Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
PID | primary-0496 |
EPIC PID | https://hdl.handle.net/21.11124/primary-0496 |
Research group | RG Cramer |
Quality (mean) | no score (0.00) |
Sharing level | Public |
Antigen symbol | SNRNP70 |
Antibody Registry ID(s) | AB_2801569 |
Name | Anti-U1 snRNP 70 Antibody (C-3) |
Alternative name | U1-70K |
Lab ID | |
Tag / Fluorophore | |
Raised in | Mouse |
Reacts with | mouse, human, rat |
Clone | C-3 |
Isotype | IgG1 |
Clonality | monoclonal |
Demasking | unknown |
Antigen | specific for an epitope mapping between amino acids 183-280 of U1 snRNP 70 of human origin |
Crafted By | company |
Company / Manufacturer | Santa Cruz Biotechnology |
Catalog no. | sc-390899 |
Lot no. | |
Description | U1 snRNP 70 (C-3) is recommended for detection of U1 snRNP 70 of mouse, rat and human origin by Western Blotting (starting dilution 1:100, dilution range 1:100-1:1000), immunoprecipitation [1-2 µg per 100-500 µg of total protein (1 ml of cell lysate)], immunofluorescence (starting dilution 1:50, dilution range 1:50-1:500), immunohistochemistry (including paraffin-embedded sections) (starting dilution 1:50, dilution range 1:50-1:500) and solid phase ELISA (starting dilution 1:30, dilution range 1:30-1:3000). |
Localization | |
Storage instruction | Store at 4° C, **DO NOT FREEZE** |
Receipt date | 2021-05-07 00:00:00 |
Preparation date | 2021-05-07 00:00:00 |
Created by | Klauenberg, Vanessa |
Last modified | Klauenberg, Vanessa |
Antibodypedia | - |
HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=SNRNP70 |
Wikipedia | http://en.wikipedia.org/wiki/SNRNP70 |
Uniprot | http://www.uniprot.org/uniprot/?query=SNRNP70 |
GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=SNRNP70 |
Antibody Registry | http://antibodyregistry.org/search?q=AB_2801569 |
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Transcription activation depends on the length of the RNA polymerase II C‐terminal domain
Sawicka A, Villamil G, Lidschreiber M, Darzacq X, Dugast‐Darzacq C, Schwalb B, Cramer P
EMBO J 2021 : 10.15252/embj.2020107015
Structure of a transcribing RNA polymerase II–U1 snRNP complex
Zhang S, Aibara S, Vos SM, Agafonov DE, Lührmann R, Cramer P
Science 2021 : 10.1126/science.abf1870