Technical Support: support.menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
| PID | primary-0988 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0988 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
| Antigen symbol | VCP |
| Antibody Registry ID(s) | AB_2304347 |
| Name | p97/VCP Antibody |
| Alternative name | transitional endoplasmic reticulum ATPase |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | human, mouse, rat, zebrafish, porcine, bovine |
| Clone | |
| Isotype | IgG |
| Clonality | polyclonal |
| Demasking | unknown |
| Antigen | Recognizes immunogen, maps to a region between residue 750 and the C-terminus of human VCP |
| Crafted By | company |
| Company / Manufacturer | Novus Biologicals |
| Catalog no. | NB100-1558 |
| Lot no. | |
| Description | Immunocytochemistry/Immunofluorescence 1:100 - 1:500 Immunohistochemistry Immunohistochemistry-Frozen Immunoprecipitation 2-5 ug/mg of lysate Western Blot 1:2000 - 1:10000 |
| Localization | |
| Storage instruction | Store at 4C. Do not freeze. |
| Receipt date | 2022-03-18 00:00:00 |
| Preparation date | 2022-03-18 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
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The AAA+ chaperone VCP disaggregates Tau fibrils and generates aggregate seeds
Saha I, Yuste-Checa P, Silva Padilha MD, Guo Q, Körner R, Holthusen H, Trinkaus VA, Dudanova I, Fernández-Busnadiego R, Baumeister W, Sanders DW, Gautam S, Diamond MI, Ulrich Hartl F, Hipp MS
bioRxiv 2022 : 10.1101/2022.02.18.481043