Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0559 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0559 |
| Research group | RG Outeiro |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | SNCA |
| Antibody Registry ID(s) | AB_302665 |
| Name | Anti-Alpha-synuclein antibody [4D6] |
| Alternative name | |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | human |
| Clone | 4D6 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Recombinant full length protein corresponding to Human Alpha-synuclein. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab1903 |
| Lot no. | |
| Description | WB 1/100 - 1/10000. Predicted molecular weight: 16 kDa. IHC-P 1/100 - 1/1000. Antigen retrieval is not essential but may optimise staining. |
| Localization | Cytoplasm, cytosol. Membrane. Nucleus. Cell junction, synapse. Secreted. Membrane-bound in dopaminergic neurons. |
| Storage instruction | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Receipt date | 2021-05-26 00:00:00 |
| Preparation date | 2021-05-26 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=SNCA |
| Wikipedia | http://en.wikipedia.org/wiki/SNCA |
| Uniprot | http://www.uniprot.org/uniprot/?query=SNCA |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=SNCA |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_302665 |
Applications
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Linked publications
Cerebral Dopamine Neurotrophic Factor Reduces α-Synuclein Aggregation and Propagation and Alleviates Behavioural Alterations in vivo
Albert K, Raymundo DP, Panhelainen A, Eesmaa A, Shvachiy L, Araújo GR, Chmielarz P, Yan X, Singh A, Cordeiro Y, Palhano FL, Foguel D, Luk KC, Domanskyi A, Voutilainen MH, Huttunen HJ, Outeiro TF, Saarma M, Almeida MS, Airavaara M
Mol Ther 2021 : 10.1016/j.ymthe.2021.04.035
