Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0861 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0861 |
| Research group | RG Rizzoli |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | LAMP1 |
| Antibody Registry ID(s) | AB_775978 |
| Name | Anti-LAMP1 antibody - Lysosome Marker |
| Alternative name | CD107 antigen like family member A antibody |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | human |
| Clone | |
| Isotype | IgG |
| Clonality | polyclonal |
| Demasking | unknown |
| Antigen | Synthetic peptide corresponding to Human LAMP1 aa 400 to the C-terminus conjugated to keyhole limpet haemocyanin. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab24170 |
| Lot no. | |
| Description | IHC-P Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol. WB Use a concentration of 1 µg/ml. Detects a band of approximately 90-130 kDa (predicted molecular weight: 120 kDa). Some variability in MW may be observed due to differing levels of glycosylation of the target protein in different cell/tissue types. Abcam recommends using Milk as the blocking agent. |
| Localization | Cell membrane. Endosome membrane. Lysosome membrane. This protein shuttles between lysosomes, endosomes, and the plasma membrane. |
| Storage instruction | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. |
| Receipt date | 2021-12-10 00:00:00 |
| Preparation date | 2021-12-10 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=LAMP1 |
| Wikipedia | http://en.wikipedia.org/wiki/LAMP1 |
| Uniprot | http://www.uniprot.org/uniprot/?query=LAMP1 |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=LAMP1 |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_775978 |
Applications
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Linked publications
Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R
Dankovich TM, Kaushik R, Olsthoorn LHM, Petersen GC, Giro PE, Kluever V, Agüi-Gonzalez P, Grewe K, Bao G, Beuermann S, Hadi HA, Doeren J, Klöppner S, Cooper BH, Dityatev A, Rizzoli SO
Nat Commun 2021 : 10.1038/s41467-021-27462-7
Mouse oocytes sequester aggregated proteins in degradative super-organelles
Zaffagnini G, Cheng S, Salzer MC, Pernaute B, Duran JM, Irimia M, Schuh M, Böke E
Cell 2024 : 10.1016/j.cell.2024.01.031
