View primary antibody

Basic data

PID primary-0815
EPIC PID
Research group RG Lehnart
Quality (mean) no score (0.00)
Sharing level Public

Antibody data

Antigen symbol VCL
Antibody Registry ID(s) AB_477629
Name Monoclonal Anti-Vinculin antibody
Alternative name metavinculin
Lab ID
Tag / Fluorophore
Raised in
Reacts with bovine, canine, mouse, rat, turkey, human, chicken, frog
Clone hVIN-1
Isotype IgG1
Clonality monoclonal
Demasking unknown
Antigen purified human vinculin from uterus
Crafted By company
Company / Manufacturer Sigma-Aldrich
Catalog no. V9131
Lot no.
Description https://rdp.sfb1565.uni-goettingen.de/antibodies/primary/primary-0306 immunohistochemistry (frozen sections): suitable indirect immunofluorescence: 1:400 using cultured human fibroblasts western blot: 1:200 using extract of human fibroblasts
Localization
Storage instruction storage temp. −20°C
Receipt date 2021-10-01 00:00:00
Preparation date 2021-10-25 00:00:00
Created by Klauenberg, Vanessa
Last modified

External links

Antibodypedia https://www.antibodypedia.com/gene/884/VCL/antibody/99716/V9131
HGNC https://www.genenames.org/tools/search/#!/?query=VCL
Wikipedia https://en.wikipedia.org/wiki/VCL
Uniprot https://www.uniprot.org/uniprot/?query=VCL
GeneCards https://www.genecards.org/cgi-bin/carddisp.pl?gene=VCL
Antibody Registry https://antibodyregistry.org/search?q=AB_477629

Applications

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Linked publications

The oxidation-resistant CaMKII-MM281/282VV mutation does not prevent arrhythmias in CPVT1
Sadredini M et al.
Physiol Rep 2021: 10.14814/phy2.15030
 
Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
Busley AV et al.
Stem Cell Res 2023: 10.1016/j.scr.2023.103105
 
Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
Busley AV et al.
Stem Cell Res 2023: 10.1016/j.scr.2023.103108
 
An Alternative Mechanism of Subcellular Iron Uptake Deficiency in Cardiomyocytes
Dai Y et al.
Circ Res 2023: 10.1161/circresaha.122.321157
 
Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
Busley AV et al.
Cell Rep 2024: 10.1016/j.celrep.2024.114448
 
Targeting Interleukin-8–Mediated Cellular Crosstalk Reverses Hypertrophic Cardiomyopathy and Cardiac Fibrosis in Noonan Syndrome
Fell J et al.
Circulation 2026: 10.1161/circulationaha.125.074155