Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0185 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0185 |
| Research group | RG Salditt |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | MAPT |
| Antibody Registry ID(s) | AB_223647 |
| Name | Phospho-Tau (Ser202, Thr205) Monoclonal Antibody |
| Alternative name | |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | human, mouse, rat |
| Clone | AT8 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Partially purified human PHF-Tau |
| Crafted By | company |
| Company / Manufacturer | Thermo Fisher Scientific |
| Catalog no. | MN1020 |
| Lot no. | |
| Description | Western Blot (WB) 1:250-1:2000 Immunohistochemistry (Paraffin) (IHC (P)) Assay Dependent Immunocytochemistry (ICC) 1:50-1:1000 Immunofluorescence (IF) 1:50-1:1000 ELISA (ELISA) Assay Dependent |
| Localization | |
| Storage instruction | -20° C, Avoid Freeze/Thaw Cycles |
| Receipt date | 2021-03-12 00:00:00 |
| Preparation date | 2021-03-12 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
Applications
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Linked publications
Correlative x-ray phase-contrast tomography and histology of human brain tissue affected by Alzheimer’s disease
Töpperwien M, van der Meer F, Stadelmann C, Salditt T
NeuroImage 2020 : 10.1016/j.neuroimage.2020.116523
Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization
Dominguez-Meijide A, Vasili E, König A, Cima-Omori M, Ibáñez de Opakua A, Leonov A, Ryazanov S, Zweckstetter M, Griesinger C, Outeiro TF
Sci Rep 2020 : 10.1038/s41598-020-69744-y
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation
Torres-Garcia L, Domingues JM, Brandi E, Haikal C, Brás IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li J
Researchsquare 2021 : 10.21203/rs.3.rs-960446/v1
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
Torres-Garcia L, P. Domingues JM, Brandi E, Haikal C, Mudannayake JM, Brás IC, Gerhardt E, Li W, Svanbergsson A, Outeiro TF, Gouras GK, Li J
Sci Rep 2022 : 10.1038/s41598-022-06846-9
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system
Saha I, Yuste-Checa P, Da Silva Padilha M, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Hartl FU, Hipp MS
Nat Commun 2023 : 10.1038/s41467-023-36058-2
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS
Chatterjee M, Özdemir S, Fritz C, Möbius W, Kleineidam L, Mandelkow E, Biernat J, Doğdu C, Peters O, Cosma NC, Wang X, Schneider LS, Priller J, Spruth E, Kühn AA, Krause P, Klockgether T, Vogt IR, Kimmich O, Spottke A, Hoffmann DC, Fliessbach K, Miklitz C, McCormick C, Weydt P, Falkenburger B, Brandt M, Guenther R, Dinter E, Wiltfang J, Hansen N, Bähr M, Zerr I, Flöel A, Nestor PJ, Düzel E, Glanz W, Incesoy E, Bürger K, Janowitz D, Perneczky R, Rauchmann BS, Hopfner F, Wagemann O, Levin J, Teipel S, Kilimann I, Goerss D, Prudlo J, Gasser T, Brockmann K, Mengel D, Zimmermann M, Synofzik M, Wilke C, Selma-González J, Turon-Sans J, Santos-Santos MA, Alcolea D, Rubio-Guerra S, Fortea J, Carbayo Á, Lleó A, Rojas-García R, Illán-Gala I, Wagner M, Frommann I, Roeske S, Bertram L, Heneka MT, Brosseron F, Ramirez A, Schmid M, Beschorner R, Halle A, Herms J, Neumann M, Barthélemy NR, Bateman RJ, Rizzu P, Heutink P, Dols-Icardo O, Höglinger G, Hermann A, Schneider A
Nat Med 2024 : 10.1038/s41591-024-02937-4
