Technical Support: support.menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0317 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0317 |
| Research group | RG Richter-Dennerlein |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | MT-CO2 |
| Antibody Registry ID(s) | AB_10887758 |
| Name | Anti-MTCO2 antibody |
| Alternative name | COX2 |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | human |
| Clone | 12C4F12 |
| Isotype | IgG2a |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Full length native protein (purified). |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab110258 |
| Lot no. | |
| Description | WB Use a concentration of 1 µg/ml. Predicted molecular weight: 26 kDa. ICC/IF Use a concentration of 5 - 10 µg/ml. (heat-induced antigen-retrieval improves signal) Flow Cyt Use a concentration of 1 µg/ml. ab170191 - Mouse monoclonal IgG2a, is suitable for use as an isotype control with this antibody. |
| Localization | Mitochondrion inner membrane. |
| Storage instruction | Shipped at 4°C. Store at +4°C. |
| Receipt date | 2021-04-13 00:00:00 |
| Preparation date | 2021-04-13 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=MT-CO2 |
| Wikipedia | http://en.wikipedia.org/wiki/MT-CO2 |
| Uniprot | http://www.uniprot.org/uniprot/?query=MT-CO2 |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=MT-CO2 |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_10887758 |
Applications
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Linked publications
Dual function of GTPBP6 in biogenesis and recycling of human mitochondrial ribosomes
Lavdovskaia E, Denks K, Nadler F, Steube E, Linden A, Urlaub H, Rodnina MV, Richter-Dennerlein R
Nucleic Acids Res 2020 : 10.1093/nar/gkaa1132
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R
bioRxiv 2022 : 10.1101/2022.07.08.499411
Human mtRF1 terminates COX1 translation and its ablation induces mitochondrial ribosome-associated quality control
Nadler F, Lavdovskaia E, Krempler A, Cruz-Zaragoza LD, Dennerlein S, Richter-Dennerlein R
Nat Commun 2022 : 10.1038/s41467-022-34088-w
Identification of TMEM126A as OXA1L-interacting protein reveals cotranslational quality control in mitochondria
Poerschke S, Oeljeklaus S, Cruz-Zaragoza LD, Schenzielorz A, Dahal D, Hillen HS, Das H, Kremer LS, Valpadashi A, Breuer M, Sattmann J, Richter-Dennerlein R, Warscheid B, Dennerlein S, Rehling P
Mol Cell 2024 : 10.1016/j.molcel.2023.12.013
Coupling of ribosome biogenesis and translation initiation in human mitochondria
Heinrichs M, Finke AF, Aibara S, Krempler A, Boshnakovska A, Rehling P, Hillen HS, Richter-Dennerlein R
Nat Commun 2025 : 10.1038/s41467-025-58827-x
