View primary antibody

Basic data

PID primary-0368
EPIC PID
Research group RG Fernandez-Busnadiego
Quality (mean) no score (0.00)
Sharing level Public

Antibody data

Antigen symbol SNCA
Antibody Registry ID(s) AB_398108
Name a-Synuclein antibody
Alternative name non A4 component of amyloid precursor
Lab ID
Tag / Fluorophore
Raised in
Reacts with rat, human, mouse
Clone 42
Isotype IgG1
Clonality monoclonal
Demasking unknown
Antigen Rat Synuclein-1 aa. 15-123
Crafted By company
Company / Manufacturer BD Biosciences
Catalog no. 610787
Lot no.
Description Western blot (Routinely Tested) Immunofluorescence (Tested During Development) Immunohistochemistry (Reported)
Localization
Storage instruction Store undiluted at -20°C.
Receipt date 2021-04-20 00:00:00
Preparation date 2021-04-20 00:00:00
Created by Klauenberg, Vanessa
Last modified Klauenberg, Vanessa

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Linked publications


In situ architecture of neuronal α-Synuclein inclusions
Trinkaus VA et al.
bioRxiv 2020: 10.1101/2020.08.07.234138
 
Effects of pharmacological modulators of α-synuclein and tau aggregation and internalization
Dominguez-Meijide A et al.
Sci Rep 2020: 10.1038/s41598-020-69744-y
 
Cofilin pathology is a new player on α-synuclein-induced spine impairment in models of hippocampal synucleinopathy
Oliveira da Silva M et al.
bioRxiv 2021: 10.1101/2021.02.02.425931
 
Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo
Albert K et al.
Mol Ther 2021: 10.1016/j.ymthe.2021.04.035
 
α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease
Stuendl A et al.
Mov Disord 2021: 10.1002/mds.28639
 
In situ architecture of neuronal α-Synuclein inclusions
Trinkaus VA et al.
Nat Commun 2021: 10.1038/s41467-021-22108-0
 
Common molecular mechanisms underlie the transfer of alpha-synuclein, Tau and huntingtin and modulate spontaneous activity in neuronal cells
Brás IC et al.
bioRxiv 2021: 10.1101/2021.07.18.452825
 
Monitoring Alpha-Synuclein – Tau Interactions In Vitro and In Vivo Using Bimolecular Fluorescence Complementation
Torres-Garcia L et al.
Researchsquare 2021: 10.21203/rs.3.rs-960446/v1
 
Monitoring the interactions between alpha-synuclein and Tau in vitro and in vivo using bimolecular fluorescence complementation
Torres-Garcia L et al.
Sci Rep 2022: 10.1038/s41598-022-06846-9
 
Nuclear alpha-synuclein is present in the human brain and is modified in dementia with Lewy bodies
Koss DJ et al.
bioRxiv 2021: 10.1101/2021.10.20.465125
 
Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations
Buratti FA et al.
Protein Sci 2022: 10.1002/pro.4360
 
JM-20, a Benzodiazepine-Dihydropyridine Hybrid Molecule, Inhibits the Formation of Alpha-Synuclein-Aggregated Species
Santos CC et al.
Neurotox Res 2022: 10.1007/s12640-022-00559-7
 
Changes in α-Synuclein Posttranslational Modifications in an AAV-Based Mouse Model of Parkinson’s Disease
Brembati V et al.
Int J Mol Sci 2023: 10.3390/ijms241713435
 
α-Synuclein triggers cofilin pathology and dendritic spine impairment via a PrPC-CCR5 dependent pathway
Oliveira da Silva MI et al.
Cell Death Dis 2024: 10.1038/s41419-024-06630-9
 
Lead as a toxic environmental toxicant in models of synucleinopathies
Shvachiy L et al.
bioRxiv 2024: 10.1101/2024.10.10.617554
 
Chronic Vanadium Exposure Promotes Aggregation of Alpha‐Synuclein, Tau and Amyloid Beta in Mouse Brain
Folarin OR et al.
J Neurochem 2025: 10.1111/jnc.70082