Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0592 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0592 |
| Research group | RG Gärtner |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | APP |
| Antibody Registry ID(s) | AB_94882 |
| Name | Anti-APP A4 Antibody |
| Alternative name | peptidase nexin-II |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | canine, human, mouse, monkey, pig, rat, fish |
| Clone | 22C11 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Purified recombinant Alzheimer precursor A4 (pre A4695) fusion protein. |
| Crafted By | company |
| Company / Manufacturer | Merck Millipore |
| Catalog no. | MAB348 |
| Lot no. | |
| Description | TRR274: primary-0039 Immunofluorescence Immunohistochemistry: 5-10 μg/mL on 4% paraformaldehyde/15% picric acid perfused and fixed rat spinal cord. 22C11 also works in paraffin embedded tissues but at lower dilutions (1:10-1:20). Western blot: reducing conditions, 10μg/ml. Optimal working dilutions and protocols must be determined by the end user. |
| Localization | |
| Storage instruction | Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
| Receipt date | 2021-01-01 00:00:00 |
| Preparation date | 2021-07-12 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | , |
External links
Applications
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Linked publications
Concurrent axon and myelin destruction differentiates X-linked adrenoleukodystrophy from multiple sclerosis
Bergner CG, Genc N, Hametner S, Franz J, Meer F, Mitkovski M, Weber MS, Stoltenburg‐Didinger G, Kühl J, Köhler W, Brück W, Gärtner J, Stadelmann C
Glia 2021 : 10.1002/glia.24042
A large-scale nanoscopy and biochemistry analysis of postsynaptic dendritic spines
Helm MS, Dankovich TM, Mandad S, Rammner B, Jähne S, Salimi V, Koerbs C, Leibrandt R, Urlaub H, Schikorski T, Rizzoli SO
Nat Neurosci 2021 : 10.1038/s41593-021-00874-w
White matter integrity requires continuous myelin synthesis at the inner tongue
Meschkat M, Steyer AM, Weil M, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Ngoc Phan NT, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave K, Möbius W
bioRxiv 2020 : 10.1101/2020.09.02.279612
White matter integrity in mice requires continuous myelin synthesis at the inner tongue
Meschkat M, Steyer AM, Weil MT, Kusch K, Jahn O, Piepkorn L, Agüi-Gonzalez P, Ngoc Phan NT, Ruhwedel T, Sadowski B, Rizzoli SO, Werner HB, Ehrenreich H, Nave KA, Möbius W
Nat Commun 2022 : 10.1038/s41467-022-28720-y
