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Inhibition of aquaporin-1 prevents myocardial remodeling by blocking the transmembrane transport of hydrogen peroxide
Montiel V, Bella R, Michel LYM, Esfahani H, De Mulder D, Robinson EL, Deglasse J, Tiburcy M, Chow PH, Jonas J, Gilon P, Steinhorn B, Michel T, Beauloye C, Bertrand L, Farah C, Dei Zotti F, Debaix H, Bouzin C, Brusa D, Horman S, Vanoverschelde J, Bergmann O, Gilis D, Rooman M, Ghigo A, Geninatti-Crich S, Yool A, Zimmermann WH, Roderick HL, Devuyst O, Balligand J
Sci Transl Med 2020 : 10.1126/scitranslmed.aay2176

Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes
Peper J, Kownatzki-Danger D, Weninger G, Seibertz F, Pronto JR, Sutanto H, Pacheu Grau D, Hindmarsh R, Brandenburg S, Kohl T, Hasenfuβ G, Gotthardt M, Rog-Zielinska EA, Wollnik B, Rehling P, Urlaub H, Wegener JW, Heijman J, Voigt N, Cyganek L, Lenz C, Lehnart SE
Circ Res 2021 : 10.1161/circresaha.119.316547

Selective optogenetic control of Gq signaling using human Neuropsin
Wagdi A, Malan D, Sathyanarayanan U, Beauchamp JS, Vogt M, Zipf D, Beiert T, Mansuroglu B, Dusend V, Meininghaus M, Schneider L, Kalthof B, Wiegert JS, König GM, Kostenis E, Patejdl R, Sasse P, Bruegmann T
Nat Commun 2022 : 10.1038/s41467-022-29265-w

Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
Busley AV, Cyganek L
Stem Cell Res 2023 : 10.1016/j.scr.2023.103108

An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes
Dai Y, Ignatyeva N, Xu H, Wali R, Toischer K, Brandenburg S, Lenz C, Pronto J, Fakuade FE, Sossalla S, Zeisberg EM, Janshoff A, Kutschka I, Voigt N, Urlaub H, Rasmussen TB, Mogensen J, Lehnart SE, Hasenfuss G, Ebert A
Circ Res 2023 : 10.1161/circresaha.122.321157

Generation of Pelizaeus-Merzbacher disease (PMD) mutant (PLP1-C33Y) in induced pluripotent stem cell (iPSC) by CRISPR/Cas9 genome editing
Schreiber M, Zafeiriou M
Stem Cell Res 2023 : 10.1016/j.scr.2023.103276

Generation of a fluorescent oligodendrocyte reporter line in human induced pluripotent stem cells
Schreiber M, Zafeiriou M
Stem Cell Res 2023 : 10.1016/j.scr.2023.103295

Nanoscale architecture and dynamics of CaV1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy
Schwenzer N, Tsukanov R, Kohl T, Basak S, Seibertz F, Voigt N, Enderlein J, Lehnart SE
bioRxiv 2024 : 10.1101/2024.02.26.582084

Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
Busley AV, Gutiérrez-Gutiérrez O, Hammer E, Koitka F, Mirzaiebadizi A, Steinegger M, Pape C, Böhmer L, Schroeder H, Kleinsorge M, Engler M, Cirstea IC, Gremer L, Willbold D, Altmüller J, Marbach F, Hasenfuss G, Zimmermann WH, Reza Ahmadian M, Wollnik B, Cyganek L
Cell Rep 2024 : 10.1016/j.celrep.2024.114448

Evolution of translational control and the emergence of genes and open reading frames in human and non-human primate hearts
Ruiz-Orera J, Miller DC, Greiner J, Genehr C, Grammatikaki A, Blachut S, Mbebi J, Patone G, Myronova A, Adami E, Dewani N, Liang N, Hummel O, Muecke MB, Hildebrandt TB, Fritsch G, Schrade L, Zimmermann WH, Kondova I, Diecke S, van Heesch S, Hübner N
Nat Cardiovasc Res 2024 : 10.1038/s44161-024-00544-7