Technical Support: menoci@medizin.uni-goettingen.de
Department of Medical Informatics
University Medical Center Göttingen
Imprint
View primary antibody
Basic data
| PID | primary-0409 |
| EPIC PID | https://hdl.handle.net/21.11124/primary-0409 |
| Research group | RG Wollnik |
| Quality (mean) | no score (0.00) |
| Sharing level | Public |
Antibody data
| Antigen symbol | Rad50 |
| Antibody Registry ID(s) | AB_2176935 |
| Name | Anti-Rad50 antibody |
| Alternative name | DNA repair protein RAD50 antibody |
| Lab ID | |
| Tag / Fluorophore | |
| Raised in | Mouse |
| Reacts with | human |
| Clone | 13B3/2C6 |
| Isotype | IgG1 |
| Clonality | monoclonal |
| Demasking | unknown |
| Antigen | Fusion protein containing the complete coding region (amino acids 1-425) of RAD50 expressed in E.coli. |
| Crafted By | company |
| Company / Manufacturer | Abcam |
| Catalog no. | ab89 |
| Lot no. | |
| Description | Flow Cyt Use 1µg for 106 cells. ab170190 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody. IHC-P 1/100 - 1/1000. ICC 1/200. WB 1/500 - 1/3000. Detects a band of approximately 150 kDa (predicted molecular weight: 146 kDa). |
| Localization | Nucleus. Chromosome > telomere. Localizes to discrete nuclear foci after treatment with genotoxic agents. |
| Storage instruction | Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
| Receipt date | 2021-04-24 00:00:00 |
| Preparation date | 2021-04-24 00:00:00 |
| Created by | Klauenberg, Vanessa |
| Last modified | Klauenberg, Vanessa |
External links
| Antibodypedia | - |
| HGNC | http://www.genenames.org/cgi-bin/gene_symbol_report?match=Rad50 |
| Wikipedia | http://en.wikipedia.org/wiki/Rad50 |
| Uniprot | http://www.uniprot.org/uniprot/?query=Rad50 |
| GeneCards | http://www.genecards.org/cgi-bin/carddisp.pl?gene=Rad50 |
| Antibody Registry | http://antibodyregistry.org/search?q=AB_2176935 |
Applications
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Linked publications
Human RAD50 deficiency: Confirmation of a distinctive phenotype
Ragamin A, Yigit G, Bousset K, Beleggia F, Verheijen FW, Wit MY, Strom TM, Dörk T, Wollnik B, Mancini GMS
Am J Med Genet A 2020 : 10.1002/ajmg.a.61570
