View primary antibody

Basic data

PID primary-0185
EPIC PID
Research group RG Salditt
Quality (mean) no score (0.00)
Sharing level Public

Antibody data

Antigen symbol MAPT
Antibody Registry ID(s) AB_223647
Name Phospho-Tau (Ser202, Thr205) Monoclonal Antibody
Alternative name
Lab ID
Tag / Fluorophore
Raised in
Reacts with human, mouse, rat
Clone AT8
Isotype IgG1
Clonality monoclonal
Demasking unknown
Antigen Partially purified human PHF-Tau
Crafted By company
Company / Manufacturer Thermo Fisher Scientific
Catalog no. MN1020
Lot no.
Description Western Blot (WB) 1:250-1:2000 Immunohistochemistry (Paraffin) (IHC (P)) Assay Dependent Immunocytochemistry (ICC) 1:50-1:1000 Immunofluorescence (IF) 1:50-1:1000 ELISA (ELISA) Assay Dependent
Localization
Storage instruction -20° C, Avoid Freeze/Thaw Cycles
Receipt date 2021-03-12 00:00:00
Preparation date 2021-03-12 00:00:00
Created by Klauenberg, Vanessa
Last modified Klauenberg, Vanessa

External links

Antibodypedia https://www.antibodypedia.com/gene/3124/MAPT/antibody/561490/MN1020
HGNC https://www.genenames.org/tools/search/#!/?query=MAPT
Wikipedia https://en.wikipedia.org/wiki/MAPT
Uniprot https://www.uniprot.org/uniprot/?query=MAPT
GeneCards https://www.genecards.org/cgi-bin/carddisp.pl?gene=MAPT
Antibody Registry https://antibodyregistry.org/search?q=AB_223647

Applications

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Linked publications

Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease
Töpperwien M et al.
NeuroImage 2020: 10.1016/j.neuroimage.2020.116523
 
Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization
Dominguez-Meijide A et al.
Sci Rep 2020: 10.1038/s41598-020-69744-y
 
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation
Torres-Garcia L et al.
Researchsquare 2021: 10.21203/rs.3.rs-960446/v1
 
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I et al.
bioRxiv 2022: 10.1101/2022.02.18.481043
 
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
Torres-Garcia L et al.
Sci Rep 2022: 10.1038/s41598-022-06846-9
 
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
Saha I et al.
Nat Commun 2023: 10.1038/s41467-023-36058-2
 
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS
Chatterjee M et al.
Nat Med 2024: 10.1038/s41591-024-02937-4