Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0989 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0989 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | UBB |
| Antibody Registry ID(s) | AB_2895239 |
| Name | Recombinant Anti-Ubiquitin (linkage-specific K63) antibody [EPR8590-448] |
| Alternative name | polyubiquitin B |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | mouse, rat, human, RecombinantFragment |
| Clone | EPR8590-448 |
| Isotype | IgG |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Synthetic peptide within Human Ubiquitin aa 50-150 (linkage-specific K63) (Cysteine residue). |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab179434 |
| Lot no. | |
| Description | Flow Cyt (Intra) 1/210. WB 1/1000. Predicted molecular weight: 77 kDa. IHC-P 1/250 - 1/500. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. For unpurified, use 1/100 - 1/250. |
| Localization | Cell Membrane, Cytoplasmic and Nuclear |
| Storage instruction | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Receipt date | 2022-03-18 00:00:00 |
| Preparation date | 2022-03-18 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=UBB |
| Wikipedia | http://en.wikipedia.org/wiki/UBB |
| Uniprot | http://www.uniprot.org/uniprot/?query=UBB |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=UBB |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_2895239 |
Applications
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Linked publications
The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043
