools/search/#!/?query=ACTN2
Wikipedia https://en.wikipedia.org/wiki/ACTN2
Uniprot https://www.uniprot.org/uniprot/?query=ACTN2
GeneCards https://www.genecards.org/cgi-bin/carddisp.pl?gene=ACTN2
Antibody Registry https://antibodyregistry.org/search?q=AB_476766

Applications

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Linked publications

Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
Montiel V et al.
Sci Transl Med 2020: 10.1126/scitranslmed.aay2176
 
Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes
Peper J et al.
Circ Res 2021: 10.1161/circresaha.119.316547
 
Selective optogenetic control of Gq signaling using human Neuropsin
Wagdi A et al.
Nat Commun 2022: 10.1038/s41467-022-29265-w
 
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
Busley AV et al.
Stem Cell Res 2023: 10.1016/j.scr.2023.103108
 
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes
Dai Y et al.
Circ Res 2023: 10.1161/circresaha.122.321157
 
Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing
Schreiber M et al.
Stem Cell Res 2023: 10.1016/j.scr.2023.103276
 
Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells
Schreiber M et al.
Stem Cell Res 2023: 10.1016/j.scr.2023.103295
 
Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy
Schwenzer N et al.
bioRxiv 2024: 10.1101/2024.02.26.582084
 
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
Busley AV et al.
Cell Rep 2024: 10.1016/j.celrep.2024.114448
 
Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts
Ruiz-Orera J et al.
Nat Cardiovasc Res 2024: 10.1038/s44161-024-00544-7
 
SarcAsM: AI-based multiscale analysis of sarcomere organization and contractility in cardiomyocytes
Härtter D et al.
bioRxiv 2025: 10.1101/2025.04.29.650605
 
Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome
Fell J et al.
Circulation 2026: 10.1161/circulationaha.125.074155