Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-1027 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-1027 |
| Research group | RG Gärtner |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | CLN5 |
| Antibody Registry ID(s) | |
| Name | Recombinant Anti-CLN5 antibody [EPR12197(B)] |
| Alternative name | ceroid-lipofuscinosis, neuronal 5 |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Rabbit |
| Reacts with | mouse, rat, human |
| Clone | EPR12197(B) |
| Isotype | IgG |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Synthetic peptide within Human CLN5 aa 150-250 (Cysteine residue). The exact sequence is proprietary. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab170899 |
| Lot no. | |
| Description | ab170899, ICC 1/50. For unpurified use at 1/100-1/250 dilution. WB (1) 1/1000 - 1/10000. Predicted molecular weight: 41 kDa. IHC-P 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. For unpurified use at 1/100-1/120 dilution. The mouse and rat recommendation is based on the WB results. We do not guarantee IHC-P for mouse and rat. |
| Localization | Lysosome. |
| Storage instruction | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Receipt date | 2022-01-01 00:00:00 |
| Preparation date | 2022-04-24 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | , |
External links
Applications
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Linked publications
Cln5 represents a new type of cysteine-based S-depalmitoylase linked to neurodegeneration
Luebben AV, Bender D, Becker S, Crowther LM, Erven I, Hofmann K, Söding J, Klemp H, Bellotti C, Stäuble A, Qiu T, Kathayat RS, Dickinson BC, Gärtner J, Sheldrick GM, Krätzner R, Steinfeld R
Sci Adv 2022 : 10.1126/sciadv.abj8633
