Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0872 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0872 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | LAMP1 |
| Antibody Registry ID(s) | AB_449893 |
| Name | Anti-LAMP1 antibody |
| Alternative name | CD107a |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rat |
| Reacts with | human |
| Clone | 1D4B |
| Isotype | IgG2a |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Plasma membrane fraction of mouse embryo NIH3T3 cell line. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab25245 |
| Lot no. | |
| Description | IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. Flow Cyt (Intra) Use 1µg for 106 cells. ab18450 - Rat monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| Localization | Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane. |
| Storage instruction | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Receipt date | 2021-12-29 00:00:00 |
| Preparation date | 2021-12-29 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=LAMP1 |
| Wikipedia | http://en.wikipedia.org/wiki/LAMP1 |
| Uniprot | http://www.uniprot.org/uniprot/?query=LAMP1 |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=LAMP1 |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_449893 |
Applications
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Linked publications
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity
Riera-Tur I, Schäfer T, Hornburg D, Mishra A, da Silva Padilha M, Fernández-Mosquera L, Feigenbutz D, Auer P, Mann M, Baumeister W, Klein R, Meissner F, Raimundo N, Fernández-Busnadiego R, Dudanova I
Life Sci Alliance 2021 : 10.26508/lsa.202101185
Mouse oocytes sequester aggregated proteins in degradative super-organelles
Zaffagnini G, Cheng S, Salzer MC, Pernaute B, Duran JM, Irimia M, Schuh M, Böke E
Cell 2024 : 10.1016/j.cell.2024.01.031
