View primary antibody

Basic data

PIDprimary-0317
EPIC PIDhttps://hdl.handle.net/21.11124/primary-0317
Research groupRG Richter-Dennerlein
Quality (mean)no score (0.00)
Sharing levelPublic

Antibody data

Antigen symbolMT-CO2
Antibody Registry ID(s)AB_10887758
NameAnti-MTCO2 antibody
Alternative nameCOX2
Lab ID
Tag / Fluorophore
Raised inMouse
Reacts withhuman
Clone12C4F12
IsotypeIgG2a
Clonalitymonoclonal
Demaskingunknown
AntigenFull length native protein (purified).
Crafted Bycompany
Company / ManufacturerAbcam
Catalog no.ab110258
Lot no.
DescriptionWB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. ICC/IF Use a concentration of 5 - 10 µg/ml. (heat-induced antigen-retrieval improves signal) Flow Cyt Use a concentration of 1 µg/ml. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody.
LocalizationMitochondrion inner membrane.
Storage instructionShipped at 4°C. Store at +4°C.
Receipt date2021-04-13 00:00:00
Preparation date2021-04-13 00:00:00
Created byKlauenberg, Vanessa
Last modifiedKlauenberg, Vanessa

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Linked publications


Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes
Lavdovskaia E, Denks K, Nadler F, Steube E, Linden A, Urlaub H, Rodnina MV, Richter-Dennerlein R
Nucleic Acids Res 2020 : 10.1093/nar/gkaa1132

Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R
bioRxiv 2022 : 10.1101/2022.07.08.499411

Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R
Nat Commun 2022 : 10.1038/s41467-022-34088-w

Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria
Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, Das H, Kremer LS, Valpadashi A, Breuer M, Sattmann J, Richter-Dennerlein R, Warscheid B, Dennerlein S, Rehling P
Mol Cell 2024 : 10.1016/j.molcel.2023.12.013