Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
| PID | primary-0602 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0602 |
| Research group | RG Fernandez-Busnadiego |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
| Antigen symbol | HTT |
| Antibody Registry ID(s) | AB_532270 |
| Name | Anti-Polyglutamines antibody |
| Alternative name | |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | human |
| Clone | 3B5H10 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | |
| Crafted By | company |
| Company / Manufacturer | Sigma-Aldrich |
| Catalog no. | P1874 |
| Lot no. | |
| Description | immunocytochemistry: suitable immunoprecipitation (IP): suitable western blot: 1-2 μg/mL using extract of HEK-293T cells transfected with an N-terminal 171 amino acid fragment of human Huntingtin with a 68 glutamine stretch |
| Localization | |
| Storage instruction | storage temp. −20°C |
| Receipt date | 2021-07-20 00:00:00 |
| Preparation date | 2021-07-20 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
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PolyQ expansion does not alter the Huntingtin-HAP40 complex
Huang B, Guo Q, Niedermeier ML, Cheng J, Engler T, Maurer M, Pautsch A, Baumeister W, Stengel F, Kochanek S, Fernández-Busnadiego R
bioRxiv 2021 : 10.1101/2021.02.02.429316
Pathological polyQ expansion does not alter the conformation of the Huntingtin-HAP40 complex
Huang B, Guo Q, Niedermeier ML, Cheng J, Engler T, Maurer M, Pautsch A, Baumeister W, Stengel F, Kochanek S, Fernández-Busnadiego R
Structure 2021 : 10.1016/j.str.2021.04.003