Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
      
      | PID | primary-0496 | 
| EPIC PID | https://hdl.handle.net/21.11124/primary-0496 | 
| Research group | RG Cramer | 
| Quality (mean) | no score (0.00) | 
| Sharing level | Public | 
| Antigen symbol | SNRNP70 | 
| Antibody Registry ID(s) | AB_2801569 | 
| Name | Anti-U1 snRNP 70 Antibody (C-3) | 
| Alternative name | U1-70K | 
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse | 
| Reacts with | mouse, human, rat | 
| Clone | C-3 | 
| Isotype | IgG1 | 
| Clonality | monoclonal | 
| Demasking | unknown | 
| Antigen | specific for an epitope mapping between amino acids 183-280 of U1 snRNP 70 of human origin | 
| Crafted By | company | 
| Company / Manufacturer | Santa Cruz Biotechnology | 
| Catalog no. | sc-390899 | 
| Lot no. | |
| Description | U1 snRNP 70 (C-3) is recommended for detection of U1 snRNP 70 of mouse, rat and human origin by Western Blotting (starting dilution 1:100, dilution range 1:100-1:1000), immunoprecipitation [1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)], immunofluorescence (starting dilution 1:50, dilution range 1:50-1:500), immunohistochemistry (including paraffin-embedded sections) (starting dilution 1:50, dilution range 1:50-1:500) and solid phase ELISA (starting dilution 1:30, dilution range 1:30-1:3000). | 
| Localization | |
| Storage instruction | Store at 4° C, **DO NOT FREEZE** | 
| Receipt date | 2021-05-07 00:00:00 | 
| Preparation date | 2021-05-07 00:00:00 | 
| Created by | Klauenberg, Vanessa | 
| Last modified | Klauenberg, Vanessa | 
| Antibodypedia | - | 
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=SNRNP70 | 
| Wikipedia | http://en.wikipedia.org/wiki/SNRNP70 | 
| Uniprot | http://www.uniprot.org/uniprot/?query=SNRNP70 | 
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=SNRNP70 | 
| Antibody Registry | http://antibodyregistry.org/search?q=AB_2801569 | 
No application comments yet.
Transcription activation depends on the length of the RNA polymerase II C‐terminal domain
Sawicka A, Villamil G, Lidschreiber M, Darzacq X, Dugast‐Darzacq C, Schwalb B, Cramer P
EMBO J 2021 : 10.15252/embj.2020107015
Structure of a transcribing RNA polymerase II–U1 snRNP complex
Zhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer P
Science 2021 : 10.1126/science.abf1870