Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
| PID | primary-0995 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0995 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
| Antigen symbol | MAPT |
| Antibody Registry ID(s) | AB_10980631 |
| Name | Tau Monoclonal Antibody |
| Alternative name | G protein beta1/gamma2 subunit-interacting factor 1 |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | bovine, human, mouse, sheep, rat |
| Clone | TAU-5 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Purified bovine microtubule-associated proteins |
| Crafted By | company |
| Company / Manufacturer | Thermo Fisher Scientific (Invitrogen) |
| Catalog no. | MA5-12808 |
| Lot no. | |
| Description | Western Blot (WB) 1-2 µg/mL Immunohistochemistry (Paraffin) (IHC (P)) 1:100 Immunocytochemistry (ICC/IF) 2-3 µg/mL Immunoprecipitation (IP) 2 µg/mg protein lysate |
| Localization | |
| Storage instruction | Storage conditions 4° C |
| Receipt date | 2022-03-18 00:00:00 |
| Preparation date | 2022-03-18 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS
Nat Commun 2023 : 10.1038/s41467-023-36058-2