Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0185 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0185 |
| Research group | RG Salditt |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | MAPT |
| Antibody Registry ID(s) | AB_223647 |
| Name | Phospho-Tau (Ser202, Thr205) Monoclonal Antibody |
| Alternative name | |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | Human, Mouse, Rat |
| Clone | AT8 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Partially purified human PHF-Tau |
| Crafted By | company |
| Company / Manufacturer | Thermo Fisher Scientific |
| Catalog no. | MN1020 |
| Lot no. | |
| Description | Western Blot (WB) 1:250-1:2000 Immunohistochemistry (Paraffin) (IHC (P)) Assay Dependent Immunocytochemistry (ICC) 1:50-1:1000 Immunofluorescence (IF) 1:50-1:1000 ELISA (ELISA) Assay Dependent |
| Localization | |
| Storage instruction | -20° C, Avoid Freeze/Thaw Cycles |
| Receipt date | 2021-03-12 00:00:00 |
| Preparation date | 2021-03-12 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
Applications
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Linked publications
Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease
Töpperwien M, van der Meer F, Stadelmann C, Salditt T
NeuroImage 2020 : 10.1016/j.neuroimage.2020.116523
Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization
Dominguez-Meijide A, Vasili E, König A, Cima-Omori M, Ibáñez de Opakua A, Leonov A, Ryazanov S, Zweckstetter M, Griesinger C, Outeiro TF
Sci Rep 2020 : 10.1038/s41598-020-69744-y
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation
Torres-Garcia L, Domingues JM, Brandi E, Haikal C, Brás IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li J
Researchsquare 2021 : 10.21203/rs.3.rs-960446/v1
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
Torres-Garcia L, P. Domingues JM, Brandi E, Haikal C, Mudannayake JM, Brás IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li J
Sci Rep 2022 : 10.1038/s41598-022-06846-9
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS
Nat Commun 2023 : 10.1038/s41467-023-36058-2
