Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0416 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0416 |
| Research group | RG Rizzoli |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | TARDBP |
| Antibody Registry ID(s) | AB_10710019 |
| Name | Anti-TDP43 antibody [3H8] |
| Alternative name | ALS10 antibody |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | mouse, rat, human |
| Clone | 3H8 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Recombinant full length protein corresponding to Human TDP43. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab104223 |
| Lot no. | |
| Description | WB 1/5000. Predicted molecular weight: 45 kDa. ICC/IF 1/500. Flow Cyt 1/100. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. |
| Localization | Nucleus. In patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis, it is absent from the nucleus of affected neurons but it is the primary component of cytoplasmic ubiquitin-positive inclusion bodies. |
| Storage instruction | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Receipt date | 2021-04-24 00:00:00 |
| Preparation date | 2021-04-24 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=TARDBP |
| Wikipedia | http://en.wikipedia.org/wiki/TARDBP |
| Uniprot | http://www.uniprot.org/uniprot/?query=TARDBP |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=TARDBP |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_10710019 |
Applications
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Linked publications
The long noncoding RNA neuroLNC regulates presynaptic activity by interacting with the neurodegeneration-associated protein TDP-43
Keihani S, Kluever V, Mandad S, Bansal V, Rahman R, Fritsch E, Gomes LC, Gärtner A, Kügler S, Urlaub H, Wren JD, Bonn S, Rizzoli SO, Fornasiero EF
Sci Adv 2019 : 10.1126/sciadv.aay2670
